Clinical Presentation and Outcomes of Surgery for Upper Extremity Lipomas

2021 ◽  
Vol 23 (6) ◽  
pp. 393-400
Author(s):  
Andrzej Żyluk
Keyword(s):  
Upper Extremity ◽  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Clinical Manifestations ◽  
Benign Neoplasms ◽  
Fat Tissue ◽  
Benign Lesions ◽  
Telephone Interviews ◽  
Postoperative Scar

Background. Lipomas are benign neoplasms arising from fat tissue, with an incidence in the upper extremity of 1%-3,8%. There is scarce literature on the outcomes of the treatment of lipomas in this region. The objective of this study was to assess clinical manifestations and outcomes of surgery for upper extremity lipomas. Material and methods. The sample comprised 40 patients, including 26 women (65%) and 14 men (35%), at a mean age of 37 years, with lipomas located in the upper limbs. Treatment outcomes were assessed at a mean of 4.2 years after surgery in 27 patients from this group. Results. Most of the tumours (29 cases, 73%) were located in the forearm and arm, with 11 patients (27%) presenting with lipomas of the metacarpus and wrist. In 35 patients (87%), lesions were located superficially, within subcutaneous tissue, whereas in 5 (13%) they were located more deeply, in the metacarpus and in the forearm muscles. The follow-up assessment was conducted as telephone interviews in 27 patients. No recurrence was noted. Seven patients (26%) complained of mild tenderness of the postoperative scar. Conclusions. 1. Lipomas are moderately frequent benign lesions occurring in the upper limb. 2. Surgical treat­ment is effective and the recurrence rate is very low.

Infratentorial angioleiomyoma: a new location for a rare neoplastic entity

2009 ◽  
Vol 110 (4) ◽  
pp. 670-674 ◽  
Author(s):  
Jaime Gasco ◽  
Brodus Franklin ◽  
Leonardo Rangel-Castilla ◽  
Gerald A. Campbell ◽  
Mahmoud Eltorky ◽  
...  
Keyword(s):  
Surgical Management ◽  
English Language ◽  
Clinical Presentation ◽  
Subcutaneous Tissue ◽  
Lower Extremities ◽  
Benign Neoplasms ◽  
Middle Aged ◽  
New Location

Angioleiomyomas are benign neoplasms most often located in the subcutaneous tissue of middle-aged individuals and usually confined to the subcuticular and deep dermal layers of the lower extremities. An intracranial site for this tumor is exceedingly rare, with very few reports documenting locations in the neuraxis. To the authors' knowledge the present case represents the first reported instance of an infratentorial angioleiomyoma. The authors conducted a review of selected English-language papers published since 1960 describing well-documented cases of intracranial vascular leiomyomas, with detailed information on the clinical presentation, radiology, pathology, and particulars of surgical management in each case.

scholarly journals Mucocele of the glands of blandin nuhn: a case report

2013 ◽  
pp. 46-47 ◽  
Author(s):  
Nathalia García-León ◽  
Gilberto E Marrugo
Keyword(s):  
Case Report ◽  
Oral Cavity ◽  
Clinical Presentation ◽  
Surgical Excision ◽  
Diagnosis And Treatment ◽  
Vascular Lesions ◽  
Benign Lesions ◽  
Recurrent Lesion ◽  
Timely Diagnosis

Mucoceles arising from the Blandin Nuhn glands are uncommon benign lesions of the oral cavity, which by their clinical presentation may be confused with more serious diseases such as vascular lesions, pyogenic granulomas, polyps, or squamous papillomas; thereby, it is convenient to be aware of the characteristics of this entity to guide the accurate and timely diagnosis and treatment. Herein, we present a case of a 10-year-old patient with a recurrent lesion of this type, which required surgical excision and marsupialization of the same, with no evidence of recurrence during follow-up.

scholarly journals Histopathological spectrum of vulvar lesions on a remote Indian Island

2021 ◽  
Vol 6 (3) ◽  
pp. 153-159
Author(s):  
Chitrawati Bal Gargade ◽  
Archana Hemant Deshpande ◽  
Seetu Palo
Keyword(s):  
Clinical Presentation ◽  
Wide Spectrum ◽  
Benign Neoplasms ◽  
Benign Lesions ◽  
Duct Cyst ◽  
Neoplastic Lesion ◽  
Number Of Patients ◽  
Histopathologic Diagnosis ◽  
Neoplastic Lesions ◽  
Malignant Lesions

