scholarly journals Short-term effects of exposure to PM2.5, PM10, NO2, CO, SO2, O3 on lung function test indices among students of Tehran city, Iran

Author(s):  
Siavash Kooranifar ◽  
Gholamreza Alizadeh Attar ◽  
Atefeh Talebi ◽  
Maryam Pourashraf ◽  
Razieh Rostami

Introduction: The adverse health effects of air pollution have been observed in many epidemiological studies. The aim of this research was to study the effects of air pollution on pulmonary functions in schoolchildren in Tehran city. Materials and methods: Total number of 167 schoolchildren were selected to participate in this study. Data were analyzed using analysis of variance (ANOVA) and generalized estimating equation (GEE) to determine the relationship of air pollution and lung function tests. Results: The result of this study showed that there are statistically significant differences in value of air pollution between areas. The results present that concentration of O3, PM10, NO2 has a negative association with lung function tests but concentration of CO, PM2.5, and SO2 had no association with decreased lung function tests. Time variable of air pollution was not statistically significant effect on lung function test. Conclusion: In this study, we conclude that air pollution in Tehran city can be decreased lung function test indexes that may be affected by short-time exposure to air pollutant.

Author(s):  
Padmalochini Sudharsan ◽  
R. Gayatri Devi ◽  
A. Jothi Priya

Introduction: Pulmonary function test is a non-invasive test. It is measured by the spirometer and it gives an idea about the lung volume, lung capacities, rates of flow and gas exchange. Breathing exercise can increase lung function. The commonly performed breathing exercises are blowing bubbles, blow out whistle, pinwheels, Hoberman spheres etc. The aim of this study is to estimate lung function among healthy and blow out whistle beginners. Materials and methods: 60 Dental students consisting of 2 groups were involved in this study. Group 1: Control individuals (30). Group 2 individuals: blow out whistle beginners (30). Standardised RMS Helios spirometer was used. Age of 18-22, Healthy individuals and non-smokers were included in this study and smokers, alcoholic individuals, respiratory disorder individuals and post- COVID individuals were excluded from the study. Data was collected and analysed using paired ‘t’ tests. Significance is considered at P<0.05 level. Results: In this study FVC, FEV1, FEV3 were found to be significant and FEV1/FVC, FEF 25-75, PEFR were found to be insignificant. The post test values of FVC and FEV1 are comparatively higher than the pre test values. The pre test values of FEF 25-75 and  FEV3 are comparatively higher than the post test values. Conclusion: When this blow out exercise is performed there was a significant difference between healthy individuals and blow out whistle beginners. Significant increase in lung function is found. This recreational activity increases lung function which can be a preventive for many pulmonary diseases.


2021 ◽  
Vol 11 (10) ◽  
pp. 348-352
Author(s):  
Onigbinde Michael Olaniyan ◽  
Oninla Samuel Olorunyomi

Sickle cell anaemia (SCA) is a common cause of morbidity and mortality in Nigerian children. Sickle cell haemoglobin disorder and carrier state have incidence at birth in Nigeria of about 2% and 25% respectively. The Chronic anaemia and recurrent vaso-occlusion in this disease condition can lead to impairment of function of body organs or systems. The knowledge on how SCA affects the lung and pulmonary tissue function in Nigerian children is inadequate. Aims: To compare lung function tests results of apparently healthy sickle cell anaemia patients recruited from tertiary hospitals in South West Nigeria with those of apparently healthy controls. Method: A comparative cross sectional study of children attending the Sickle Cell anaemia clinics of Wesley Guild Hospital, Obafemi Awolowo University Teaching Hospital Complex and Ladoke Akintola University of Technology Teaching Hospital was done. Ethical approval was obtained from the Ethical review boards of the different hospitals where the studies were conducted. Randomly selected consenting matched apparently well children and children with Sickle cell anaemia had their weights, height and Packed cell volume on the days of their clinics. In addition the Forced Expiratory Volume at one second, Forced Vital capacity and Peak expiratory flow rates were measured and recorded. The data obtained was analyzed using SPSS 12 version. Results: The total of 74 HBSS patients studied comprised of 35(43.7%) boys and 39 (52.7%) girls, giving a male to female ratio of 1: 1.1, while the 73 apparently healthy controls were made up of 39(53.4%) boys and 34(46.6%) girls, giving a male to female ratio of 1.2 : 1.0. The mean weight and BMI of the children with SCA were 24.9 ± 8.0kg and 14.4 ± 1.8m2 compared with 29.4 ± 2.9kg and 15.4 ± 1.8m2 in the apparently healthy controls. Higher values of weight and BMI in healthy controls than in the SCA subjects and statistically significant p< 0.05. The mean values of the FEV1 , FVC, PEFR and FEV percent were 1.54 ±0.51, 1.76 ± 0.45, 271.37 ± 72.20 and 87.5 ± 4.43 respectively in children with SCA as against 1.83 ± 0.61, 2.03 ± 0.65, 296.44±75.0 and 90.2 ± 5.76 respectively in the healthy controls. Higher lung function tests are statistically significant (p < 0.05). Conclusion: Children with Sickle Cell anaemia have significantly lower anthropometric measurement and lung function test values (FEV1, FVC, & PEFR) than controls. The lower lung function test values in the sickle cell anaemia patients may be as a result of the lower anthropometric measurements. Further studies need to be conducted find out why the lung function tests are lower in children with sickle cell anaemia preferably after eliminating cofounders such as anthropometry. Key words: Lung Function Tests, Sickle Cell Anaemia, Children.


