scholarly journals A study on prevalence of diabetes mellitus among adult tuberculosis patients in tertiary health care centre, Hyderabad

Author(s):  
S.Bhavana Laxmi ◽  
Sri Harsha Kandikonda ◽  
Jyothi Lakshmi Naga Vemuri ◽  
R. L. Lakshman Rao

Background: Tuberculosis is a major public health problem and is among top ten causes of deaths worldwide. People with diabetes are three times at higher risk of getting infected with tuberculosis. Globally 10.4 million TB cases exists of them 10% are linked to diabetes. In India 13% of Tuberculosis cases were diabetic. DM has been reported to modify the clinical features of TB. The objectives were to study the prevalence of diabetes mellitus among adult tuberculosis patients registered in DOTS centre in tertiary health care centre, Hyderabad and to study the clinical profile of tuberculosis in study subjects.Methods: A cross sectional study was conducted in 4 DOTS centres under tertiary health care facility, Hyderabad. Sample size 200 was calculated using formula 4PQ/L2. Study subjects were registered adult tuberculosis patients attending DOTS centre and undergoing anti tuberculosis treatment. Data from study subjects was obtained by interview method using semi structured questionnaire consisting of socio-demographic parameters and clinical parameters.Results: Out of 200 patients, the prevalence of DM was found to be 18% (n=36). Increasing age (p<0.000), male sex (p=0.04), low BMI (p=0.02), family history of TB (p=0.017), Sputum positive severity (p=0.0008) are significantly associated with DM-TB comorbidity and clinical manifestations like bilateral involvement (p=0.151), multi lobes (p=0.243), other associated lung diseases (p=0.154), treatment category (p=0.8203) are not significantly associated with DM-TB comorbidity.Conclusions: Bidirectional screening of TB and DM will detect early and prevent complications of comorbiditiy.

2019 ◽  
Vol 20 (8) ◽  
pp. 658-664 ◽  
Author(s):  
Marco Di Paolo ◽  
Luigi Papi ◽  
Paolo Malacarne ◽  
Federica Gori ◽  
Emanuela Turillazzi

Background: Healthcare-associated infections (HCAIs) occur when patients receiving treatment in a health care setting develop an infection. They represent a major public health problem, requiring the integration of clinical medicine, pathology, epidemiology, laboratory sciences, and, finally, forensic medicine. Methods: The determination of cause of death is fundamental not only in the cases of presumed malpractice to ascertain the causal link with any negligent behavior both of health facilities and of individual professionals, but also for epidemiological purposes since it may help to know the global burden of HCAIs, that remains undetermined because of the difficulty of gathering reliable diagnostic data. A complete methodological approach, integrating clinical data by means of autopsy and histological and laboratory findings aiming to identify and demonstrate the host response to infectious insult, is mandatory in HCAIs related deaths. Results: Important tasks for forensic specialists in hospitals and health services centers are the promotion of transparency and open communication by health-care workers on the risk of HCAIs, thus facilitating patients’ engagement and the implementation of educational interventions for professionals aimed to improve their knowledge and adherence to prevention and control measures. Conclusion: HCAIs are a major problem for patient safety in every health-care facility and system around the world and their control and prevention represent a challenging priority for healthcare institution and workers committed to making healthcare safer. Clinicians are at the forefront in the war against HCAIs, however, also forensic pathologists have a remarkable role.


2017 ◽  
Vol 5 (4) ◽  
pp. 53-58
Author(s):  
Ogoudjobi OM ◽  
Sossa Jérôme C ◽  
Lokossou MSHS ◽  
Tshabu-Aguemon C. ◽  
Kérékou A. ◽  
...  

2019 ◽  
Vol 10 (2) ◽  
pp. 149-151
Author(s):  
Lature L H ◽  
◽  
S Anand ◽  
Lature Mahalaxmi L ◽  
◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Abaseen Khan Afghan ◽  
Masoom Kassi ◽  
Pashtoon Murtaza Kasi ◽  
Adil Ayub ◽  
Niamatullah Kakar ◽  
...  

Cutaneous leishmaniasis (CL) is a rising epidemic in Pakistan. It is a major public health problem in the country especially alongside regions bordering the neighboring Afghanistan and cities that have had the maximum influx of refugees. The purpose of our paper is to highlight the diverse clinical manifestations of the disease seen along with the geographic areas affected, where the hosts are particularly susceptible. This would also be helpful in presenting the broad spectrum of the disease for training of health care workers and help in surveillance of CL in the region. The increased clinical diversity and the spectrum of phenotypic manifestations noted underscore the fact that the diagnosis of CL should be not only considered when dealing with common skin lesions, but also highly suspected by dermatologists and even primary care physicians even when encountering uncommon pathologies. Hence, we would strongly advocate that since most of these patients present to local health care centers and hospitals, primary care practitioners and even lady health workers (LHWs) should be trained in identification of at least the common presentations of CL.