A wide spectrum of normal, benign, premalignant, and malignant lesions may occur on the vulva. Symptoms of vulvar disorders may be non-specific. Empiric treatment of vulvovaginal symptoms is common but usually not helpful. Though the varied clinical presentation and diverse histopathological spectrum of vulvar lesions have amazed Pathologists, only a few studies have been reported in the literature. The present study consists of a histopathological spectrum of vulvar lesions. 1.To evaluate the histopathological spectrum of vulvar lesions. 2. To compare the incidences of non-neoplastic and neoplastic lesions of the vulva. Present study includes all types of vulvar lesion specimens received in the Department of pathology over a period of four years.    All thirty-nine vulvar biopsies received in the Department of Pathology were studied for histomorphologic features. The lesions were categorized as non-neoplastic, neoplastic. The neoplastic ones were further divided into benign, malignant, and premalignant. The age of the women ranged from 15 to 69 years (mean 36.18±12.71) with the maximum number of patients between 30 to 40 years of age. Non neoplastic lesions were more common (22; 56.4%) than the (17; 43.6%) neoplastic lesions. There were 15(38.5%) benign lesions while 2 cases (5.13%) were malignant. Among the non-neoplastic lesions, Bartholin's duct cyst was the most common histopathologic diagnosis (35.9%). The fibroepithelial polyp was the most common benign neoplastic lesion constituting 15.3%.  In the present study nonneoplastic lesions were more common than neoplastic lesions. Among the neoplastic lesions, benign neoplasms were more frequent than malignant lesions.

scholarly journals Infectious Alertness in Removal Benign Neoplasms in the Maxillofacial Area

2020 ◽  
Vol 5 (5) ◽  
pp. 236-241
Author(s):  
V. N. Yadchenko ◽  
◽  
I. O. Pohodenko-Chudakova ◽  
E. S. Yadchenko ◽  
◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Soft Tissues ◽  
Subcutaneous Tissue ◽  
Clinical Manifestations ◽  
Diagnostic Methods ◽  
Benign Neoplasms ◽  
Humid Climate ◽  
Maxillofacial Region ◽  
European Continent ◽  
Surgical Interventions

Human dirofilariasis is a parasitic disease, transmissible helminthiasis caused by parasitizing nematodes of the genus Dirofilaria, most often D. repens and D. immitis which occurs with a predominant lesion of the skin (63%), conjunctiva (50%), mucous membranes, subcutaneous tissue and less often – internal organs. The most frequent incidence of dirofilariasis is observed in regions with a warm, humid climate, and at temperatures below 14℃, dirofilariae stop developing. Human cutaneous dirofilariasis on the European continent is most often diagnosed in representatives of southern and eastern Europe. There are confirmed cases of dirofilariasis on the territory of the Republic of Belarus and neighboring countries. Quite often, this disease affects the maxillofacial region. The purpose of the work was to initiate infectious alertness when planning operations for the removal of benign neoplasms in the maxillofacial region and inform medical specialists about the possibility of developing dirofilariasis of the specified localization, its clinical manifestations and objective diagnostic methods. Material and methods. The object of observation was a 34-year-old female patient R. with maxillofacial dirofilariasis. The subject of the study is the medical record of an inpatient patient R. Results and discussion. At the pre-hospital stage, patient R. underwent a general clinical examination. All indicators of the tests were within the age norm. According to the results of radiation examination methods, no data confirming the parasitic etiology of the disease was obtained. Taking into account the presence of a rounded formation about 1.0-1.2 cm in diameter which is slightly displaced relative to the underlying and surrounding soft tissues, the patient was offered surgical treatment. During the operation, a rounded self-moving helminth was extracted from the formation, about 11.0 cm long and 0.15 cm in diameter. After the helminth was identified, the patient was diagnosed with dirofilariasis. This should be taken into account in the diagnostic and therapeutic aspects when working with patients who have tumor processes in the maxillofacial region. Conclusion. The presented clinical observation shows that in the practice of a dental surgeon and a maxillofacial surgeon, it is increasingly possible to deal with the localization of helminth in the maxillofacial region which simulates a neoplasm which must be taken into account when conducting diagnostics, differential diagnosis and preoperative preparation. The results of the described case are aimed at developing infectious alertness when planning surgical interventions to remove benign neoplasms in the maxillofacial region, developing a rational diagnostic scheme and differential diagnosis for patients with suspected dirofilariasis and other parasitic lesions of the maxillofacial region

