scholarly journals Spectrum of all microorganism isolated from surgical site infection and their antimicrobial susceptibility profile

2021 ◽  
Vol 7 (4) ◽  
pp. 246-249
Author(s):  
Sudhir Singh ◽  
Mushk Bar Fatma ◽  
Umar Farooq ◽  
Vasundhara Sharma ◽  
Shweta R Sharma ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
Nosocomial Infection ◽  
Surgical Site Infection ◽  
Antimicrobial Susceptibility ◽  
Cost Of Care ◽  
Site Infection ◽  
Healthcare Associated Infection ◽  
Biochemical Tests ◽  
Pathogenic Organism ◽  
Sensitivity Pattern

Surgical site infection are the most common nosocomial infection accounting for 14% healthcare associated infection and are estimated to double the post-operative stay and significantly increase the cost of care. Surgical site infection has been considered as the third regularly occurring infection according to national nosocomial infection surveillance system.To determine the bacterial agents causing surgical site infection and antimicrobial susceptibility pattern of isolated microorganisms.: Isolate and identify pathogens of surgical site infection. To determine antimicrobial resistance and sensitivity pattern of isolated wound microbes. To determine the frequency of pathogens of surgical site infection.: Samples were cultured on Blood agar and MacConkey agar then incubated at 37 C for 24 hours. Any growth for further confirmed by Gram stain and appropriate biochemical tests, and then Antibiotic sensitivity test was done.: In this study 106 (61.7) were of male and 66 (38.3) were of female total 172 were examined. In our study total 172 patients included in which 142 pathogenic organism were isolated. The most common pathogenic organism found to be 44 isolates (30.99%) followed by 41 isolates (28.87%) 23 isolates (16.20%), 18 isolates (12.68%), 9 isolates (6.34%), 5 isolates (3.52%), 1 isolate (0.70%) and 1 isolate (0.70%). Antimicrobial resistance always pose challenges for clinician for treating wound infection the present study guide clinician about common pathogens and countered in pus sample furthermore it help the clinician to select and treat patients with proper antibiotics and decreased mortality and morbidity.

scholarly journals Bacterial profile and antimicrobial susceptibility patterns of isolates among patients diagnosed with surgical site infection at a tertiary teaching hospital in Ethiopia: a prospective cohort study

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Gemedo Misha ◽  
Legese Chelkeba ◽  
Tsegaye Melaku
Keyword(s):  
Escherichia Coli ◽  
Cohort Study ◽  
Surgical Site Infection ◽  
Prospective Cohort Study ◽  
Antimicrobial Susceptibility ◽  
Prospective Cohort ◽  
Site Infection ◽  
Gram Negative ◽  
Tertiary Teaching ◽  
Susceptibility Patterns

Abstract Background Globally, surgical site infections are the most reported healthcare-associated infection and common surgical complication. In developing countries such as Ethiopia, there is a paucity of published reports on the microbiologic profile and resistance patterns of an isolates. Objective This study aimed at assessing the bacterial profile and antimicrobial susceptibility patterns of isolates among patients diagnosed with surgical site infection at Jimma Medical Center in Ethiopia. Methods A prospective cohort study was employed among adult patients who underwent either elective or emergency surgical procedures. All the eligible patients were followed for 30 days for the occurrence of surgical site infection (SSI). From those who developed SSI, infected wound specimens were collected and studied bacteriologically. Results Of 251 study participants, 126 (50.2%) of them were females. The mean ± SD age of the patients was 38 ± 16.30 years. The overall postoperative surgical site infection rate was 21.1% and of these 71.7% (38/53) were culture positive. On gram stain analysis, 78% of them were Gram-negative, 11.5% were Gram-positive and 10.5% were a mixture of two microbial growths. Escherichia coli accounted for (21.43%), followed by Pseudomonas aeruginosa (19.05%), Proteus species (spp.) 14.29%), Staphylococcus aureus (11.90%), Klebsiella species (11.90%), Citrobacter spp. (9.5%), streptococcal spp. (7.14%), Coagulase-negative S. aureus (CoNS) (2.38%) Conclusion Gram-negative bacteria were the most dominant isolates from surgical sites in the study area. Among the Gram-negative bacilli, Escherichia coli were the most common bacteria causing surgical site infection. As there is high antibiotic resistance observed in the current study, it is necessary for routine microbial analysis of samples and their antibiogram.

Indices of Surgical Site Infection Risk and Prediction of Other Adverse Outcomes During Hospitalization

2006 ◽  
Vol 27 (08) ◽  
pp. 825-828 ◽  
Author(s):  
Miguel Delgado-Rodríguez ◽  
Silvia Palma ◽  
Antonio Gómez-Ortega ◽  
Gabriel Martínez-Gallego ◽  
Marcelino Medina-Cuadros
Keyword(s):  
Nosocomial Infection ◽  
Surgical Site Infection ◽  
Roc Curve ◽  
Tertiary Care ◽  
Hospital Death ◽  
Consecutive Series ◽  
Care Hospital ◽  
Site Infection ◽  
Postsurgical Outcomes ◽  
Better Than

Objective.To assess which adverse postsurgical outcomes are best predicted by the Study on the Efficacy of Nosocomial Infection Control (SENIC) index and the National Nosocomial Infection Surveillance system (NNIS) index.Design.Prospective cohort study.Setting.The service of general surgery at a tertiary care hospital.Patients.A consecutive series of patients hospitalized for more than 1 day (n= 2,989).Results.The outcome best predicted by the SENIC and NNIS indices was assessed by estimating the area under the receiver operating characteristic (ROC) curve. The areas under the ROC curves for nosocomial infection and in-hospital death were higher for the NNIS index than they were for the SENIC index (P<.05). The NNIS index predicted in-hospital death better than it predicted surgical site infection (area under the ROC curve ± SE, 0.836 ± 0.022 vs 0.689 ± 0.017;P= .001).Conclusions.The NNIS index is superior to the SENIC index for all adverse postsurgical outcomes. Its ability to predict in-hospital mortality is clearly better than its ability to predict surgical site infection.

