scholarly journals Neonatal hepatitis in a term newborn: sequelae to in utero COVID-19 infection

2021 ◽  
Vol 8 (12) ◽  
pp. 1977
Author(s):  
Pushwinder Kaur
Keyword(s):  
Rare Case ◽  
Liver Parenchyma ◽  
In Utero ◽  
Postnatal Period ◽  
Neonatal Hepatitis ◽  
Vitamin Supplementation ◽  
Calorie Intake ◽  
Common Disease ◽  
High Grade Fever ◽  
Severe Jaundice

Neonatal hepatitis is a common disease entity seen among newborns. It is known as inflammation of liver parenchyma in newborns, specifically in first month of life. Most common cause of neonatal hepatitis is viral infection which infects liver in utero or in postnatal period. Newborns carrying neonatal hepatitis mostly present with jaundice, failure to gain weight and hepatosplenomegaly. Neonatal hepatitis due to in utero COVID infection is diagnosed by conjugated hyperbilirubinemia, raised SGOT and SGPT levels and raised COVID antibody levels.  Treatment includes addition of fat-soluble vitamins, phenobarbitone and supportive care. Here author is reporting a rare case of 11 days old newborn with neonatal hepatitis, who presented with severe jaundice (TSB/DB- 44/22) hepatosplenomegaly and hypoxemia with mild respiratory distress. Maternal history revealed high grade fever with low cell count during 5th month of gestation, though COVID RAT was negative and RT-PCR was not done. Baby was managed in NICU with IV antibiotics, IV fluids, oxygen by prongs, oral fat-soluble vitamin supplementation, adequate calorie intake and phenobarbitone. Baby responded very well to the treatment and discharged in healthy condition after 7 days. Paucity of data documenting in utero COVID-19 infection as cause of neonatal hepatitis led us to report this rare case.

scholarly journals Leishmania infantum and Epstein-Barr virus co-infection in a patient with hemophagocytosis

2017 ◽  
Vol 8 (4) ◽  
Author(s):  
Zied Gaifer ◽  
Mohamed-Rachid Boulassel
Keyword(s):  
Visceral Leishmaniasis ◽  
Complete Resolution ◽  
Liposomal Amphotericin ◽  
Rare Case ◽  
Epstein Barr Virus ◽  
Healthy Male ◽  
High Grade Fever ◽  
Barr Virus ◽  
Epstein Barr ◽  
Ebv Viremia

The authors describe a rare case of a 27-year old previously healthy male presenting with high grade fever, pancytopenia, hepatosplenomegaly, high levels of ferritin and triglyceride, suggesting a diagnosis of hemophagocytic lymphohistiocytosis (HLH) syndrome. Other investigations showed a positive <em>Leishmania</em> <em>infantum</em> serology and high Epstein-Barr virus (EBV) viremia. The diagnosis of a visceral leishmaniasis was confirmed by bone morrow biopsy, which showed Leishman-Donovan bodies and evidence of HLH. The patient received liposomal amphotericin B and he had a complete resolution of his symptoms and clearance of EBV viremia. This case of HLH associated with visceral leishmaniasis and EBV co-infection raises the question about the significance of EBV in patients with HLH. The treatment of actual etiological agent can lead to complete cure while using current recommend chemotherapy for HLH-related EBV in a patient with hidden infection may have deleterious effects.

scholarly journals Enhanced Asymptomatic Systemic Infection Caused by Plesiomonas shigelloides in a Captive Gray Wolf (Canis lupus)

2021 ◽  
Vol 8 (11) ◽  
pp. 280
Author(s):  
Kyootae Kim ◽  
Haeseung Lee ◽  
Dongmi Kwak
Keyword(s):  
Canis Lupus ◽  
Rare Case ◽  
Systemic Infection ◽  
Liver Parenchyma ◽  
Nucleotide Sequencing ◽  
Gray Wolf ◽  
Air Bubbles ◽  
Plesiomonas Shigelloides ◽  
Systemic Infections ◽  
Cultured Bacteria

