scholarly journals Prevalence, Intensity and Risks Involved in Helminth Infections in Domestic Mountain Pony and Balkan Donkey in Nature Park Stara Planina, Serbia

2021 ◽  
Author(s):  
Slavica Živković ◽  
Ivan Pavlović ◽  
Bojana Mijatović ◽  
Ivana Trailović ◽  
Dragiša Trailović
Keyword(s):  
Risk Factors ◽  
Helminth Species ◽  
Parasitic Helminths ◽  
Gastrointestinal Helminth ◽  
Helminth Infections ◽  
Helminthic Infections ◽  
Faecal Egg Count ◽  
Nature Park ◽  
The Mean ◽  
And Gender

Background: This study aimed to investigate the prevalence, intensity and risk factors (age and gender) promoting the intestinal helminthic infections of the Domestic mountain ponies and Balkan donkeys in Serbia. Methods: Prevalence, intensity and risk factors influencing helminth infection in horses (n=39) and donkeys (n=18) at the site of Nature Park Stara Planina, were studied from May to Sep 2015. The presence of one or several gastrointestinal helminth species was confirmed by faecal flotation in 97.43% of horses and 88.88% of donkeys included in the monitoring. The identified helminth species were Trichostrongylus axei, Strongylus edentatus, S. vulgaris, Parascaris equorum, Dictyocaulus arnfieldi and Anoplocephala magna in 84.61%, 46.15%, 5.13%, 58.97%, 94.87% and 38.46% of horses, respectively. The significant association of infection with P. equorum and sex of horses was established. (χ2=13.33, P<0.01). Results: The prevalence of parasitic helminths identified in donkeys was the following: D. arnfieldi, T. axei, Pa. equorum, S. vulgaris, A. margna and Strongyloides westeri in 55.55%, 38.89%, 27.78%, 22.22% and 22.22% of donkeys, respectively. Moreover, the mean faecal egg count was higher in donkeys (369.9 EPG - egg per gram) than in horses (250.2 EPG). The association between the age and the mean EPG was significant (P<0.05) in both equine species. Conclusion: The results of the investigation provided basic information that can be helpful for planning strategic control of nematode infection in equine population in Nature Reserves in Serbia.

scholarly journals Risk Factors for Mumps at a University with a Large Mumps Outbreak

2009 ◽  
Vol 124 (3) ◽  
pp. 419-426 ◽  
Author(s):  
Angela S. Huang ◽  
Margaret M. Cortese ◽  
Aaron T. Curns ◽  
Rebecca H. Bitsko ◽  
Hannah T. Jordan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Multivariate Analyses ◽  
Health Department ◽  
Mmr Vaccine ◽  
Large Outbreak ◽  
The Mean ◽  
And Gender ◽  
And Control ◽  
Control Study

Objectives. Routine measles-mumps-rubella (MMR) vaccine use has greatly decreased the incidence of mumps in the U.S. However, a resurgence of mumps occurred in 2006. We investigated the large outbreak at a university and assessed risk factors for disease. Methods. We described the outbreak and conducted a case-control study. We interviewed case students (identified from student health service and health department records) and control students (selected from a randomly ordered administrative list) and assessed their vaccination status. We compared case students with ≥2 MMR doses and control students with ≥2 MMR doses in univariate and multivariate analyses. Results. The mean age of the 174 case students was 20.9 years; 65% were women. Ninety-seven case students and 147 control students were enrolled in the study. Two-dose MMR coverage was 99% among case and control students with complete records. Only 33% of case students reported exposure to someone with mumps. Case students were more likely than control students to be aged 18 to 19 years (vs. aged 22 years, adjusted odds ratio [AOR] = 5.55; 95% confidence interval [CI] 2.09, 14.74), to report exposure to mumps (AOR=2.31, 95% CI 1.13, 4.73), and to have worked/volunteered on campus (AOR=2.91, 95% CI 1.33, 6.33). Also, women in dormitories had increased odds of mumps compared with men in dormitories. Conclusion. High two-dose MMR coverage was not sufficient to prevent the outbreak. Further study is needed to better understand the effects of dormitory residency and gender on mumps transmission. Clinicians should be vigilant for mumps in young adults presenting with parotitis regardless of immunization history.