Surgical Site Infection Rates in Four Cities in Brazil: Findings of the International Nosocomial Infection Control Consortium

2016 ◽  
Vol 17 (1) ◽  
pp. 53-57 ◽  
Author(s):  
Rosana Richtmann ◽  
Erci Maria Onzi Siliprandi ◽  
Victor D. Rosenthal ◽  
Tarquino Erástides G. Sánchez ◽  
Marina Moreira ◽  
...  
Keyword(s):  
Nosocomial Infection ◽  
Infection Control ◽  
Surgical Site Infection ◽  
Site Infection ◽  
Infection Rates

scholarly journals Chlorhexidine-alcohol versus Povidone-Iodine-alcohol for surgical site antisepsis in caesarean section

2019 ◽  
Vol 8 (4) ◽  
pp. 1359
Author(s):  
Vishnu Priya Kesani ◽  
Sruthi Talasila ◽  
Sheela S. R.
Keyword(s):  
Caesarean Section ◽  
Surgical Site Infection ◽  
Povidone Iodine ◽  
Care Center ◽  
Tertiary Care ◽  
Site Infection ◽  
Healthcare Associated Infection ◽  
Skin Antisepsis ◽  
Control And Prevention ◽  
Healthcare Associated

Background: Caesarean section is one of the most common procedures performed. Recent studies found that surgical-site infection (SSI) was the most common healthcare-associated infection. Authors hypothesized that optimization of preoperative skin antisepsis may decrease postoperative infections. The objective was to establish the efficacy of chlorhexidine-based antiseptic protocol versus povidone-iodine protocol in reducing SSI for patients undergoing caesarean deliveries.Methods: This is a randomized prospective study conducted from April 2017 to September 2017 at a tertiary care center in India. Women who underwent caesarean sections were allocated into either group. Enrolled patients were randomly assigned to have the surgical site painted with chlorhexidine-alcohol preparation or painted with a solution of 10% povidone-iodine and then with surgical spirit. The outcomes were any SSI occurring within a week or during the 30 day follow up period of the surgery including any of: superficial or deep surgical site infection, or endometritis, according to Centers for Disease Control and Prevention definitions.Results: A total of 560 subjects (273 in the chlorhexidine group and 287 in the iodine group) qualified for the study. The number of surgical-site infection was significantly lower in the chlorhexidine group than in the iodine group (6.95% vs. 14.28%; P=0.005). Chlorhexidine–alcohol was significantly more protective than iodine-alcohol against both superficial incisional infections (5.49% vs. 10.10%, P=0.03) and deep incisional infections (1.46% vs. 4.18%, P=0.04).Conclusions: This study highlighted that Chlorhexidine-alcohol provided superior skin antisepsis in comparison to povidone iodine-alcohol.

Prevalence of surgical site infection and antibiotic susceptibility pattern among post-operative patients at a tertiary hospital in Lafia Nasarawa state, Nigeria

2021 ◽  
Vol 7 (4) ◽  
pp. 117-120
Author(s):  
Ikrama Hassan ◽  
◽  
Michael Anazodo ◽  
Agbo Christian Agbo ◽  
Oga Esa Ochapa ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Susceptibility ◽  
Surgical Patients ◽  
P Value ◽  
Site Infection ◽  
Susceptibility Pattern ◽  
Klebsiella Species ◽  
Mannitol Salt Agar ◽  
Antibiotic Susceptibility Pattern ◽  
Sensitivity Pattern

Background: Surgical site infection is a common challenge to both the surgical patients and the surgical specialists and may lead to morbidity and mortality. The aetiologic agents vary from one place to the other, ditto the antibiotic sensitivity pattern. This study determined the prevalence of surgical site infection, the aetiologic agents and the antibiotic susceptibility pattern in a tertiary health facility in Lafia. Methods: The study was carried out over 5 (2015 – 2019) year period on post operative patients at the Dalhatu Araf Specialist Hospital (DASH) in the surgical and obstetrics and gynaecological wards. Swab taken from infected wounds were cultured using 2 plates of blood agar, MacConkey agar and Mannitol salt agar. The antibiotic susceptibility testing was done using Kirby Bauer technique. The data was analysed using SPSS version 23. Results obtained were presented in tables. Significant p value is < 0.05. Results: The mean age of the respondents is 28.6 ± 11.2 years. Of the 408 surgical patients seen within the 5 year period, 15 (3.7%) had surgical sites infection given a prevalence of 3.7%. A total of 6.6% of the patients who had undergone surgeries were immune-compromised. Escherichia coli and Klebsiella species were the two cultured organisms accounting for 75% and 25% respectively. Antibiotic susceptibility revealed that all (100%) were sensitive to the quinolone (ciprofloxacin). Conclusion: Surgical site infection is most common in the third decade of life with a mean age of 28.6 ± 11.2 years. There is a low prevalence of surgical site infection from this study. Eschericia coli and Klebsiella species were the two common organism isolated with both having a good sensitivity to ciprofloxacin

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