scholarly journals DENTAL STATUS OF WORKERS OF MINING AND PROCESSING PLANT ENGAGED IN MINING AND PROCESSING OF COPPER-ZINC ORES

2018 ◽  
Vol 22 (1) ◽  
pp. 64-67
Author(s):  
Aigul A. Trofimchuk ◽  
M. F Kabirova ◽  
O. A Gulyaeva ◽  
L. K Karimova ◽  
G. A Salyakhova
Keyword(s):  
Dental Health ◽  
Control Group ◽  
Processing Plant ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Production Factors ◽  
High Prevalence ◽  
Mucous Membranes ◽  
Processing Plants ◽  
Copper Zinc

With the aim of studying the state of periodontal tissues in workers of mining and processing plants engaged in the extraction and processing of copper-zinc ores carried out a comprehensive dental examination of 395 workers of the production and the control group of 90 people. There was a high prevalence and intensity of diseases of hard tissues of teeth, periodontal tissues and mucous membranes of the oral cavity of the miners engaged in the extraction and processing of copper-zinc ores, which correlates with the degree and duration of contact with harmful production factors. The results of the study can be used to optimize the existing system of protection of dental health of the employees of this and other similar enterprises.

Comparative analysis of polymorphic variants of IL-17A and MMP-1 genes with the risk of developing chronic periodontitis in petrochemical workers

2020 ◽  
Vol 60 (10) ◽  
pp. 687-693
Author(s):  
Iskander I. Zaidullin ◽  
Denis O. Karimov ◽  
Lilija K. Karimova ◽  
Milyausha F. Kabirova ◽  
Rasima R. Galimova ◽  
...  
Keyword(s):  
Ethylene Oxide ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Clinical Manifestations ◽  
Control Group ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Number Of Patients ◽  
Increased Risk ◽  
Harmful Substances

The susceptibility to the development and progression of inflammatory periodontal diseases, which depends on genetic and external factors (smoking, stress, oral hygiene), varies widely. In the development of these diseases, an important role is played not only by the presence of periodontal pathogenic microorganisms, but also by the presence of congenital or acquired immunodeficiency, immunoregulatory defects. The immune system plays a key role in the physiological and pathological processes of periodontal tissues. In this regard, IL17, produced by CD4+ Th cells, which has both Pro-inflammatory and protective activity, is of particular interest in the pathogenesis of periodontitis. The aim of study was to identify the relationship between polymorphic loci of the IL-17A (rs2275913) and MMP-1 (rs1799750) genes and clinical manifestations of chronic periodontitis in petrochemical workers. Dental examination was performed in 92 ethylene oxide production workers with chronic periodontitis and 74 patients with chronic periodontitis who did not come into contact with chemical factors (control group). Genotyping of polymorphisms rs2275913 of the IL17A gene and rs1799750 of the MMP1 gene was performed by allele-specific real-time polymerase chain reaction (PCR). Hygienic assessment of the degree of air pollution of the working area with harmful substances was carried out by gas chromatography according to the guidelines for the determination of harmful substances in the air № 5098-89, № 3119-84. When comparing the results of studies of both groups, there were no statistically significant differences in the frequency distributions of allelic variants and genotypes of the IL-17A and MMP-1 genes. The AA/AG genotypes of the IL-17A gene were associated with an increased risk of severe disease compared to the GG genotype in workers in the main group (OR=6.1; 95% CI 1.33-28.5; p=0.021) and in the control group (OR=7.26; 95% CI 1.34-39.25; p=0.016). Carriers of the A allele in the control group increased the risk of severe chronic periodontitis by 2.4 times compared to carriers of the G allele (OR=2.41; 95% CI 1.19-4.87; p=0.014). During the dental examination of employees of the ethylene oxide plant, the clinical course of periodontal diseases was more severe in comparison with the control group, and the number of patients with severe periodontitis was twice as high. It was found that the AA/AG genotypes of the IL-17A gene and the carrier of the A allele are associated with increased susceptibility to the development of severe chronic periodontitis. The association between the MMP-1 gene polymorphism and the risk of severe forms of chronic periodontitis has not been established. A risk factor for the development of inflammatory periodontal diseases in employees of the petrochemical complex is a complex of harmful production factors.

