scholarly journals Histopathological spectrum of vulvar lesions on a remote Indian Island

2021 ◽  
Vol 6 (3) ◽  
pp. 153-159
Author(s):  
Chitrawati Bal Gargade ◽  
Archana Hemant Deshpande ◽  
Seetu Palo
Keyword(s):  
Clinical Presentation ◽  
Wide Spectrum ◽  
Benign Neoplasms ◽  
Benign Lesions ◽  
Duct Cyst ◽  
Neoplastic Lesion ◽  
Number Of Patients ◽  
Histopathologic Diagnosis ◽  
Neoplastic Lesions ◽  
Malignant Lesions

A wide spectrum of normal, benign, premalignant, and malignant lesions may occur on the vulva. Symptoms of vulvar disorders may be non-specific. Empiric treatment of vulvovaginal symptoms is common but usually not helpful. Though the varied clinical presentation and diverse histopathological spectrum of vulvar lesions have amazed Pathologists, only a few studies have been reported in the literature. The present study consists of a histopathological spectrum of vulvar lesions. 1.To evaluate the histopathological spectrum of vulvar lesions. 2. To compare the incidences of non-neoplastic and neoplastic lesions of the vulva. Present study includes all types of vulvar lesion specimens received in the Department of pathology over a period of four years.    All thirty-nine vulvar biopsies received in the Department of Pathology were studied for histomorphologic features. The lesions were categorized as non-neoplastic, neoplastic. The neoplastic ones were further divided into benign, malignant, and premalignant. The age of the women ranged from 15 to 69 years (mean 36.18±12.71) with the maximum number of patients between 30 to 40 years of age. Non neoplastic lesions were more common (22; 56.4%) than the (17; 43.6%) neoplastic lesions. There were 15(38.5%) benign lesions while 2 cases (5.13%) were malignant. Among the non-neoplastic lesions, Bartholin's duct cyst was the most common histopathologic diagnosis (35.9%). The fibroepithelial polyp was the most common benign neoplastic lesion constituting 15.3%.  In the present study nonneoplastic lesions were more common than neoplastic lesions. Among the neoplastic lesions, benign neoplasms were more frequent than malignant lesions.

scholarly journals Epidermoid Cysts – A Wide Spectrum of Clinical Presentation and Successful Treatment by Surgery: A Retrospective 10-Year Analysis and Literature Review

2018 ◽  
Vol 6 (1) ◽  
pp. 28-30 ◽  
Author(s):  
Uwe Wollina ◽  
Dana Langner ◽  
Georgi Tchernev ◽  
Katlein França ◽  
Torello Lotti
Keyword(s):  
Literature Review ◽  
Clinical Presentation ◽  
Wide Spectrum ◽  
Genetic Disorders ◽  
Lowe Syndrome ◽  
Benign Lesions ◽  
Cutaneous Lesions ◽  
Internal Organs ◽  
Epidermoid Cysts ◽  
Multiple Cysts

Epidermoid cysts are common benign lesions of hair-bearing, and less often glabrous skin. They can also occur in oral mucosa and internal organs. In case of cutaneous lesions, an epidermal punctum is a clinical diagnostic hallmark. The clinical presentation is variable leading to some differential diagnoses. Diagnosis of epidermoid cysts needs histopathological confirmation – not only of the potential of malignant transformation. The treatment of choice is surgery. We report a retrospective analysis of 2159 epidermoid cysts treated surgically. Most of the cases can be performed under local anaesthesia. The complication rate of 2.2% is low. To avoid relapses, the cyst wall has to be removed completely. Rare genetic disorders with multiple cysts are Gardner and Lowe syndrome.

scholarly journals Pattern of salivary gland tumors in Manipur, India: A 10 year study

2013 ◽  
Vol 02 (04) ◽  
pp. 250-253 ◽  
Author(s):  
Rajesh Singh Laishram ◽  
Arun Kumar K. ◽  
Gayatri Devi Pukhrambam ◽  
Sharmila Laishram ◽  
Kaushik Debnath
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Salivary Gland Tumors ◽  
Neoplastic Lesion ◽  
Chronic Sialadenitis ◽  
Significant Difference ◽  
North Eastern ◽  
Neoplastic Lesions ◽  
Malignant Group ◽  
Malignant Lesions