scholarly journals Helminth infections of great concern among cattle in Nigeria: Insight to its prevalence, species diversity, patterns of infections and risk factors

2020 ◽  
Vol 13 (2) ◽  
pp. 338-344
Author(s):  
Shola David Ola-Fadunsin ◽  
Isau Aremu Ganiyu ◽  
Musa Rabiu ◽  
Karimat Hussain ◽  
Idiat Modupe Sanda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Species Diversity ◽  
Helminth Species ◽  
Physiological Status ◽  
Cattle Industry ◽  
Fecal Samples ◽  
Diversity Patterns ◽  
Helminth Infections ◽  
Standard Procedures ◽  
Significant Difference

Background and Aim: Helminth infections are one of the greatest causes of productive and reproductive loss in animals and man, and in some cases, it results in heavy mortalities. This study was conducted to determine the prevalence, species diversity, patterns of infections and risk factors associated with helminth infections of cattle in Ilorin, Nigeria. Materials and Methods: A total of 478 fecal samples were collected from abattoirs and cattle farms over a year period (March, 2018-February, 2019). Fecal samples were visually examined then observed using simple flotation and formalin-ethyl acetate sedimentation techniques. Eggs and worms were identified according to standard procedures. The packed cell volume was determined using the hematocrit centrifugation technique. Results: A total of 79.92% of the cattle examined were found positive with one or more helminth species. Eighteen helminth species (cutting across all classes of helminths) were detected, with Haemonchus contortus (60.46%), Trichostrongylus spp. (46.44%), Ostertagia ostertagi (42.05%), Bunostomum phlebotomum (28.87%), Cooperia spp. (24.27%), Oesophagostomum radiatum (21.97%), Strongyloides papillosus (12.13%), and Fasciola gigantica (10.67%) been the most prevalent. Helminth infection was detected all through the year with the least prevalence recorded in February (55.00%). About 61% of the examined cattle harbored double/multiple helminth species. There was a significant difference between breed, sex, physiological status, and season with the prevalence rate of helminth infections (p<0.05). Conclusion: Our investigation demonstrated high prevalence and wide diversity of helminth species, which suggests that helminth infections are of great concern among cattle in Ilorin and Nigeria in general. There is a need for a radical veterinary intervention to curb the menace so as to have an economically robust cattle industry in Nigeria.

scholarly journals RISK FACTORS FOR HUMERAL HEAD OSTEONECROSIS IN PATIENTS WITH PROXIMAL HUMERAL FRACTURES TREATED OPERATIVELY

2021 ◽  
Vol 27 (4) ◽  
pp. 4072-4076
Author(s):  
Konstantin Totev ◽  
◽  
Georgi Dimitrov ◽  
Lyubomira Toteva ◽  
Svilen Todorov ◽  
...  
Keyword(s):  
Risk Factors ◽  
Humeral Head ◽  
Constant Score ◽  
Functional Results ◽  
Proximal Humeral Fractures ◽  
Humeral Fractures ◽  
Frequent Site ◽  
The Mean ◽  
And Gender

Proximal humerus presents the second most frequent site of posttraumatic osteonecrosis. This complication is usually related to poor functional outcomes. The aim of this study is to identify and analyze the risk factors for posttraumatic humeral head osteonecrosis in surgically treated patients. Ninety-one patients with 92 acute proximal humeral fractures were operated on for a period of 39 months. Operative methods include open reduction and internal fixation and closed reduction and percutaneous fixation. Fractures were classified according to Neer, AO and LEGO classifications. The mean age of patients was 60.9 years. From 91 operated patients for follow-up were available 82. The mean follow-up period was 15 months. Patient data was collected prospectively. Functional results are present using age and gender adjusted Constant score. In 41 patients, the result is excellent, in 28-good, in 11-fair and in 3 poor. Bone union was evident in all cases. No deep wound infections, nerve injuries, vascular injuries and implant failure were observed. Osteonecrosis was seen in 5 (6.1%) patients. Patients with posttraumatic osteonecrosis had significant lower Constant results. Analyzing the pre- and intraoperative factors in patients with osteonecrosis, we find that the most significant factors for this complication are increasing fracture severity and а combination of short medial metaphyseal extension and disrupted medial hinge.

scholarly journals Gastrointestinal helminths of intensively managed poultry in Kwara Central, Kwara State, Nigeria: Its diversity, prevalence, intensity, and risk factors

