scholarly journals APPLICATION OF NON-INVASIVE OPTICAL TRAINABLE DIAGNOSTIC SYSTEM AND MATHEMATICAL METHODS OF PROCESSING MULTIDIMENSIONAL DATA TO ASSESS THE OXYGEN STATUS OF HUMAN TISSUES (SHORT DESCRIPTION)

2020 ◽  
Vol 30 (4) ◽  
pp. 113-118
Author(s):  
A. Yu. Zaitceva ◽  
◽  
Yu. Ya. Kislyakov ◽  
М. S. Mazing ◽  
V. V. Davydov ◽  
...  
Keyword(s):  
Experimental Studies ◽  
Diagnostic System ◽  
Diagnostic Value ◽  
Visible Spectral Range ◽  
Multidimensional Data ◽  
Human Tissues ◽  
Mathematical Methods ◽  
Non Invasive ◽  
Invasive Method ◽  
Mathematical Processing

A non-invasive method for analyzing oxygen supply for human tissues using methods of mathematical processing of multidimensional data, which has an important diagnostic value, is proposed. As a result of experimental studies with the participation of 10 subjects using a non-invasive optical trainable diagnostic system, attempts were made to collect information in conventional units by means of multichannel optical analyzer of the visible spectral range. The obtained results of mathematical processing of experimental data show that the proposed technique is effective and can be used in practical medical and biological developments.

scholarly journals MULTISENSOR OPTICAL SYSTEM FOR NON-INVASIVE MONITORING OF THE HUMAN OXYGEN BODY DURING FUNC-TIONAL STRESS

2020 ◽  
Vol 30 (4) ◽  
pp. 106-112
Author(s):  
A. Yu. Zaitceva ◽  
◽  
М. S. Mazing ◽  
Yu. Ya. Kislyakov ◽  
◽  
...  
Keyword(s):  
Optical System ◽  
Optical Spectrum ◽  
Oxygen Supply ◽  
Experimental Studies ◽  
Multidimensional Data ◽  
Invasive Monitoring ◽  
Optical Spectrum Analyzer ◽  
Mathematical Methods ◽  
Practical Medicine ◽  
Non Invasive

This work was performed using optical spectroscopy methods. The proposed method is based on the differences in the absorption spectra of oxyhemoglobin and reduced hemoglobin, as well as on the analysis of the response of the system using mathematical methods for processing multidimensional data. In the course of the work, a prototype of the diagnostic optical system for non-invasive monitoring of the oxygen supply of human tissues was created, which is based on a multi-channel optical spectrum analyzer. As a result of experimental studies, it was shown that each subject has his own individual, reproducible "image". The results of the study confirm the effectiveness of the proposed method for assessing the functional state of a person and the prospects for its use in practical medicine.

scholarly journals Temperature measurement methods in an experimental setup during bone drilling: A brief review on the comparison of thermocouple and infrared thermography

2021 ◽  
Vol 2129 (1) ◽  
pp. 012096
Author(s):  
Md Ashequl Islam ◽  
Nur Saifullah Kamarrudin ◽  
Ruslizam Daud ◽  
Ishak Ibrahim ◽  
Anas Rahman ◽  
...  
Keyword(s):  
Experimental Studies ◽  
Thermal Response ◽  
Drilling Process ◽  
Temperature Elevation ◽  
Bone Drilling ◽  
Ir Camera ◽  
Non Invasive ◽  
Dental Implantation ◽  
Invasive Method ◽  
Significant Opportunity

Abstract Predicting thermal response in orthopedic surgery or dental implantation remains a significant challenge. This study aims to find an effective approach for measuring temperature elevation during a bone drilling experiment by analyzing the existing methods. Traditionally thermocouple has frequently been used to predict the bone temperature in the drilling process. However, several experimental studies demonstrate that the invasive method using thermocouple is impractical in medical conditions and preferred the thermal infrared (IR) camera as a non-invasive method. This work proposes a simplified experimental model that uses the thermocouple to determine temperature rise coupled with the thermal image source approach. Furthermore, our new method provides a significant opportunity to calibrate the thermal IR camera by finding out the undetected heat elevation in a workpiece depth.

scholarly journals New Metabolic and Genetic Biomarkers for Diagnosis of Ulcerative Colitis

2021 ◽  
Author(s):  
Elena Emilia Tudoroniu ◽  
Mihaela Andreea Costache ◽  
Maria-Andreea Stancu ◽  
Anca Lucia Pop
Keyword(s):  
Ulcerative Colitis ◽  
Case Series ◽  
Diagnostic Value ◽  
Eligibility Criteria ◽  
Non Invasive ◽  
Randomized Controlled ◽  
Genetic Biomarkers ◽  
Bowel Diseases ◽  
Invasive Method ◽  
Inflammatory Bowel

Ulcerative colitis (UC) is one of the two disorders known as inflammatory bowel diseases (IBD) along with Crohn’s disease (CD), with complex pathogenesis, requiring costly invasive investigations. Objective: to examine the most recent biomarkers proposed for UC diagnosis; to establish the strategy used to make the differential diagnosis between UC and CD relying on these biomarkers, also adding the benefit of finding new non-invasive tools in managing this condition. The search was performed in a single database (Web of Science) using the specific keywords „ulcerative colitis”, „biomarkers” and „diagnosis” for the last five years. Study eligibility criteria: clinical trials on adults and pediatric patients with ulcerative colitis compared with Crohn’s disease. Results: We selected 57 studies, randomized controlled trials (RCTs) and clinical case series (CCS), summarizing the latest most specific biomarkers in diagnosis of UC. Limitations: we considered RCTs and CCS from one database, limited to the search topics. Our findings indicate a important number of potential biomarkers with diagnostic value, which bring the advantage of a non-invasive method to approach this challenging disorder.