Abstract Background: Salivary gland lesions, especially the neoplastic lesions constitute a highly heterogeneous histopathologic group. Several studies have reported a significant difference in the global distribution of salivary gland tumors, but no formal study has been carried out in this part of the globe. Objectives: To document the pattern of various salivary gland tumors in Manipur, a state in North Eastern India. Materials and Methods: This is a 10 years (2002-2011) retrospective study of all salivary gland specimens received at our referral teaching hospital in Manipur, India. All the histopathology slides of salivary gland specimens during the study period were reviewed and clinical details were obtained from the archives. Restaining of slides and fresh sections of tissue blocks were performed whenever required. Data thus collected were analyzed. Results: A total of 104 cases of salivary gland lesions were studied during the study period. Age ranged from 5 years to 78 years with an overall slight female preponderance (M:F = 1:1.08). Parotid (56.65%) was the commonest gland involved followed by submandibular gland (31.73%). Neoplastic lesions comprised of 78 (75%) cases and non-neoplastic lesions constituted 25% (26 cases). Among the neoplastic lesions, benign lesions (53.85%) predominated over malignant lesions (21.15%). Pleomorphic adenoma was the commonest benign neoplastic lesion and mucoepidermoid carcinoma was the commonest malignant tumor. Chronic sialadenitis was the predominant lesion in the non-neoplastic group. Conclusion: The principal site for salivary gland tumors was the parotid gland and pleomorphic adenoma outnumbered all the other tumors. Females are more affected in the malignant group.

Imaging of Pediatric Soft Tissue Tumors and Tumor-like Conditions

2021 ◽  
Vol 25 (01) ◽  
pp. 039-056
Author(s):  
Sinan Al-Qassab ◽  
Radhesh Lalam ◽  
Rajesh Botchu ◽  
Alberto Bazzocchi
Keyword(s):  
Soft Tissue ◽  
Clinical Presentation ◽  
Soft Tissue Tumors ◽  
Practical Approach ◽  
Differential Diagnoses ◽  
Imaging Feature ◽  
Anatomical Location ◽  
Imaging Features ◽  
Neoplastic Lesions ◽  
Malignant Lesions

AbstractLumps and bumps are frequently seen in children, and the vast majority are a result of trauma, infection, or inflammation. True soft tissue neoplastic lesions are rare; however, their wide and complex classifications make these lesions challenging to manage. Imaging features are usually nonspecific, and a reasonable list of differential diagnoses can be generated following consideration of the clinical presentation, age, and anatomical location of the lesion. In this article, we offer a practical approach to diagnosing such lesions by discussing the most common three benign and malignant lesions in different anatomical regions stratified by age with emphasis on certain features that might aid in the diagnosis such as depth, multiplicity, calcification, or other specific imaging feature.

scholarly journals Uterine Cervix-Benign Histomorphological Spectrum

2018 ◽  
Vol 1 (1) ◽  
pp. 1-4
Author(s):  
Sunila Basnet ◽  
Shiva Raj KC ◽  
Geetika KC
Keyword(s):  
Biopsy Specimen ◽  
Target Organ ◽  
Benign Neoplasms ◽  
Benign Lesions ◽  
Cervical Lesions ◽  
Medical College ◽  
Cervical Biopsy ◽  
Inappropriate Treatment ◽  
Neoplastic Lesions ◽  
Chronic Cervicitis

Introduction: Non neoplastic lesions of cervix form a wide variety of lesions in the cervical biopsy specimen or hysterectomy specimens. Chronic cervicitis is the commonest finding; but can be associated with other underlying pathologies. In our study we aim to study and categorize the morphology of non neoplastic lesions of cervix in cervical biopsy specimen or hysterectomy specimens into inflammatory, reparative or reactive lesions, glandular hyperplasia, metaplasia and ectopies and benign neoplasm.Materials and Methods: This is a retrospective study that consisted of 520 slides retrieved from the records of department of histopathology KIST medical college. Whenever required block were retrieved and recut sections were made. All the benign lesions were included in the study.Results: The commonest lesions diagnosed were inflammatory, reparative or reactive changes 513 (98.6%) cases, followed by metaplastic changes 311 (59.8%) and glandular hyperplasia in 44 cases (8.4%). Benign neoplasms were seen in 33(6.3%) cases.Conclusions: Cervix is a target organ for varieties of neoplastic and non neoplastic diseases. There are many benign mimics of malignant cervical lesions. It may be difficult to interpret adequately in a small biopsy specimen however it is necessary to distinguish between these benign lesions and their mimics to prevent unnecessary inappropriate treatment to the patient.Nepalese Medical Journal. vol.1, No. 1, 2018, Page : 1-4

