scholarly journals Genetic polymorphisms of leptin and leptin receptor genes in relation with production and reproduction traits in cattle.

1970 ◽  
Vol 60 (4) ◽  
Author(s):  
Anna Trakovická ◽  
Nina Moravčíková ◽  
Radovan Kasarda

Leptin and leptin receptor genes are considered as production traits markers in dairy or beef cattle. The aim of this study was to verify the associations of polymorphisms in bovine LEP and LEPR genes with production and reproduction traits in Slovak Spotted and Pinzgau cows. Long-life production was evaluated: milk, protein, and fat yield and reproduction traits: age at first calving, calving interval, days open, and insemination interval. In total, 296 blood samples of Slovak Spotted and 85 hair roots samples of Pinzgau cows were analyzed. In order to detect LEP/Sau3AI (BTA 4, inron 2) and LEPR/T945M (BTA 3, exon 20) genotypes PCR-RFLP method was used. In Slovak Spotted and Pinzgau cows allele frequencies were 0.838/0.162 and 0.694/0.306 for A and B LEP variants, and 0.954/0.046 and 0.912/0.088 for C and T LEPR variants, respectively. For testing the associations between SNPs LEP/Sau3AI and LEPR/T945M and evaluated traits, the General Linear Model procedure in SAS Software was used. Statistical analysis showed that SNP LEP/Sau3AI significantly affected milk, protein and fat yield (P

1988 ◽  
Vol 68 (1) ◽  
pp. 299-303
Author(s):  
P. G. SULLIVAN ◽  
J. W. WILTON ◽  
B. J. VAN DOORMAAL

Canadian red and white (RW) and black and white (BW) Holsteins were compared for several production traits based on genetic evaluations of 32 RW and 883 BW bulls, and performance data of 4161 RW and 8691 BW cows. Differences (P < 0.05), favoring BW, were observed for milk and milk fat yield of cows, and for milk fat and milk protein yield evaluations of bulls. There was, however, a large genetic overlap between the populations for all traits studied. Pleiotropic effects associated with the color gene were not detected as being important. Phenotypic trends for milk yield, milk fat yield, and milk fat percent were significantly greater for BW than RW cows (P < 0.01). Genetic trends were greater for RW cows, though not significantly (P > 0.05). Key words: Dairy production, genetic trends, Holstein (red and white), Holstein (black and white)


Author(s):  
Memis Ozdemir ◽  
Mehmet Topal ◽  
Vecihi Aksakal

Progress in genetic selection in livestock can be increased by marker asisted selection. The identification of favorable genetic markers is one of the most important stages in marker-asisted selection. In this study, it was aimed to determine the effects of the bGH/AluI and Pit-1/HinfI polymorphisms on the production traits of organic reared cows. Genotyping was performed on total 245 Holstein cows, n=181 for Pit-1 gene and n=186 for bGH gene. Milk yields and some reproduction traits analyzed by analysis of variance using the general linear model procedure, and 703 production records from cows were used to. The results showed that neither the Pit-1/Hinf I nor bGH/Alu I polymorphisms affect the tested milk traits (p>0.05).


2011 ◽  
Vol 49 (No. 4) ◽  
pp. 131-136
Author(s):  
D. Vaněk

The purpose of the paper was to analyse the effect of the level of milk yield and breeding value on reproduction of Czech pied cows. In the study of cows that calved in the period 1999&ndash;2001 the results for 41 357&nbsp;cows from the central database were used analytically. The study was focused on the following traits: breeding value of the father of the cow for kg of milk, breeding value of the mother of the cow for kg of milk, the cow&rsquo;s milk yield in the 1st to the 3rd lactation, and reproduction traits after the 1st and 2nd calving. To determine the effect of the breeding value of the father or mother of the cow on reproduction traits of daughters the test cows were divided into 3 groups depending on the BV of the parents. The results were processed by multifactor analysis of variance using the CORR and GLM procedures of the SAS statistical program, v. 8.1., and the model with fixed effects for the calculation itself. The results of the study show a negative correlation between the level of the milk yield of cows and their reproduction. It may be stated that the increased milk yield decreases reproduction traits characterised by the extension of days open and calving interval. The estimated correlation between the milk yield and the days open was r = 0.38 for milk yield, r = 0.32 for fat yield, and r = 0.25 for protein yield. A similar correlation between the level of milk yield and the days open was also found in other calving intervals. &nbsp;


1969 ◽  
Vol 60 (4) ◽  
pp. 540-550
Author(s):  
J. K. Camoens ◽  
R. E. McDowell ◽  
L. D. VanVleck ◽  
J. D. Rivera Anaya