scholarly journals Mineral bischofite complexes in medical rehabilitation of patients with chronic generalized periodontitis

2021 ◽  
Vol 18 (3) ◽  
pp. 154-160
Author(s):  
Agnessa S. Kaisinova ◽  
Ilya V. Zelenski ◽  
Natalia V. Efimenko ◽  
Elena N. Chalaya
Keyword(s):  
Standard Treatment ◽  
Dental Health ◽  
Clinical Effectiveness ◽  
Main Group ◽  
Medical Rehabilitation ◽  
Treatment Programs ◽  
Control Group ◽  
Basic Drug ◽  
Restorative Treatment ◽  
Periodontal Tissues

The purpose of the research is to improve the efficiency of restorative treatment of patients with chronic generalized periodontitis based on the inclusion in therapeutic schemes of innovative mineral bishophytic complexes ― gel "Bishophytic" and rinser "Polymineral." Materials and methods. The study involved 116 patients at the age of 35 to 73 years old suffering from periodontal pathology (mild and moderate chronic generalized periodontitis). They were distributed by simple randomization into 3 groups: the main group included 43 people who received standard treatment in accordance with Russian clinical recommendations for the treatment of periodontitis, 45 minutes later the patients were prescribed some applications with 10% dental gel "Bishophytic" on the gum, in addition, the patients were recommended to use a rinser "Polymineral" for 6 months; the group of comparison included39 people who received standard treatment and gum applications with 10% "Bishophytic" dental gel; the control group) included 38 people who received only standard treatment. Results. Inclusion of mineral bishophytic complexes in treatment programs of patients with CGP contributes to significant reduction of inflammatory activity of periodontal tissues: 61.3% (p 0.01) had the improvement of hygienic and plaque indices in comparison with initial data; 54.6% (р 0,01) had the improvement after additional use of only gum applications with "Bishophytic" gel; the improvement was 52.2% (р 0.01) after basic drug therapy. Thus, the improvement of enzymatic processes was by 30.0% (p 0.01), 26.9% (p 0.01) and 7.8%; reduction of cytokine activity by 62.8% (p0.01), 61.1% (p 0.01) and 40%; the improvement of dental health by 84.0% (p 0.01), 80.7% (p 0.01) and 74.5% (p 0.01) at рkg-ог 0,05 and рkg-ог0,01. Conclusion. Inclusion of innovative mineral bishophytic complexes (gel "Bishophytic" and rinser "Polymineral") in treatment programs of patients with chronic generalized periodontitis contributes to optimization of therapeutic measures: clinical effectiveness in the main group was 93.0%; after usage of dental gel "Bishophytic" (group of comparison) it was 89.7% and after basic therapy (control group) 81.6%.

scholarly journals On the problem of improving dental care for professional athletes

2017 ◽  
Vol 98 (2) ◽  
pp. 256-260
Author(s):  
Dzh G Gadzhiev
Keyword(s):  
Oral Cavity ◽  
Dental Care ◽  
Periodontal Diseases ◽  
Professional Athletes ◽  
Control Group ◽  
Care Organization ◽  
Orthopaedic Care ◽  
Periodontal Tissues ◽  
High Prevalence ◽  
Mouth Guards

