scholarly journals Topical corticosteroid abuse on face: a clinical study of 100 patients

Author(s):  
Pooja Bains

<p class="abstract"><strong>Background:</strong> Prolonged and uninterrupted use of topical corticosteroids on face is globally prevalant and this misuse has reached monstrous proportion in India. The topical corticosteroid abuse leads to various local adverse effects on face which are difficult to treat. The aim of this study was to ascertain the magnitude, demographics, cause and adverse effects of TC abuse on the face in the dermatology out-patient department.</p><p class="abstract"><strong>Methods:</strong> A total of 100 patients with history of topical corticosteroid abuse on face for a minimum period of one month were enrolled in this study.<strong></strong></p><p class="abstract"><strong>Results:</strong> In our study, majority of the patients were females (76%) and the most common age group was 21-30 years with 49% patients. The duration of application was &lt;6 months (45%) in majority of patients. Most common topical corticosteroids abused were betamethasone valerate in 49% and clobetasol propionate in 40% cases.</p><strong>Conclusions:</strong> Topical corticosteroid abuse on face is quite common with varied presentation. There is need to take urgent remedial steps and increase awareness about this problem in general population.

2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Shristi Shrestha ◽  
Smita Joshi ◽  
Sajana Bhandari

Introduction: Topical corticosteroids misuse has become one of the burning issues in many countries across the globe. They are known to cause a myriad of adverse effects which include local effects commonly and systemic effects rarely. In dermatology practice, one of the common problems we see these days are steroid-induced and steroid aggravated dermatoses. So, this study was done to find the prevalence of misuse of topical corticosteroid among dermatology outpatients. Methods: A descriptive cross-sectional study was done in the outpatient department of dermatology at atertiary care hospital for 18 months. Ethical clearance was obtained from the Institutional Review Committee of NMCTH (Reference no. 029-076/077). Convenient sampling was done. Statistical Package for the Social Sciences (SPSS) version 16 was used to tabulate the data and analyze the results. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data. Results: Out of 19464 patients, 614 (3.15%) (2.91%-3.39% at 95% Confidence Interval) gave a history of applying steroid containing creams. Among them, 220 (35.8%) belonged to the age group 21-30 years. Dermatophytoses were the skin disease where TCS was most commonly misused followed by melasma in 425 (69.2%) and 115 (18.7%) respectively. Beclomethasone was the steroid preparation that was misused in the maximum number of patients in 271 (44.1%). Some form of adverse effects was seen in 554 (88.6%) patients. Conclusions: Non-prescription sale of topical corticosteroids is the major cause of topical corticosteroids abuse in Nepal. Creating awareness among the prescribers as well as the patients is the current need.


Author(s):  
Dayanand Raikar ◽  
Mohammed Waseem Javed ◽  
Anant Arunrao Takalkar

<p class="abstract"><strong>Background:</strong> Facial pigmentary disorders are a group of heterogenous entities, sharing a common clinical feature of altered pigmentation of the face and thus easily visible cosmetic disfigurement. Although the increased melanin provides protection from harmful effects of UV radiation, including photodamage and skin cancers, it also makes darkly pigmented skin more vulnerable to post-inflammatory dyspigmentation. The importance of these disorders is growing, as they form the major percentage of dermatology consultations. The objective of the study was to assess the clinical profile of patients with facial hyperpigmentation.</p><p class="abstract"><strong>Methods:</strong> The present cross-sectional hospital based observational study was conducted at Dermatology Department of during the period of June 2017 to December 2017 including patients with diagnosis of facial hyperpigmentation. Data analysed with SPSS 24 version.<strong></strong></p><p class="abstract"><strong>Results:</strong> 29% were from 21 to 30 years age group followed by 25% from 31 to 40 years age group. Mean age of the study population was 28.4±11.8 years. 76% were female patients. Commonly observed facial hyperpigmentation type was melasma in our study i.e. 46%. It is followed by post inflammatory hyperpigmentation (PIH) in 16% and ephilides in 8%. Rehl's melanosis and drug induced melanosis was seen in 7% each of the patients. Ephilides, Rehl's melanosis and drug induced was seen in 7% each of the patients. Family history of pigmentaory disorder was found in melasma, PIH and ephilides in our study.</p><p class="abstract"><strong>Conclusions:</strong> Commonly reported age group was 20-40 with female preponderance. Commonly observed facial hyperpigmentation type was melasma (46%), PIH (16%) and ephilides (8%).</p>


2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
F. A. Sendrasoa ◽  
I. M. Ranaivo ◽  
M. Andrianarison ◽  
O. Raharolahy ◽  
N. H. Razanakoto ◽  
...  

