Medicinal Herbs with Potential Anti-Hypertensive Properties: a Systematic Review of Human and Animal Studies

2019 ◽  
Author(s):  
Maryam Isari ◽  
Nazli Namazi ◽  
Mohammad Hossein Ayati ◽  
Roja Rahimi
Keyword(s):  
Blood Pressure ◽  
Blood Vessels ◽  
Animal Studies ◽  
Scientific Evidence ◽  
Research Work ◽  
Vital Signs ◽  
Grape Seed ◽  
Huge Amount ◽  
Herbal Products ◽  
White Mulberry

Blood pressure is one of the vital signs, and is the pressure of circulating blood on the walls of blood vessels. When the large arteries lose their natural elasticity and strength, and the smaller ones are narrowed, blood pressure rises and the pressure is exerted by blood on the walls of blood vessels. High blood pressure is dangerous and very harmful for the heart and blood vessels, and is a major cause of mortality in all nations. Many patients tend to use herbal products for controlling their blood pressure, as they are concerned of the side effects of the chemical drugs. There are huge amount of research work exploring the safety and efficacy of a single herb, or combined herbal products on lowering blood pressure, among which some have shown certain effects, and some are negative in results. Grape seed, Garlic, Saffron, Green and White Mulberry, Quince, and some other herbs have more scientific evidence in lowering blood pressure. In this study, we systematically reviewed the scientific literature of clinical trials and animal studies, in which the safety and effectiveness of herbs on lowering blood pressure were evaluated.

scholarly journals Wireless Electroencephalography Based Blood Pressure Monitoring

2018 ◽  
Vol 7 (4.38) ◽  
pp. 904
Author(s):  
R. A. Jafri ◽  
N. Shahid ◽  
M. F. Shamim ◽  
M. A. Alam ◽  
M. W. Munir ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Research Work ◽  
Vital Signs ◽  
Cardiac Patients ◽  
Research Framework ◽  
Aged People ◽  
Routine Monitoring ◽  
Home Monitor ◽  
Electroencephalogram Eeg

The number of cardiac patients and aged individuals are at a rise all around the world. Taking care of such individuals is a major challenge these days. In many cases, these patients require special care and regular monitoring of vital signs like blood pressure (BP). Focusing a prevalent idea of wireless brain-computer interface (WBCI), an innovative research work is considered to meet essential routine monitoring of BP for cardiac patients and aged people without any reliance. The research framework involves the use of wireless electroencephalogram (EEG) headset to control wrist BP and arm BP monitors to determine accurate BP readings in the proposed system. An Android application "Smart Home Monitor" is developed that screens the information from the headset. The research framework is tested on ten individuals to examine the precision in BP readings from two different BP monitors. Results specify that both upper arm blood pressure readings i.e. Systolic BP readings (SBP = 119.6 ±5.1 mmHg) and Diastolic BP (DBP = 79.5 ±7.4 mmHg) were found to be better than the wrist BP readings (SBP = 128.2 ±11.7 mmHg and DBP = 83.6 ±10.3 mmHg). This examination assessed that the designed system empowers the framework to be reliable, remote and compact.  

scholarly journals Implementation of MEMS Capacitive Pressure Sensor Design using COMSOL Software

2019 ◽  
Vol 8 (2S8) ◽  
pp. 967-972 ◽  
Keyword(s):  
Blood Pressure ◽  
Blood Vessel ◽  
Blood Vessels ◽  
Real Time ◽  
Pressure Sensor ◽  
Vital Signs ◽  
Capacitive Pressure Sensor ◽  
Sensor Design

This paper is based on the research of emerging implantable medical instrumentations. An implantable Blood Pressure (BP) monitoring Microsystems is very essential to monitor patient’s BP continuously and gives warning when they are extreme and interim levels. The instrument should be accurately measure the both systolic and diastolic values. Based on the readings the BP is categorized in to four (Ideal BP: diastolic=120 and systolic=80, low BP 90 and 60, Pre-hyper values are 140 and 90 and hyper tension values are 190 and 100). BP consists one of the principle vital signs referring to the force entered by circulating blood on the walls of blood vessels. The system consists of instrumented elastic cuff, wrapped around a blood vessel, to sense real time blood pressure. In this paper, a MEMS based capacitor pressure sensor is to be designed with less than the dimensions of 0.4x0.5x0.4mm 3 , and with the approximate capacitance of less than 2pF and 1fF per mmHg.

