scholarly journals Strategies for the Discovery and Development of Anti-Diabetic Drugs from the Natural Products of Traditional Medicines

2013 ◽  
Vol 16 (2) ◽  
pp. 207 ◽  
Author(s):  
Ji-Ming Ye ◽  
Stanley M.H.
Keyword(s):  
Natural Products ◽  
Traditional Medicine ◽  
Biomedical Research ◽  
Collaborative Research ◽  
Point Of View ◽  
The West ◽  
Computer Aided Drug Design ◽  
Materia Medica ◽  
Traditional Medicines ◽  
The Past

This review discusses issues largely from the biological point of view about the targeted approaches for the use of natural products for the discovery of anti-diabetic drugs in collaboration with medicinal chemists and computer-aided drug design. A major thrust of this review reflects the collaborative research of four institutions: RMIT University (Australia), Garvan Institute of Medical Research (Australia), Shanghai Institute of Materia Medica of the Chinese Academy of Science (China) and Sun-Yat Sen University (China) in the past eight years. By joining forces of biomedical research in diabetes and medicinal chemistry with a focus on traditional medicine, they are trying to bridge the West (the latest research discoveries in biomedical research) with the East (traditional medicine) to step forward in drug discovery from natural products. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

On rhodonite and tephroite from Treburland manganese mine, Altarnun, Cornwall; and on rhodonite from other localities in Cornwall and Devonshire

1946 ◽  
Vol 27 (194) ◽  
pp. 221-235 ◽  
Author(s):  
Arthur Russell
Keyword(s):  
Sedimentary Rocks ◽  
Point Of View ◽  
Contact Metamorphism ◽  
Geological Survey ◽  
The West ◽  
The Past ◽  
Manganese Deposits ◽  
The Many

Of the many small manganese deposits which have in the past been worked in both Cornwall and Devonshire that of Treburland is from the mineralogical point of view by far the most remarkable, its especial interest being due to the variety of minerals which it has afforded and to the fact that it and one other are the only manganese deposits in the west of England which are known to lie on the contact of igneous and sedimentary rocks and which have consequently been vitally affected by contact metamorphism.The following observations are based on frequent visits to the spot since the year 1906, when I first stumbled across the locality, which, strange to say, has only received very cursory mention by the Geological Survey and has altogether escaped mention in mineralogical literature.

scholarly journals ANALYSIS OF COLLABORATIVE RESEARCH IN ARCHITECTURE AND PSYCHOLOGY OF THE LATE TWENTIETH-EARLY TWENTY-FIRST CENTURY

Articult ◽  
2020 ◽  
pp. 137-148
Author(s):  
Evgenia I. Vinogradova ◽  
◽  
Evgeny V. Kilimnik ◽  
Keyword(s):  
Collaborative Research ◽  
First Century ◽  
The West ◽  
The Past ◽  
Relevant Today ◽  
Early Twenty ◽  
Late Twentieth ◽  
The Individual ◽  
Relationship Of ◽  
The Relationship

The article analyzes the work of Western and Russian scientists, conducted in the past three decades, on the relationship of psychology and architecture. It is shown that in the West, the neuropsychological aspects of the relationship of psychology and architecture are studied thanks to modern neurobiological equipment, while in Russia there is a clear gap between the representatives of neuroscience, their technical support, and the architectural scientific community. As a result of the analysis conducted in the article, it is concluded that two research blocks can be distinguished. The first of them highlights the relationship between the psyche of the viewer and architecture. This may include research, both revealing the features of the perception of objects, and the influence of an architectural object on the viewer. Another block of research is connected with the psyche of the architect: and here the features of the design process itself are examined, as well as the influence of the personality of the architect on the features of the architectural object. It is concluded that the topic of reflecting the individual or individually-typological psychological characteristics of the personality of an architect in a specific architectural work remains undeveloped both in the West and in Russia, although it is extremely relevant today.

scholarly journals The historian in prosecutor’s garb, or, The idea of legal and/or moral responsibility in historiography: The Example of Communism.

