scholarly journals Carbohydrate and lipid metabolism disorders in children with simple obesity accordingto age and degree of obesity

2014 ◽  
Vol 13 (4) ◽  
pp. 27-36 ◽  
Author(s):  
Monika Skoczeń ◽  
◽  
Kacper Radwański ◽  
Joanna Chrzanowska ◽  
Agnieszka Zubkiewicz-Kucharska ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders ◽  
Simple Obesity

SEX DIFFERENCES OF CARBOHYDRATE AND LIPID METABOLISM IMPAIRMENT IN RATS WITH TYPE 2 DIABETES MELLITUS

2018 ◽  
Vol 64 (2) ◽  
pp. 39-45 ◽  
Author(s):  
Nataliia Gorbenko ◽  
Oleksii Borikov ◽  
Olha Ivanova ◽  
K. V. Taran ◽  
T. S. Litvinova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Body Weight ◽  
Lipid Metabolism ◽  
Female Rats ◽  
Glucose And Lipid Metabolism ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders

A sex difference of carbohydrate and lipid metabolism disorders in rats with type 2 diabetes has been studied. It was established that type 2 diabetes leads to a more pronounced deterioration in carbohydrate toleranceand insulin sensitivity in males compared to female rats, but the sex doesn’t affect basal glycemia and fructosamine levels. It was found that the increase of body weight and visceral fat in rats with type 2 diabetes is moremanifested in females than in males. It has been determined that hypertriglyceridemia is higher in diabeticmales compared to diabetic females, and the level of common lipids in the liver, both intact females and femaleswith type 2 diabetes, is lower than that of the males. The obtained results indicate a more expressive impairment of glucose and lipid metabolism in males compared to females with type 2 diabetes

Prognostic value of carbohydrate and lipid metabolism disorders at a young age

2021 ◽  
Vol 24 (1) ◽  
pp. 60
Author(s):  
D.Yu. Serdyukov ◽  
I.I. Zhirkov ◽  
A.V. Gordienko ◽  
A.S. Fedorova
Keyword(s):  
Lipid Metabolism ◽  
Prognostic Value ◽  
Young Age ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders

scholarly journals Hypoglycemic Effects of Polyphenol Complexes from Bilberry Leaves and Fruits Sorbed on Brown Buckwheat Flour -- Experimental Evaluation and Prospects of Use

2022 ◽  
Author(s):  
Nikita Petrov ◽  
Yulia Sidorova ◽  
Alla Kochetkova ◽  
Vladimir Mazo
Keyword(s):  
Lipid Metabolism ◽  
Carbohydrate Metabolism ◽  
Functional Food ◽  
Food Matrix ◽  
Food Ingredient ◽  
Food Ingredients ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders ◽  
Buckwheat Flour

The effects of plant polyphenols on carbohydrate and/or lipid metabolism disorders have wide experimental and clinical justification; however, their effects are limited due to low bioavailability. Thus, the development of technological approaches enhancing their effectiveness and stability is relevant.The aim of this work was to evaluatein vivothe effects of polyphenols from bilberry leaves and fruits, sorbed on the brown buckwheat flour, on C57Bl/6c mice with carbohydrate and lipid metabolism disorders. We assessed in vivothe effect of a food matrix (FM1: bilberry leaf polyphenols sorbed on brown buckwheat flour) on C57Bl/6c mice with induced carbohydrate and lipid metabolism disorders. The aim of the second experiment was to evaluate the effectiveness of prolonged prophylactic consumption of another food matrix (FM2: billberry fruit polyphenols, sorbed on brown buckwheat flour) by C57Bl/6c micewith induced carbohydrate and lipid metabolism disorders. Technological approaches were developed and pilot batches of the food matrices FM1 and FM2were obtained. According to the in vivo testing, a significant decrease in the glucose levels and normalization of glucose tolerance and insulin sensitivity were found in animals treated with FM1. When assessing the in vivo effects of FM2, the hypoglycemic effect of bilberry fruit polyphenols in the composition of the matrix was established. The results of these studies can be used to justify the testing of the developed matrices in a clinical setting and using them as functional food ingredients for preventative nutrition in cases of carbohydrate metabolism disorders. Keywords: polyphenols, food matrix, functional food ingredient, carbohydrate metabolism, lipid metabolism

Roles of microRNAs in carbohydrate and lipid metabolism disorders and their therapeutic potential

Biochimie ◽  
2021 ◽  
Author(s):  
Sujay Paul ◽  
Luis Alberto Bravo Vázquez ◽  
Samantha Pérez Uribe ◽  
Luis Aarón Manzanero Cárdenas ◽  
María Fernanda Ruíz Aguilar ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Therapeutic Potential ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders

scholarly journals Metabolic syndromes, carbohydrate and lipid metabolism disorders in helminthic infections: review of the literature

2018 ◽  
Vol 17 (4) ◽  
pp. 187-198
Author(s):  
E. A. Golovach ◽  
O. S. Fedorova ◽  
T. V. Saprina ◽  
V. V. Ivanov ◽  
E. A. Perina ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Lipid Metabolism ◽  
Pathological Condition ◽  
Experimental Studies ◽  
Review Of The Literature ◽  
The Metabolic Syndrome ◽  
Carbohydrate And Lipid Metabolism ◽  
Helminth Infections ◽  
Lipid Metabolism Disorders ◽  
Helminthic Infections

Metabolic syndrome is a common pathological condition based on an increase of the mass of visceral fat, insulin resistance with hyperinsulinemia, carbohydrate, lipid and protein disorders. The natural course of the metabolic syndrome can be affected by the presence of intercurrent diseases connected with metabolic disorder, and helminthic infections are among them. This review presents an analysis of the results of current epidemiological and experimental studies of metabolic syndrome and abnormalities of carbohydrate and lipid metabolism associated with helminth infections.