scholarly journals Sensory Elements and Devices Operational Diagnostic Blood Glucose

2016 ◽  
Vol 17 (1) ◽  
pp. 108-113
Author(s):  
I.T. Kogut ◽  
M.V. Kotyk
Keyword(s):  
Blood Glucose ◽  
Continuous Monitoring ◽  
Diagnostic System ◽  
Basic Principles ◽  
Measuring Device ◽  
Non Invasive ◽  
Invasive Method ◽  
Personal Use ◽  
Treatment Of Diabetes ◽  
Measurement Devices

The problem of monitoring diabetes is caused as a significant prevalence of the disease, and development on this basis of complex related complications, early disability and mortality. [1] So important is operational and continuous monitoring of blood glucose (MBG), which will increase rates treatment of diabetes. Currently developed compact diagnostic system CMG for both the clinic and personal use. These systems are the most invasive, requiring immediate blood sampling. At the same time, become of diagnostic devices which are based on non-invasive method that the accuracy inferior invasive, but is more promising, because they have more functionality in terms of ease of measurement, storage and processing results. These systems include a measuring device and sensor elements. This paper will review methods and analysis of the basic principles of measurement devices MBG to develop circuit solutions for the creation of sensor and microsystem elements for noninvasive monitoring MBG.

scholarly journals C-Peptides for diagnostics and therapy: a veterinary medicine point of view

2017 ◽  
Vol 37 (1) ◽  
pp. 36-40 ◽  
Author(s):  
Derek A. Rosenfield ◽  
Marcilio Nichi ◽  
Cristiane Schilbach Pizzutto
Keyword(s):  
Veterinary Medicine ◽  
Empirical Studies ◽  
Experimental Studies ◽  
Point Of View ◽  
Diabetic Patients ◽  
C Peptide ◽  
Non Invasive ◽  
Therapeutic Benefits ◽  
Invasive Method ◽  
Positive Results

ABSTRACT: Empirical studies proved that C-peptides are performing numerous intrinsic biological roles, and serve as a marker for pancreatic performance analysis. Since the last decade, C-peptide assays for differential diagnosis in veterinary diabetic patients are becoming more available, but still only for a very limited number of species. Studies on C-peptide as a diagnostic tool, therapy for associated complications, or as replacement therapies for C-peptide deficiency still showed not to be a common practice in veterinary medicine. This review was conducted to determine the potential importance of C-peptide in Veterinary Medicine, relevant in the diagnosis of diabetes and for other metabolic processes, as well as its proposed therapeutic benefits. Numerous articles were identified that reported positive results in their experimental studies, whether C-peptide as a biomarker for pancreatic performance in dogs, cats, and horses, as a non-invasive method to monitor nutritional status in primates, or to investigate its potential therapeutic benefits for diabetes-related illnesses.

Malfunctional Reorganization in the Developing Limbo-Prefrontal System in Animals: Implications for Human Psychoses?

2001 ◽  
Vol 12 (1) ◽  
pp. 8-14
Author(s):  
Gertraud Teuchert-Noodt ◽  
Ralf R. Dawirs
Keyword(s):  
Prefrontal Cortex ◽  
Mental Disorders ◽  
Dentate Gyrus ◽  
Cognitive Functions ◽  
Experimental Approach ◽  
Regulatory Mechanisms ◽  
Hippocampal Dentate Gyrus ◽  
Non Invasive ◽  
Invasive Method ◽  
Activity Dependent

Abstract: Neuroplasticity research in connection with mental disorders has recently bridged the gap between basic neurobiology and applied neuropsychology. A non-invasive method in the gerbil (Meriones unguiculus) - the restricted versus enriched breading and the systemically applied single methamphetamine dose - offers an experimental approach to investigate psychoses. Acts of intervening affirm an activity dependent malfunctional reorganization in the prefrontal cortex and in the hippocampal dentate gyrus and reveal the dopamine position as being critical for the disruption of interactions between the areas concerned. From the extent of plasticity effects the probability and risk of psycho-cognitive development may be derived. Advance may be expected from insights into regulatory mechanisms of neurogenesis in the hippocampal dentate gyrus which is obviously to meet the necessary requirements to promote psycho-cognitive functions/malfunctions via the limbo-prefrontal circuit.

The methodology of experimental research of the feed components extrusion process in order to improve its energy performance

2020 ◽  
pp. 147-152
Author(s):  
E. M. Ratnikov ◽  
D. O. Milko
Keyword(s):  
Experimental Studies ◽  
Energy Performance ◽  
Extrusion Process ◽  
Mathematical Methods ◽  
Screw Extruder ◽  
Mathematical Planning ◽  
Factors Affecting ◽  
Extrusion Processing ◽  
Definition Of

Annotation Purpose. Development of a program and methods for conducting experimental studies of the extrusion process with the definition of parameters and modes of operation of the extruder to improve its energy performance. Methods. Methods of mathematical statistics, synthesis, analysis, description and modeling were used. Results. The application of mathematical methods, in particular mathematical planning, reduces the number of experiments several times, and allows to evaluate the role of influencing factors, obtain a mathematical model of the process and determine the optimal conditions for its parameters and modes, etc. Conclusions. The methodology for experimental studies of a screw extruder is presented with the necessary equipment and methodology for processing the obtained experimental data. A mathematical method of planning, which reduces the number of experiments several times, allows us to evaluate the role of factors affecting productivity and energy intensity is presented. Keywords: extruder, auger, nutrients, research methodology, extrusion, processing, feed.

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