scholarly journals Histomorphological Study of Leprosy with Clinical Correlation in Kumaon Region

2019 ◽  
Vol 6 (12) ◽  
pp. 4657-4663
Author(s):  
Neha Yadav ◽  
Binay Kumar ◽  
Usha Joshi ◽  
Mukesh Kumar ◽  
Saurabh Agarwal

Background: Leprosy is a leading cause of permanent physical disability. Approx 60% of global burden of leprosy is represented by India. Histopathological examination is still considered gold standard for accurate categorization of leprosy so that timely treatment can be started. Objectives:  To categorize and correlate types of leprosy clinically and histomorphologically in Kumaon region. Methods: The present cross-sectional study of 62 cases was conducted in the Department of Pathology & Skin and V.D in a tertiary care centre of Kumaon region from August 2016 to April 2018. The cases were clinically examined and categorized according to Ridley-Jopling classification. Skin Biopsy and Slit-Skin Smear (SSS) were taken for accurate histomorphogical categorization of leprosy and assessment of bacterial index, followed by clinico-histomorphological correlation. Statistical analysis was done in term of chi-square test. Kappa test was used as agreement test for clinical versus histological classification of different type of leprosy. Results:  A total of 62 clinically diagnosed leprosy cases evaluated histopathologically. Clinically, lepromatous leprosy (LL) was the most common type of leprosy (38.70%), followed by borderline tuberculoid (30.64%). On histopathological examination, indeterminate leprosy (IL) (21 cases; 33.90%) was the most common followed by lepromatous leprosy (16 cases; 25.80%).  Overall clinico-histopathological correlation was seen in 36 cases (58. 06%) with maximum correlation seen in indeterminate leprosy (100%) and tuberculoid leprosy (TT) (100%). Conclusion: This study concludes that correlation of clinical and histopathological features along with bacterial index is more useful for accurate typing of leprosy than considering any of the single parameter alone so that early and appropriate treatment could be started.

Author(s):  
Harish Gangaraju ◽  
Raghu M. T. ◽  
Yogendra M. ◽  
Virupakshappa H. E. ◽  
Ashwini S. ◽  
...  

<p class="abstract"><strong>Background:</strong> Erythroderma is a cutaneous morphological reaction pattern of skin having many underlying causes and finding the etiology helps in the proper management of erythroderma cases.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study was performed at the department of dermatology, Basaveshwara Medical College, Hospital and Research center, Chitradurga. Authors studied 30 consecutive cases of erythroderma from July 2017 to June 2019 with respect to the epidemiological, clinical and histological data. Clinico-histological correlation was analyzed for etiology of erythroderma.<strong></strong></p><p class="abstract"><strong>Results:</strong> The mean age of onset was 35.03 years with a male to female ratio of 3:2. In addition to erythrema and scaling that were present in all patinets, other co-existent features included were pruritus (43.3%), fever (23.3%), and edema (16.7%). Of the pre-existing dermatoses, psoriasis was the most common (36.6%) disease followed by eczema (26.7%), drug-induced erythroderma (16.7%), colloidan baby (3.3%), pityriasisrubrapilaris (3.3%) and in 13.3% of cases, etiology could not be ascertained. Clinico-histopathological correlation could be established in 73.3% of cases.</p><p class="abstract"><strong>Conclusions:</strong> In all erythroderma cases cutaneous features were identical irrespective of etiology. Detailed history, clinico-histopathological examination and other necessary haematological investigations helps to establish the etiology of erythroderma which helps in further management.</p>


2018 ◽  
Vol 5 (6) ◽  
pp. 2209
Author(s):  
Nalini Aswathaman ◽  
Mohamed Sajjid ◽  
C. N. Kamalarathnam ◽  
A. T. Arasar Seeralar

Background: Effective breastfeeding becomes an art with experience. Correct position and attachment is the first step necessary for exclusive breast feeding. However, studies assessing correct position and attachment for breastfeeding in South India are sparse. Hence our study aimed to assess the percentage of mother infant dyads with correct breastfeeding position and attachment along with factors influencing them in a Tertiary care Hospital.Methods: A descriptive cross-sectional study was conducted among the stable dyads in Institute of Obstetrics and Gynaecology using quasi random sampling. 101 dyads were observed for correct position, attachment and effective suckling using WHO B-R-E-A-S-T feed observation form and were scored. Data was analyzed using SPSS software with chi square test, univariate logistic regression and spearman correlation test.Results: Among the 101 dyads, only 30.7% of them had good or average position, 52.47% had good or average attachment and 62.3% had effective suckling at breast. There was significant correlation between breast problem in mother with incorrect position and poor attachment. NICU stay and breast problems were significantly associated with poor attachment. Effective suckling improved significantly as gestational age matured and in infants who had no NICU stay.Conclusions: Practical demonstration on how to hold infants in correct breastfeeding position and drilling with key points for correct position and attachment as soon as possible after delivery will go a long way for promoting exclusive and effective breastfeeding by learning correct technique. Rechecking after counselling will reinforce this learned art.