Living Well to Keep Your Pressure Down

EDIS ◽  
2017 ◽  
Vol 2017 (6) ◽  
Author(s):  
Linda B. Bobroff
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Health Problems ◽  
Fact Sheet ◽  
Living Well ◽  
Heart Work ◽  
Major Revision ◽  
Reduce Risk

High blood pressure, or hypertension, can cause serious health problems. It makes your heart work harder and can damage your blood vessels even if you feel okay. Everyone should have their blood pressure checked regularly. If you have certain risk factors, you are more likely to have high blood pressure. This 6-page fact sheet is a major revision that discusses risk factors and ways to reduce risk.

COMPARISON OF ANTIHYPERTENSIVE EFFECT OF MOXONIDINE VERSUS CLONIDINE IN RENAL FAILURE PATIENTS.

2018 ◽  
Vol 6 (9) ◽  
Author(s):  
DR.MATHEW GEORGE ◽  
DR.LINCY JOSEPH ◽  
MRS.DEEPTHI MATHEW ◽  
ALISHA MARIA SHAJI ◽  
BIJI JOSEPH ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Renal Failure ◽  
Blood Flow ◽  
Blood Vessel ◽  
Blood Vessels ◽  
High Blood Pressure ◽  
Antihypertensive Effect ◽  
The Body ◽  
Ability To Work ◽  
Blood Flows

Blood pressure is the force of blood pushing against blood vessel walls as the heart pumps out blood, and high blood pressure, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body. Factors that can increase this force include higher blood volume due to extra fluid in the blood and blood vessels that are narrow, stiff, or clogged(1). High blood pressure can damage blood vessels in the kidneys, reducing their ability to work properly. When the force of blood flow is high, blood vessels stretch so blood flows more easily. Eventually, this stretching scars and weakens blood vessels throughout the body, including those in the kidneys.

Implementing Internet of Things in a Remote Patient Medical Monitoring System

2018 ◽  
Vol 6 (8) ◽  
pp. 159 ◽  
Author(s):  
Ifeoma V. Ngonadi
Keyword(s):  
Internet Of Things ◽  
Monitoring System ◽  
Medical Records ◽  
Research Work ◽  
Healthcare Delivery ◽  
Vital Signs ◽  
Personal Digital Assistant ◽  
Computer Applications ◽  
Medical Monitoring ◽  
Remote Patient

The Internet of Things (IoT) is a system of interrelated computing devices, mechanical and digital machines, objects, animals or people that are provided with unique identifiers and the ability to transfer data over a network without requiring human-to-human or human-to-computer interaction. Remote patient monitoring enables the monitoring of patients’ vital signs outside the conventional clinical settings which may increase access to care and decrease healthcare delivery costs. This paper focuses on implementing internet of things in a remote patient medical monitoring system. This was achieved by writing two computer applications in java in which one simulates a mobile phone called the Intelligent Personal Digital Assistant (IPDA) which uses a data structure that includes age, smoking habits and alcohol intake to simulate readings for blood pressure, pulse rate and mean arterial pressure continuously every twenty five which it sends to the server. The second java application protects the patients’ medical records as they travel through the networks by employing a symmetric key encryption algorithm which encrypts the patients’ medical records as they are generated and can only be decrypted in the server only by authorized personnel. The result of this research work is the implementation of internet of things in a remote patient medical monitoring system where patients’ vital signs are generated and transferred to the server continuously without human intervention.

IMPLANTATION OF THE INVASIVE BLOOD PRESSURE CATHETER: AN INTEGRATIVE REVIEW OF THE LITERATURE

2018 ◽  
Vol 4 ◽  
Author(s):  
Fabiana Rezer ◽  
Hélio Penna Guimarães ◽  
Grazia Maria Guerra
Keyword(s):  
Blood Pressure ◽  
Patient Care ◽  
Latin American ◽  
Scientific Evidence ◽  
Caribbean Literature ◽  
Health Sciences ◽  
Integrative Review ◽  
Review Of The Literature ◽  
Medical Subject Headings ◽  
Invasive Blood Pressure

Objective: to describe scientific evidence on the implementation and control of the device for measuring invasive blood pressure (IBP). Methods: integrative review of the literature, based on Latin American and Caribbean Literature in Health Sciences (LILACS), Scientific Electronic Library Online (SciELO), PubMed, through the Descriptors in Health Sciences (DeCS) and the Medical Subject Headings (MesH): hemodynamic; monitoring; blood pressure; invasive. Articles were selected in English, Portuguese and Spanish, published between 2009 and 2018. The search resulted in a sample of 10 articles. Results: The articles were analyzed and presented in 4 thematic groups according to the information they provided regarding the puncture of the IBP catheter, being: 1- Indications for IBP catheter puncture; 2 -Contraindications and complications resulting from the use of the IBP catheter; 3 -Most indicated puncture sites; 4- Implementation and maintenance of IBP catheter. Conclusion: Further research may contribute to patient care with an IAP device, as well as assisting physicians and nurses in patient care, reducing the risks and potential adverse events of the IAP.