2019 ◽  
Vol 12 (3) ◽  
pp. 389-396 ◽  
Author(s):  
Shola David Ola-Fadunsin ◽  
Patricia Isioma Uwabujo ◽  
Idiat Modupe Sanda ◽  
Isau Aremu Ganiyu ◽  
Karimat Hussain ◽  
...  
Keyword(s):  
Risk Factors ◽  
Well Being ◽  
Helminth Species ◽  
Farm Size ◽  
Physiological Status ◽  
Flock Size ◽  
Housing Type ◽  
Gastrointestinal Helminths ◽  
Helminth Infections ◽  
Farm Type

Aim: Helminth infections inflict negatively on the production and well-being of animals including poultry. This study was carried out to determine the prevalence, species diversity, intensity, and risk factors associated with the gastrointestinal helminths of intensively raised poultry in Kwara Central senatorial district of Kwara State. Materials and Methods: Fecal samples were collected from 502 poultry species from 15 farms. The samples were subjected to floatation and the formalin-ethyl acetate concentration techniques of examination. The intensity of infections was determined using McMaster counting technique. Results: Seven helminth species were detected with Heterakis gallinarum (10.2%) and Ascaridia galli (6.0%) been the most prevalent, while Capillaria species was the least prevalent (0.8%). Physiological status, bird type, production purpose, farm age (years), presence of other animals in the farm, flock size (birds), farm size (acres), housing type, farm type, frequency of anthelmintic use, distance to waste area (meters), level of biosecurity, and frequency of cleaning the pen were the risk factors significantly (p<0.05) associated with the presence of helminth infections. Conclusion: This study shows that helminth infections are endemic in the study area, as 66.7% of the sampled farms were infected with one or more helminth species. Findings from this study provide information that will assist in improving the poultry sector in Kwara State, Nigeria in general, for better production and profitability.

scholarly journals Within-host mechanisms of immune regulation explain the contrasting dynamics of two helminth species in both single and dual infections

2020 ◽  
Vol 16 (11) ◽  
pp. e1008438
Author(s):  
Chiara Vanalli ◽  
Lorenzo Mari ◽  
Lorenzo Righetto ◽  
Renato Casagrandi ◽  
Marino Gatto ◽  
...  
Keyword(s):  
Immune Responses ◽  
Immune Regulation ◽  
General Trend ◽  
Laboratory Data ◽  
Helminth Species ◽  
Multiple Infections ◽  
Host Immune Responses ◽  
Parasitic Helminths ◽  
Helminth Infections ◽  
Dual Infections

Variation in the intensity and duration of infections is often driven by variation in the network and strength of host immune responses. While many of the immune mechanisms and components are known for parasitic helminths, how these relationships change from single to multiple infections and impact helminth dynamics remains largely unclear. Here, we used laboratory data from a rabbit-helminth system and developed a within-host model of infection to investigate different scenarios of immune regulation in rabbits infected with one or two helminth species. Model selection suggests that the immunological pathways activated against Trichostrongylus retortaeformis and Graphidium strigosum are similar. However, differences in the strength of these immune signals lead to the contrasting dynamics of infections, where the first parasite is rapidly cleared and the latter persists with high intensities. In addition to the reactions identified in single infections, rabbits with both helminths also activate new pathways that asymmetrically affect the dynamics of the two species. These new signals alter the intensities but not the general trend of the infections. The type of interactions described can be expected in many other host-helminth systems. Our immune framework is flexible enough to capture different mechanisms and their complexity, and provides essential insights to the understanding of multi-helminth infections.

Detection of Circulating Tissue Factor and Factor VII in a Normal Population

1996 ◽  
Vol 75 (05) ◽  
pp. 772-777 ◽  
Author(s):  
Sybille Albrecht ◽  
Matthias Kotzsch ◽  
Gabriele Siegert ◽  
Thomas Luther ◽  
Heinz Großmann ◽  
...  
Keyword(s):  
Tissue Factor ◽  
Normal Population ◽  
Mean Value ◽  
Factor Vii ◽  
Significant Difference ◽  
Age Dependent ◽  
The Mean ◽  
Highly Correlated ◽  
And Gender

