scholarly journals Surgical Site Infection: The Rate and Antimicrobial Sensitivity Pattern in Electively Operated Surgical and Gynecological Patients at Kilimanjaro Christian Medical Centre, Northern Tanzania

2017 ◽  
Vol 3 (1) ◽  
pp. 001-005
Author(s):  
AM Herman ◽  
G Massenga ◽  
KS Chilonga ◽  
RN Philemon ◽  
D Katundu
Author(s):  
Tasilo Kamenya ◽  
Damian Jeremia Dami ◽  
James Samwel Ngocho ◽  
Rune Nathanael Philemon ◽  
Michael Johnson Mahande ◽  
...  

Author(s):  
Sudhir Singh ◽  
Mushk Bar Fatma ◽  
Umar Farooq ◽  
Vasundhara Sharma ◽  
Shweta R Sharma ◽  
...  

Surgical site infection are the most common nosocomial infection accounting for 14% healthcare associated infection and are estimated to double the post-operative stay and significantly increase the cost of care. Surgical site infection has been considered as the third regularly occurring infection according to national nosocomial infection surveillance system.To determine the bacterial agents causing surgical site infection and antimicrobial susceptibility pattern of isolated microorganisms.: Isolate and identify pathogens of surgical site infection. To determine antimicrobial resistance and sensitivity pattern of isolated wound microbes. To determine the frequency of pathogens of surgical site infection.: Samples were cultured on Blood agar and MacConkey agar then incubated at 37 C for 24 hours. Any growth for further confirmed by Gram stain and appropriate biochemical tests, and then Antibiotic sensitivity test was done.: In this study 106 (61.7) were of male and 66 (38.3) were of female total 172 were examined. In our study total 172 patients included in which 142 pathogenic organism were isolated. The most common pathogenic organism found to be 44 isolates (30.99%) followed by 41 isolates (28.87%) 23 isolates (16.20%), 18 isolates (12.68%), 9 isolates (6.34%), 5 isolates (3.52%), 1 isolate (0.70%) and 1 isolate (0.70%). Antimicrobial resistance always pose challenges for clinician for treating wound infection the present study guide clinician about common pathogens and countered in pus sample furthermore it help the clinician to select and treat patients with proper antibiotics and decreased mortality and morbidity.


2021 ◽  
Vol 7 (4) ◽  
pp. 117-120
Author(s):  
Ikrama Hassan ◽  
◽  
Michael Anazodo ◽  
Agbo Christian Agbo ◽  
Oga Esa Ochapa ◽  
...  

Background: Surgical site infection is a common challenge to both the surgical patients and the surgical specialists and may lead to morbidity and mortality. The aetiologic agents vary from one place to the other, ditto the antibiotic sensitivity pattern. This study determined the prevalence of surgical site infection, the aetiologic agents and the antibiotic susceptibility pattern in a tertiary health facility in Lafia. Methods: The study was carried out over 5 (2015 – 2019) year period on post operative patients at the Dalhatu Araf Specialist Hospital (DASH) in the surgical and obstetrics and gynaecological wards. Swab taken from infected wounds were cultured using 2 plates of blood agar, MacConkey agar and Mannitol salt agar. The antibiotic susceptibility testing was done using Kirby Bauer technique. The data was analysed using SPSS version 23. Results obtained were presented in tables. Significant p value is < 0.05. Results: The mean age of the respondents is 28.6 ± 11.2 years. Of the 408 surgical patients seen within the 5 year period, 15 (3.7%) had surgical sites infection given a prevalence of 3.7%. A total of 6.6% of the patients who had undergone surgeries were immune-compromised. Escherichia coli and Klebsiella species were the two cultured organisms accounting for 75% and 25% respectively. Antibiotic susceptibility revealed that all (100%) were sensitive to the quinolone (ciprofloxacin). Conclusion: Surgical site infection is most common in the third decade of life with a mean age of 28.6 ± 11.2 years. There is a low prevalence of surgical site infection from this study. Eschericia coli and Klebsiella species were the two common organism isolated with both having a good sensitivity to ciprofloxacin


2013 ◽  
Vol 11 (2) ◽  
pp. 18-20
Author(s):  
Sushila Devi Bhandari

Introduction: Surgical site infection is a common occurrence in surgical ward. Knowledge about the commonest pathogen and its sensitivity in a particular setting is crucial in selection of appropriate antibiotics. No study has been performed earlier to identify the pattern of infection and antibiotic sensitivity in surgical department. So, this study aimed to analyze the commonest isolates from surgical site infection and their sensitivity pattern. Methods: A total of 56 cases of surgical site infection who were admitted in surgical ward at Shree Birendra Hospital, were included in this study. Wound swab from the infected surgical site was taken and send for culture and sensitivity. The obtained results were analysed using descriptive tools. Results: Among 56 surgical site infections only in 30 cases a pathogen was isolated. The commonest organism isolated was E.Coli 15(50%) followed by Staph. Aureus. The most sensitive antibiotics was Amikacine for E. Coli, and cefixime for S. Aureus. Conclusions: Ciprofloxacin seems to be the most appropriate first line oral antibiotics as it is sensitive both to E. Coli and S Aureus.Medical Journal of Shree Birendra Hospital; July-December 2012/vol.11/Issue2/18-20 DOI: http://dx.doi.org/10.3126/mjsbh.v11i2.7903  


