Animated Video in Teaching Reading Comprehension Viewed from the Students’ Reading Interest

The purposes of this study are to find out whether (1) animated video is effective in teaching reading comprehension, (2) students with high reading interest have better reading comprehension achievement than those with low reading interest, and (3) there is an interaction between the teaching media and the students’ reading interest in teaching reading comprehension. This study is experimental research. The population of this study is the students of MTs Negeri Prambanan. Two classes were taken as the sample, and the sampling technique used was cluster random sampling. This study applied tests and a questionnaire in collecting the data and Kolmogorov-Smirnov formula, One Way ANOVA, and multifactor analysis of variance in analyzing the data. Based on the result of data analysis, the research findings are: (1) animated video is effective in teaching reading comprehension of the students in MTs Negeri Prambanan (Fobtain = 7.60, Sig. Value 0,05); (2) the students in MTs Negeri Prambanan with high reading interest have better reading comprehension achievement than those with low reading interest (Fobtain = 9.19, Sig. Value 0,05); (3) there is an interaction between the teaching media and the students’ reading interest in teaching reading comprehension of the students in MTs Negeri Prambanan (Fobtain = 6.15, Sig. Value 0,05). Based on these research findings, it can be concluded that animated video is effective in teaching reading comprehension of the students of MTs Negeri Prambanan. It brings improvement to the students’ reading comprehension achievement.

Sensitivity Study of the Computational Parameters for the Deformation of Homogeneous Earth Dams

The deformation of dams has always been the focus of dam safety research. To more accurately study the effect of the Duncan–Chang model on the deformation of homogeneous Earth dams, this paper simulates the displacement variation of a homogeneous Earth dam through the finite element method based on the Duncan–Chang E-B model. The sensitivity of the Duncan–Chang E-B model parameters and the dam material density on the displacement of a homogeneous earthen dam in Gansu Province, China, were investigated using single-factor and multifactor analysis methods. The results show that the displacement variation of the dam during the completion and operation periods is consistent with the general rule for Earth and rock dams; the three parameters R f , φ 0 , and Δ φ are more sensitive to dam deformation; and the three parameters m , n , and K are less sensitive to dam deformation.

Application of the Results of Chromatic Technology Data Interpretation in Seismogeological Modeling of Continental Deposits of Western Siberia on the Example of the Zapadno-Ust-Balykskoe Field

The aim of the article is creation a conceptual model based on the data of chromatic technology data interpretation to improve the quality of forecasting potentially productive areas of occurrence of Jurassic formations of the Tyumen formation, as well as ranking the deposit by priority zones based on multifactor analysis. The article uses methods of complex reinterpretation of seismic and geological-geophysical materials in order to search for and localize highly productive zones of the Tyumen formation formations. The result of the work is a detailed strategy formed: the exploration and production drilling of the J2 formation. A significant increase in the expected ability of potentially productive objects in the inter-well space in the conditions of complex reservoirs due to modern processing technologies and interpretation was noted. The prospects of translating the methodology for optimizing the development of Jurassic objects of the Tyumen Fm at the fields of Slavneft-Megionneftegaz and other assets of Russian oil producing companies are revealed.

Old age and other factors associated with salivary microbiome variation

Background Many factors can contribute to the exact makeup of the salivary microbiome. Differences in the oral microbiome occur with old age, which may be due to oral conditions and diseases associated with old age, such as edentulism, as well as other unknown causes. Methods The salivary microbiome was sampled in patients from a large urban clinic. For all subjects age, gender, periodontal status, caries status, presence of edentulism, medications, and tobacco usage were recorded. Multifactor analysis was used to study variation in salivary microbiome profiles linked to these factors. Results In the population sampled, there were significantly higher numbers of edentulous subjects, and increased levels of polypharmacy found with aging. Large differences in alpha diversity and beta diversity of the salivary microbiome in the old age group were largely linked to edentulism. However, multivariable analysis revealed, even after adjusting for differences in edentulism, polypharmacy, tobacco usage, periodontal disease, caries level, and gender, that old age itself was associated with lower levels of taxa Porphyromonas endodontalis, Alloprevotella tannerae, Filifactor alocis, Treponema, Lautropia Mirabilis and Pseudopropionibacterium sp._HMT_194. Surprisingly, of these taxa, most were ones known to reside on or near tooth surfaces. Conclusions Another factor or factors beyond edentulism, polypharmacy and periodontal disease play a role in the differences seen in oral microbiome with old age. The nature of this factor(s) is not known.