A 7-year-old male gray wolf was found dead at a zoo during exhibition. To determine the cause of death, histological and gross necropsy diagnoses and a molecular analysis were performed. The gross necropsy revealed a swollen abdomen, hemorrhagic exudates around the mouth, splenomegaly, a discolored liver, a congested kidney, hemorrhagic ascites, and dark gray-colored membranes and air bubbles in the fundus of the stomach. Rod-shaped bacteria were found in the liver parenchyma and hemorrhagic ascites using Giemsa staining. The nucleotide sequencing of the cultured bacteria identified the causative agent as Plesiomonas shigelloides, which is rarely responsible for systemic infections. This study describes a rare case and the first reported systemic gastrointestinal infection due to P. shigelloides in a zoo animal.

scholarly journals A rare case of fetus papyraceous presenting in monozygotic biamniotic twins

2019 ◽  
Vol 9 (1) ◽  
pp. 448
Author(s):  
Lakshmi S. ◽  
Rajkumar K.
Keyword(s):  
Early Diagnosis ◽  
Rare Case ◽  
In Utero ◽  
Intrauterine Death ◽  
Second Trimester ◽  
Maternal Monitoring ◽  
Antenatal Visits ◽  
Live Baby

Fetus papyraceous or compresses is characteristic of compressed mummified, parchment like remains of dead twin retained in utero after intrauterine death in the second trimester. It is an uncommon finding and we report in a G2P1L1 with 22 weeks with Monozygoticbiamniotic twins with fetus papyraceous stuck to left upper segment followed up to 36 weeks. The mother was advised regular antenatal visits and frequent feto-maternal monitoring was done. Patient delivered a single live baby and a placenta with mummified fetus within it. The incidence of fetus papyraceous is about 1 in 17000 to 1 in 20000 pregnancies. Early diagnosis of this condition helps in monitoring the surviving fetus.

scholarly journals Cytomegalovirus Colitis with a Cobblestone Appearance

2020 ◽  
Vol 14 (2) ◽  
pp. 279-285
Author(s):  
Kimitoshi Kubo ◽  
Noriko Kimura ◽  
Soichiro Matsuda ◽  
Momoko Tsuda ◽  
Mototsugu Kato
Keyword(s):  
Sigmoid Colon ◽  
Rare Case ◽  
High Grade ◽  
Pathological Features ◽  
High Grade Fever ◽  
Lower Rectum ◽  
Mucosal Defect ◽  
Cytomegalovirus Colitis ◽  
Disturbance Of Consciousness ◽  
Cmv Colitis

Cytomegalovirus (CMV) colitis with a cobblestone appearance is rare, and its endoscopic and pathological features remain poorly described. A 78-year-old woman was admitted to our hospital for disturbance of consciousness, high-grade fever, and diarrhea occurring up to 7 times a day. Sigmoidoscopy revealed a circumferential ulcer with mucosal defect, an ulcer with a cobblestone appearance extending from the upper rectum to the sigmoid colon, and an irregular ulcer on the lower rectum. She was histopathologically diagnosed with CMV colitis and intravenously treated with ganciclovir (5 mg/kg) for 7 weeks. Colonoscopy after treatment revealed an improvement of the ulcers extending from the rectum to the sigmoid colon, but no significant improvement of her general condition. She died from sepsis 4 months after hospitalization. To our knowledge, this report represents a valuable addition to the CMV literature describing a rare case of CMV colitis with a cobblestone appearance.

scholarly journals Leptospirosis presented with erythema nodosum on four limbs: an unusual presenting

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Lotfollah Davoodi ◽  
Armaghan Kazeminejad ◽  
Hamed Jafarpour ◽  
Alireza Razavi
Keyword(s):  
Rare Case ◽  
Erythema Nodosum ◽  
Clinical Manifestations ◽  
Common Disease ◽  
Clinical Form ◽  
Case Presentation ◽  
Typical Form ◽  
Wide Range ◽  
Adipose Inflammation ◽  
Subcutaneous Adipose