Author(s):  
Neha Thakur ◽  
Avinashi Kujur

Background: It is one of the most common surgery practiced in present era in obstetric population it has led to rise in postoperative morbidity in the form of surgical site infection (SSI). It not only burdens the health system but it also puts a serious negative impact on patient’s life. The present study is aimed to determine the incidence, risk factors and the microbiological and antibiotic sensitivity pattern for SSI following caesarean section in our institute.Methods: The study is prospective, descriptive study carried out in department of obstetrics and gynecology of Pt. Jawaharlal Nehru medical college, Raipur between May 2019 and April 2020.Results: Out of the 1215 participants who underwent caesarean section, 251 patients had SSI, with incidence of 20.6% among them superficial SSI (n=154) was 61.3% while deep SSI (n=75) 29.8% and 8.7% (n=22) organ/space SSI. Gram positive organism was highest isolated from superficial SSI 66.2% while from deep SSI and organ/space SSI gram positive organism isolated was 45.2% and 54.2% respectively, gram negative organisms were maximum isolated from organ/space SSI 40.9%followed by deep and superficial SSI 36% and 34.4% respectively. Most isolates were highly resistant to cephalosporins, gentamycin and amoxicillin; moderately resistant to fluoroquinolones and highly sensitive to vancomycin, carbapenem and linezolid.Conclusions: Our tertiary centre had post caesarean SSI rate of 20.6% which was high. By analyzing the microbiological and sensitivity pattern we can use evidenced-based sensitive antibiotics to be commenced initially when wound infection is identified in our wards while awaiting the result of wound swab microscopy, culture and sensitivity (48-72 hours), to individualize our antibiotic prophylaxis and postoperative antibiotic protocol policy to reduce the further complications.


Antibiotics ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 622
Author(s):  
Abdikarim Hussein Mohamed ◽  
Hussein Ali Mohamud ◽  
Ebubekir Arslan

Background: Surgical site infection is the most common kind of nosocomial infection in developed and developing countries. Objectives: Our aim was to identify the prevalence of factors predisposing to multidrug resistance and the antimicrobial susceptibility profile of pathogens. Method: This retrospective study enrolled 10,878 patients who underwent operations in 2018–2020. Pathogens were identified using eosin methylene blue agar. Mueller–Hinton agar was used to assess antimicrobial sensitivity and resistance. In total, 382 patients with confirmed surgical site infection (SSI), whose culture showed growth, were included in the study. Results: The prevalence of SSI in the current study was 3.5%. Escherichia coli was the predominant pathogen (35.8%), followed by Staphylococcus aureus (21.8%). Antibiotic use, chronic renal failure, diabetes, and emergency operations were found to increase the likelihood of multidrug resistance (OR = 6.23, CI = 1.443–26.881, p = 0.014; OR = 5.67, CI = 1.837–19.64, p = 0.02; OR = 2.54, CI = 1.46–7.35, p = 0.03; OR = 1.885, CI = 1.067–3.332, p = 0.002, respectively). The pathogens showed different levels of antimicrobial resistance against ceftriaxone (72.7%), ciprofloxacin (46.6%), and gentamicin (34%). Antimicrobial resistance of about 1–3.4% was exhibited by linezolid, tigecycline, and teicoplanin. Conclusion: The study presented significantly increased multidrug-resistant (MDR) Enterobacteriaceae pathogens isolated from surgical sites. They involve significant morbidity and mortality rates and increased health-related costs.


2015 ◽  
Vol 2 (2) ◽  
pp. 118 ◽  
Author(s):  
Hemant Borse ◽  
Rahul Shelke

<strong>Aim</strong>: The objectives of this study was to study the various micro-organisms causing surgical site infection, to study their antibiotic sensitivity and resistance pattern. <strong>Setting</strong>: Department of Surgery of a tertiary health care centre with an attached medical college. <strong>Material and methods</strong>: A total of 89 patients with post operative surgical site infection occurring within 30 days of surgery or 1 year of implant were included as subject material after they satisfy inclusion and exclusion criteria. <strong>Results</strong>: <em>E.coli</em> is the commonest organism isolated in SSI wounds. Overall Imipenem and Amikacin are the most sensitive antibiotics. Over all gentamycin, cefotaxime and clindamycin are the most resistant antibiotics noted. <strong>Conclusion</strong>: The most common organisms associated with SSI are <em>E. coli</em> and Pseudomonas. Most of the organisms were sensitive to imipenem, amikacin. Sensitivity pattern of the of the organism is changing with time. The common organisms are now no longer sensitive to routinely used cheaper antibiotics. Newer antibiotics, which are more costly, are required to treat the infection which is a burden to the patient.


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