The Impact of Ethnicity, Gender, and Marital Status on Periodontal and Systemic Health of Older Subjects in the Trials to Enhance Elders' Teeth and Oral Health (TEETH)

2004 ◽  
Vol 75 (6) ◽  
pp. 817-823 ◽  
Author(s):  
G. Rutger Persson ◽  
Rigmor E. Persson ◽  
Lars G. Hollender ◽  
H. Asuman Kiyak
Keyword(s):  
Oral Health ◽  
Marital Status ◽  
Older Subjects ◽  
Systemic Health ◽  
The Impact

scholarly journals Probiotics and Periodontal Disease: A Current Update

2010 ◽  
Vol 4 (Spl) ◽  
pp. 35-37
Author(s):  
Vivek Gupta ◽  
Bhavana Gupta
Keyword(s):  
Oral Health ◽  
Periodontal Disease ◽  
Present Article ◽  
Periodontal Health ◽  
Health And Disease ◽  
Systemic Health ◽  
Micro Organisms ◽  
The Impact ◽  
A Current

ABSTRACT Probiotics are live micro-organisms that when administered in adequate amounts confer health benefits upon the host. Although a lot of work has been done regarding the effects of probiotic applications on systemic health particularly gastro-intestinal, the impact of probiotics on oral health is relatively new with lots of research going on; the area of probiotics and periodontal disease is still in its infancy. The present article summarizes the role of probiotics in periodontal health and disease and its effectiveness in periodontal therapy.

scholarly journals Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

2019 ◽  
Author(s):  
Abhishek Nag ◽  
Yuko Kurushima ◽  
Ruth C. E. Bowyer ◽  
Philippa M. Wells ◽  
Stefan Weiss ◽  
...  
Keyword(s):  
Oral Health ◽  
Genome Wide Association Study ◽  
European Ancestry ◽  
Blood Metabolites ◽  
Genetic Loci ◽  
Non Invasive ◽  
Genome Wide ◽  
Specific Locus ◽  
Systemic Health ◽  
The Impact

AbstractSaliva, as a biofluid, is inexpensive and non-invasive to obtain, and provides a vital tool to investigate oral health and its interaction with systemic health conditions. There is growing interest in salivary biomarkers for systemic diseases, notably cardiovascular disease. Whereas hundreds of genetic loci have been shown to be involved in the regulation of blood metabolites leading to unprecedented insights into the pathogenesis of complex human diseases, little is known about the impact of host genetics on salivary metabolites. Here we report the first genome-wide association study exploring 476 salivary metabolites in 1,419 subjects of European ancestry from the TwinsUK cohort (discovery phase). A total of 14 salivary metabolites were significantly associated (p<10−10) with genetic variants that mapped to 11 distinct loci, most of which replicated in the Study of Health in Pomerania (SHIP-2) cohort. Interestingly, while only a limited number of the loci that are known to regulate blood metabolites were also associated with salivary metabolites in our study, we identified several novel saliva-specific locus-metabolite associations, including associations for theAGMAT(with the metabolites 4-guanidinobutanoate and beta-guanidinopropanoate),ATP13A5(with the metabolite creatinine) andDPYS(with the metabolites 3-ureidopropionate and 3-ureidoisobutyrate) loci. Our study suggests that there are biological pathways which are specific to the regulation of the salivary metabolome. In addition, some of our findings may have clinical relevance, such as the utility of the pyrimidine (uracil) degradation metabolites in predicting 5-fluorouracil toxicity and the role of the agmatine pathway metabolites as biomarkers of oral health.

scholarly journals The Impact of Oral Health on Systemic Health: Current Challenges and Future Prospective

2018 ◽  
Vol 2 (3) ◽  
Author(s):  
Bhanupriya Mahant
Keyword(s):  
Infectious Disease ◽  
Primary Care ◽  
Oral Health ◽  
Dental Caries ◽  
Oral Pathology ◽  
Point Of View ◽  
Common Infectious Disease ◽  
Systemic Health ◽  
Oral Conditions ◽  
The Impact

Oral pathology is a broad topic, but this article will focus on the oral conditions that have an established or accepted relationship with systemic health: caries and the periodontal disease-gingivitis and periodontitis. Dental caries is probably the most common infectious disease across humanity. Primary anticipation of disease is the best move toward but often difficult to achieve. From a primary care point of view, it is vital that physicians and dentists augment collaboration and share in sequence that can impact the patient’s health. Optimization of patients’ physical condition is the aim of both the medical and dental professions. Key Words: Oral Health, Systemic Health, Dental.