2016 ◽  
Vol 49 (02) ◽  
pp. 198-205 ◽  
Author(s):  
Surendra B. Patil ◽  
Amit Paramne ◽  
Shree Harsh

ABSTRACT Context: Wound infection increases the hospital stay and adversely affects the recovery of patients. Culture and sensitivity of wound isolates help in proper diagnosis and management of these patients. Aim: To identify common bacteria causing wound infections and their antibiotic sensitivity pattern. Study Design: A cross-sectional study. Place and Duration of Study: Government Medical College and Hospital, Nagpur from October 2013 to October 2015. Materials and Methods: Pus samples were collected by doctors in ward using Sterile Swab Sticks. Bacterial isolates were identified and cultured, and antibiotic culture sensitivity tests were performed. Statistical Analysis Used: Chi-square test. Results: There were a total of 150 patients with infected wounds. Most common organism isolated was Pseudomonas followed by Klebsiella and Staphylococcus aureus. All of these organisms were resistant to most routine antibiotics. Conclusion: We suggest a multidisciplinary approach to wound management, rational drug use, routine microbiological surveillance of wounds and institution of hospital infection control policy.


Author(s):  
Sailendra K. Thakuria ◽  
Monoj K. Deka ◽  
Shah A. Sheikh

Background: Gestational trophoblastic disease (GTD) covers a wide spectrum of benign and malignant conditions that arise from pregnancies with abnormal trophoblastic tissue development. It is a source of significant morbidity as well as increased risk of mortality from their complications if not identified and treated early enough. Our study aimed at the various clinicopathological features of GTDs along with their prevalence in a tertiary care centre.Methods: It was a retrospective cross-sectional study conducted over a period of 3 years from January 2017 to December 2019. All GTD cases were retrieved from department registries and analysed.Results: Out of 60 diagnosed cases of GTDs, 57 cases (95%) were Hydatiform mole. Invasive mole and choriocarcinoma were 2 cases (3%) and 1 cases (2%) respectively. Age ranged from 18-37 years. The most commonly affected age group was 20-25 years with 33 cases (55%). Most cases were presented in the first trimester presenting with bleeding per vagina. The majority of GTD cases belonged to blood group A and 50,000-<1,00,000 mlU/mL beta HCG level.Conclusions: Histopathological examination is helpful for confirmation of diagnosis.It is very important to follow up of such patients for early diagnosis of malignant trophoblastic tumors.


2013 ◽  
Vol 5 (1) ◽  
pp. 11-13
Author(s):  
Mst Syeeda Showkat ◽  
Lubna Khondker ◽  
Shahryar Nabi ◽  
Bishwajit Bhowmik

Background: Transvaginal sonography is superior to transabdominal sonography in most cases of pelvic pathology. Objective: This study was undertaken to see the clinicalpathological characteristics of endometrial hyperplasia. Methodology: This cross sectional study was carried out from January 2007 to December 2008 for a period of two years. All suspected cases of endometrial hyperplasia were included for this study. Transvaginal sonography (TVS) performed and confirmation was done by histopathological examination. Result: A total number of 40 cases were enrolled for this study. The most common diagnosed endometrial pathology was endometrial hyperplasia which was 42.5% cases. Endometrial polyp was diagnosed in 32.5% cases. Endometrial carcinoma was in 7.5% patients and submucosal fibroid was in 10.0%. Conclusion: Endometrial hyperplasia is the most common disease among the women presented with endometrial pathology. DOI: http://dx.doi.org/10.3329/jssmc.v5i1.16198 J Shaheed Suhrawardy Med Coll, 2013;5(1):11-13


Author(s):  
Susmita Bhattacharya ◽  
Amit Kyal ◽  
Payel Mondal ◽  
Partha Mukhopadhyay ◽  
Mrinalini Chowdhury ◽  
...  

Background: Most of the couples suffering from infertility report it to be the most stressful and depressing period of their life, more so if it is a primary infertility. Studies regarding the prevalence and role of infertility-specific stress especially in eastern part of India is very limited. The objective of the present study was to estimate the prevalence of infertility-specific stress and its role in marital adjustment in women diagnosed with infertility.Methods: It was a cross-sectional study done on 80 married couple diagnosed with infertility (both primary and secondary) over 1 year from July 2016 to June,2017. Dyadic Adjustment Scale (DAS), "semi-structured questionnaire" compiled by the authors and "ICD-10 Classification of Mental and Behavioral Disorders (Clinical Descriptions and Diagnostic Guidelines)" were used for the evaluation. The analysis was done using SPSS (version 16) and Chi-square test.Results: Around 86% infertile women and 21% infertile men were found to suffer from mental stress. Infertility related stress were more in patients with primary infertility than in secondary one. Women mostly (56.5%) coped with stress by self-blaming whereas men (58.2%) by blaming the partner.Conclusions: Mental stress was significantly associated with infertility. In fact, maladjustment in marital relation caused by the stress adversely affected the conjugal life and thus also the fertility. Proper counselling of both partners might be helpful to solve this problem.