2020 ◽  
Vol 3 (1) ◽  
pp. 241-249
Author(s):  
OG Ogbeyi ◽  
L Luret ◽  
S Ogiri ◽  
T Aforlaranrami ◽  
SA Igbabul

Despite the availability of effective intervention programs over the years, tuberculosis remains a major global health problem. It causes ill-health among millions of people each year and ranks alongside the Human immunodeficiency virus (HIV) as a leading cause of death worldwide. The aim of this study is to assess the outcome of tuberculosis treatment in a Rural Primary Health Care Centre, Benue State, North Central Nigeria. A three-year retrospective study was employed to review 150 tuberculosis cases treated from January 2014 - December 2016. Data were analysed using Statistical Package for Social Sciences (SPSS) version 20 and presented as tables and charts. The relationship between independent and outcome variables were tested with Chi-square test and P-value was set at 0.05. Of the 150 Tuberculosis patients treated, 84(56.0%) were males while 66(44.0%) were females. More than two-thirds (77.3%) of the patients had pulmonary tuberculosis. The successful treatment rate was 60.0% (32.7% treatment completed and 27.3% cured). Over twelve percent defaulted, 10.7% were lost to follow up, 6.7% were transferred out and 0.7% died. In this study, the successful treatment outcome was lower than the National target .The relationship between the disease sites; HIV status, Cotrimoxazole prophylaxis and the treatment outcome were statistically significant. Directly Observed Treatment Short Course (DOTS) providers should address issue of hindrances to adherence to treatment in order to improve the treatment success rate.


2020 ◽  
Vol 3 (1) ◽  
pp. 241-249
Author(s):  
OG Ogbeyi ◽  
L Luret ◽  
S Ogiri ◽  
T Aforlaranrami ◽  
SA Igbabul

Despite the availability of effective intervention programs over the years, tuberculosis remains a major global health problem. It causes ill-health among millions of people each year and ranks alongside the Human immunodeficiency virus (HIV) as a leading cause of death worldwide. The aim of this study is to assess the outcome of tuberculosis treatment in a Rural Primary Health Care Centre, Benue State, North Central Nigeria. A three-year retrospective study was employed to review 150 tuberculosis cases treated from January 2014 - December 2016. Data were analysed using Statistical Package for Social Sciences (SPSS) version 20 and presented as tables and charts. The relationship between independent and outcome variables were tested with Chi-square test and P-value was set at 0.05. Of the 150 Tuberculosis patients treated, 84(56.0%) were males while 66(44.0%) were females. More than two-thirds (77.3%) of the patients had pulmonary tuberculosis. The successful treatment rate was 60.0% (32.7% treatment completed and 27.3% cured). Over twelve percent defaulted, 10.7% were lost to follow up, 6.7% were transferred out and 0.7% died. In this study, the successful treatment outcome was lower than the National target .The relationship between the disease sites; HIV status, Cotrimoxazole prophylaxis and the treatment outcome were statistically significant. Directly Observed Treatment Short Course (DOTS) providers should address issue of hindrances to adherence to treatment in order to improve the treatment success rate.


2019 ◽  
pp. 26-29
Author(s):  
Thi Ngoc Thuy Ha ◽  
Nu Phuong Anh Ton ◽  
Thi Minh Chau Ngo ◽  
Chi Cao Le

Background: The flagellate protist Trichomonas vaginalis is the causative agent of the most common non - viral sexually transmitted infection. T. vaginalis is a major health problem in the community. Symbiotic between T. vaginalis and M. hominis related to severe clinical manifestations of T. vaginalis infection and have been identified by many studies in the world but currently, there has not been studied in Vietnam. Objectives: To identify the rate of Trichomonas vaginalis infection in women visiting the Thua Thien Hue Reproductive Health Care Centre and the propotion of coinfection and symbiosis of T. vaginalis with M. hominis. Methodology: Cross-sectional and in-vitro study of vaginal discharge infected by T. vaginalis. Results: The rate of Trichomonas vaginalis infection in women visiting the Thua Thien Hue Reproductive Health Care Centre was 0.5%; the propotion of coinfection and symbiosis of T. vaginalis and M. hominis were 37.5% and 29.2% respectively. Conclusion: This is the first study in Vietnam recording the symbiosis between T. vaginalis and M. hominis by molecular techniques. Key words: Trichomonas vaginalis, Mycoplasma hominis, symbiosis


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