Aim. Assessment of organs and tissues of oral cavity of professional athletes who use protective mouth guards. Methods. Dental examination of 340 professional athletes of Olympic reserve at the age of 18 to 32 years with a duration of sport experience of 9-13 years was performed. We investigated the effect of mouth guards on the condition of the marginal periodontium and microbial contamination. Changes in periodontal tissues were diagnosed by means of traditional methods of inspection, probing of the periodontal grooves, recesses, as well as determining tooth mobility. The control group included 20 athletes not using athletic mouth guards during training. Results. High prevalence of caries (in average, in all examined athletes the rate of carious teeth reaches 32.90%) and fairly high prevalence of severe forms of periodontal diseases in those patients were revealed. Evaluation of the structure of the index of teeth with decay and fillings and removed teeth showed major defects in timely dental care organization for professional boxers: their ratio of filled teeth does not exceed 40.36% in average. A significant number of extracted teeth (more than 23%) indicates that the examined patients require dental orthopaedic care. 30 examined athletes wearing protective mouth guards had the strains of P. gingivalis, A. Actinomycetemcomitans and P. oralis revealed. Conclusion. The study of dental status of professional athletes using protective mouth guards, showed high prevalence of inflammatory periodontal diseases and low level of hygienic state of oral cavity.

scholarly journals DENTAL STATUS OF PREGNANT WOMEN AND WAYS TO IMPROVE THE ORGANIZATION OF THERAPEUTIC AND PREVENTIVE MEASURES

2021 ◽  
Author(s):  
TAMAR SHISHNIASHVILI ◽  
ANA ZUBADALASHVILI ◽  
TAMAR SULADZE ◽  
RUSUDAN KVANCHAKHADZE
Keyword(s):  
Pregnant Women ◽  
Periodontal Diseases ◽  
Dental Health ◽  
Health Indicators ◽  
The Body ◽  
Dental Status ◽  
Second Trimester ◽  
Periodontal Tissues ◽  
High Prevalence ◽  
Dental Diseases

As a result of the continuing changes in the condition of tissues and organs of the dental cavity and the body as a whole, there is a rise in the intensity of tooth decay and periodontal diseases with the onset of pregnancy. The aim of our research was to look into the prevalence and severity of pathology in the hard tissues of teeth and periodontal tissues during pregnancy, as well as to figure out how to better organize therapeutic and prophylactic steps for pregnant women. A comprehensive epidemiological study of 170 pregnant women aged 18 to 40 living in Tbilisi was carried out according to the WHO method. The findings show a high prevalence of dental cavity (from 61 percent to 98.8%) and a high severity of dental caries among pregnant women (from 2.55 1.03 to 14.31 5.44). The intensity of caries indicators increased as the gestational stage lengthened, but the greatest increase was observed in the second trimester of pregnancy. The results indicate a substantial prevalence of periodontal pathology (according to the PMA index) among pregnant women, with the level of pathology increasing with their age and gestational age (from 41.7 percent to 78.8 percent). By the end of the second trimester of pregnancy, the most noticeable improvements in periodontal tissues had been observed. Oral hygiene played a big role in determining the presence and incidence of periodontal disease. Low dental health indicators and worsening dental status during pregnancy point to the need for a more comprehensive diagnosis of all risk factors for major dental diseases, as well as the implementation of all stages of therapeutic and prophylactic interventions during pregnancy, based on the findings of a complete dental examination.

The use of homeopathic drugs in the complex treatment of periodontal diseases in children with rheumatic diseases

2021 ◽  
Vol 1 (12) ◽  
pp. 30-36
Author(s):  
A. A. Skakodub ◽  
Ad. A. Mamеdov ◽  
O. I. Admakin ◽  
A. I. Petukhovа ◽  
A. V. Shevlakova
Keyword(s):  
Rheumatic Diseases ◽  
Periodontal Diseases ◽  
Control Group ◽  
Complex Treatment ◽  
Periodontal Tissues ◽  
Dental Examination ◽  
Inflammatory Processes ◽  
The Relationship ◽  
Rheumatological Diseases ◽  
Homeopathic Drugs

The purpose of our study was to increase the level of treatment of periodontal diseases in children with rheumatic diseases through the use of injections of homeopathic drugs in complex treatment. To do this, they conducted a dental examination of children with rheumatological diseases, determined the degree of damage to periodontal tissues using the indices PMA, GI, CPITN and compared with the control group of children. The relationship between inflammatory processes in in periodontal tissues and rheumatic diseases in children was revealed and the effectiveness of homeopathic drugs in the complex treatment of periodontal tissues was assessed.