Clinical Presentation and Outcomes of Surgery for Upper Extremity Lipomas

2021 ◽  
Vol 23 (6) ◽  
pp. 393-400
Author(s):  
Andrzej Żyluk
Keyword(s):  
Upper Extremity ◽  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Clinical Manifestations ◽  
Benign Neoplasms ◽  
Fat Tissue ◽  
Benign Lesions ◽  
Telephone Interviews ◽  
Postoperative Scar

Background. Lipomas are benign neoplasms arising from fat tissue, with an incidence in the upper extremity of 1%-3,8%. There is scarce literature on the outcomes of the treatment of lipomas in this region. The objective of this study was to assess clinical manifestations and outcomes of surgery for upper extremity lipomas. Material and methods. The sample comprised 40 patients, including 26 women (65%) and 14 men (35%), at a mean age of 37 years, with lipomas located in the upper limbs. Treatment outcomes were assessed at a mean of 4.2 years after surgery in 27 patients from this group. Results. Most of the tumours (29 cases, 73%) were located in the forearm and arm, with 11 patients (27%) presenting with lipomas of the metacarpus and wrist. In 35 patients (87%), lesions were located superficially, within subcutaneous tissue, whereas in 5 (13%) they were located more deeply, in the metacarpus and in the forearm muscles. The follow-up assessment was conducted as telephone interviews in 27 patients. No recurrence was noted. Seven patients (26%) complained of mild tenderness of the postoperative scar. Conclusions. 1. Lipomas are moderately frequent benign lesions occurring in the upper limb. 2. Surgical treat­ment is effective and the recurrence rate is very low.

scholarly journals Diagnosis of upper gastrointestinal lesions by endoscopy and its correlation with histopathology

2020 ◽  
Vol 8 (2) ◽  
pp. 100-105
Author(s):  
Santhi Kiran D. ◽  
Nagarjuna Kumar Y. R.
Keyword(s):  
Gastrointestinal Tract ◽  
Diagnostic Procedure ◽  
Histopathological Examination ◽  
Wide Spectrum ◽  
Age Groups ◽  
Gastric Cavity ◽  
Gastrointestinal Lesions ◽  
Neoplastic Lesions ◽  
Malignant Lesions ◽  
Upper Gastrointestinal

Background: A wide spectrum of lesions can be encountered in the upper gastrointestinal tract (GIT) especially the stomach or the gastric cavity. Endoscopy forms a crucial diagnostic procedure; it gives good diagnostic results in non-neoplastic lesions, endoscopy with biopsy is usually done in neoplastic lesions where the differentiation of benign and malignant lesions cannot be made always. Materials and Methods: This is a retrospective cum prospective study and the duration of this study was 4 yearsfrom January 2015 to December 2019 and the total number of endoscopic procedures performed was 3978. All patients with symptoms pertaining to the upper GIT where Upper Gastro-Intestinal Endoscopy (UGI Endoscopy) is useful in diagnosis were included in this study. All age groups and both the sexes were included. Biopsy was taken wherever there was an indication. Results: In this study, a total of 3978 endoscopies were done, out of which 2689 patients were males (67.6%) and 1289 were females (32.4%), youngest patient age in this study was 13 years and the oldest was 79 years. Most of the lesions were located in the gastric cavity (48% - 1909 cases), followed by esophagus (34%-1353 cases) and least among the three in the duodenum (18%- 716 cases). Out of the 3978 lesions, 134 cases were diagnosed as carcinoma on endoscopy and they were confirmed by histopathological examination. Conclusion: Endoscopy plays a very important role in the diagnosis of upper GIT lesions and it is incomplete without histopathological examination of biopsied tissue in cases of neoplastic lesions

scholarly journals Histopathological Spectrum of Non-neoplastic and Neoplastic Lesions of Urinary Bladder

