scholarly journals Factors associated with prehospital delay in acute stroke: systematic review

2017 ◽  
Vol 8 (1) ◽  
pp. 14
Author(s):  
Kaliny Oliveira Peixoto ◽  
Carlos Eduardo Rocha Correa

Purpose: Stroke is a major cause of death and disability worldwide. Although thrombolytic therapy is effective, it is still underutilized mainly due to delays in patient assistance. A systematic literature review was made to identify the main factors associated with prehospital delay. Methods: A MEDLINE-Pubmed database search in February 2016 retrieved 896 articles, of which 6 were selected for analysis. Results: Low educational level was identified as the most important factor of delay. Means of transportation, transfer between hospitals, as well as onset of symptoms at home were also relevant. Conclusion: We conclude that educational policies and facilitated access to hospital care are keys to minimize barriers to early stroke treatment.

Toxins ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 134
Author(s):  
Ana Isabel Galván ◽  
Alicia Rodríguez ◽  
Alberto Martín ◽  
Manuel Joaquín Serradilla ◽  
Ana Martínez-Dorado ◽  
...  

Dried fig is susceptible to infection by Aspergillus flavus, the major producer of the carcinogenic mycotoxins. This fruit may be contaminated by the fungus throughout the entire chain production, especially during natural sun-drying, post-harvest, industrial processing, storage, and fruit retailing. Correct management of such critical stages is necessary to prevent mould growth and mycotoxin accumulation, with temperature being one of the main factors associated with these problems. The effect of different temperatures (5, 16, 25, 30, and 37 °C) related to dried-fig processing on growth, one of the regulatory genes of aflatoxin pathway (aflR) and mycotoxin production by A. flavus, was assessed. Firstly, growth and aflatoxin production of 11 A. flavus strains were checked before selecting two strains (M30 and M144) for in-depth studies. Findings showed that there were enormous differences in aflatoxin amounts and related-gene expression between the two selected strains. Based on the results, mild temperatures, and changes in temperature during drying and storage of dried figs should be avoided. Drying should be conducted at temperatures >30 °C and close to 37 °C, while industry processing, storage, and retailing of dried figs are advisable to perform at refrigeration temperatures (<10 °C) to avoid mycotoxin production.


2021 ◽  
pp. 002203452098296
Author(s):  
H. Fransson ◽  
L. Bjørndal ◽  
F. Frisk ◽  
V.S. Dawson ◽  
K. Landt ◽  
...  

Essentially, root fillings are performed to preserve natural teeth. Over time, however, some root-filled teeth will inevitably be extracted. The aim of this historical prospective cohort study in the adult Swedish population was to identify factors associated with extractions within 5 y of registration of a root filling. The cohort consisted of all those whose root fillings had been reported to the tax-funded Swedish Social Insurance Agency (SSIA) in 2009. Demographic data on the individuals registered with a root filling (sex, age, country of birth, disposable income, educational level, and marital status) were received from Statistics Sweden or the SSIA. Dental care setting, tooth type, and any registration of subsequent restorations within 6 mo were received from the SSIA. Multivariable regression analysis was used, and P < 0.05 was considered statistically significant. In total, 216,764 individuals had been registered with at least 1 root filling. Individuals ( n = 824) without complete data were excluded from the analyses. After 5 y, 9.3% of the root-filled teeth had been registered as extracted. Logistic regression analysis found significant associations for all variables except country of birth, disposable income, and educational level. The highest odds ratios for extractions were associated with the type of restoration: teeth with no registration of any restoration and teeth with a direct restoration combined with a post were 3 times more likely to undergo extraction than teeth restored with an indirect restoration combined with a post and core. Overall, high odds ratios for extractions were associated with any type of composite restoration, including composite fillings and crowns combined with or without any post. In summary, after root filling in the Swedish adult population, several individual- and tooth-specific variables were associated with extraction. The reasons for the extractions remain to be studied further.


Genes ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 43
Author(s):  
Tung-Lin Lee ◽  
Pei-Hsuan Lin ◽  
Pei-Lung Chen ◽  
Jin-Bon Hong ◽  
Chen-Chi Wu

Syndromic hereditary hearing impairment (HHI) is a clinically and etiologically diverse condition that has a profound influence on affected individuals and their families. As cutaneous findings are more apparent than hearing-related symptoms to clinicians and, more importantly, to caregivers of affected infants and young individuals, establishing a correlation map of skin manifestations and their underlying genetic causes is key to early identification and diagnosis of syndromic HHI. In this article, we performed a comprehensive PubMed database search on syndromic HHI with cutaneous abnormalities, and reviewed a total of 260 relevant publications. Our in-depth analyses revealed that the cutaneous manifestations associated with HHI could be classified into three categories: pigment, hyperkeratosis/nail, and connective tissue disorders, with each category involving distinct molecular pathogenesis mechanisms. This outline could help clinicians and researchers build a clear atlas regarding the phenotypic features and pathogenetic mechanisms of syndromic HHI with cutaneous abnormalities, and facilitate clinical and molecular diagnoses of these conditions.


