Lavender for Sleep Disorder Management in Menopausal Women with or without Hypertension: A Systematic and Meta-analysis

Author(s):  
Mehdi Mameneh ◽  
Ali Rokni ◽  
Masumeh Ghazanfarpour ◽  
Masoudeh Babakhanian

Introduction: Regarding the prevalence of sexual problems during menopause and the interest of women in the use of aromatherapy in attenuating the sleep disorders, and due to the lack of comprehensive meta-analysis on the effects of aromatherapy on the sleep disorders, the present study was conducted to determine the effect of lavender on the sleep disorders in postmenopausal women.Material and Methods: The following databases were selected to search systematically the effect of lavender on the quality of sleep in post-menopausal women, including PubMed, Cochrane Library, ISI Web of Science and Scopus, regardless time limit since inception to September 29, 2019. The quality of trials was investigated according to Jadad scale.Results: After combination of the result of four trials, our meta-analysis showed that treatment with lavender was more effective than placebo in respect with improvement of quality of sleep in menopausal women (Standardized Mean Difference=1.098; Confidence Interval 95%: 0.33-1.86; P= 0.005).Conclusion: Considering the effects of lavender essential oil on improving the quality of sleep in postmenopausal and middle-aged women, this medication can be prescribed in the clinics of sleep problems, obstetrics and gynecology.

Author(s):  
Sergio Garbarino ◽  
Ottavia Guglielmi ◽  
Matteo Puntoni ◽  
Nicola Bragazzi ◽  
Nicola Magnavita

Poor sleep is associated with bad health outcomes, worse wellbeing and decreases in performance, productivity and safety at work. Police officers are exposed to several risk factors including extended work schedules, shift work, occupational stress, dangerous and traumatic events and can, as such, develop sleep problems. The aim of the present study was to analyze the sleep quality among police officers. A systematic literature search, in PubMed/MEDLINE, PsycINFO, Scopus, ISI/Web of Science (WoS) and the Cochrane Library was conducted. Original articles, published in English, French, Italian, Spanish and Portuguese, the primary objective of which was the evaluation of the quality of sleep through the Pittsburgh Sleep Quality Index (PSQI) in Police Forces, were selected. From an initial sample of 1,149 studies, 13 articles were included in the meta-analysis (3,722 police officers). The pooled prevalence of bad sleep quality in police officers was 51% [95%CI 42–60%]. The pooled global score of the PSQI was 5.6 [95%CI 5.0–6.3], corresponding to a low average quality. At the meta-regressions, statistically significant associations could be found for work seniority (in terms of years of service) and being on shift. The poor quality of sleep in police officers could have negative consequences for workers’ health and for the safety of third parts. The implementation of health and sleep hygiene promotion programs in police forces is strongly recommended.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Xiaofen Wang ◽  
Sixiang Cheng ◽  
Huilan Xu

Abstract Background The potential link between sleep disorders and suicidal behaviour has been the subject of several reviews. We performed this meta-analysis to estimate the overall association between sleep disorders and suicidal behaviour and to identify a more specific relationship in patients with depression. Methods A systematic search strategy was developed across the electronic databases PubMed, EMBASE and the Cochrane Library from inception to January 1, 2019 for studies that reported a relationship between sleep disorders and suicidal behaviour in depressed patients. The odds ratio (OR) and corresponding 95% confidence interval (CI) were used to measure the outcomes. Heterogeneity was evaluated by Cochran’s Q test and the I2 statistic. The Newcastle-Ottawa Scale (NOS) was adopted to evaluate the methodological quality of each of the included studies, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess the quality of the evidence. We calculated the overall association between sleep disorders and suicidal behaviour and estimated more specific categories, including insomnia, nightmares, hypersomnia, suicidal ideation, suicide attempt, and completed suicide. Results A total of 18 studies were included in this study. Overall, sleep disorders were closely related to suicidal behaviour in patients with depression (OR = 2.45 95% CI: 1.33 4.52). The relatively increased risks of sleep disorders with suicidal ideation, suicide attempt and completed suicide ranged from 1.24 (95% CI: 1.00 1.53) to 2.41 (95% CI: 1.45 4.02). Nightmares were found to be highly correlated with the risk of suicidal behaviour (OR = 4.47 95% CI: 2.00 9.97), followed by insomnia (OR = 2.29 95% CI: 1.69 3.10). The certainty of the evidence was rated as very low for the overall outcome and the major depression subgroup and was rated as low for the depression subgroup. Conclusions This meta-analysis supports the finding that sleep disorders, particularly nightmares and insomnia, increase the risk of suicidal behaviour in depressed patients. Considering that all included studies were observational, the quality of the evidence is rated as very low. More well-designed studies are needed to confirm our findings and to better explain the mechanisms by which sleep disorders aggravate suicidal behaviour in depressed patients.