Records of high grade or purebred Holsteins in 62 herds on DHIA recording in Puerto Rico were used to determine phenotypic correlations of lactation length, days dry prior to lactation, days open during lactation, and interval from previous parturition (calving interval) to lactation, milk and fat yields, and fat percent. Both milk and fat yields had a significant (P < .05) positive phenotypic correlation with lactation length, calving interval, and days open (0.178 to 0.658), hut fat percent had a low relation to these traits (-0.023 to +0.014). Lactation length, dry period, days open, and calving interval were regressed on milk yield, fat yield, and fat percent. The combined contribution of these variables to variation in milk yield was 44.4%. Days open, days dry, and calving interval accounted for only 13.4% of the variation in milk yield. Days dry and days open together accounted for 9.6% of the variation, and days dry, plus calving interval, made up 6.0%, of the variation. The values for fat yield were slightly lower but followed a similar pattern as for milk yield. The four variables combined contributed only 0.23% to the variance in fat percent. Total milk yield and fat yield were inf1uenced by lactation length, calving interval, and days dry in descending order of magnitude. Days open had comparatively little influence on either milk or fat yields. Length of dry period influenced fat percent more than any other variable but to little extent. Since the majority of the variation in milk and fat yields attributed to the four variables was due to lactation length, it appears that in Puerto Rico selection with emphasis on lactation yields is unlikely to decrease fertility.


2008 ◽  
Vol 53 (No. 6) ◽  
pp. 238-246 ◽  
Author(s):  
E. Hradecká ◽  
J. Čítek ◽  
L. Panicke ◽  
V. Řehout ◽  
L. Hanusová

: We analysed the relations of estimated breeding values (EBV) of 315 German Holstein sires to their genotypes in growth hormone gene (<i>GH1</i>), growth hormone receptor gene (<i>GHR</i>) and acylCoA-diacylglycerol acyltransferase 1 (<i>DGAT1</i>). The strong relation of <i>DGAT1 K232A</i> to the estimated breeding values for milk production traits has been confirmed, when allele <i>DGAT1<sup>K</sup></i> was connected with higher milk fat yield, milk fat and milk protein content, while allele <i>DGAT1<sup>A</sup></i> increased milk yield and milk protein yield. The effect of <i>DGAT1</i> genotype explained from 4.70% of variability of EBVs for fat yield to 31.90% of variability of EBVs for fat content. The evaluation of <i>GH1</i> 127 Leu/Val and <i>GHR</i> 257 SNP polymorphisms did not reveal an association of their polymorphism with EBVs for milk production traits, except the EBVs of <i>GHR<sup>G</sup>/GHR<sup>G</sup></i> homozygotes for fat yield, which were significantly lower. The effect of <i>GH1</i> or <i>GHR genotype explained only a negligible portion of variability of EBVs (<i>R</i><sup>2</sup> < 1.00% in most cases).


1969 ◽  
Vol 60 (4) ◽  
pp. 551-558
Author(s):  
J. K. Camoens ◽  
R. E. McDowell ◽  
L. D. VanVleck ◽  
J. D. Rivera Anaya

Variance components were estimated for herd, sire, and cow effects with a three-way nested model, using unadjusted and adjusted records for age and seasonal difference from 62 herds on DHIA recording in Puerto Rico. The cows calved from 1967 to 1973. They were high grade and purebred Holsteins imported from Canada or the United States or progeny of bulls and semen from the two countries. The percentages of the total variance for milk yield were 18.7, 4.9, and 40.8% for herd, sire, and cow, respectively. The percentages for fat yield were similar. These, plus the component for lactation length and days open, were in the range reported from temperate regions. The variance components of fat percent were similar to that of temperate regions for herd ( 14.9%) and cow (54.1%), but the sire component was negative, indicating factors yet unidentified that influenced this trait. Total variances for milk and fat yields indicated sufficient variability to permit selection. Estimates of heritability and repeatability for milk yield, fat yield, fat percent, lactation length, and days open computed from the sire and cow variance components were consistent with those reported from the temperate regions. The estimates indicate there was no loss of genotypic variance in the tropical environment. It appears that genotype exerts as much influence on production in Puerto Rico as elsewhere.