scholarly journals Potential Benefits of Bovine Colostrum in Pediatric Nutrition and Health

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2551
Author(s):  
Per Torp Sangild ◽  
Caitlin Vonderohe ◽  
Valeria Melendez Hebib ◽  
Douglas G. Burrin
Keyword(s):  
Preterm Birth ◽  
Human Milk ◽  
Animal Studies ◽  
Scientific Evidence ◽  
Growth Failure ◽  
Nutritional Supplement ◽  
Bovine Colostrum ◽  
Infants And Children ◽  
Clinical Complications ◽  
Potential Benefits

Bovine colostrum (BC), the first milk produced from cows after parturition, is increasingly used as a nutritional supplement to promote gut function and health in other species, including humans. The high levels of whey and casein proteins, immunoglobulins (Igs), and other milk bioactives in BC are adapted to meet the needs of newborn calves. However, BC supplementation may improve health outcomes across other species, especially when immune and gut functions are immature in early life. We provide a review of BC composition and its effects in infants and children in health and selected diseases (diarrhea, infection, growth-failure, preterm birth, necrotizing enterocolitis (NEC), short-bowel syndrome, and mucositis). Human trials and animal studies (mainly in piglets) are reviewed to assess the scientific evidence of whether BC is a safe and effective antimicrobial and immunomodulatory nutritional supplement that reduces clinical complications related to preterm birth, infections, and gut disorders. Studies in infants and animals suggest that BC should be supplemented at an optimal age, time, and level to be both safe and effective. Exclusive BC feeding is not recommended for infants because of nutritional imbalances relative to human milk. On the other hand, adverse effects, including allergies and intolerance, appear unlikely when BC is provided as a supplement within normal nutrition guidelines for infants and children. Larger clinical trials in infant populations are needed to provide more evidence of health benefits when patients are supplemented with BC in addition to human milk or formula. Igs and other bioactive factors in BC may work in synergy, making it critical to preserve bioactivity with gentle processing and pasteurization methods. BC has the potential to become a safe and effective nutritional supplement for several pediatric subpopulations.

scholarly journals The Effects of Medicinal Plants and Bioactive Natural Compounds on Homocysteine

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3081
Author(s):  
Mohammad Amin Atazadegan ◽  
Mohammad Bagherniya ◽  
Gholamreza Askari ◽  
Aida Tasbandi ◽  
Amirhossein Sahebkar
Keyword(s):  
Clinical Trials ◽  
Medicinal Plants ◽  
Vascular Endothelium ◽  
Animal Studies ◽  
Natural Compounds ◽  
Herbal Products ◽  
Mortality And Morbidity ◽  
Beneficial Effects ◽  
Serum Homocysteine ◽  
Prevention And Treatment

Background: Among non-communicable diseases, cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity in global communities. By 2030, CVD-related deaths are projected to reach a global rise of 25 million. Obesity, smoking, alcohol, hyperlipidemia, hypertension, and hyperhomocysteinemia are several known risk factors for CVDs. Elevated homocysteine is tightly related to CVDs through multiple mechanisms, including inflammation of the vascular endothelium. The strategies for appropriate management of CVDs are constantly evolving; medicinal plants have received remarkable attention in recent researches, since these natural products have promising effects on the prevention and treatment of various chronic diseases. The effects of nutraceuticals and herbal products on CVD/dyslipidemia have been previously studied. However, to our knowledge, the association between herbal bioactive compounds and homocysteine has not been reviewed in details. Thus, the main objective of this study is to review the efficacy of bioactive natural compounds on homocysteine levels according to clinical trials and animal studies. Results: Based on animal studies, black and green tea, cinnamon, resveratrol, curcumin, garlic extract, ginger, and soy significantly reduced the homocysteine levels. According to the clinical trials, curcumin and resveratrol showed favorable effects on serum homocysteine. In conclusion, this review highlighted the beneficial effects of medicinal plants as natural, inexpensive, and accessible agents on homocysteine levels based on animal studies. Nevertheless, the results of the clinical trials were not uniform, suggesting that more well-designed trials are warranted.