Serum Levels of Vitamin D, Retinol, Zinc and CRP in Relation To Obesity Among Children and Adolescents

Background: The aim of this study was to examine the possible association between serum micronutrients (vitamin D, retinol, Zinc ), C-reactive protein (CRP) and obesity among children and adolescents. Methods: Weight and height were measured and serum 25-hydroxy vitamin D, serum retinol, serum Zinc and CRP were measured in 2818 children and adolescents(6-17 years of age), using the data of 10 investigation sites in Zhejiang Province. The difference of micronutrients (vitamin D, retinol, zinc), CRP among different BMI status were explored by ANOVA and chi-square test. The associated factors of micronutrients and CRP of overweight and obesity were explored by multifactor analysis.Results: There were significant differences between male students and female students on BMI, 25(OH)D3, CRP, and there were significant differences between children and adolescents and between students living in urban area and rural area on BMI, 25(OH)D3, retinol, zinc(p < 0.05). There were significant differences on 25(OH)D3 and CRP level, and on retinol level among children and adolescents with different nutritional conditions (p < 0.05). In multifactor analysis, we found that gender(OR=0.626, 95%CI:0.486-0.806), living area (OR=0.666, 95%CI:0.515-0.860), age group(OR=0.894, 95%CI:0.856-0.934), high CRP concentration (OR=1.084,95%CI:1.046-1.122) and appropriate retinol level (OR=1.536, 95%CI:1.185-1.991) were associated with students with obesity. Conclusion: Gender, living area, age group, CRP concentration and vitamin A status were associated with children and adolescents with overweight and obesity. More attention in the intervention of overweight and obesity should be paid to boys living in urban areas, and high serum CRP and retinol level should also be concerned.

Multifactorial Evaluation of Atenolol, Caffeine, Carbamazepine and Ibuprofen on Raphidocelis subcapitata and Chlorella vulgaris

Micropollutants in aquatic resources have raised global concerns regarding the conservation of ecosystems. Although they are usually found in the environment at trace concentrations to a maximum of several µg/L, it is still necessary to address the potential risks these pollutants may represent to organisms. A multifactor analysis was conducted using two algae as bioindicators. Four different pharmaceuticals were chosen based on their occurrence in domestic wastewaters and persistency after biological treatment processes ranging from 1/8th to four-fold representative environmental concentrations over 96 h exposure. The present multifactor analysis evaluated cell size, photosynthetic capacity and growth rate. These data were later combined into a simplified single entity: “the index effect”. The results obtained showed that, even at concentrations below the environmentally relevant concentrations (ERC), the pharmaceuticals’ residues (PRs), caused a cellular behavioural variation in both organisms. In addition, the algae cultures’ response to exposure to these stressors was generally dependent on the concentration over time. By examining four different PR over three different characteristics of two types of algal bioindicators, this work covers significant and specific responses on the algae exposure cycle. This is unique research since most studies do not consider multiple parameters in the assessment of the environment risk for bioindicators.

Hp-Positive Chinese Patients Should Undergo Colonoscopy Earlier and More Frequently: The Result of a Cross-Sectional Study Based on 13,037 Cases of Gastrointestinal Endoscopy

BackgroundIn China, the prevalence and mortality of colorectal cancer (CRC) have always been high, and more than 95% of CRC cases have evolved from colorectal polyps (CPs), especially adenoma. Early detection and treatment of CPs through colonoscopy is essential to reduce the incidence of CRC. Helicobacter pylori (Hp) is regarded as a risk factor for gastritis and gastric cancer and may also be a risk factor for CPs and CRC. However, few studies based on vast clinical cases exist in China to clarify whether Hp is a risk factor for CPs and CRC, and whether Hp-positive patients need to undergo colonoscopy checks earlier. This article attempts to make up for that deficiency.MethodThis cross-sectional study was conducted based on 13,037 patients without a treatment history of Hp who underwent their first gastroscopy and colonoscopy simultaneously at The First Affiliated Hospital of Zhejiang Chinese Medical University from January 2018 to December 2019. Pearson χ2 test and logistic regression were used to determine whether Hp is a risk factor for CPs and CRC. Multifactor analysis of variance was used to define the impact of Hp on CPs prevalence with different ages, sexes.ResultsFor Chinese individuals, Hp is a risk factor for CPs and CRC. The odds ratio (OR) value are 1.228 (95% CI, 1.130 to 1.336) and 1.862 (95% CI 1.240-2.796), respectively. Hp-positive patients have a higher probability of multiple or large intestinal polyps. However, Hp infection does not increase the incidence of adenomas, nor does it affect the pathological type of adenomas. The OR of Hp on the risk of CPs was 1.432 (95%CI 1.275-1.608) for males but increased to 1.937 (95%CI 1.334-2.815) for those aged 35 to 40. For females, the results were similar.ConclusionsFor the Chinese, Hp is a risk factor for CPs and CRC (OR&gt;1); the infection of Hp increased CPs risk in Chinese of all ages, especially aged 35-40, suggesting that Hp-positive patients should undergo colonoscopy frequently.