Author(s):  
Małgorzata Szewczuk ◽  
Sławomir Zych ◽  
Ryszard Chaberski

The objective of this study was to evaluate the relationship between the polymorphism within GHRH gene (GHRH/HaeIII) and milk production traits for Polish Holstein-Friesian using PCR-RFLP technique for genotyping. The molecular background of this mutation was defined as the A→C transversion at the intron 2. A total of 220 cows were examined. The following frequencies were established: 0.0227 for genotype AA, 0.3227 for AB, and 0.6546 for BB; 0.1841 for the allele GHRHA and 0.8159 for GHRHB. A highly significant association was found between the GHRH/HaeIII polymorphism and milk performance. The BB-genotype cows were characterised by a higher fat yield and percentage (P ≤ 0.01).


2018 ◽  
Vol 61 (2) ◽  
pp. 197-206 ◽  
Author(s):  
Memis Ozdemir ◽  
Sinan Kopuzlu ◽  
Mehmet Topal ◽  
Omer Cevdet Bilgin

Abstract. Many researchers who have studied the relationships between milk protein polymorphisms and some yield traits in dairy cattle have reported incompatible results. In this study, in order to examine the overall relationships between milk protein genes known as major genes (CSN1S1, CSN2, CSN3, and BLG) and some yield traits (daily milk yield, lactation milk yield, fat yield, fat content, protein yield, and protein content), a meta-analysis was performed using some genetic models reported in the results of previous studies on cattle. The results suggest that the relationships of major milk protein genes with other factors should be studied using the codominant genetic model in general. Relationships among some CSN3 genotypes and fat yield, fat content, and protein content, and relationships between some BLG genotypes and daily milk yield, fat content, protein yield, and protein content were significant (P<0.05). No significant (P>0.05) relationships were found between these genotypes and other milk production traits. In addition, no significant (P>0.05) relationships between the CSN1S1 and CSN2 genotypes with the milk production traits examined were observed.


2014 ◽  
pp. 4116-4129 ◽  
Author(s):  
Juan Zambrano A ◽  
Julián Echeverri Z ◽  
Albeiro López-Herrera

ABSTRACTObjective. To determine the associations of BoLA DRB3.2 alleles present in Holstein and BON x Holstein cattle to production and milk quality traits in a dairy herd of Antioquia, Colombia. Materials and methods. Ninety-one cows, 66 Holstein and 25 BxH, were genotyped for the BoLA DRB3.2 gene, through PCR-RFLP technique. Furthermore, the association of the alleles of the gene BoLA DRB3.2 with milk yield (PL305), fat yield (PG305), protein yield (PP305) fat percentage (PGRA) and protein percentage (PPRO) were determined, using a general linear model. Results. Twenty-seven BoLA DRB3.2 alleles were identified; the most frequent alleles in Holstein were: BoLA DRB3.2*23, 22, and 24 with frequencies of: 0.159, 0.129, and 0.106, respectively and the most frequent alleles in BxH were: BoLA DRB3.2*23, 24 and 20 with frequencies of: 0.20, 0.140, and 0.120, respectively. Associations of BoLA DRB3.2 alleles with production and milk quality traits were also determined. In Holstein cows the BoLA DRB3.2*36 allele was associated with low PL305 (p≤0.01), high PGRA in multiparous cows (p≤0.05) and high PG305 in primiparous cows (p≤0.01). The BoLA DRB3.2*33 allele was associated with increased in the PPRO in multiparous cows (p≤0.01). In BXH cows only the BoLA DRB3*19 allele was associated with high PGRA (p≤0.05). Conclusions. The gene BoLA DRB3.2 shows high polymorphism in both groups; Holstein and BxH and some of its allelic variants were associated with production and milk quality traits


2012 ◽  
Vol 55 (4) ◽  
pp. 307-314 ◽  
Author(s):  
I. Anton ◽  
K. Kovács ◽  
G. Holló ◽  
V. Farkas ◽  
F. Szabó ◽  
...  

Abstract. The objective of this study was to estimate the effect of acylCoA-diacylglycerol-acyltransferase 1 (DGAT1), leptin and thyroglobulin (TG) loci on the milk fat, milk protein and milk yield in Holstein Friesian, Jersey and Hungarian Simmental cows. Leptin and DGAT1 genotypes were determined by qPCR assay, while TG genotypes were identified using the polymerase chain reaction-restriction fragment length polymorphism technique (PCR-RFLP). DGAT1 GC/GC cows had the highest 305-day milk yield values. Difference between AA/AA and GC/GC genotypes was significant (P<0.05). Leptin CC animals produced significantly higher 305-day milk protein percent values (P<0.05) than other genotypes in Hungarian Simmental breed. At TG locus TT cows showed the highest 305-day milk fat percent values, although differences between genotypes proved to be significant (P<0.05) only in Jersey breed.


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