scholarly journals DENTAL STATUS WORKERS OF PRODUCTION OF FIBER GLASS

2015 ◽  
Vol 11 (1) ◽  
pp. 26-29 ◽  
Author(s):  
Р. Буляков ◽  
R. Bulyakov ◽  
О. Гуляева ◽  
O. Gulyaeva ◽  
Т. Чемикосова ◽  
...  
Keyword(s):  
Dental Status ◽  
Control Group ◽  
Fiber Glass ◽  
Production Factors ◽  
High Prevalence ◽  
And Control

<p>For an assessment of the stomatologic status of workers of production of fiber glass and identification of interrelation of deviations with time and extent of influence of production factors complex epidemiological examination of the stomatologic status of 69 workers and control group of 25 people is conducted. At workers of production of fiber glass the high prevalence and intensity of caries caused by professional harm, the having direct correlation interrelation from duration and extent of contact with harmful factors is revealed. Results of research can be used for optimization of the existing system of protection of the stomatologic health of workers investigated and other similar enterprises.</p>

scholarly journals The condition of hard dental tissues in workers of the mining industry

2016 ◽  
Vol 12 (1) ◽  
pp. 56-61 ◽  
Author(s):  
А. Трофимчук ◽  
A. Trofimchuk ◽  
О. Гуляева ◽  
O. Gulyaeva ◽  
Л. Каримова ◽  
...  
Keyword(s):  
Dental Health ◽  
Mining Industry ◽  
Occupational Exposures ◽  
The State ◽  
Control Group ◽  
Hard Tissue ◽  
Correlation Relationship ◽  
Dental Tissues ◽  
Copper Zinc ◽  
Hard Dental Tissues

To study the state of hard tissue of teeth in workers of mining and processing enterprises, engaged in mining and processing of copper-zinc ores, conducted a comprehensive dental examination 623 workers and a control group of 255 people, аnalysis of the dependence of the state of hard tissue of teeth on the length and degree of exposure to occupational factors in workers of mining and processing enterprises showed a high prevalence of dental hard tissue disease due to occupational exposures, which has a direct correlation relationship of time and degree of exposure to harmful factors. The results can be used for the organization of dental health care system operating under study and other similar companies.

scholarly journals Стан стоматологічного здоров’я дітей, які хворіють на дисметаболічні нефропатії

2017 ◽  
Author(s):  
V. M. Luchynskyi ◽  
I. L. Luchynska ◽  
V. V. Shcherba
Keyword(s):  
Environmental Conditions ◽  
Dental Health ◽  
Healthy Children ◽  
Periodontal Tissue ◽  
Carious Tooth ◽  
Periodontal Tissues ◽  
High Prevalence ◽  
Survey Results ◽  
Goals And Objectives ◽  
Carious Teeth

The urgency of this work is conditioned with the necessity to study dental health of children with dismetabolic nephropathy influenced by toxic environmental factors. The purpose of the study was to explore the prevalence and intensity of dental caries and periodontal tissue diseases in children suffering from dismetabolic nephropathy and living in different environmental conditions. To clarify the goals and objectives of the study there were examined 356 children aged 6–15 years with dismetabolic nephropathy living in different environmental conditions. Analysis of the survey results showed that in children with dismetabolic nephropathy who live in ecologically unfavorable region there is a high prevalence (91.56±2.15%) and intensity (7.36±0.29 carious teeth) of the caries process, compared to the examined children with dismetabolic nephropathy from the clean region (81.48±3.34% and 6.37±0.25 carious tooth? respectively) and compared to physically healthy children (73.60±3.96% and 4.87±0.22 carious tooth, respectively), and was recorded also a higher incidence of complicated forms of caries (18.69±1.25 17.16±1.21 against and 13.84±1.22%, respectively). The prevalence of the periodontal tissues diseases in children with dismetabolic nephropathy from the ecologically adverse region was 1.6 times higher than in children with dismetabolic diseases of kidneys who live in ecologically clean regions.