Author(s):  
Dr. Vishal Shamrao Patil ◽  
Dr. (Mrs.) Manisha V. Bhalsing

Lung function tests are useful in assessing the functional status of Respiratory system in both in physiological as well as pathological conditions. These are based on the measurement of volume of air breathed in and out in quite breathing & forced breathing. Air in lungs is classified in to two divisions’ lung volumes & lung capacities. Lung Capacities are the combination of two or more lung volumes. The concept of Rakt Dhatu & Vayu is important in case of respiration because Charaka says that pure blood provides the person with strength, luster & happy life because vital breath follows blood. It represents mechanism of oxygenated & deoxygenated blood & its relation with functioning capacity of Lungs. So In this article attempt has been made to review concepts regarding functions of Rakt Dhatu & Vayu to Establish Lung Function Capacity.


Author(s):  
Jung Keun Choi ◽  
Mi A Son ◽  
Hyun Kyung Kim ◽  
Domyung Paek ◽  
Byung Soon Choi

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1422.3-1423
Author(s):  
T. Hoffmann ◽  
P. Oelzner ◽  
F. Marcus ◽  
M. Förster ◽  
J. Böttcher ◽  
...  

Background:Interstitial lung disease (ILD) in inflammatory rheumatic diseases (IRD) is associated with increased mortality. Moreover, the lung is one of the most effected organs on IRD. Consequently, screening methods were required to the detect ILD in IRD.Objectives:The objective of the following study is to evaluate the diagnostic value of lung function test, chest x-ray and HR-CT of the lung in the detection of ILD at the onset of IRD.Methods:The study is designed as a case-control study and includes 126 patients with a newly diagnosed IRD. It was matched by gender, age and the performance of lung function test and chest x-ray. The sensitivity and specificity were verified by crosstabs and receiver operating characteristic (ROC) curve analysis. The study cohort was divided in two groups (ILD group: n = 63 and control group: n = 63). If possible, all patients received a lung function test and optional a chest x-ray. Patients with pathological findings in the screening tests (chest x-ray or reduced diffusing capacity for carbon monoxide (DLCO) < 80 %) maintained a high-resolution computer tomography (HR-CT) of the lung. Additionally, an immunological bronchioalveolar lavage was performed in the ILD group as gold standard for the detection of ILD.Results:The DLCO (< 80 %) revealed a sensitivity of 83.6 % and specificity of 45.8 % for the detection of ILD. Other examined parameter of lung function test showed no sufficient sensitivity as screening test (FVC = Forced Vital Capacity, FEV1 = Forced Expiratory Volume in 1 second, TLC = Total Lung Capacity, TLCO = Transfer factor of the Lung for carbon monoxide). Also, a combination of different parameter did not increase the sensitivity. The sensitivity and specificity of chest x-ray for the verification of ILD was 64.2 % versus 73.6 %. The combination of DLCO (< 80 %) and chest x-ray showed a sensitivity with 95.2 % and specificity with 38.7 %. The highest sensitivity (95.2 %) and specificity (77.4 %) was observed for the combination of DLCO (< 80 %) and HR-CT of the lung.Conclusion:The study highlighted that a reduced DLCO in lung function test is associated with a lung involvement in IRD. DLCO represented a potential screening parameter for lung manifestation in IRD. Especially patients with suspected vasculitis should receive an additional chest x-ray. Based on the high sensitivity of DLCO in combination with chest x-ray or HR-CT for the detection of ILD in IRD, all patients with a reduced DLCO (< 80%) should obtained an imaging of the lung.Disclosure of Interests:None declared


2019 ◽  
Vol 54 (5) ◽  
pp. 610-619 ◽  
Author(s):  
Azza A. Tantawy ◽  
Amira A. Adly ◽  
Fatma S. E. Ebeid ◽  
Eman A. Ismail ◽  
Mahitab M. Hussein ◽  
...  

2007 ◽  
Vol 26 (2) ◽  
pp. S178
Author(s):  
G. Martensson ◽  
G. Riise ◽  
A. Thylen ◽  
F. Nilsson ◽  
B. Bake

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