AmeriQuests ◽  
2012 ◽  
Vol 10 (1) ◽  
Author(s):  
Marc Angenot
Keyword(s):  
Moral Responsibility ◽  
Point Of View ◽  
Historical Research ◽  
Black Book ◽  
The West ◽  
Source Criticism ◽  
Legal Principles ◽  
The Past ◽  
The Press ◽  
Real Socialism

Law and historiography share several fundamental paradigms: the search for truth based on facts from the past; investigation; the presentation of “exhibits;” testimony and the evaluation of witnesses (according to the kind of jurisprudence that forms source criticism); the use of “pieces of evidence,” etc. If it is true that “legal principles cannot be transferred as-is into historical research,” that the demands in terms of evidence are not of the same nature, and that—and this is a decisive difference, but one that is not always observed, far from it, and it’s precisely this difference that will be the theme of my reflections today—the historian is not supposed to, having reconstructed the facts, regardless of how incriminating they are, pass judgement on, nor present a prosecutor’s charge against (nor plea for the acquittal of) figures from the past.With a belated but exceptionally violent spurt, the 1997 publication of The Black Book of Communism in France rekindled the long-lasting debate on the role and record of communism, mobilizing the press as a whole and every essayist in sight, with no signs that controversy is about to die down. Un pavé dans l’histoire, by Pierre Rigoulot and Ilios Yannakakis, recounts the first months of the polemic surrounding the “memory of communism” in France, positioning itself from the accusatory point of view of the book’s contributors. Several years later, the collective text Du passé faisons table rase! introduced French readers to the contrasting receptions The Black Book’s translations met in all of Europe’s countries and languages: very favourable in the East, reticent in the West—with intellectual France, as always, a clear exception, diverging from the countries who had known “real socialism,” despite the reluctance of a rearguard of prudently recycled apparatchiki who had preferred not to “stir up the mud” of the past.

Ethnobotany

2022 ◽  
pp. 270-291
Author(s):  
Akash ◽  
Navneet ◽  
Bhupendra Singh Bhandari ◽  
Surendra Singh Bisht ◽  
Dalip Kumar Mansotra
Keyword(s):  
Natural Products ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Medicine ◽  
Recent Time ◽  
Ethnomedicinal Plants ◽  
Traditional Medicines ◽  
Relationship Of ◽  
The Relationship

Traditional medicines and natural products from ethnomedicinal plants have great significance in recent time. Various forms of medicines like Ayurveda, traditional Chinese medicine, kampo, Unani, have been plasticising in recent days due to their effectiveness against various human ailments and also have blossomed into the regulated systems of traditional medicine. This chapter reviews the relationship of plants and humans, along with their cultural relationship and role of the traditional medicines, by exploring the methodologies and various concepts for the discovery of various drugs. Further, this will also illustrate traditional medicines that have their incomparable advantages over the modern allopathic medicines.

scholarly journals Celebrating ‘Indian's’ in Shashi Deshpande’s The Dark Holds No Terrors and The Roots and Shadows

2021 ◽  
Vol 9 (3) ◽  
pp. 72-82
Author(s):  
K. Maheswari
Keyword(s):  
Cultural Values ◽  
Education System ◽  
Point Of View ◽  
Human Beings ◽  
The West ◽  
Value System ◽  
Indian Women ◽  
The Past ◽  
New Education ◽  
The Impact

The aim of this paper is an attempt that Indian cultural values should be revised meticulously and   accurately leaving behind western impact and the paper rides on a new pride, as a revival of inspiration, a recuperation from centuries of British domination of India in which Hindu dignity was systematically undermined through the Macaulay education system and the invasion of Mogul. Values are what human beings live by. The value-system of any given culture determines the sense of fulfillment and degree of happiness of its members. Indian value system had been misinterpreted from the point of view of the west and imposed  on the psyche of Indian women  through new education. The new education has gradually made her conscious of futility or emptiness of the various long-preserved notions and taboos about the woman, and she has started opposing and breaking them. And this crusade at times makes her feel alone  and alienated. Their conscious had been colonized according to the impact of western. Nevertheless, it is high time that contemporary Indian women are in position to realize their roots, meaning of life and great value system of India. Hence, tradition is the best of the past that has been carried forward for the future.

