scholarly journals Nasomaxillary swellings: our experience at tertiary care hospital

2021 ◽  
Vol 7 (3) ◽  
pp. 469
Author(s):  
Mukesh Rawat ◽  
Archana Lall ◽  
Kavita Sachdeva
Keyword(s):  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Final Diagnosis ◽  
Inverted Papilloma ◽  
Nasal Endoscopy ◽  
Common Symptom ◽  
Fungal Sinusitis ◽  
Care Hospital ◽  
Malignant Lesions

<p class="abstract"><strong>Background:  </strong>A wide spectrum of lesions may present as nasomaxillary swellings ranges from benign to malignant lesions including fungal sinusitis and fibro vascular lesions example: JNA (Juvenile nasopharyngeal angiofibroma) and Inverted papilloma. Many Pathologies ranging from benign to malignant tumors may mimic a simple Nasomaxillary mass. It is diagnostic challenge to determine pathology behind it. A detailed clinical evaluation with nasal endoscopy and relevant pre-operative investigations including radiological imaging and histopathological examination is essential to reach up to final diagnosis. The aim of the study was to do clinicopathological evaluation of patients presenting with nasomaxillary swelling and correlation of clinical, radiological and Histopathological findings.</p><p class="abstract"><strong>Methods: </strong>This was a prospective observational study on 50 nasomaxillary swelling patients who are presented in the Department of ENT and Head and Neck Surgery of N.S.C.B. MCH Jabalpur, a tertiary care Hospital, between March 2018 to August 2019. A detailed history taking and clinical examination with nasal endoscopy and relevant preoperative investigations including CECT Nose and PNS and histopathological examination was done in all patients.</p><p class="abstract"><strong>Results: </strong>50 Nasomaxillary swelling patients were selected for this study. 30 patients were male and 20 were females. Ages of patients were varied from 12 years to 72 years. 23 patients (46%) were malignant and 27 (54%) were benign. Histopathological examination results shows benign lesions like JNA (6 cases), fungal sinusitis (6 cases), dermoid cyst (1 case), inverted papilloma (3 cases), sebaceous cyst (1 case), jaw lesions (10 cases), (odontogenic like radicular/ infected cyst, dentigerous cyst, cystic ameloblastoma and non-odontogenic like fibrous dysplasia) and malignant lesions like SCC (squamous cell carcinoma) (12 cases), spindle cell sarcoma (2 cases), undifferentiated carcinoma (3 cases), adenocarcinoma (3 cases), adenoid cystic carcinoma (1 case), Invasive pleomorphic sarcoma (1 case) and malignant melanoma (1 case). SCC was most common lesion f/b JNA and fungal sinusitis. Well differentiated SCC was most common histological type (10 out of 12 cases of SCC). Most common symptom was nasal obstruction (66% cases) f/b epistaxis (52% cases) but epitasis was most common symptom among malignant and JNA cases. In 6 cases (3 JNA, 1 inverted papilloma, 1 malignancy and 1 radicular cyst) radiological diagnosis were not correlated with histological findings.</p><p class="abstract"><strong>Conclusions: </strong>Most our cases were malignant nasomaxillary lesions followed by fungal sinusitis and JNA. Most patients presented in advanced stage of disease so rapidly evaluation including nasal endoscopy should be done. CECT scan is essential to determine tumors extent and bony lesions. All patients should undergo hisotopatholigical examination. The final diagnosis should be made on the basis of clinical, radiological and histopathological findings.</p>

A STUDY FOR EVALUATION OF CLINICAL, BIOCHEMICAL, TUMOR MARKERS AND RADIOLOGICALPARAMETERS IN PATIENTS OF OBSTRUCTIVE JAUNDICE

2021 ◽  
pp. 59-61
Author(s):  
Sangamesh S K ◽  
S R Ghosh ◽  
Debarshi Jana
Keyword(s):  
Obstructive Jaundice ◽  
Tumor Markers ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Final Diagnosis ◽  
Care Hospital ◽  
Malignant Obstructive Jaundice ◽  
Purposive Sampling ◽  
Radiological Parameters ◽  
Ca 19.9

