Turcot Syndrome: A Synchronous Clinical Presentation of Medulloblastoma and Lower Rectal Tumor

We report the case of a 16-year-old patient who was operated for medulloblastoma with simple operative followup after radio and chemotherapy. Two years later, she was admitted, in a state of cachexia, for abdominal pain and rectorrhagia. The explorations found an infected lower rectal tumor. The patient underwent an urgent surgery. Immediate consequences were marked by the installation of a severe septic shock causing the patient’s death.

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NSRG-07. TURCOT SYNDROME: A SYNCHRONOUS CLINICAL PRESENTATION OF MEDULLOBLASTOMA AND LOWER RECTAL TUMOR

Neuro-Oncology ◽

10.1093/neuonc/noy059.529 ◽

2018 ◽

Vol 20 (suppl_2) ◽

pp. i147-i147

Author(s):

Mehdi Borni ◽

Fatma Kolsi ◽

Anis Abdelhedi ◽

Firas Jarraya ◽

Mohammed Zaher Boudawara

Keyword(s):

Clinical Presentation ◽

Rectal Tumor ◽

Turcot Syndrome

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Enucleation of a giant symptomatic gastric lipoma, a safe surgical approach

Journal of Surgical Case Reports ◽

10.1093/jscr/rjab087 ◽

2021 ◽

Vol 2021 (3) ◽

Author(s):

Rafaela Parreira ◽

Tiago Rama ◽

Teresa Eloi ◽

Vítor Carneiro ◽

Maria Inês Leite

Keyword(s):

Computed Tomography ◽

Abdominal Pain ◽

Clinical Presentation ◽

Pyloric Obstruction ◽

Asymptomatic Patients ◽

Recurrent Vomiting ◽

Low Incidence ◽

Diagnostic Modalities ◽

Benign Tumours ◽

Gastric Lipoma

Abstract Gastric lipomas are rare, representing 2–3% of all benign tumours of the stomach. Most of these stomach neoplasms are small and detected incidentally during endoscopic or radiology evaluations. Computed tomography is highly specific imaging for lipoma diagnosis. Endoscopy and endoscopic ultrasound are other important diagnostic modalities to confirm the diagnosis. Identifying typical features can avoid biopsy or surgery in asymptomatic patients. In patients with larger lesions, usually more than 2 cm, clinical presentation may encompass haemorrhage, abdominal pain, pyloric obstruction and dyspepsia. As a result of its extreme low incidence, treatment is not standardized, though it is widely accepted that a symptomatic tumour mandates resection. Here, we present the case of a 60-year-old female presenting with abdominal pain and recurrent vomiting due to a giant gastric lipoma (80 × 35 × 35 mm). The patient underwent laparotomy and an enucleation was performed.

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Post-COVID-19 Kawasaki-Like Syndrome

Ear Nose & Throat Journal ◽

10.1177/01455613211006011 ◽

2021 ◽

pp. 014556132110060

Author(s):

Jérôme R. Lechien ◽

Rémi Hervochon ◽

Stéphane Hans

Keyword(s):

Abdominal Pain ◽

Multiple Organ Failure ◽

Organ Failure ◽

Hepatitis A ◽

Clinical Presentation ◽

Multiple Organ ◽

Mild Form ◽

Severe Dysphagia ◽

History Of ◽

Inflammatory Syndrome

A 42-year-old man was referred for a week history of severe dysphagia, odynophagia, fever (39 °C), fatigue, abdominal pain, pharyngeal swelling, and multiple neck lymphadenopathies. The medical history reported a mild form of COVID-19 one month ago. The biology reported an unspecified inflammatory syndrome. The patient developed peritonitis, myocarditis, and hepatitis. A myocardium biopsy was performed. A diagnosis of Kawasaki-like disease (KLD) was performed. The occurrence of KLD in adults is rare but has to be known by otolaryngologists regarding the otolaryngological clinical presentation that may precede the multiple organ failure.

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Analysis of Gastrointestinal Symptoms in 281 Cases of Hospitalized Covid 19 Patients, Single-Center Study

The Journal of Tepecik Education and Research Hospital ◽

10.5222/terh.2021.73603 ◽

2021 ◽

Author(s):

Gözde Derviş Hakim ◽

Şükran Köse ◽

Pınar Şamlıoğlu ◽

Cengiz Ceylan ◽

Mehmet Can Uğur ◽

...