This cross-sectional study was conducted in Antananarivo, Madagascar, from June to September 2012. We aim to evaluate the misuse of TC on the face for cosmetic purpose and the adverse effects due to its application. A questionnaire-based analysis was done among females who use topical corticosteroids on the face for cosmetic purpose. Of the 770 women questioned, 384 (49,8%) used topical corticosteroids for cosmetic purpose whose mean age was 38 years (range 16–73 years). Two hundred and sixty-one females (68%) used TC combined with handcrafted cosmetics, and 123 (32%) used TC alone. “Pandalao,” which contains salicylic acid, peppermint oil, lanolin, powder of Juanes de Vigo (mercury powder), and Vaseline, is the most handcrafted cosmetic combined with TC in our study (used by 29,4% respondents). Only one (0,26%) had obtained the TC by physician’s prescription, 234 (61%) from cosmetic retailers, 92 (23%) directly from local pharmacies, 49 (12%) from beauticians, and 15 (4%) from unspecified sources. Lightening of skin color was the main reason for using TC in 44,8% of respondents in the absence of any primary dermatosis. Pigmentation disorders (63,2%) and cutaneous atrophy (52,1%) were the most adverse effects noted.


2017 ◽  
Vol 62 (6) ◽  
pp. 567 ◽  
Author(s):  
LalitKumar Gupta ◽  
Soniya Meena ◽  
AshokKumar Khare ◽  
Manisha Balai ◽  
Asit Mittal ◽  
...  

2019 ◽  
Vol 17 (1) ◽  
pp. 73-75
Author(s):  
Mohan Bhusal ◽  
Eliz Aryal ◽  
Sabina Bhattarai ◽  
Sanju Babu Shrestha ◽  
Alark Rajouria

Corticosteroids are over the counter and cheaper drugs available in every medical stores in Nepal. Iatrogenic Cushing syndrome due to topical steroids application is a very rare phenomenon in adults.A 32 year female from Janakpur presented with complaints of swelling of face, weight gain, excessive facial hair and fatigue since two years that gradually increased over last one year. She had a past medical history of on and off application of multiple potent topical corticosteroids for disseminated Tinea infection. She was obese with moon facies, buffalo hump and multiple striae over her abdomen. Her blood pressure was raised and her blood sugar was in pre-diabetic range. Laboratory studies were consistent with iatrogenic Cushing syndrome. Patient recovered after discontinuation of topical corticosteroids and treatment with antifungals.Although iatrogenic Cushing syndrome following application of topical corticosteroid is a rare phenomenon in adults, this can happen in a setup like ours where corticosteroids are prescribed as over the counters and patients have very little knowledge about their use. Therefore, we emphasize that patients and pharmacist should be well educated about the consequences of their prolong application and their side effects


2021 ◽  
pp. 902-905
Author(s):  
Hamna Azhar ◽  
Ambreen Tauseef ◽  
Tahir Usman ◽  
Yousra Azhar ◽  
Momna Ahmed ◽  
...  

Aim: To determine the prevalence, attitude, and knowledge of self-medication of general population for the prevention of coronavirus during the COVID 19 pandemic. Place and duration of the study: Major studies of Punjab during 2020. Methodology: A self-generated questionnaire was distributed online amongst the general population of Punjab excluding the people using medication for any other chronic medical disorder. The study included the general public including the age group from 16-60 years. Results: Among 290 participants, 33.7% were males and 66.3% were female. Based on the data obtained 53% used medication without a doctor’s prescription (self- medication) while 46.7% took the medication with a doctor’s prescription. Those with the habit of self-medication relied on both allopathic and herbal medications due to various reasons, the most frequent reason found was unavailability of doctors (27.8%). The most frequently used self-medicated drugs were pain killers, Hydroxychloroquinone, Azithromycin and Ivermectin to prevent from this deadly virus (p-value=0.000).Adverse effects reported after self-medications are statistically non-significant. Conclusion It is concluded that majority of the general population of Punjab are in the habit of self-medicating themselves because of difficulty in approaching physicians and the most commonly self-medicated drug with or without symptoms was found to be tablet Azithromycin as a preventive measure during this pandemic. Keywords: COVID-19, self-medication, adverse effects


Author(s):  
Aliza Zaidi ◽  
Kshitij Saxena ◽  
Ven R. Koti ◽  
Anukriti Singh ◽  
Ayesha Khalid ◽  
...  