2020 ◽  
pp. 1-3
Author(s):  
Anup Latne ◽  
Prabhakar Jirvankar

Hypertension is a major public health problem all over the world. The incidence of hypertension is increasing year after year and the prevalence of hypertension is increasing day by day due to increased life expectancy and aging population and their sedentary lifestyle. Hypertension is known to cause microvascular changes and increased cardiovascular risk from it. Microalbuminuria possibly reflects a state of increased renal endothelial permeability and is an easily measured marker of rather diffuse endothelial dysfunction, low grade inflammation and vascular disease burden2. Microalbuminuria has been determined as an important prognostic indicator and has been reported to be associated with increased cardiovascular risk and progressive renal damage. Reliable data on the prevalence of microalbuminuria in the general population and its association with cardiovascular risk factors is limited. Till now, there is little data available regarding screening and early treatment of hypertensive patients with microalbuminuria, as in the case of microalbuminuric non diabetic subjects. With these perspective this cross sectional study of microalbuminuria in non-diabetic hypertensive patients was undertaken to study prevalence of microalbuminuria in Non Diabetic hypertensive patients. Objectives: To determine the prevalence of microalbuminuria in non-diabetic hypertensive patients and to correlate the presence of microalbuminuria with the patients of different clinical profiles. Materials and Methods: This was observational, cross sectional study of Patients diagnosed with hypertension either admitted in ward or attending OPD of Medical College and Tertiary Care Centre. Urine microalbumin creatinine ratio was used for estimation of microalbuminuria. Conclusion: It was proved that microalbuminuria prevalence was directly proportional to the duration of hypertension, the stage of hypertension. Prevalence of microalbuminria was low in ACE inhibitor and ARB treated hypertensive patients.


2021 ◽  
Vol 11 (3) ◽  
pp. 151-157
Author(s):  
Raima Asif ◽  
Naila Azam ◽  
Fatima Ali Raza ◽  
Mehwish Riaz ◽  
Shaista Zulfiqar ◽  
...  

Background: The objective is to assess the knowledge, attitude and practices regarding first aid towards home related injuries among mothers of children less than 5 years of age at tertiary care hospital of Islamabad. Methods: A questionnaire based cross sectional study was conducted in Fauji Foundation Hospital Islamabad. 400 participants were selected using convenience sampling the mother of children under 5 years of age were included and mother of children with any major co morbidity, congenital abnormalities and who didn’t give consent were excluded from the study. A pretested, structured, self-administered questionnaire was used for data collection after obtaining permission from Institutional Ethical Committee. Statistical analysis was carried using SPSS version 20. Frequencies and percentages were computed, descriptive statistical analysis was done. Chi- Square was applied for association between socio demographic variables and knowledge of mothers regarding first aid. Results: About 44% of the mothers and 63% children fall in age group of 31 and 2-5 years respectively. Half of the mothers (48%) are below intermediate level of education. About 34% of the respondents stated bleeding as most urgent and important injury requiring first aid. Regarding attitudes, 50% of the mothers strongly agree towards necessity of first aid and lack of awareness about dealing with domestic injuries. Sixty-five (65%) of the mothers had given first aid to their child. About 33%, 75%, 44% and 39% of the mothers have faced a child with difficulty in breathing; bleeding, burning and insect/sibling bite respectively. Age of mother (p=0.041), education of mother (p=0.001) and total no of children (p=0.001) were significantly associated with knowledge of first aid. Conclusion: Although home accidents are a common problem, mother’s knowledge regarding home accidents was deficient although majority of the respondents have positive attitude.


2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Badri Rijal ◽  
Krishna Rana ◽  
Srijana KC ◽  
Jamuna Lamsal

Introduction: Orthopedic conditions include a range of condition varying from traumatic injuries, congenital anomalies, chronic back-pain, arthritis, rheumatologic conditions, and other. In Nepal, approximately 2.35 million people are living with musculoskeletal conditions in which 175,000 people are suffering with MSD from non-traumatic causes. The aim of the study is to observe the clinical and demographic pattern of orthopedic problems presenting in the hospital. Methods: A descriptive cross-sectional study was done in All Nepal Hospital Private Limited in the month of November. The data from the medical record section was retrospectively collected. Sample size of 384 was included and convenience sampling technique was used. The descriptive statistical analysis was done. Results: Eight hundred forty four cases were included in the study. Implant removal was the main condition for admission in the hospital 105 (12.44%) followed by Forearm Bone Fracture 84 (9.95%) and Cut Injury 64 (7.58%). Most cases presented during the time 6 PM to 12 AM 312 (36.96%). Conclusions: Most of the orthopedic cases presented in the evening and night time. Implant removal, forearm bone fracture and cut injury form the major bulk of the cases.


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