scholarly journals Subcutaneous phaeohyphomycosis: A rare case

2019 ◽  
Author(s):  
Zahruddin Ahmad ◽  
Diah Mira Indramaya ◽  
Yuri Widia ◽  
Sylvia Anggraeni ◽  
Linda Astari ◽  
...  
Keyword(s):  
Subcutaneous Tissue ◽  
Clinical Manifestations ◽  
Granulomatous Inflammation ◽  
Surgical Excision ◽  
Fungal Culture ◽  
Human Beings ◽  
Nodular Lesions ◽  
Subcutaneous Phaeohyphomycosis ◽  
Tuberculosis Therapy

Phaeohyphomycosis is a rare fungal infection caused by melanized fungi which usually involve the skin and subcutaneous tissue. It is an infrequent cause of infection in human beings. Common clinical manifestations are subcutaneous cystic swellings, which is localized, characterized by subcutaneous asymptomatic nodular lesions that develop after traumatic implantation of fungus from contaminated soil, thorns or wood splinters, especially on extremities. We report a case of subcutaneous phaeohyphomycosis presenting as multiple cystic swellings over the left lower leg with unknown predisposing factors. At first, the patient was misdiagnosed as soft tissue tumor and subcutaneous tuberculosis, then got surgical and anti-tuberculosis therapy respectively, but there was no improvement. Further investigation revealed granulomatous inflammation on histopathology examination and black-coloured colonies identifed as Exophiala dermatitidis on fungal culture. This case of phaeohyphomycosis was successfully treated by itraconazole monotherapy without surgical excision and still under follow-up.

Clinical Presentation and Treatment outcomes of Benign Renal Tumor: Angiomyolipoma

2021 ◽  
Vol 104 (8) ◽  
pp. 1354-1361
Keyword(s):  
Treatment Outcomes ◽  
Tuberous Sclerosis ◽  
Tuberous Sclerosis Complex ◽  
Clinical Presentation ◽  
Present Report ◽  
Clinical Manifestations ◽  
Flank Pain ◽  
Renal Neoplasm ◽  
Solitary Lesion

Background: Angiomyolipoma (AML) is a benign renal neoplasm composed of abnormal blood vessels, smooth muscle cells, and adipose tissue. About 40% of AMLs present with acute severe hemorrhage and is a potentially life-threatening condition. The risk of bleeding is proportional to tumor size and increasing significantly with size above 4 cm. Therefore, the patients with AMLs of 4 cm or more or spontaneous rupture of AMLs need interventional or surgical treatment. Objective: To evaluate the clinical presentation and treatment outcomes of the AMLs. Materials and Methods: The present report was a retrospective analytic study of the medical records and imaging studies in Phramongkutklao Hospital between January 2002 and December 2019. Results: Sixty-three patients, with a female:male ratio of 47:6, and a median age of 54.76 years with a range of 8 to 84 years, were included in the present analysis. Seven (11.1%) had tuberous sclerosis complex (TSC) and 56 (88.9%) had sporadic. Fifty-four had a solitary lesion, whereas nine had bilateral lesions. Asymptomatic AMLs were 50 (79.4%) and symptomatic AMLs were 13 (20.7%). There were 46 (73.0%) AMLs smaller than 4 cm and 17 (27.0%) AMLs of 4 cm or larger. AMLs smaller than 4 cm were incidentally discovered (n=40, 87%) and revealed due to symptoms such as flank pain (n=3, 6.5%) and hematuria (n=3, 6.5%). AMLs of 4 cm or larger were incidentally discovered (n=10, 58.8%) and revealed due to symptoms such as flank pain (n=7, 41.2%) and not presented with hematuria. AMLs smaller than 4 cm were mostly treated by follow up (n=39, 84.78%) or surgery (n=7, 15.22). AMLs of 4 cm or larger were treated by follow-up (n=11, 64.7%) then converted to arterial embolization (n=4, 23.5%) and converted to surgery (n=8, 47.1%). Two AMLs of 4 cm or larger died (11.8%). Conclusion: Significant differences in clinical manifestations and treatment outcomes were noted in respect to tumor characteristics, association with TSC, and treatment modality. Considering the benign nature of AML, size, and association with TSC ought to be considered when deciding upon active surveillance or prophylactic intervention. Keywords: Angiomyolipoma; Tuberous sclerosis complex; Embolization; Nephrectomy