2021 ◽  
Vol 4 (2) ◽  
pp. 473-477
Author(s):  
Manisha Shrestha ◽  
Dipti Gautam ◽  
Prakriti Shah ◽  
Prateek Krishna Shrestha
Keyword(s):  
Urinary Bladder ◽  
Urothelial Carcinoma ◽  
Wide Spectrum ◽  
Detrusor Muscle ◽  
Male Predominance ◽  
Neoplastic Lesion ◽  
Neoplastic Lesions ◽  
Histopathologic Evaluation ◽  
Hematoxylin And Eosin ◽  
A Site

Introduction: Urinary bladder is a site of various non-neoplastic and neoplastic lesions, both of which can present with hematuria. Cystoscopy allows for direct visualization of the bladder mucosa and also obtaining tissue for histopathologic evaluation. The most common non-neoplastic and neoplastic lesion of the urinary bladder is non-specific cystitis and urothelial carcinoma respectively. Materials and methods: This study is a 4-year retrospective study conducted in the Department of Pathology at Patan Hospital, Nepal. All cases from the urinary bladder i.e., both cystoscopic and cystectomy samples were included in the study. Hematoxylin and eosin-stained slides were re-evaluated whenever required. Results: A total of 145 cases were included which consisted of 17 cystectomy specimens and 128 cystoscopic biopsies. There was a male predominance. The non-neoplastic and neoplastic cases consisted of 32% and 68% respectively. Chronic non-specific cystitis and high-grade infiltrating urothelial carcinoma were the most common non-neoplastic and neoplastic lesions respectively. 56.1% of cystoscopic biopsies had the presence of detrusor muscle with 21.7% showing its invasion. Conclusions: Urinary bladder lesions have a wide spectrum ranging from non-neoplastic to neoplastic conditions. The presence of detrusor muscle in a cystoscopic biopsy, and its evaluation for invasion helps in diagnosis and further planning of patient management.

scholarly journals Clinical Presentation of Cholesteatoma- A Study of 50 Cases

2017 ◽  
Vol 13 (1) ◽  
pp. 66-70
Author(s):  
Md Ahsanuzzaman Khan ◽  
AKM Asaduzzaman ◽  
Md Tauhidul Islam ◽  
Bashir Ahmed ◽  
Mohammad Kamal Hossain ◽  
...  
Keyword(s):  
Middle Ear ◽  
Rural Areas ◽  
Clinical Presentation ◽  
Armed Forces ◽  
Petrous Apex ◽  
Female Ratio ◽  
Conductive Deafness ◽  
Neoplastic Lesion ◽  
Number Of Patients ◽  
Intracranial Complications

Introduction: Cholesteatoma is an abnormal accumulation of keratin-producing squamous epithelium in the middle ear, epitympanum, mastoid or petrous apex. It is a threedimensional epidermoid structure exhibiting independent growth, replacing middle ear mucosa, resorbing and replacing underlying bone. Although it is not a neoplastic lesion, it can be insidious and potentially dangerous to the patient. Objective: To find out the socio-demographic pattern, clinical presentation and complication of cholesteatoma. Materials and Methods: This prospective study of 50 cases was done in the Department of Otolaryngology and Head-Neck surgery, CMH, Dhaka adopting simple random sampling technique from July 2008 to Dec 2009. Data were collected by personal interview and clinical examination in a pre-designed data sheet and were analyzed by SPSS 20. Results: In this study, the highest number of patients (44%) was in the age group 11-20 years with a mean age of 17.2 years. Male were more affected (70%) and the male to female ratio was 2.33:1. Commonest symptom was otorrhoea (100%), followed by hearing impairment (80%), otalgia (16%), postauricular painful swelling (12%) and postauricular discharging sinus (10%). Extracranial complications were in 26% and intracranial complications in 12% of patients in this series. Abscess (temporal lobe + extra dural) were found in 02 cases (10%) by CT scan. A maximum number of patients had moderate conductive deafness (74.47%) followed by mild conductive deafness (19.15%) and only a few with severely mixed deafness (6.38%). Conclusion: Clinical presentation of cholesteatoma in this study was discharge and deafness. The discharge was thick purulent foul smelling, scanty, occasionally blood-stained. Grave intracranial complications in children developed because of illiteracy, poverty, lack of awareness and medical facilities mostly in the rural areas. So early diagnosis and prompt treatment was a necessity. Journal of Armed Forces Medical College Bangladesh Vol.13(1) 2017: 66-70

scholarly journals Clinicopathological Profile of Sino-nasal Masses at a Tertiary Care Hospital: A Descriptive Study