1988 ◽  
Vol 74 (3) ◽  
pp. 181-186
Author(s):  
S. P. L. Travis

AbstractThe surface temperature of eight Royal Marine recruits was monitored in the field during Autumn training on Dartmoor (minimum air temperature 4.5°C). The lowest skin temperature recorded was 6.1°C. One subject experienced a toe temperature below 10° for 5.5 hours and below 15°C for 12.6 hours during a 24 hour recording period. Ambient temperature and inactivity during exposure to cold were the main factors associated with low toe temperatures but individual responses varied widely.


2018 ◽  
Vol 70 (6) ◽  
pp. 918-924 ◽  
Author(s):  
Augustin Latourte ◽  
Thomas Bardin ◽  
Pierre Clerson ◽  
Hang-Korng Ea ◽  
René-Marc Flipo ◽  
...  

Agro-Science ◽  
2021 ◽  
Vol 20 (1) ◽  
pp. 57-64
Author(s):  
S. Saidou ◽  
D.G. Iro ◽  
J.M.K. Ambouta

The objective sought by this study is to highlight the socio-economic determinants that could be helpful in scaling up of best land management practices in high demographics areas. Indeed, a survey was carried out in Dan Saga and Tabofatt two villages’ clusters in order to identify the driver factors which explain the high adoption of best land management practices in these areas. The data were collected from 200 farmers (100 from each cluster), randomly chosen. The survey addressed the likelihood of farmer to use agroforestry practices and or erosion control practices, on the basis of four socioeconomics variables: the educational level of farmer (Instr), the distance between their farm and habitation (Prox), the possession of Harnessed Cultivation Unit (HCU) and the land tenure status (Land). Data were subjected to an analysis by statistical modeling of logistic regression. The results show that agroforestry technology is predominated in Dan Saga cluster (90% of citation for agroforestry practices) compare to Tabofatt cluster where people use mostly erosion control practices (76% of citation for erosion control practices). Among the socioeconomics variables, three main factors significantly influenced the adoption of best land management; the educational level of peasants, the modality of land tenure by purchase and by inheritance and the possession of harness unit. In addition, the main land management technologies perform a high profitability compare to state of inaction. These results could serve as a lever for scaling up of regreening policy in other degraded areas of Sahel’s region.


2021 ◽  
Vol 4 (1) ◽  
pp. 1120-1132
Author(s):  
Márcya Cândida Casimiro de Oliveira ◽  
Kelton Dantas Pereira ◽  
Marcos Alexandre Casimiro de Oliveira ◽  
Marcello Antônio T. Costa Pinto ◽  
João Marcos da Costa Lucena ◽  
...  

2017 ◽  
Vol 41 (S1) ◽  
pp. S654-S654
Author(s):  
G. Jmi ◽  
L. Robbana ◽  
F. Ghali ◽  
M. Zghal ◽  
M. Mezghani ◽  
...  

IntroductionThe Alzheimer's patient assistance relationship is a morally painful experience, most frequently discussed in terms of “burden” in the literature, especially as professionals and institutional intermediaries are underdeveloped in Tunisia.GoalIt is intended to assess the level of burden among caregivers of patients with Alzheimer's disease and to search factors associated with a high level of burden.MethodologyThis is a retrospective descriptive study. Patients were recruited from neurology department of Razi hospital, which were hospitalised between the months of December 2012 and March 2013. The burden was measured using the Zarit inventory.Results and discussionThirty patients were included. The majority female, most caregivers are descendants (60%), then, daughters in law (33%), and finally the spouses (23%). 80% of caregivers lived in the same home as patients. Caregivers were asked about all the items of the grid Zarit. The average burden in our sample is 59.9 + 16 3. We observed that 33% have absent to light burden (score <21), 10% have a light to moderate burden (between 21 and 40), 36, 66% have moderate to severe burden (between 41 and 60) and 50% have a severe burden (>60), according to the classification proposed by Zarit. Sex, kinship and cohabitation with the patient were not associated with a higher burden.ConclusionThe study of factors correlated with high levels of burden aims at finding ways of intervention and support to fight against the isolation of caregivers and the occurrence of anxiodepressive complications.Disclosure of interestThe authors have not supplied their declaration of competing interest.


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