Author(s):  
Abha Singh ◽  
Abha Daharwal ◽  
Avinashi Kujur

Background: Sleep disturbance is one of frequent sign and symptom encountered in post-menopausal women. It affects the quality of the life and may lead to depression in some women. Objective of present study was to find out the prevalence of sleep disorder in post-menopausal womenMethods: Prospective study done on the post-menopausal women coming to Gynaecology OPD of Dr Bheem Rao Ambedkar Hospital, Raipur. This study was a prospective cross sectional observational study, conducted in the outpatient department of Obstetrics and Gynecology from 1st August 2016 to 31st January 2017. It included 500 women of postmenopausal age. A detail Performa was provided to assess sleep patterns and disorders associated with it. All the data was analysed using chi square testResults: The prevalence of sleep disturbances was 29.58%. Home makers were affected more in comparison to working women, 71,43% women had problems in initiating sleep. About 2/3rd women in the study group developed insomnia within 5 years of menopause, whereas 1/3rd took more than 7years to develop insomnia. Co morbidities were present in 48% women. Our women have mean age of menopause around 45 years.Conclusions: Sleep disorders are common, with prevalence of 29.5% in menopausal women in present study. It significantly causes psychosocial problems in women. There is need for it to be asked for and to be treated promptly.


2019 ◽  
Vol 6 (1) ◽  
pp. 68-73
Author(s):  
Andrye Fernandes

Chemotherapy has an effect on the occurrence of sleep disorders in children who suffer from acute lymphoblastic leukemia. Sleep disorders experienced by children have an impact on optimizing the long-term quality of life of children. This study aims to describe sleep problems that occur in children suffering from acute lymphoblastic leukemia who undergo induction phase chemotherapy. The design of this study was descriptive analytic with repeated measurements of sleep disorders in children aged 7-18 years (n = 62). Data collection was carried out for 7 days, that is, one day before, five days during, and one day after chemotherapy. The results of data analysis found that children have > 15 minutes to fall asleep, children have less than normal amounts of sleep (the number of hours of sleep is normal, school age: 9-11 hours / day, adolescence: 8-10 hours / day) and there was a decrease in the quality of sleep scores. In conclusion, there are sleep disorders that occur in children, namely children have less time to sleep, children need a long time to be able to fall asleep, and children experience a decrease in the quality of sleep. The need for exploration of interventions to facilitate efficient sleep according to the stages of child development.


2020 ◽  
Vol 3 (4) ◽  
pp. 173-194
Author(s):  
Alexandra V. Korolenko

Healthy sleep is not only the most important source of restoring the body's strength, but also a way to overcome traumatic events and stress, as well as a resource for the effective functioning of the human nervous system. Many studies confirm the relationship between the duration and quality of sleep and the health status of the population. At the same time, in modern conditions, socio-demographic characteristics of the population are of great importance in determining sleep. The main sleep disorders are recognized not only as a reduction in its duration, but also as a deterioration in quality (problems with falling asleep, a feeling of unreconstructed strength). The purpose of this article is to study the quantitative and qualitative characteristics of sleep in the population (including in the context of the main socio-demographic groups), the prevalence of factors of its disorders and their impact on subjective health assessments. The information base was data from monitoring of physical health of the Vologda oblast population in 2020 (n = 1500). The study identified risk categories for quantitative and qualitative sleep disorders; confirmed the relationship of stress factors, noise pollution and poor housing conditions with the frequency of sleep disorders; proved the impact of sleep problems on self-assessment of health.