Abstract Leptospirosis is a common disease between humans and animals characterized by a wide range of clinical manifestations. Erythema nodosum (EN) is a common clinical form of panniculitis or subcutaneous adipose inflammation caused by hypersensitivity responses to antigens, but the presence of EN in a subject with leptospirosis is a very rare case presentation. We will present a 42-year-old man with a headache, myalgia, nausea and rigid tender on the shin and both forearms, which was a typical form of EN lesions.

scholarly journals A Rare Case of Flare-Up of PID in Infertility Treatment

2015 ◽  
Vol 2015 ◽  
pp. 1-4
Author(s):  
Leena Wadhwa ◽  
Sanjana N. Wadhwa ◽  
Sunita Jindal
Keyword(s):  
Ovulation Induction ◽  
Rare Case ◽  
Infertility Treatment ◽  
Emergency Laparotomy ◽  
Low Grade ◽  
High Grade Fever ◽  
Genital Tuberculosis ◽  
Case Presentation ◽  
Aggressive Management ◽  
One Year

Case Presentation. Mrs. X, 35 years old, case of primary infertility, was diagnosed to have genital tuberculosis on the basis of PCR positive and hysterolaparoscopy findings and received category I ATT for 6 months. Following ATT completion, her USG revealed no evidence of tuboovarian mass or hydrosalpinx. Since her tubes were patent, she underwent 3 cycles of ovulation induction and 2 cycles of IUI. The women presented with acute PID, five days after IUI, and was conservatively managed. She again presented 24 days after IUI with persistent low grade fever and abdominal pain. Suspecting relapse of genital tuberculosis, she was started on category II ATT. She had acute episodes of high grade fever with chills 2 weeks after starting ATT and MRI revealed bilateral TO masses suggestive of pyosalpinx. Emergency laparotomy was done, pus was drained, and cyst wall was removed and HPE was suggestive of chronic inflammation with few granulation tissues. ATT was continued for one year and the woman improved.Conclusion. The possibility of flare-up of PID (pelvic inflammatory disease) in treated case of tuberculosis undergoing infertility management should be kept in mind and aggressive management should be done.

scholarly journals Scrub typhus, a rare of cause of fulminant hepatic failure: A common disease with uncommon presentation

2022 ◽  
pp. 526-528
Author(s):  
Subramani Jagadeesan ◽  
Pranav Patel ◽  
Ajay Jain
Keyword(s):  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Scrub Typhus ◽  
Kidney Injury ◽  
Asia Pacific ◽  
Common Disease ◽  
Antibiotic Administration ◽  
Elderly Male ◽  
High Grade Fever ◽  
Uncommon Presentation

Scrub typhus (bush typhus) is a potentially lethal mite-borne, acute febrile infectious illness caused by Orientia tsutsugamushi, reported precipitating frequent outbreaks in the Asia-pacific belt. Usual presentation after a median incubation period of 10–14 days, stretches from pathognomonic eschar, high-grade fever, centrifugal skin rash, jaundice, regional lymphadenopathy to frontal headache, nevertheless complicated at times with myocarditis, acute respiratory distress syndrome, acute kidney injury, encephalitis, and shock. Although patients with scrub typhus invariably do display mild liver injury, fulminant hepatic failure (FHF) is rarely reported. We describe herein, a case of FHF in an elderly male that responded well to antibiotics. Early diagnosis and sensitive antibiotic administration aids in mortality prevention of the former.

scholarly journals Facial cellulitis caused by Giant parotid sialolith: a minimally invasive treatment for a rare occurrence

2021 ◽  
Vol 10 (3) ◽  
pp. e58210313754
Author(s):  
Moacyr Tadeu Vicente Rodrigues ◽  
Filipe Ebenezer de Aguiar Schueng ◽  
Bruno Coelho Mendes ◽  
Jose Marcelo Vargas Pinto ◽  
Fabricio Guimaraes de Souza ◽  
...  
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Invasive Surgery ◽  
Rare Case ◽  
Treatment Protocol ◽  
Common Disease ◽  
Rare Occurrence ◽  
Parotid Glands ◽  
Invasive Treatment ◽  
And Function