The Impact of Women’s Oral Health on Systemic Health

2013 ◽  
pp. 1473-1488
Author(s):  
Christine Haskin ◽  
Connie Mobley
Keyword(s):  
Oral Health ◽  
Systemic Health ◽  
The Impact

scholarly journals Genome-wide scan identifies novel genetic loci regulating salivary metabolite levels

2020 ◽  
Vol 29 (5) ◽  
pp. 864-875
Author(s):  
Abhishek Nag ◽  
Yuko Kurushima ◽  
Ruth C E Bowyer ◽  
Philippa M Wells ◽  
Stefan Weiss ◽  
...  
Keyword(s):  
Oral Health ◽  
Genome Wide Association Study ◽  
Blood Metabolites ◽  
Genetic Loci ◽  
Regulatory Pathways ◽  
Non Invasive ◽  
Discovery Phase ◽  
Genome Wide ◽  
Systemic Health ◽  
The Impact

Abstract Saliva, as a biofluid, is inexpensive and non-invasive to obtain, and provides a vital tool to investigate oral health and its interaction with systemic health conditions. There is growing interest in salivary biomarkers for systemic diseases, notably cardiovascular disease. Whereas hundreds of genetic loci have been shown to be involved in the regulation of blood metabolites, leading to significant insights into the pathogenesis of complex human diseases, little is known about the impact of host genetics on salivary metabolites. Here we report the first genome-wide association study exploring 476 salivary metabolites in 1419 subjects from the TwinsUK cohort (discovery phase), followed by replication in the Study of Health in Pomerania (SHIP-2) cohort. A total of 14 distinct locus-metabolite associations were identified in the discovery phase, most of which were replicated in SHIP-2. While only a limited number of the loci that are known to regulate blood metabolites were also associated with salivary metabolites in our study, we identified several novel saliva-specific locus-metabolite associations, including associations for the AGMAT (with the metabolites 4-guanidinobutanoate and beta-guanidinopropanoate), ATP13A5 (with the metabolite creatinine) and DPYS (with the metabolites 3-ureidopropionate and 3-ureidoisobutyrate) loci. Our study suggests that there may be regulatory pathways of particular relevance to the salivary metabolome. In addition, some of our findings may have clinical significance, such as the utility of the pyrimidine (uracil) degradation metabolites in predicting 5-fluorouracil toxicity and the role of the agmatine pathway metabolites as biomarkers of oral health.

The impact of self-reported oral health on the quality of life of teenage students with or without orthodontic treatment from North-East of Romania

2016 ◽  
Author(s):  
GEORGETA ZEGAN ◽  
◽  
CRISTINA GENA DASCĂLU ◽  
RADU EDUARD CERNEI ◽  
RADU BOGDAN MAVRU ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Orthodontic Treatment ◽  
North East ◽  
The Impact

Patients With a History of Oronasal Fistula Repair Exhibit Lower Oral Health Measured With Patient-Centric Outcomes Measures

2020 ◽  
pp. 105566562098133
Author(s):  
Alyssa Fritz ◽  
Diana S. Jodeh ◽  
Fatima Qamar ◽  
James J. Cray ◽  
S. Alex Rottgers
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Cleft Palate ◽  
Fistula Repair ◽  
Old Patients ◽  
Oronasal Fistula ◽  
Patient Reported ◽  
History Of ◽  
The Impact

Introduction: Oronasal fistulae following palatoplasty may affect patients’ quality of life by impacting their ability to eat, speak, and maintain oral hygiene. We aimed to quantify the impact of previous oronasal fistula repair on patients’ quality of life using patient-reported outcome psychometric tools. Methods: A cross-sectional study of 8- to 9-year-old patients with cleft palate and/or lip was completed. Patients who had a cleft team clinic between September 2018 and August 2019 were recruited. Participants were divided into 2 groups (no fistula, prior fistula repair). Differences in the individual CLEFT-Q and Child Oral Health Impact Profile-Short Form 19 (COHIP-SF 19) Oral Health scores between the 2 groups were evaluated using a multivariate analysis controlling for Veau classification and syndromic diagnosis. Results: Sixty patients with a history of cleft palate were included. Forty-two (70%) patients had an associated cleft lip. Thirty-two (53.3%) patients had no history of fistula and 28 (46.7%) patients had undergone a fistula repair. CLEFT-Q Dental, Jaw, and Speech Function were all higher in patients without a history of a fistula repair; however, none of these differences were statistically significant. The COHIP-SF 19 Oral Health score demonstrated a significantly lower score in the fistula group, indicating poorer oral health ( P = .05). Conclusions: One would expect that successful repair of a fistula would result in improved function and patient satisfaction, but the consistent trend toward lower CLEFT-Q scores and significantly increased COHIP-SF 19 Oral Health scores in our study group suggests that residual effects linger and that the morbidity of a fistula may not be completely treated with a secondary correction.