scholarly journals Leiomiosarcoma of the Subcutaneous Tissue the Difficulties of Clinical Diagnosis: Description of a Case

2020 ◽  
pp. 1-5
Author(s):  
Alessandro Crisci ◽  
Alessandro Crisci ◽  
Michela Crisci ◽  
Raffaele D’Adamo
Keyword(s):  
Clinical Diagnosis ◽  
Clinical Presentation ◽  
Malignant Tumors ◽  
Subcutaneous Tissue ◽  
Soft Tissue Sarcomas ◽  
Review Of The Literature ◽  
Long Period ◽  
The Right ◽  
Slow Growing

Aims: Leiomyosarcomas are infrequent malignant tumors of smooth muscle, mainly derived from blood vessels or viscera. Superficial leiomyosarcomas are rare soft tissue sarcomas resulting from the dermis or subcutaneous tissue. They show a preference for proximal ends and tend to be slow-growing. They clearly show different histological and prognostic characteristics depending on whether they are cutaneous or subcutaneous. Case Report: We reported the case of subcutaneous leiomyosarcoma resulting in the medial subinguinal region of the right thigh in a 58-year-old female. Leiomyosarcoma is an entity whose clinical presentation may appear non-specific, making diagnosis difficult. We discussed the case with a brief review of the literature and the difficulties of a first approach clinical diagnosis. Conclusion: In conclusion, a long period of patient follow-up is recommended to capture a subsequent malignant progression of the disease.

scholarly journals Endoscopic Endonasal Transsphenoidal Approach for the Surgical Treatment of Pituitary Apoplexy and Clinical Outcomes

2021 ◽  
Vol 20 ◽  
pp. 153303382110430
Author(s):  
Zhixiang Sun, MD ◽  
Xintao Cai, MD ◽  
Yu Li, MD ◽  
Dongqi Shao, MD ◽  
Zhiquan Jiang, PhD
Keyword(s):  
Surgical Treatment ◽  
Pituitary Apoplexy ◽  
Clinical Manifestations ◽  
Transsphenoidal Approach ◽  
Endoscopic Endonasal ◽  
Medical College ◽  
Telephone Interviews ◽  
Vision Defects ◽  
Visual Disturbances

Purpose: This study investigated the clinical manifestations, surgical method, and treatment outcomes of patients with pituitary apoplexy and evaluated the safety and effectiveness of the endoscopic endonasal transsphenoidal approach in the treatment of pituitary adenomas. Patients and methods: In this retrospective study, were analyzed the data of patients with symptomatic pituitary apoplexy who received surgical treatment by endoscopic endonasal transsphenoidal approach from January 2017 to June 2020 at the Department of Neurosurgery of the First Affiliated Hospital of Bengbu Medical College. Patients were followed up through outpatient visits and telephone interviews. Results: Data for 24 patients including 13 males and 11 females with an average age of 46.46 years were analyzed. Headache (83.33%) and visual disturbances (75.00%) were the most common preoperative manifestations. In the 24 patients, 21 (87.50%) tumors were completely removed and 3 (12.50%) were partly removed. Intractable headache improved in all patients over a mean follow-up time of 25.16 months, and postoperative improvement in visual acuity was achieved in 17 of 18 patients (94.44%) with vision defects. Four patients (16.67%) experienced transient urinary collapse after the operation. No intracranial infection, carotid artery injury, or death occurred. Conclusion: The endoscopic endonasal transsphenoidal approach is a safe and effective method for the treatment of pituitary apoplexy.

scholarly journals Quando hipertensão arterial persistente no adolescente tem uma origem endócrina rara: relato de dois casos e revisão da literatura