2020 ◽  
Vol 25 ◽  
pp. 2515690X2096732
Author(s):  
Noriko Shinjyo ◽  
Guy Waddell ◽  
Julia Green

Sleep problems are widely prevalent and associated with various comorbidities including anxiety. Valerian ( Valeriana officinalis L.) is a popular herbal medicine used as a sleep aid, however the outcomes of previous clinical studies are inconsistent. This study was conducted to update and re-evaluate the available data in order to understand the reason behind the inconsistent outcomes and to provide a broader view of the use of valerian for associated disorders. PubMed, ScienceDirect, and Cochrane Library were searched to retrieve publications relevant to the effectiveness of valerian as a treatment of sleep problems and associated disorders. A total of 60 studies (n=6,894) were included in this review, and meta-analyses were performed to evaluate the effectiveness to improve subjective sleep quality (10 studies, n=1,065) and to reduce anxiety (8 studies, n=535). Results suggested that inconsistent outcomes were possibly due to the variable quality of herbal extracts and that more reliable effects could be expected from the whole root/rhizome. In addition, therapeutic benefits could be optimized when it was combined with appropriate herbal partners. There were no severe adverse events associated with valerian intake in subjects aged between 7 and 80 years. In conclusion, valerian could be a safe and effective herb to promote sleep and prevent associated disorders. However, due to the presence of multiple active constituents and relatively unstable nature of some of the active constituents, it may be necessary to revise the quality control processes, including standardization methods and shelf life.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Xiangji Li ◽  
Tong Wu ◽  
Mengmeng Xiao ◽  
Shanshan Wu ◽  
Li Min ◽  
...  

Abstract Background Adjuvant therapy is a promising treatment to improve the prognosis of cancer patients, however, the evidence base driving recommendations for adjuvant radiotherapy (ART) or chemotherapy (ACT) in retroperitoneal sarcomas (RPS) primarily hinges on observational data. The aim of this study was to evaluate the effectiveness of adjuvant therapy in the management of RPS patients. Methods We searched PubMed, Web of Science, Embase, ASCO Abstracts, and Cochrane Library for comparative studies (until December 2020) of adjuvant therapy versus surgery alone. Data on the following endpoints were evaluated: overall survival (OS), local recurrence (LR), recurrence-free survival (RFS), and metastasis-free survival (MFS). Data were summarized as hazard ratios (HR) with 95% confidence intervals (CI). Risk of bias of studies was assessed with Begg’s and Egger’s tests. Results A total of 15 trials were eligible, including 9281 adjuvant therapy and 21,583 surgery alone cases (20 studies for OS, six studies for RFS, two studies for LR, and two studies for MFS). Meta-analysis showed that ART was associated with distinct advantages as compared to surgery alone, including a longer OS (HR = 0.80, P < 0.0001), a longer RFS (HR = 0.61, P = 0.0002), and a lower LR (HR = 0.31, P = 0.005). However, this meta-analysis failed to demonstrate a benefit of ACT for RPS patients, including OS (HR = 1.11, P = 0.19), RFS (HR = 1.30, P = 0.09) and MFS (HR = 0.69, P = 0.09). In the sensitivity analysis, ACT was associated with a worse OS (HR = 1.19, P = 0.0002). No evidence of publication bias was observed. Conclusions Overall, the quality of the evidence was moderate for most outcomes. The evidence supports that ART achieved a generally better outcome as compared to surgery alone.


2021 ◽  
Vol 8 (1) ◽  
pp. 6
Author(s):  
Rose Nurhudariani ◽  
Yeni Dwi Ratnasari ◽  
Sonhaji Sonhaji ◽  
Siti Nur Umariyah Febriyanti