scholarly journals Impact on Quality of Life of Patients Treated by Different File Systems for Root Canal Treatment

2021 ◽  
Author(s):  
L.S. Priyanka ◽  
Lakshmi Nidhi Rao ◽  
Aditya Shetty ◽  
Mithra N. Hegde ◽  
Chitharanjan Shetty
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Postoperative Pain ◽  
Root Canal ◽  
File Systems ◽  
Study Groups ◽  
Significant Difference ◽  
Related Quality ◽  
The Impact

Abstract Introduction The outcomes of oral health conditions and therapy for those conditions are described by the term “oral health-related quality of life.” Oral health-related quality of life is recognized by the World Health Organization as an important part of the Global Oral Health Program. The study aims to compare the impact of three root canal preparation systems on patients’ quality of life and correlate postoperative pain with the impact on the quality of life. Materials and Methods A survey was performed in which 90 patients were randomly assigned to three groups based on the root canal preparation system: (1) ProTaper Gold (Dentsply, Tulsa Dental Specialties, Tulsa, Oklahoma, United States), (2) Neoendo flex (Neoendo, India),and (3) Hyflex EDM/CM (Coltene Whaledent) that included 30 participants in each group. Data collection included the implementation of a demographic data questionnaire, Oral Health Impact Profile 14 (quality of life), and visual analogue scale(pain). The questionnaire was given after root canal treatment in the first 24 hours. The data obtained were statistically analyzed. Results No significant differences were found in the quality of life among study groups. Group 1 demonstrated a highly significant difference in the postoperative pain with p value of 2.67. Conclusion Within the limitations of the present study, Protaper Gold showed a highly significant difference in postoperative pain when compared with other file systems. No significant differences were found in the quality of life among the study groups.

scholarly journals The impact of socio-demographic factors on the survival of cancer patients in Zimbabwe

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Idika E. Okorie ◽  
Ricardo Moyo ◽  
Saralees Nadarajah
Keyword(s):  
Risk Factors ◽  
Survival Analysis ◽  
Marital Status ◽  
Cancer Patients ◽  
Hazard Rate ◽  
Significant Risk ◽  
Demographic Factors ◽  
Female Cancer Patients ◽  
Socio Demographic Factors ◽  
The Impact

AbstractWe provide a survival analysis of cancer patients in Zimbabwe. Our results show that young cancer patients have lower but not significant hazard rate compared to old cancer patients. Male cancer patients have lower but not significant hazard rate compared to female cancer patients. Race and marital status are significant risk factors for cancer patients in Zimbabwe.

scholarly journals Oral Health Related Quality of Life and Prosthetic Status among Institutionalized Elderly from the Bucharest Area: A Pilot Study

2021 ◽  
Vol 18 (12) ◽  
pp. 6663
Author(s):  
Laura Iosif ◽  
Cristina Teodora Preoteasa ◽  
Elena Preoteasa ◽  
Ana Ispas ◽  
Radu Ilinca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Age Groups ◽  
Health Related Quality ◽  
Institutionalized Elderly ◽  
Related Quality ◽  
Health Related ◽  
Prosthetic Status ◽  
The Impact

The aim of the study was to assess the oral health related quality of life (OHRQoL) of elderly in care homes, one of Romania’s most vulnerable social categories, to correlate it to sociodemographic, oral health parameters, and prosthodontic status. Therefore, a cross-sectional study was performed on 58 geriatrics divided into 3 age groups, who were clinically examined and answered the oral health impact profile (OHIP-14) questionnaire. Very high rates of complete edentulism in the oldest-old subgroup (bimaxillary in 64.3%; mandibular in 64.3%; maxillary in 85.7%), and alarming frequencies in the other subgroups (middle-old and youngest-old), statistically significant differences between age groups being determined. The OHIP-14 mean score was 14.5. Although not statistically significant, females had higher OHIP-14 scores, also middle-old with single maxillary arch, single mandibular arch, and bimaxillary complete edentulism, whether they wore dentures or not, but especially those without dental prosthetic treatment in the maxilla. A worse OHRQoL was also observed in wearers of bimaxillary complete dentures, in correlation with periodontal disease-related edentulism, in those with tertiary education degree, and those who came from rural areas. There were no statistically significant correlations of OHRQoL with age, total number of edentulous spaces or edentulous spaces with no prosthetic treatment. In conclusion, despite poor oral health and prosthetic status of the institutionalized elderly around Bucharest, the impact on their wellbeing is comparatively moderate.

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