Sialolithiasis is a common disease that affects the major salivary glands and can occur at any age. Parotid glands are rarely involved and, even rarer are the cases of sialoliths larger than 10 mm. This report presents the rare case of a giant parotid sialolith associated with facial cellulitis in a 75-year-old man. The treatment involved initially non-surgical approach followed by a minimally invasive surgery to restore health and function. The treatment protocol was completely successful and proved effective in clinical and surgical management of giant parotid sialolith associated with facial cellulitis.

scholarly journals LETTER TO THE EDITOR Is Pomegranate Juice Readily Available and Useful for the Management of Hypertension and the Improvement of Cardiovascular Health?

2013 ◽  
Vol 5 (1) ◽  
pp. 40-40 ◽  
Author(s):  
Fotios Barkas ◽  
Evangelos Liberopoulos
Keyword(s):  
Cardiovascular Risk ◽  
Weight Control ◽  
Cardiovascular Health ◽  
Beta Carotene ◽  
Alpha Tocopherol ◽  
Pomegranate Juice ◽  
Vitamin Supplementation ◽  
Calorie Intake ◽  
Antioxidant Vitamin ◽  
Long Term Effects

DEAR EDITOR, We read with interest the recent editorial by Tziomalos et al. on the potential benefit of pomegranate juice (PJ) in the management of hypertension and cardiovascular risk [1]. The authors conclude that PJ may be useful in the treatment of hypertensives, especially those with a high burden of oxidative stress. Although data on PJ seem promising no solid evidence exists to support its routine use by these patients. Certain issues that should be taken into account include: 1) Price and availability. PJ is rather expensive and may not be available worldwide. 2) Quantity and calorie intake. The suggested volume of intake varies among studies (150-240 mL) [2,3]. Calorie intake has to be considered in this regard. Recently it was shown that fruit juice compared with whole fruit consumption might be related with higher risk of type 2 diabetes [4]. 3) The studies showing a beneficial effect of PJ on cardiovascular risk factors included a small number of participants, were mostly not double blinded and evaluated only surrogate end-points. 4) The effect of PJ on blood pressure is rather small. 5) The long term effects of PJ are unknown. The use of antioxidants, such as alpha-tocopherol and beta-carotene, was associated with unpredictable off-target effects, such as increased lung and pancreas cancer in male smokers [5]. 6) Antioxidant vitamin supplementation has not reduced rates of cardiovascular events in any study [6]. As the authors acknowledge future studies will provide valuable data to establish public health recommendations on the use of polyphenols and PJ. For now other well established lifestyle interventions should be endorsed. These include a Mediterranean type diet [7], body weight control, smoking cessation and increased physical activity [8].

scholarly journals Rare Case Report on Emamect in Benzoate Poisoning in Buffaloes

2018 ◽  
Vol 3 (2) ◽  
pp. 1-2
Author(s):  
Sivajothi S
Keyword(s):  
Case Report ◽  
Rare Case ◽  
Macrocyclic Lactone ◽  
Atropine Sulfate ◽  
Vitamin Supplementation ◽  
Mixed Solution ◽  
Buffalo Calf ◽  
Emamectin Benzoate ◽  
Rare Case Report ◽  
History Of

Emamectin benzoate is a macrocyclic lactone which is commonly used as pest control in agriculture and indiscriminate use of these compounds causes toxicity in the livestock. Two buffaloes were reported to be had a history of acc idental ingestion of emamectin benzoate mixed solution and they showed disorientation, circling, incoordination, salivation, nasal discharges and shivering. Animals were treated with atropine sulfate, fluid therapy with vitamin supplementation and oral lax atives. Adult buffalo was recovered from the toxicity by the fifth day of therapy but buffalo calf was died by the second day of therapy.

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