SummaryThe plasma tissue factor (TF) concentration was correlated to factor VII concentration (FVIIag) and factor VII activity (FVIIc) in 498 healthy volunteers ranging in age from 17 to 64 years. Immunoassays using monoclonal antibodies (mAbs) were developed for the determination of TF and FVIIag in plasma. The mAbs and the test systems were characterized. The mean value of the TF concentration was 172 ± 135 pg/ml. TF showed no age- and gender-related differences. For the total population, FVIIc, determined by a clotting test, was 110 ± 15% and the factor VIlag was 0.77 ± 0.19 μg/ml. FVII activity was significantly increased with age, whereas the concentration demonstrated no correlation to age in this population. FVII concentration is highly correlated with the activity as measured by clotting assay using rabbit thromboplastin. The ratio between FVIIc and FVIIag was not age-dependent, but demonstrated a significant difference between men and women. Between TF and FVII we could not detect a correlation.

Investigation of the Association Between Carotid Artery Intima-Media Thickness (IMT) and Cardiac Risk Factors in Patients with Systemic Lupus Erythematosus

2020 ◽  
Vol 16 (2) ◽  
pp. 125-133
Author(s):  
Zahra Rezaieyazdi ◽  
Sima Sedighi ◽  
Masoumeh Salari ◽  
Mohammadreza H. Fard ◽  
Mahmoud R. Azarpazhooh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Lupus Erythematosus ◽  
Serum Insulin ◽  
Venous Blood ◽  
Test Group ◽  
Control Groups ◽  
Significant Difference ◽  
The Mean ◽  
And Control

Background: The relationship between SLE and traditional risk factors for cardiovascular events was evaluated. Methods: The data regarding sixty patients with SLE and 30 healthy controls (age and sex matched) were gathered using SLEDAI forms. Venous blood (10mL) from all the participants was examined for hs-CRP, homocysteine, VCAM1, CBC, anti-DNA antibody, C3, C4, low-density lipoprotein (LDL), cholesterol, FBS and triglyceride. : The IMT of carotid arteries was determined bilaterally by ultrasound. Other measurements included insulin levels via Elisa (Linco/Millipore Corp) and the HOMA-IR index for insulin resistance. Results: The mean age (in years) in the test and control groups was 28.8±10.3 (18-52) and 33.8±9.13 (18-48), respectively. Results: The mean age (in years) in the test and control groups was 28.8±10.3 (18-52) and 33.8±9.13 (18-48), respectively. : The average IMT in the test group was directly related to serum levels of VCAM1 (p<0.001), homocysteine (p<0.001), cholesterol (p<0.009), LDL (p<0.001), TG (p<0.001), and FPG (p=0.004). The association between other risk factors, insulin resistance, carotid IMT and SLEDAI, was nonexistent. Mean insulin and insulin resistance levels in all the participants were 0.43±2.06 µU/mL and 0.09±0.44, respectively. There was no significant difference between the test and control groups regarding serum insulin and insulin resistance levels (p=0.42 and p=0.9, respectively). None of the risk factors, such as hsCRP, VCAM1, or homocysteine, were shown to be related to insulin resistance (p=0.6, p=0.6, p=0.09, respectively). Conclusion:: Our findings did not show an increase in the prevalence of atherosclerosis in patients with SLE. There was no association between IMT and insulin resistance. However, the former was associated with FPG, total cholesterol, LDL, TG, homocystein and VCAM1.

scholarly journals Outpatient Total Hip Arthroplasty: A Meta-Analysis

2021 ◽  
Vol 11 (15) ◽  
pp. 6853
Author(s):  
Filippo Migliorini ◽  
Lucio Cipollaro ◽  
Francesco Cuozzo ◽  
Francesco Oliva ◽  
Andrea Valerio Marino ◽  
...  
Keyword(s):  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Meta Analysis ◽  
Readmission Rates ◽  
Total Hip ◽  
Vein Thrombosis ◽  
Outpatient Group ◽  
Operative Planning ◽  
The Mean ◽  
And Gender