Physiotherapy of cicatricial skin changes in the conditions of metabolic syndrome

2020 ◽  
pp. 15-21
Author(s):  
K. V. Kazantseva ◽  
S. N. Nagornev ◽  
V. K. Frolkov
Keyword(s):  
Insulin Resistance ◽  
Metabolic Syndrome ◽  
Lipid Metabolism ◽  
Therapeutic Potential ◽  
Skin Changes ◽  
Fractional Photothermolysis ◽  
Combined Application ◽  
The Metabolic Syndrome ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders

The article analyzes the effectiveness of combined application of fractional photothermolysis and fermencol ultraphonophoresis against the background of metabolic syndrome in patients with cicatricial skin changes. It is shown that the efficiency of combined physiotherapy is reduced if it is performed against the background of metabolic syndrome. It is proved that the leading pathogenetic factors of the metabolic syndrome that reduce the therapeutic potential of physiotherapy procedures are insulin resistance and lipid metabolism disorders. It is found that the use of fractional photothermolysis and fermencol ultraphonophoresis does not affect significantly the main parameters of the metabolic syndrome in patients with or without metabolic syndrome. It is suggested that to increase the effectiveness of physiotherapy in patients with cicatricial skin changes in the presence of disorders of carbohydrate and lipid metabolism, provoked by the development of insulin resistance, additional use of therapeutic factors used to correct metabolic disorders is necessary.

scholarly journals Carbohydrate and lipid metabolism disorders in women with primary hyperparathyroidism: results of cross-sectional study

2019 ◽  
Vol 22 (1) ◽  
pp. 8-13
Author(s):  
Natalia G. Mokrysheva ◽  
Ekaterina A. Dobreva ◽  
Svetlana S. Mirnaya ◽  
Ivan I. Dedov
Keyword(s):  
Cardiovascular Disease ◽  
Parathyroid Hormone ◽  
Lipid Metabolism ◽  
Primary Hyperparathyroidism ◽  
Immunoreactive Insulin ◽  
Healthy Individuals ◽  
Carbohydrate And Lipid Metabolism ◽  
Lipid Metabolism Disorders ◽  
Ionised Calcium ◽  
The Relationship

Background: Patients with primary hyperparathyroidism (PHPT) have increased mortality risk predominantly attributed to cardiovascular disease. Taking the risk factors for cardiovascular disease into account, such as overweight, atherogenic dyslipidaemia, carbohydrate metabolism disorders and insulin resistance (IR), investigation on the the study of the state of carbohydrate and lipid metabolism in patients with PHPT will help to shed light on the pathogenic mechanisms of the disease and, perhaps, to complement the algorithm for selecting treatment strategies for patients with PHPT. Aims: To study the prevalence of carbohydrate and lipid metabolism disorders among patients with PHPT and to identify the relationship between these two disorders with the indicators of mineral metabolism. Materials and methods: A case-control study of a total of age-matched 256 female patients, 220 patients with PHPT and 36 healthy individuals. The group patients with PHPT were sub-divided into two groups, symptomatic and mild form of PHPT. To verify the form of PHPT, ultrasound examinations of the parathyroid glands and kidneys, two-energy x-ray absorptiometry, biochemical studies (concentration of total and ionised calcium, serum phosphorus and the activity of alkaline phosphatase) and assessment of parathyroid hormone concentration were performed. The relationship between form of PHPT and body weight were evaluated retrospectively according to the survey. Among the 109 participants with PHPT (symptomatic PHPT: 82 patients; mild PHPT: 27 patients) and healthy individuals, the biochemical and hormonal parameters of fat (lipid spectrum of blood) and carbohydrate metabolism (content of immunoreactive insulin, HOMA index, presence of fasting glycemia disorder, glucose tolerance disorders and type 2 diabetes mellitus) were evaluated. Results: The symptomatic PHPT was associated with low body mass index (BMI) while the mild PHPT with high BMI. During an oral glucose tolerance test, the postprandial glycemia in symptomatic PHPT was significantly higher than that in mild PHPT (p = 0.036). The content of immunoreactive insulin in the symptomatic PHPT was not correlated with the concentration of parathyroid hormone, but positively correlated with the concentration of ionised calcium in the blood (r = 0.31; p = 0.006). Patients with PHPT showed a direct positive correlation between BMI and IR index (r = 0.67; p 0.001). It is shown that patients with PHPT have increased LDL content in the blood, and the actual blood lipid concentration is associated with the state of kidney function. Conclusions: The obtained data confirm the relationship between phosphoruscalcium metabolism disorders in PHPT and carbohydrate and lipid metabolism disorders. Prospective, controlled studies are warranted to better elucidate the causal relationships of mineral, carbohydrate and fat metabolism disorders in PHPT.

DYSLIPIDEMIA IN THYROID DISORDERS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Kashish Narula ◽  
Narendra Kumar Dara ◽  
Shyam Lal Meena
Keyword(s):  
Lipid Metabolism ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
Carbohydrate And Lipid Metabolism ◽  
History Of ◽  
Thyroid Profile ◽  
Basal Energy Expenditure

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL

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