Baby massage dan baby gym adalah upaya untuk meningkatkan kualitas tidur pada bayi.  Masalah tidur pada bayi di Indonesia cukup banyak, yaitu sekitar 44,2% bayi mengalami gangguan tidur seperti sering terbangun di malam hari. Namun lebih dari 72% orang tua menganggap gangguan tidur bukan suatu masalah atau hanya masalah kecil, hal tersebut diungkapkan oleh sebuah penelitian pada tahun 2014-2015 yang dilaksanakan di lima kota besar di Indonesia Berdasarkan data awal terdapat 20 bayi yang datang ke posyandu dan ditemukan 17 bayi yang mengalami gangguan tidur. Tujuan penelitian untuk mengetahui efektivitas baby massage dan baby gym terhadap kualitas tidur bayi usia 3-6 bulan di Desa Talang Tegal. Jenis penelitian adalah kuantitatif dengan two group pre and post test  design. Sampel sebanyak 34 bayi yang diberikan perlakuan baby massage dan baby gym dilakukan selama 2 minggu 3x seminggu, untuk baby massage 15 menit sedangkan untuk baby gym 5 menit. Terdapat pengaruh baby massage terhadap kualitas tidur bayi usia 3-6 bulan dengan  p value 0.000. Terdapat pengaruh baby gym terhadap kualitas tidur bayi usia 3-6 bulan dengan  p value 0,001. Tidak terdapat perbedaan efektivitas baby massage dan baby gym terhadap kualitas tidur bayi usia 3 – 6 bulan. Kata kunci : baby gym; baby massage; kualitas tidur bayi  The Effectiveness of Baby Massage And Baby Gym on Sleep Quality of 3-6 Months Baby ABSTRACT  Baby massage and baby gym are efforts to improve the quality of sleep in babies. There are quite a number of sleep problems in infants in Indonesia, which is around 44.2% of infants experiencing sleep disorders such as frequent awakenings at night. However, more than 72% of parents consider sleep disturbances not a problem or just a minor problem, this was revealed by a 2014-2015 study conducted in five major cities in Indonesia. Based on initial data there were 20 babies who came to the Integrated Healthcare Centre and found 17 babies with sleep disorders. The purpose of the study was to determine the effectiveness of baby massage and baby gym on the sleep quality of baby aged 3-6 months in Talang Tegal Village. This type of research was quantitative with two groups pre-post test design. A sample of 34 babies who were given baby massage and baby gym treatment was carried out for 2 weeks 3 time each week, for baby massage 15 minutes while for baby gym 5 minutes. There is an effect of baby massage on the sleep quality of babies aged 3-6 months with a p value of 0.000. There is an effect of baby gym on the sleep quality of babies aged 3-6 months with a p value of 0.001. There is no difference in the effectiveness of baby massage and baby gym on the sleep quality of babies aged 3-6 months. Keywords: baby gym; baby massages; sleep quality of baby


2021 ◽  
pp. 1-7
Author(s):  
Jiajie Zhang ◽  
Yicheng Huang ◽  
Yingsha Chen ◽  
Xiaomin Shen ◽  
Hongying Pan ◽  
...  

<b><i>Introduction:</i></b> The aim of this study is to investigate the association between loss of muscle mass and prognosis of sepsis. <b><i>Methods:</i></b> Six databases, including PubMed, Embase, Cochrane Library, Web of Science, Scopus, and Ovid, were searched by the deadline of August 18, 2020. A meta-analysis was conducted on the collected data by means of a random-effects model. The quality of each included article was assessed according to the Newcastle-Ottawa Scale. <b><i>Results:</i></b> Out of 1,819 references, 6 articles and 1 conference abstract were included. Sepsis patients with a loss of muscle mass or sarcopenia had higher mortality (risk ratio [RR]: 1.94, 95% confidence intervals [CI]: 1.59–2.37; I-squared = 18.7%, <i>p</i> &#x3c; 0.001). The RR of mortality within 30 days (RR: 2.31, 95% CI: 1.78–2.99, <i>p</i> &#x3c; 0.001) was higher than that of mortality over 30 days. Loss of psoas muscle mass, as evaluated by CT, showed the highest RR of sepsis mortality. In addition, based on data on overall survival retrieved from 4 trials, the pooled hazard ratio (HR) for patients with a loss of muscle mass or sarcopenia was 3.04. Subgroup analysis showed that survival time was the main source of heterogeneity for the overall HR. Furthermore, the scanning areas of muscle mass in survival patients were 0.33 cm<sup>2</sup>/m<sup>2</sup> higher than those measured in deceased patients. <b><i>Conclusion:</i></b> A loss of muscle mass, as evaluated by CT scan, was associated with a poor outcome in sepsis.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Qianwen Ma ◽  
Yong Tan ◽  
Genlin Mo

Objective. To compare the treatment efficacy of Kuntai capsule with Climen only in the therapy of premature ovarian failure. Methods. Randomized controlled trials were electronically retrieved from PubMed, Cochrane Library, Web of science, CBM, CNKI, Wanfang, and Weipu database. In addition, some related papers were manually checked. All papers were assessed according to the Cochrane Handbook for Systematic Reviews of Interventions, and the effective data were analyzed by Revman 5.3 Software. Results. 11 randomized control trials involving 1068 patients were included. Results of meta-analysis showed that E2 (estrogen), the total therapeutic effective rate of the group of Kuntai capsule, and hormone were higher than hormone only. The LH (luteinizing hormone), FSH (follicle-stimulating hormone), and Kupperman score of the group of Kuntai capsule and Climen were lower than Climen only. Conclusion. Available evidence shows that Kuntai capsule with Climen is more effective than Climen in the therapy of premature ovarian failure. Nowadays, the quality of the research studies is low. More large-scaled randomized trials will need to be carried out.


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