AGE AS ONE OF THE IMPORTANT CRITERIA OF PROSTATE CANCER DIAGNOSTIC

Дифференциальная диагностика рака предстательной железы (РПЖ) в настоящее время требует поиска новых, более эффективных подходов с учетом многофакторного анализа. Одним из таких факторов является возраст пациента. У мужчин старше 45 лет наблюдают выраженные инволютивные изменения тканей предстательной железы, что важно учитывать при оценке морфологических и лабораторных критериев при РПЖ. Цель работы оценить возрастные изменения объема предстательной железы и лабораторных показателей анализа крови при РПЖ. У 632 пациентов 42-88 лет методом трансректального УЗИ (ТРУЗИ) оценивали объемные показатели предстательной железы и уровень простатспецифического антигена (ПСА) и 2-про-ПСА в крови. С возрастом наблюдают повышение плотности транзиторной, периферической и центральной зон предстательной железы. Это коррелирует с повышением частоты выявления РПЖ. Уровень ПСА и 2-про-ПСА в крови у пациентов с РПЖ повышается при переходе от среднего к старческому возрасту в 1,4-2,8 раза. Таким образом информация, полученная в ходе оценки объемных показателей предстательной железы по данным ТРУЗИ и лабораторного исследования при постановке диагноза РПЖ, должна учитывать возраст пациента. At this moment differential diagnostic of the prostate cancer (PC) needs the new, more effective ways with regard of multifactor analysis. One of this factor is patient s age. Men older than 45 years old have expressed involution changes of prostate tissues. This fact must be take into account in valuation morphologic and laboratory criteria s in PC. The goal of the investigation is to take into account age-related changes of the prostate volume and laboratory criteria of blood analysis in PC. 632 patients in age from 42 to 88 years old were exanimated by trans rectal ultrasound examination (TRUS) method (volume parameters of the prostate) and by levels of prostate-specific antigen (PSA) and (-2) pro-PSA in blood. The increase of patient s age correlated with increase of the density of transient, peripheral and central zones of prostate. It correlates with the probability of the frequency of PC verification. Levels of PSA and 2-pro-PSA in blood of PC patients increase during the transition from middle to elderly age in 1,4-2,8 times. Thus the information, which was obtained during the examination of volume prostate characteristics by TRUS method and laboratory diagnostic of PC, must take to account patient s age.

Clinical Predictors of Occurrence of Ventricular Tachyarrhythmias in Patients with Reduced Left Ventricle Ejection Fraction. Results of Single-Center Prospective Study

Aim To evaluate the diagnostic significance of clinical and demographic parameters for predicting a 2-year probability of ventricular tachyarrhythmias (VT) in patients with chronic heart failure and reduced left ventricular ejection fraction (CHFrLVEF).Material and methods This single-center, prospective cohort study included 175 patients with CHFrLVEF who were implanted with a cardioverter defibrillator (CD). The endpoint was a CD-detected episode of VT. Patients were followed up for 2 years with visits at 3, 12, and 24 months after CD implantation.Results The primary endpoint was observed in 43 (24.4 %) patients at an average of 20.9 months (95 % confidence interval (CI), 20–21.9). The 2-year risk of fatal ventricular arrhythmias increased with detection of unstable VT (one-factor analysis, odds ratio (OR), 4.2; 95 % CI, 1.1–16.5; р=0.041; multifactor analysis, OR, 6.3; 95 % CI, 1.5–26.3; р=0.012) and with ischemic CHFrLVEF origin (one-factor analysis, OR, 2.2; 95 % CI, 1.1–4.5; p=0.021; multifactor analysis, OR, 2.5; 95 % CI, 1.2–5.1; р=0.018). In the presence of any type of atrial fibrillation (AF) in patients with non-ischemic CHFrLVEF, the probability of VT increased threefold (one-factor analysis, OR, 2.97; 95 % CI, 1.02–8.8; р=0.047; multifactor analysis, OR, 3.5; 95 % CI, 1.1–10.9; р=0.032).Conclusion The presence of ischemic heart disease and unstable VT paroxysms can be included in the number of important clinical predictors of VT in patients with CHFrLVEF. In patients with non-ischemic CHF, the presence of AF is associated with a high risk of VT.