Re-Islamization of the West African Ummah A Model for Tajdid?

1987 ◽  
Vol 4 (2) ◽  
pp. 209-228
Author(s):  
Abdur Rahman I. Doi
Keyword(s):  
West Africa ◽  
Personal Development ◽  
West African ◽  
Point Of View ◽  
Muslim World ◽  
Sahara Desert ◽  
The West ◽  
The Past ◽  
Islamic Civilization

IntroductionHuman development, from the Islamic point of view, can be achieved onlyby following the footsteps of the Prophet (SAAS). The nearer one comes toimbibing the Message of the Quran, Sunnah, and Shari’ah in one’s life, themore humanly developed one becomes, because personal development in Islamis measured by one’s refinement in living this Message. The more refinedand developed are the persons in a community, the better will be their cultureand civilization.As long as Muslims continued moulding their life according to the Shari‘ah,their civilization in Medina, Baghdad, Andullis, Constantinople, and Delhiflourished. The decline and fall of Islamic civilization came when Muslimsstarted paying mere lip service to the formula of faith and departing fromthe spirit and purposes of the Shari‘ah. This was the unfortunate phenomenonthroughout the Muslim world. Fortunately, the rightly inspired people roseto bring back the erring Muslims to the path of the Shari’ah. This paper seeksto present an assessment of the dynamics used by a Mujaddid (a promoterof Tajdid or revival) of West Africa to re-Islamize a society that had sunkinto the abyss of confusion.Islam in West AfricaWest Africa, situated south of the Sahara desert, and which the Arabhistorians called Bilad al Sudan, has witnessed in the past, many Islamicempires, e.g., Ghana, Mali, Songhai, and Bornu, the last of which was theSokoto Caliphate. It emerged from the process of Tajdid (renewal or revival inaccordance with the Quran and Sunnah)’ which was started by Shehu(Shaikh) ‘Uthman Danfodio (1754-1817) in 1774, and which culminated in ...

Ethnobotany

2020 ◽  
pp. 38-57
Author(s):  
Akash ◽  
Navneet ◽  
Bhupendra Singh Bhandari ◽  
Surendra Singh Bisht ◽  
Dalip Kumar Mansotra
Keyword(s):  
Natural Products ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Medicine ◽  
Recent Time ◽  
Ethnomedicinal Plants ◽  
Traditional Medicines ◽  
Relationship Of ◽  
The Relationship

Traditional medicines and natural products from ethnomedicinal plants have great significance in recent time. Various forms of medicines like Ayurveda, traditional Chinese medicine, kampo, Unani, have been plasticising in recent days due to their effectiveness against various human ailments and also have blossomed into the regulated systems of traditional medicine. This chapter reviews the relationship of plants and humans, along with their cultural relationship and role of the traditional medicines, by exploring the methodologies and various concepts for the discovery of various drugs. Further, this will also illustrate traditional medicines that have their incomparable advantages over the modern allopathic medicines.

scholarly journals Policies and Problems of Modernizing Ethnomedicine in China: A Focus on the Yi and Dai Traditional Medicines of Yunnan Province

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Zhiyong Li ◽  
Caifeng Li ◽  
Xiaobo Zhang ◽  
Shihuan Tang ◽  
Hongjun Yang ◽  
...  
Keyword(s):  
Traditional Medicine ◽  
Quality Standard ◽  
Sustainable Utilization ◽  
Materia Medica ◽  
Traditional Medicines ◽  
Industrial Base ◽  
Patent Medicines ◽  
Rare And Endangered ◽  
Wild Resources ◽  
Chinese Patent