Study was conducted in Command Hospital (Eastern Command) Kolkata - ATertiary Care Hospital with the following Aims and Objectives. Study and co relate clinical, biochemical, radiological parameters in obstructive jaundice. MATERIAL AND METHODS: Study was conducted in Command Hospital (Eastern Command) Kolkata - A tertiary care hospital. All adult patients who was diagnosed as case of obstructive jaundice based on clinical, radiological and pathological criteria. Study duration 3 Years. Purposive sampling, 50 in each group,100. RESULT AND ANALYSIS: BENIGN OBSTRUCTIVE JAUNDICE, 6(12.0%) patients had FEVER. In MALIGNANT OBSTRUCTIVE JAUNDICE, 2(4.0%) patients had FEVER. Association of FEVER vs FINAL DIAGNOSIS was not statistically signicant (p=0.1403). In BENIGN OBSTRUCTIVE JAUNDICE, 4(8.0%) patients had PRURITIS. In MALIGNANT OBSTRUCTIVE JAUNDICE, 37(74.0%) patients had PRURITIS. Association of PRURITIS vs FINAL DIAGNOSIS was statistically signicant (p<0.0001). CONCLUSION: AST and ALP were higher in malignant obstructive jaundice compared to benign obstructive jaundice which were statistically signicant. Mean GGT was higher in malignant obstructive jaundice compared to benign obstructive jaundice which was statistically signicant. It was found that mean CA 19.9 was higher in malignant obstructive jaundice compared to benign obstructive jaundice which was statistically signicant.

scholarly journals Clinical profile and changes in laboratory parameters among dengue patients at tertiary care hospital: an observational study

2019 ◽  
Vol 6 (5) ◽  
pp. 2276
Author(s):  
Pankaj Ashok Pande ◽  
Amit Jagdish Jogdande
Keyword(s):  
Observational Study ◽  
Clinical Features ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Lifestyle Changes ◽  
Common Symptom ◽  
Care Hospital ◽  
Rapid Urbanization ◽  
Dengue Patient ◽  
Laboratory Profile

Background: Globally the incidence of dengue has increased in the past three decades. It is predominantly found in the urban and semi-urban area however now it is spreading in rural areas also. In India the incidence of dengue has increased due to rapid urbanization, lifestyle changes and improper water storage practices. Hence this study was planned to study the clinical and laboratory profile of dengue patient as the number of dengue patients is on rise every year and there is varied presentation of clinical features in different parts of India.Methods: This observational study was carried out in tertiary care hospital. Confirmed cases of Dengue were included in the study. There cases were observed seven days. During this period their clinical and biochemical profile was recorded in pre structured and pre tested proforma. Data was compiled and analyzed by MS-Office (Excel) and SPSS-21.Results: In this study total 129 patients were enrolled. Out of total 91 were males and 38 were females. Laboratory profile of dengue patients suggested steep decline in total leucocytes count and platelet during first five days but started to increase by seventh day but platelets have not reached to its original normal value while TLC reverted to normal range. Fever and headache were most common symptom in our study.Conclusions: Clinical and laboratory profile of dengue patient changes with every new epidemic and different region in India. Clinical features like organomegaly are more common in paediatrics age group than adults. 

scholarly journals Correlation between nasal endoscopy and computed tomography in a tertiary care hospital

2019 ◽  
Vol 6 (1) ◽  
pp. 181
Author(s):  
Vinnakota Sriprakash ◽  
Shalini Singh Sisodia
Keyword(s):  
Computed Tomography ◽  
Chronic Rhinosinusitis ◽  
Paranasal Sinuses ◽  
Predictive Value ◽  
Tertiary Care ◽  
Nasal Endoscopy ◽  
Nasal Discharge ◽  
Common Symptom ◽  
Care Hospital ◽  
The Right