Introduction: Outpatient total hip arthroplasty (THA) is increasingly popular. This meta-analysis investigated the potential advantages of outpatient regimes for THA. Methods: This study followed the PRISMA guidelines. PubMed, Web of Science, Google Scholar, Embase, and Scopus databases were accessed in June 2021. All clinical studies investigating outpatient THA were considered. The outcomes of interest were pain, infection, mortality, revision, dislocation, readmission rates, and deep vein thrombosis (DVT). Results: Data from 102,839 patients were included. A total of 52% (153,168 of 102,839 patients) were women. The mean age of patients was 62.6 ± 4.6 years, the mean BMI was 29.1 ± 1.8 kg/m2. Good comparability was found in age, BMI, and gender (p > 0.1). No difference was found in pain (p = 0.4), infections (p = 0.9), mortality (p = 0.9), rate of revision (p = 0.1), dislocation (p = 0.9), and readmission (p = 0.8). The outpatient group demonstrated a greater rate of DVT (OR 3.57; 95% CI 2.47 to 5.18; p < 0.0001). Conclusions: In selected patients, outpatient THA can be performed safely with optimal outcomes comparable with inpatient THA. Clear and comprehensive pre-operative planning should involve a multi-disciplinary group composed of orthopaedic surgeons, anaesthesia and rehabilitation specialists, and physiotherapists. Each centre performing outpatient THA should implement continuous homecoming welfare activity, to supervise physiotherapy and monitor anticoagulant therapy.

Thomas Aquinas on Sexual Difference: The Metaphysical Biology and Moral Significance of Human Sexuality

Pro Ecclesia ◽  
2021 ◽  
Vol 30 (2) ◽  
pp. 177-215
Author(s):  
Paul Gondreau
Keyword(s):  
Sexual Difference ◽  
Human Sexuality ◽  
Thomas Aquinas ◽  
Moral Significance ◽  
Male And Female ◽  
Biological Design ◽  
Moral Excellence ◽  
Structural Differences ◽  
The Mean ◽  
And Gender

Thomas Aquinas offers for his time a novel take on human sexual difference, in that he grounds human sexuality in what we might term a metaphysical biology and accords it a privileged role in the moral life. Though his biology is drawn from Aristotle, which leads Aquinas to make problematic statements on sexual difference, he nonetheless offers a perspective that remains deeply relevant and significant for today. His method or approach of tethering sexual difference first and foremost to our animal-like biological design remains perennial, particularly at a time when many seek to dismiss biology as irrelevant to sexual identity and gender difference. The latest findings of the emerging field of neurobiology, which have uncovered structural differences between the male and female brains, offer key support to Aquinas’s approach. Even more important, he holds, in an unprecedented move, that sexual design and inclination provide a veritable source of moral excellence. He goes so far as to locate the mean of virtue in our sexual design and appetites.

scholarly journals Attitudes about Testicular Self-Examination among Polish Males

Biology ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 239
Author(s):  
Tomasz Milecki ◽  
Natalia Majchrzak ◽  
Adam Balcerek ◽  
Maciej Rembisz ◽  
Michał Kasperczak ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Practitioner ◽  
Testicular Cancer ◽  
Family Member ◽  
Malignant Tumor ◽  
Epidemiological Data ◽  
Access To Information ◽  
The Mean ◽  
Original Survey ◽  
Self Examination

Introduction: Epidemiological data indicate an increased incidence of testicular cancer (TC), making it the most common malignant tumor in men from aged 15–45. Oncological and urological associations recommend that men with specific TC risk factors should regularly perform a testicular self-exam (TSE). The aim of the study was to discover the attitudes among Polish males regarding TSE and factors (environmental, social, educational) that affect intention to perform TSE. Methods: An original survey containing 21 questions was used to conduct a study among the Polish branch of VW (Volkswagen Poland) employees. Results: A total of 522 fully completed questionnaires were collected. The mean age of the surveyed respondents was 32 years. Information about TC and how to perform TSE was obtained by 34.4% (n = 185) of the men. It was shown that the following factors increase men’s intention to perform TSE: TC in their family member (p < 0.05; HR = 5.9; 95% Cl: 1.5–23.0), GP’s(General Practitioner) recommendations (p < 0.001; HR = 6.8; 95% Cl: 3.2–14.3), concern expressed by their partner (p < 0.001; HR = 3.3; 95% Cl: 2.1–5.3), and social campaigns (p < 0.001; HR = 2.6; 95% Cl: 1.5–4.6). Conclusions: Approximately half of young polish males do not perform TSE. Access to information on TC prevention is limited. Further action is needed to improve men’s awareness of TC and TSE.

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