Yunnan is a multiethnic province in southwest China, rich in Materia medica resources, and is popularly known as the kingdom of plants. Biomedicine and public health industry have been the industrial pillars of Yunnan since 2016, which is the important pharmaceutical industrial base for Dai and Yi medicine in China. This review of the Yunnan ethnic medicine industry describes some of the problems to be solved in the development of sustainable ethnomedicine in China. We investigated Chinese patent medicines (CPMs) declared as ethnomedicine on the drug instructions and identified 28 Dai patent medicines (DPMs) and 73 Yi patent medicines (YPMs) that were approved for clinical use in China. In further research, the clinical indications of these CPMs were determined, and the quality standard of medicinal materials and their usage frequencies in DPMs and YPMs were investigated. We also collected and analyzed the data on use of botanical and animal sources of medicines, the rare and endangered medicinal materials, and toxic medicines in DPMs and YPMs. The application of zootherapy in Yi traditional medicine was introduced from its abundant ancient documents and records; based on the “YaGei” theory in Dai traditional medicine, toxic medicines can be relatively safe in DPMs. However, for promoting the Yunnan traditional medicine industry, it is necessary to strengthen medical research to expand evidence-based clinical practice and balance ethnomedicine production and sustainable utilization of Materia medica resources, especially the animal sources of medicines, toxic medicines, and the protected wild resources reported in this survey. Only in this way can industrialization of ethnomedicine promote the improvement of human health.

Ultrastructure and analytical microprobe analysis of simian lung mite pigments

1986 ◽  
Vol 44 ◽  
pp. 324-325
Author(s):  
R. W. Cole ◽  
J. C. Kim
Keyword(s):  
Biomedical Research ◽  
Tissue Damage ◽  
Microprobe Analysis ◽  
Old World Monkeys ◽  
Old World ◽  
Experimental Animals ◽  
The Past ◽  
Lung Mite ◽  
Mite Infestations ◽  
Cardiopulmonary System

In recent years, non-human primates have become indispensable as experimental animals in many fields of biomedical research. Pharmaceutical and related industries alone use about 2000,000 primates a year. Respiratory mite infestations in lungs of old world monkeys are of particular concern because the resulting tissue damage can directly effect experimental results, especially in those studies involving the cardiopulmonary system. There has been increasing documentation of primate parasitology in the past twenty years.

Chelovek.RU/Человек.RU

Chelovek RU ◽  
2020 ◽  
pp. 18-53
Author(s):  
Sergei Avanesov ◽  
Keyword(s):  
Family History ◽  
Great Distance ◽  
Point Of View ◽  
The Past ◽  
Russian Philosopher ◽  
True Meaning ◽  
The Future ◽  
Pavel Florensky ◽  
The Moment

Abstract. The article analyzes the autobiography of the famous Russian philosopher, theologian and scientist Pavel Florensky, as well as those of his texts that retain traces of memories. According to Florensky, the personal biography is based on family history and continues in children. He addresses his own biography to his children. Memories based on diary entries are designed as a memory diary, that is, as material for future memories. The past becomes actual in autobiography, turns into a kind of present. The past, from the point of view of its realization in the present, gains meaning and significance. The au-thor is active in relation to his own past, transforming it from a collection of disparate facts into a se-quence of events. A person can only see the true meaning of such events from a great distance. Therefore, the philosopher remembers not so much the circumstances of his life as the inner impressions of the en-counter with reality. The most powerful personality-forming experiences are associated with childhood. Even the moment of birth can decisively affect the character of a person and the range of his interests. The foundations of a person's worldview are laid precisely in childhood. Florensky not only writes mem-oirs about himself, but also tries to analyze the problems of time and memory. A person is immersed in time, but he is able to move into the past through memory and into the future through faith. An autobi-ography can never be written to the end because its author lives on. However, reaching the depths of life, he is able to build his path in such a way that at the end of this path he will unite with the fullness of time, with eternity.

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