<p class="abstract"><strong>Background:</strong> Chronic rhinosinusitis is associated with morbidity and affects the quality of life of the affected persons and increases their treatment costs. Diagnosis is mainly by nasal endoscopy or by computed tomography which is considered to be the gold standard.</p><p class="abstract"><strong>Methods:</strong> Nasal endoscopy was done for all the patients under local anaesthesia. All the patients also underwent computed tomography and paranasal sinuses and the findings were scored according to Lund Mackay scoring system.  </p><p class="abstract"><strong>Results:</strong> The most common age group was 31-40 years and nasal discharge was the most common symptom seen in 82% of the patients. The paranasal sinuses that were involved were predominantly maxillary sinus in a total of 88% of the patients. 22% of the patients have sinusitis in the anterior ethmoid of the left nose and 20% on the right nose. Bilateral was seen in 22% of the cases. The sensitivity of nasal endoscopy over computed tomography was 95.6% while the specificity was 80%. The positive predictive value was 97.7% and the negative predictive value was 66.7%. The accuracy of the test was 94%.</p><p class="abstract"><strong>Conclusions:</strong> Nasal endoscopy is found to be as good as the computed tomography for the diagnosis of chronic rhinosinusitis and can be used on a regular basis for its detection among the patients. It not only lacks radiation but is also economically viable.</p>

scholarly journals Study of symptomatology and presentations of COVID-19 in pregnancy at a tertiary care hospital

2020 ◽  
Vol 9 (11) ◽  
pp. 4410
Author(s):  
Ankita M. Metkari ◽  
Tushar T. Palve
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Signs And Symptoms ◽  
Common Symptom ◽  
Care Hospital ◽  
Mild Disease ◽  
Moderate Disease ◽  
Different Populations ◽  
Clinical Records ◽  
In Pregnancy

Background: Objectives of this study were to study the incidence of SARS-CoV-19 positivity and the incidence of different signs and symptoms associated with COVID-19 in pregnancy and comparison of the same with studies done in different populations previously.Methods: In this retrospective study, antepartum and postpartum parameters were integrated into the clinical records and total 205 ANC and PNC SARS-CoV-19 positive patients were evaluated for the signs and symptoms of COVID -19 over 2 months.Results: In our study, of all patients tested SARS-CoV-19 positive only 14.65% were symptomatic and rest were incidentally tested positive on admission. Of the symptomatic patients 50% had breathlessness followed by fever (13.33%). 92% patients had mild disease; approximately 8% had moderate disease and 6 out of 205 patient needed ICU care.Conclusions: The present study shows that 85.35% SARS-CoV-19 positive ANC and PNC patients were asymptomatic while only 14.65% symptomatic with breathlessness being the most common symptom at our institute.

scholarly journals Cervical Cancer Screening On 1000 Healthy Asymptomatic Women Residing In Slum of Rajshahi City of Bangladesh

2017 ◽  
Vol 7 (1) ◽  
pp. 14-17
Author(s):  
Munira Ferdausi ◽  
Fatema Ashraf ◽  
Nourin Rahman ◽  
Zara Rahman ◽  
Fahima Mustanzid
Keyword(s):  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Cervical Screening ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Population ◽  
Asymptomatic Women ◽  
Rajshahi City

Background: Cervical carcinoma is an important cause of mortality among adult women.Objective: The purpose of the present study was to detect the pre-cancerous condition of cervix in women.Methodology: This cross sectional study was carried out in the OPD of a tertiary care hospital of Rajshahi City in Bangladesh during the year June 2010 to August 2011. Healthy asymptomatic women residing in slum of Rajshahi city with a marital age of 8 years and above were included as study population. VIA test was performed in all women. The VIA positive cases were invited for colposcopy and directed biopsies were obtained from women who were colposcopically positive.Result: A total number of 1000 women were studied. Among them 80(8%) women were VIA positive. These positive cases were also referred for colposcopy. Out of the 80 cases, 26 (32%) were colposcopically normal and 50(63%) were CIN-1 and 4(5%) women were CIN II. Directed biopsy was done among colposcopically positive group. Histopathological examination shows 44 (82%) were CIN-1 and 4(7%) were CIN- II and 6(11%) were chronic cervicities.Conclusion: Cervical screening of the slum area women shows an important number of women suffering from precancerous condition of which CIN-l is the most common.J Shaheed Suhrawardy Med Coll, 2015; 7(1):14-17

scholarly journals Clinicopathological study of gall bladder carcinoma with special reference to its management in a tertiary care hospital