2017 ◽  
Vol 27 (3) ◽  
pp. 26960
Author(s):  
Clara Gomes ◽  
Gabriela Laranjo ◽  
Elisabete Santos ◽  
Cristina Faria
Keyword(s):  
Blood Pressure ◽  
Clinical Presentation ◽  
Pediatric Population ◽  
Clinical Manifestations ◽  
Pathological Examination ◽  
Left Adrenal Gland ◽  
Ultrasound Computed Tomography ◽  
Lower Morbidity

*** When persistent hypertension  in adolescents has a rare endocrine etiology: report of two cases and literature review ***AIMS: To report two clinical cases of pheochromocytoma, a rare tumor in the pediatric population, that affects the adrenal medulla, is malignant in up to 47% of cases,  and whose clinical manifestations result from hypersecretion of catecholamines.CASE DESCRIPTION: Two cases of pheochromocytoma in adolescents are described, both with persistent hypertension and one with headache, sweating, and tachycardia. Renal and adrenal ultrasound, computed tomography angiography, and measurements of catecholamines and their metabolites revealed pheochromocytoma in the left adrenal gland. Adrenalectomy was performed after pretreatment with α-blockers. Pathological examination confirmed the diagnosis. Blood pressure returned to normal in both patients after treatment.CONCLUSIONS: Pheochromocytoma has a varied and nonspecific clinical presentation, but this condition should always be considered in the differential diagnosis of high blood pressure. Early diagnosis may imply a less aggressive treatment, lower morbidity, and a lesser impact on patients’ quality of life. The high likelihood of recurrence of pheochromocytoma, including as metastatic disease, requires follow-up visits for several years after its initial clinical presentation, even in the case of an apparent cure.

scholarly journals RETROSPECTIVE STUDY OF HISTOLOGICAL ANALYSIS AND ITS CORRELATION WITH CLINICAL PRESENTATION AND OUTCOME OF IGA NEPHROPATHY FROM A TERTIARY CENTRE OF GUWAHATI ASSAM.

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Manjuri Sharma ◽  
Manzoor Ahmad Parry ◽  
Hamad Jeelani ◽  
Pranab Jyoti Mahanta
Keyword(s):  
Retrospective Study ◽  
Iga Nephropathy ◽  
Clinical Presentation ◽  
Interstitial Fibrosis ◽  
Clinical Manifestations ◽  
Tubular Atrophy ◽  
Glomerular Diseases ◽  
Mesangial Hypercellularity ◽  
Endocapillary Hypercellularity

Background: IgA nephropathy (IgAN) is one of the most common glomerular diseases with varied presentations. We aimed to study clinical presentation and outcome of IgAN and correlate with histopathology at the time of presentation. Methods: This is a retrospective study in which we analyzed kidney biopsy data, clinical manifestations and outcome of 137 patients with a diagnosis of primary IgAN from 2012 to 2016. Kidney biopsies were reviewed as per Oxford classification assessing mesangial hypercellularity, endocapillary hypercellularity, segmental sclerosis/adhesion, tubular atrophy/interstitial fibrosis. Correlation analysis was done for biopsy findings and clinical presentation/outcome. P score less than 0.05 was taken as significant. Results: Mean age for presentation was 27.35 years with 83 males and 54 females. Asymptomatic urinary abnormality was the most common clinical presentation (28.5%). Mean serum creatinine was 2.23 ± 2.06mg/dl with mean proteinuria of 1.49 ± 1.43g/day. Mesangial hypercellularity (M) and Endocapillary hypercellularity (E) lesions were significantly associated with proteinuria at the time of biopsy (p=0.02& 0.04 respectively). Segmental glomerulosclerosis (S) and tubular atrophy (T) were significantly associated with eGFR and mean arterial pressure at the time of biopsy. Mean time of follow up was 1.6 years. M1, E0, S1, T0 were the most common lesions. M, S and T lesions in biopsy were significantly associated with decrease in GFR at the end of follow up. Conclusion: In our study, most common presentation of IgAN was AUA with rarity of macroscopic hematuria. M, S and T lesions were associated with decreased GFR on follow up. Key words: IgA Nephropathy, Nephrotic Syndrome, Oxford MEST classification

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