<p class="abstract"><strong>Background: </strong>Steroids are a wide range of chemical molecules that have varying physiological effects. Corticosteroids own anti-inflammatory and immunosuppressive effects. They also have anti-proliferative effects on keratinocytes. The present study was undertaken to study the clinical aspects of the use of topical corticosteroids leading to adverse effects and to know the source of information leading to its abuse.</p><p class="abstract"><strong>Methods: </strong>A cross-sectional observational study was carried out on cutaneous adverse effects of TC attending the dermatology outpatient department of Era’s Lucknow medical college and hospital between December 2018 and November 2020. The patients who applied TC for more than 1 month were taken into account. Patients who had cutaneous adverse effects suggestive of TC without details of agents were excluded.</p><p class="abstract"><strong>Results:</strong> Present study explored the patterns of use of topical corticosteroid, and its associated adverse effects in a total of 380 patients (aged 3 to 71 years; mean age 27.33±11.78 years; 52.9% males). Itching (72.4%), burning skin (64.5%) and skin color change (62.4%) were the three most common presenting complaints. Dermatophytoses (66.6%), acne (17.4%) and skin lightening (6.3%) were the three most common indications for use of topical corticosteroids.</p><p class="abstract"><strong>Conclusions:</strong> The present study showed that the practice of using non-dermatologist prescribed topical corticosteroid use is highly prevalent and is associated with a high burden of adverse effects. To prevent this there is a need to spread awareness regarding harms associated with abuse of non-dermatologist prescribed topical corticosteroid use.</p>


Author(s):  
Abhay Kumar ◽  
Siddhartha Singh ◽  
Shivani Sinha ◽  
Abhishek Kumar ◽  
Santosh Kumar Nayan ◽  
...  

Background: Definitive treatment and vaccination are basic necessity to bring down the burden of COVID-19 disease. Due to rapid development of vaccine against COVID-19, associated anxiety and mistrust raises hesitancy for vaccination. We aim to study about the mindset of COVID-19 vaccination among health care employees (HCE) and general population at tertiary care hospital in north east India.Methods: This was a cross sectional and observational study; questionnaires were distributed among 200 HCE and 400 general populations visiting at different OPD regarding their mindset for vaccination. Questionnaires consisted of parameter such as history of previous COVID-19 infection or hospitalization, co-morbidities, job status during pandemic and educational qualification and contained specific questions for causes of vaccine hesitancy.Results: In the survey participants from general population were more hesitant for vaccination as compared to HCE (p<0.001). Most common cause for hesitancy among HCE was pregnancy/lactation followed by concern regarding adverse effects. Doubted efficiency and adverse effects were leading concerns (67%) for vaccine hesitancy among general population. Past history of infection or hospitalization due to COVID-19 did not affect the attitude for getting vaccinated (p>0.05). Among general population, 25% had their job affected during pandemic of which 78% were in favour of vaccination.Conclusions: Increased awareness and high risk of getting infected with COVID-19 makes HCE less hesitant for vaccination. It is important to increase awareness among the general population to bring down the concerns regarding adverse effect and potency of vaccine to reduce the hesitancy for vaccination.


2021 ◽  
Vol 9 (10) ◽  
pp. 2559-2566
Author(s):  
Meghavati M Awati ◽  
Raosaheb A Deshmukh ◽  
Renuka. M. Tenahalli ◽  
Jyothi Alias Jyotsa. P. Bargi P. Bargi ◽  
Sachin. S. Bagali

Yavanapidika is one among the Kshudra roga (minor disorder) 1explained in Classical texts. However, Sushruta has described this disease under the name of Mukhadushika2. Kapha, Vata & Rakta are considered as causative factors of Mukhdushika. Pidika (eruptions), Saruja(pain), Ghana (thick), Medagarbha (fat in eruption) are considered clinical features as mentioned in Samhitas. Yavana Pidaka can be correlated with Acne vulgaris. Acne is the most common skin problem which commonly affects Teenagers. According to the global burden of disease study, Acne Vulgaris affects about 85% of the age group of 12-25 years, Acne consistently represents the top three most prevalent skin conditions in the general population as found in large studies3. In this context, Dhanyakadi Lepa4 is applied externally as Bahirparimarjana Chikitsa in the form of lepa and Chandana Churna (Santalum album, Linn)5 with Madhu (honey)6 is used internally as Anthaparimarjana chikitsa on Yavanapidaka. Thirty patients suffering from Yavanapidika were randomly selected and the above-mentioned treatment was administeredfor thirty days. It is concluded that Dhanyakadi Lepa as Bahir parimarjana chikitsa and Chandana Churna and Madhu as Anthaparimarjana Chikitsa are effective in the treatment of Yavanapidaka. Keywords: Yavanapidika, Mukhadushika, Kshudra rogas, Acne vulgaris, Dhanyakadi lepa, Chandana churna, Madhu.


Sign in / Sign up

Export Citation Format

Share Document