Keyword(s):

Abdominal Pain ◽

Respiratory Symptoms ◽

Clinical Presentation ◽

Gastrointestinal Symptoms ◽

Clinical Analysis ◽

Clinical Findings ◽

Gastrointestinal System ◽

Detailed Review ◽

Single Center Study ◽

Gi Symptoms

Objective: Although Covid-19 which has been identified as the disease caused by SARS COV-2 virus mainly affects the respiratory tract, it was observed that many systems were affected. The gastrointestinal system is one of the main systems involved. The aim of this manuscript was to perform epidemiological, virological, and clinical analysis of 59 Covid 19-positive patients with gastrointestinal symptoms. Method: Covid-19 diagnosed patients have been started to be admitted since March, 20, 2020. Epidemiological, demographical, clinical findings, laboratory analyses as well as hospitalization periods and disease progression of the patients presenting gastrointestinal system (GIS) symptoms admitted between March, 31, 2020 and August, 1, 2020. Results: Totally 710 Covid 19-positive patients hospitalized were screened. Among these patients, those with incomplete medical history and deficient data were excluded. The analysis of 281 patients admitted due to Covid-19 diagnosis with complete data since admission revealed that 59 patients presented GIS symptoms at admission. The aforesaid patients were compared with 222 patients admitted due to Covid-19 without GIS symptoms within the same period. GIS symptoms were detected on 59 (59/281) (20.99%) patients admitted due to Covid-19. Detailed review of these patients revealed that 18 (18/59) (30.50%) patients had nausea-vomiting, 10 (10/59) (16.95%) patients had abdominal pain, and 31 (31/59) (52.55%) patients had GIS bleeding. It was observed that vomiting was added into the clinical presentation in 7 of 18 patients. Although there is not any diarrhea symptom alone, total number of cases with diarrhea+abdominal pain, diarrhea+nausea-vomiting, diarrhea+nausea-vomiting+abdominal pain was 17 (17/59) (28.81%) of 59 patients. Conclusion: According to the results of this study, we have found 20.99% gi symptoms in the hospitalizated patients due to Covid 19. Although GIS symptoms are not associated with disease severity, they are important for the identification and spread of the disease, along with respiratory symptoms.

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Effects of norepinephrine on hemodynamics, vascular elasticity, cardiac pump function, and inflammatory factors in patients with septic shock

European Journal of Inflammation ◽

10.1177/2058739219838396 ◽

2019 ◽

Vol 17 ◽

pp. 205873921983839

Author(s):

Fengzhi Wang ◽

Mancui Zhang ◽

Xiujuan Wang ◽

Xiaopeng Zhong ◽

Po Ding

Keyword(s):

Septic Shock ◽

Blood Vessel ◽

Inflammatory Factors ◽

Control Group ◽

Pump Function ◽

Heart Pump ◽

Cardiac Pump Function ◽

Vascular Elasticity ◽

Experimental Group ◽

Severe Septic Shock

The effects of norepinephrine on hemodynamics, vascular elasticity, cardiac pump function, and inflammatory factors in patients with septic shock remained unknown. In this study, we included 124 cases of severe septic shock patients in our hospital. The patients were randomly divided into control group (treated with dopamine) and experimental group (treated with dopamine plus norepinephrine), while the hemodynamic index (heart rate (HR)), blood vessel elasticity index, heart pump function, and inflammatory factor index were recorded. After 12 h of treatment, both groups showed decreased HR, increased levels of cardiac index (CI), mean arterial pressure (MAP), central venous pressure (CVP), peripheral vascular resistance index (PVRI), and vascular elasticity ( P < 0.05). To date, lower HR, higher levels of CI, MAP, CVP, and PVRI were observed in the experimental group ( P < 0.05). Furthermore, the vascular elastic coefficient, stiffness index, arterial compliance, and the precursors of plasma amino-terminal brain natriuretic peptide were also significantly higher in the experimental group than those in the control group ( P < 0.05). However, inflammatory cell tumor necrosis factor alpha factor test group (TNF alpha), interleukin-1 (IL-1), and interleukin-6 (IL-6) concentrations were significantly lower than the control group ( P < 0.05), compared to experimental group ( P < 0.05). This research indicates that phenylephrine could significantly improve hemodynamics in patients with severe septic shock, by maintaining blood vessel elasticity, improving heart pump function, and reducing the inflammatory factors’ activities, and this method could be used as a line of vascular tension of the medications used in patients with septic shock.