2021 ◽  
Vol 29 (2) ◽  
pp. 133-139
Author(s):  
Nitin Deosthale ◽  
Priyal Patil ◽  
Sonali Khadakkar ◽  
Pavani Garikapati ◽  
Kanchan Dhote ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Careful Examination ◽  
Care Hospital ◽  
Male Predominance ◽  
Neoplastic Lesion ◽  
Number Of Patients

Introduction The Sino-nasal mass is a common clinical entity. Although it has varied aetiology ranging from non-neoplastic to neoplastic, clinical presentation is overlapping that poses diagnostic dilemma. Objective of the study was to study the clinical profile of Sino-nasal masses in terms of demographic profile, clinical presentation and clinicopathological diagnosis. Materials and Methods A descriptive study was carried out at tertiary care hospital for 2 years. Clinically diagnosed cases of sino-nasal masses were included in the study. Previously treated cases, congenital lesions were excluded. Provisional diagnosis was made based on clinical and radiological evaluation. Diagnosis on histopathological examination was considered as definitive. Results Total of 75 patients were included in the study. Demographic data showed slight male predominance (M:F= 1.08:1), with most patients from age group 31-40 years (26.67%). Nasal obstruction was the most common presenting symptom. The number of patients with non-neoplastic lesion was 48; 17 patients had neoplastic benign lesions while 6 patients had neoplastic malignant lesions. Conclusion Large number of patients presents with trivial symptoms but need careful examination and appropriate diagnosis. Inflammatory lesions outnumbered neoplastic lesions in our study. Clinical suspicion and appropriate investigations can guide in timely intervention and management of these patients reducing the morbidity and mortality in these patients.

scholarly journals A clinicopathological study and management of tumor and tumor like lesions of larynx

2021 ◽  
Vol 7 (12) ◽  
pp. 1906
Author(s):  
Varunkumar Jayakumar ◽  
Jaiswal Shubhalaxmi Atmaram
Keyword(s):  
Tertiary Care ◽  
Malignant Lesion ◽  
Tobacco Consumption ◽  
Diagnostic Tools ◽  
Benign Lesions ◽  
Tertiary Care Centre ◽  
Medical College ◽  
Neoplastic Lesion ◽  
Male Preponderance ◽  
Malignant Lesions

<p class="abstract"><strong>Background:</strong> The aim of the study was to (a) determine the incidence and distribution of cases according to age, sex, etiology etc; (b) to know common etiology for the different diseases; (c) to understand pathophysiology of the disease; (d) to know various presentations of the disease; (e) to determine various diagnostic tools; and (f) to know modalities of treatment available.</p><p class="abstract"><strong>Methods:</strong> Prospective observational study, method of sampling: non-random, purposive. department of ENT, Government medical college and tertiary care centre. Fifty-one patients with benign and malignant lesion of larynx were analysed. Only cases with persistent hoarseness for more than three weeks were selected. Benign lesions included neoplastic and non-neoplastic lesions. All cases underwent a thorough ENT examination. Once suspected the cases were examined under direct laryngoscope, fibreoptic laryngoscope and if needed microlaryngeal examination was also done.   </p><p class="abstract"><strong>Results:</strong> The study showed 86.6% benign lesions and 41.1% malignant lesions of larynx with male preponderance. It was observed that vocal polyp was the commonest benign non-neoplastic lesion and papilloma was the commonest neoplastic lesion. Squamous cell carcinoma accounted predominantly in malignant lesions and was commonly found in glottis.</p><p class="abstract"><strong>Conclusions:</strong> Thus, this study reflects there is an urge to raise awareness and educate people regarding detrimental effects of vocal abuse, alcohol and tobacco consumption, preventive measures, early symptoms and availability of diagnostic tools, so that early diagnosis and appropriate treatment can be executed to reduce the morbidity and mortality.</p>

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