2020 ◽  
Vol 7 (12) ◽  
pp. 4120
Author(s):  
Debmalya Saha ◽  
Saket Jha ◽  
Sukalyan Chhaule ◽  
Rabin Mandal ◽  
Anadi Acharya ◽  
...  
Keyword(s):  
Gall Bladder ◽  
Gallbladder Cancer ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Treatment Protocol ◽  
Rank Test ◽  
Common Symptom ◽  
Care Hospital ◽  
Female Ratio ◽  
Mortality And Morbidity

Background: Incidence of gallbladder carcinoma is increasing progressively among Indians and is regarded as a major cause of mortality and morbidity. In spite of this, limited studies have been conducted so far. Objective of the study was to know the prevalence, clinicopathological aspects, and prevalent treatment protocol of gall bladder cancer in a tertiary care hospital in Eastern India.Methods: 64 cases of histologically proven gallbladder cancer patients were studied. Patient characteristics were recorded using pretested proforma along with relevant investigations, and histopathology and treatment provided were recorded.Results: Our study reveals that gallbladder cancer has a prominent peak in the 7th decade of life with male: female ratio of 1:2.2. Most of the patients were having body mass index between 20.0 and 24.99, which is in sharp contrast to the available literatures. Pain is the most common symptom followed by constitutional symptoms. Majority of cases presented at advanced stage (64.1%) with significantly elevated CA19.9 level, and were managed with palliative chemotherapy.35.9% of our cases were respectable at the time of diagnosis, and extended cholecystectomy could be performed in 31.3%. Log rank test showed pattern of survival of the patients who were resected was significantly better than those of who were not resected.Conclusions: We know gallbladder cancer is a disease with very few patients amenable to surgery at the time of presentation. Thus, instead of retrospectively analyzing individual institutional data, high volume institutions with the necessary expertise for treating gallbladder cancer should collaborate with a view of generating strong evidence-based surgical guidelines.

scholarly journals Knowledge, attitude and practice regarding tuberculosis among the patients attending a tertiary care hospital in Maharashtra, India: a cross sectional study

2019 ◽  
Vol 6 (2) ◽  
pp. 371
Author(s):  
Nilesh S. Sonawane ◽  
Chaitanya R. Patil
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Female Ratio ◽  
Attitude And Practice ◽  
Knowledge Attitude And Practice

Background: Tuberculosis is major public health problem especially in the low and middle income countries like India. We conducted a study to assess the knowledge, attitude and practice related to tuberculosis among the patients attending our tertiary care institute.Methods: A cross sectional study was conducted in a tertiary care hospital on the patients attending OPD of tertiary care hospital in Maharashtra. The patients with debilitating illness or bed bound patients and those diagnosed and cured of tuberculosis or were on treatment of tuberculosis were excluded from the study. A pretested and designed questionnaire was used to assess the knowledge, attitude and practice about the cause, clinical features and treatment of tuberculosis.Results: The mean age of the study subjects was 43.34±11.23 years with male: female ratio of 1.45. About 16.67% of the subjects stated that cause of TB is bacteria, 51.33% reported that cough was the most common symptom, 58.67% believed that it spreads from person to person and among the people who said it spreads 58.67% said that it can be preventable.Conclusions: About 1/5th of the study subjects expressed the cause of TB is bacteria or germs, and more than ½ believed that TB spreads from person to person. About 2/3rd of the patients felt that TB was a very serious disease; more than ½ of them expressed fear if they were diagnosed with TB but more than ½ of them also expressed rejection if they have a TB patient as a closed one.

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