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Bali Belly: Salmonella senftenberg Found in an Infected Ovarian Endometrioma

Case Reports in Obstetrics and Gynecology ◽

10.1155/2020/3581091 ◽

2020 ◽

Vol 2020 ◽

pp. 1-3

Author(s):

P. D. M. Pathiraja ◽

Junaid Rafi ◽

Emily Woolnough ◽

Anna Clare

Keyword(s):

Septic Shock ◽

Abdominal Pain ◽

Pelvic Inflammatory Disease ◽

Antibiotic Treatment ◽

Bacterial Translocation ◽

Inflammatory Disease ◽

Peritoneal Fluid ◽

Ovarian Endometrioma ◽

Surgical Evacuation ◽

Salmonella Senftenberg

Salmonella is an extremely rare cause of an infected endometrioma. We present a case of a 30-year-old immunocompetent woman presenting with fevers and abdominal pain, on a background of prior endometriosis. Initial antibiotic treatment for pelvic inflammatory disease failed, and the patient progressed to septic shock requiring surgical evacuation of an infected ovarian endometrioma. Microbiological samples from stool, ovary, and peritoneal fluid revealed infection with Salmonella senftenberg. The likely diagnosis was Salmonella enterocolitis with bacterial translocation to an ovarian endometrioma.

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Transverse vaginal septum presenting as secondary amenorrhoea: a rare clinical presentation

BMJ Case Reports ◽

10.1136/bcr-2020-235374 ◽

2020 ◽

Vol 13 (8) ◽

pp. e235374 ◽

Cited By ~ 1

Author(s):

Garima Yadav ◽

Neha Agrawal ◽

Sureka Binit ◽

Pratibha Singh

Keyword(s):

Differential Diagnosis ◽

Abdominal Pain ◽

Menstrual Cycle ◽

Clinical Presentation ◽

Primary Amenorrhea ◽

Early Age ◽

Cell Debris ◽

Vaginal Septum ◽

Secondary Amenorrhea ◽

Transverse Vaginal Septum

Transverse vaginal septum is one of the variants of Mullerian duct anomaly, caused as a result of defective fusion or recanalisation of vaginal and Mullerian organs. At an early age, it commonly presents as primary amenorrhea along with cyclical abdominal pain while later on usually it presents as dyspareunia and infertility. Our 22-year-old patient presented with secondary amenorrhea. It is very unusual for a transverse vaginal septum to cause secondary amenorrhea. MRI and clinical examination raised the suspicion of transverse vaginal septum causing secondary amenorrhea. She attained regular menstrual cycle after septum excision. The proposed theory behind it is obliteration of microperforated transverse vaginal septum because of menstrual blood and cell debris. Thus, a rare possibility of transverse vaginal septum should also be considered as a differential diagnosis of secondary amenorrhea.

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Double Perforated Kissing Ulcers of Duodenum: A Brief Report

International Surgery ◽

10.9738/intsurg-d-15-00280.1 ◽

2019 ◽

Vol 103 (1-2) ◽

pp. 36-39

Author(s):

Tania Triantafyllou ◽

Kokoroskos Nikolaos ◽

Papailiou Joanna ◽

Linardoutsos Dimitrios ◽

Zografos Georgios ◽

...

Keyword(s):

Peptic Ulcer ◽

Abdominal Pain ◽

Case Reports ◽

Duodenal Ulcers ◽

Ulcer Disease ◽

Surgical Department ◽

Helicobactor Pylori ◽

Urgent Surgery ◽

First Case ◽

Chest X Ray

Helicobactor pylori infection has been associated with peptic ulcer disease and is currently treated with proton pump inhibitors (PPIs), which have reduced the complications of the disease. Perforation of either a gastric or duodenal ulcer is rarely treated with surgery. We report the case of double-perforated synchronous duodenal ulcers, which is an extremely infrequent condition. To our knowledge, no English case reports have yet been published. Therefore, awareness of the physician in the field of diagnosis and treatment of this peptic ulcer is required. We report the case of a 46-year-old male patient who presented with acute abdominal pain at the emergency surgical department of our hospital. According to patient history, smoking, alcohol consumption, and frequent postprandial abdominal pain were noted. A physical examination revealed a rigid abdomen and tachycardia, and the temperature was 37.8°C. Laboratory testing showed increased levels of leukocytes, and free subdiaphragmatic air was found in the chest X-ray. Due to rapid deterioration of his clinical condition, the patient underwent urgent surgery. An explorative laparotomy showed 2 perforated kissing ulcers at the first segment of the duodenum, in the anterior and posterior walls. A peripheral gastrectomy was performed. Postoperative follow-up did not result in any complications. In regard to this case we present, simultaneous perforation of two synchronous duodenal ulcers is an uncommon but possible incident of which the clinician should be aware. To our knowledge, this is the first case published in the literature.

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