scholarly journals FRI0618-HPR EFFECTS OF MUSIC THERAPY ON PAIN, ANXIETY, AND VITAL SIGNS IN CHRONIC INFLAMMATORY RHEUMATIC DISEASES PATIENTS DURING BIOLOGICAL DRUGS INFUSION

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 914.2-914
Author(s):  
S. Boussaid ◽  
M. Ben Majdouba ◽  
S. Jriri ◽  
M. Abbes ◽  
S. Jammali ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Music Therapy ◽  
Systolic Blood Pressure ◽  
Respiratory Rate ◽  
Vital Signs ◽  
Biological Therapies ◽  
Biological Drugs ◽  
Pain Anxiety ◽  
The Mean

Background:Music therapy is based on ancient cross-cultural beliefs that music can have a “healing” effect on mind and body. Research determined that listening to music can increase comfort and relaxation, relieve pain, lower distress, reduce anxiety, improve positive emotions and mood, and decrease psychological symptoms. Music therapy has been used greatly in various medical procedures to reduce associated anxiety and pain. Patients have a high level of anxiety when they are in the hospital, this is the case of patients with rheumatic diseases who consult regularly to have intravenous infusion of biological therapies.Objectives:The purpose of this study was to examine the effectiveness of music therapy on pain, anxiety, and vital signs among patients with chronic inflammatory rheumatic diseases during intravenous infusion of biological drugs.Methods:Fifty patients were divided into two groups: The experimental group G1 (n=25) received drug infusion while lestening to soft music (30 minutes); and the control group G2 (n=25) received only drug infusion. Measures include pain, anxiety, vital signs (blood pressure, heart rate and respiratory rate). The pain was measured using visual analogic scale (VAS). The state-trait anxiety inventory (STAI) was used for measuring anxiety, low anxiety ranges from 20 to 39, the moderate anxiety ranges from 40 to 59, and high anxiety ranges from 60 to 80. Vital signs (systolic blood pressure [SBP], diastolic blood pressure [DBP], heart rate [HR], and respiratory rate [RR]) were measured before, during and immediately after the infusion.Statistical package for social sciences (SPSS) was used for analysis.Results:The mean age in G1 was 44.45 years (26-72) with a sex ratio (M/F) of 0.8. Including the 25 patients, 12 had rheumatoid arthritis, 10 had ankylosing spondylitis and 3 had psoriatic arthritis. The mean disease duration was 8 years. In G2, the mean age was 46 years (25-70) with a sex ratio (M/F) of 0.75, 12 had rheumatoid arthritis, 11 had ankylosing spondylitis and 2 had psoriatic arthritis. The mean disease duration was 7.5 years. The biological drugs used were: Infliximab in 30 cases, Tocilizumab in 12 cases and Rituximab in 8 cases.Before the infusion, the patients of experimental group had a mean VAS of 5/10±3, a mean STAI of 50.62±6.01, a mean SBP of 13.6 cmHg±1.4, a mean DBP of 8.6 cmHg±1, a mean HR of 85±10 and a mean RR of 18±3. While in control group the mean VAS was 5.5±2, the mean STAI was 50.89±5.5, the mean SBP was 13.4±1.2, the mean DBP was 8.8±1.1, the mean HR was 82±8 and the mean RR was 19±2.During the infusion and after music intervention in G1, the mean STAI became 38.35±5 in G1 versus 46.7±5.2 in G2 (p value=0.022), the mean SBP became 12.1±0.5 in G1 versus 13±1 in G2 (p=0.035), the mean DBP became 8.1±0.8 in G1 versus 8.4±0.9 in G2 (p=0.4), the mean HR became 76±9 in G1 versus 78±7 in G2 (p=0.04) and the mean RR became 17.3±2.1 in G1 versus 18.2±1.7 in G2 (p=0.39).This study found a statistically significant decrease in anxiety, systolic blood pressure and heart rate in patients receiving music interventions during biological therapies infusion, but no significant difference were identified in diastolic blood pressure and respiratory rate.Conclusion:The findings provide further evidence to support the use of music therapy to reduce anxiety, and lower systolic blood pressure and heart rate in patients with rheumatic disease during biological therapies infusion.References:[1] Lin, C., Hwang, S., Jiang, P., & Hsiung, N. (2019).Effect of Music Therapy on Pain After Orthopedic Surgery -A Systematic review and Meta-Analysis. Pain Practice.Disclosure of Interests:None declared

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