ANTICYTOKINE ACTIVITY OF THE PROTOZOA BLASTOCYSTIS SPP

2020 ◽  
pp. 44-48
Author(s):  
Bugero N.V. ◽  
Ilyina N.A. ◽  
Aleksandrova S.M.
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Ulcer Disease ◽  
Cytokine Balance ◽  
High Prevalence ◽  
Blastocystis Spp ◽  
High Level ◽  
Eukaryotic Organisms ◽  
High Degree

In addition to the classical pathogens, which are well understood and well identified, new pathogens with the potential to spread epidemiologically are being identified. Some of these little-known organisms are the simplest Blastocystis spp. blastocystostosis. The clinical significance of Blastocystis spp. and its pathogenicity are still under discussion. This parasite belongs to a group of single-celled eukaryotic organisms living in the colon of the human intestine. Blastocystis spp. is known to be found both in people with reduced immune status and in individuals without any clinical manifestation. It has been established that a sufficiently high degree of invasiveness is observed in persons with gastrointestinal tract diseases, dermatosis, allergic reactions, in patients with carriers of the human immunodeficiency virus, etc. Possessing persistence factors, protozoa blastocysts contribute to the inactivation of host defensive mechanisms, providing a stable anthogonistic effect. In recent years, many works have been devoted to the characteristics of the persistent properties of Blastocystis spr., however, individual properties of blastocysts, in particular, anticytokine activity (ACA), have not yet been studied. In this regard, the work studied the anticytokine activity of microorganisms isolated from healthy subjects and patients with gastrointestinal tract diseases. A high prevalence of the studied characteristic in the subjects was shown. The expression of anticytokine activity in the obtained isolates of blastocysts was the highest in the group of persons with gastric ulcer disease, which decreased in the order of duodenal ulcer, chronic cholecystitis, chronic gastritis, etc. The data obtained in this work on the high level of ACA expression in blastocyst isolates obtained from individuals with gastrointestinal diseases as compared with the control group enables to conclude that their exometabolites may influence the local cytokine balance [1], which supports the inflammatory process.

Erythrocyte and reticulocyte parameters during biological monitoring of lead exposure to the body

2020 ◽  
Vol 60 (11) ◽  
pp. 873-876
Author(s):  
Anastasiya G. Khotuleva ◽  
Mariya S. Kozyreva
Keyword(s):  
Biological Monitoring ◽  
Hematological Parameters ◽  
Lead Level ◽  
Statistical Processing ◽  
Absorption Spectrometry ◽  
The Body ◽  
Control Group ◽  
Processing Plant ◽  
Hematological Disorders ◽  
Globin Synthesis

Introduction. The most susceptible to lead is the hematopoietic system of hematopoietic organs due to lead inhibition of heme and globin synthesis and cytotoxic effect on the membrane of Mature red blood cells. The aim of study was to evaluate the informative value of the study of erythrocyte and reticulocyte parameters determined on modern hematological analyzers in patients working in contact with lead during medical and biological monitoring. Materials and methods. 45 employees of the lead battery processing plant and 30 persons of control group were examined. The level of lead in the blood was determined by atomic absorption spectrometry, δ-ALA in the urine-by the reaction of pyrol formation with acetylacetone in terms of gram of creatinine, the study of hematological parameters was performed on a Sysmex HT-2000i analyzer. Statistical processing of the results was performed using the program STATISTICA 10.0. Results. Significant changes in erythrocytic (RDW) and reticulocytic (RET, IRF, LFR, MFR, HFR, RET-He) parameters, erythropoietin in workers in contact with lead compared to the control group, changes in MCV, MCH, RDW, RET indicators in the group working in dynamics after 2 years were revealed. Associations of hematological parameters with biomarkers of exposure and effect (lead level in blood and ALA in urine) were revealed. Conclusions. Assessment of erythrocyte (MCV, MCH, RDW) and reticulocyte parameters (RET% and their distribution by maturity) in dynamics during periodic medical examinations of workers in contact with lead allows us to detect the development of hematological disorders at early stages.

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