scholarly journals Modeling the Population Health Impact of Introducing a Modified Risk Tobacco Product into the U.S. Market

Author(s):  
Smilja Djurdjevic ◽  
Peter N. Lee ◽  
Rolf Weitkunat ◽  
Zheng Sponsiello-Wang ◽  
Frank Lüdicke ◽  
...  

Philip Morris International (PMI) has developed the Population Health Impact Model (PHIM) to quantify, in the absence of epidemiological data, the effects of marketing a candidate modified risk tobacco product (cMRTP) on the public health of a whole population. Various simulations were performed to understand the harm reduction impact on the U.S. population over a 20-year period under various scenarios. The overall reduction in smoking attributable deaths (SAD) over the 20-year period was estimated as 934,947 if smoking completely went away and between 516,944 and 780,433 if cMRTP use completely replaces smoking. The reduction in SADs was estimated as 172,458 for the World Health Organization (WHO) 2025 Target and between 70,274 and 90,155 for the gradual cMRTP uptake. Combining the scenarios (WHO 2025 Target and cMRTP uptake), the reductions were between 256,453 and 268,796, depending on the cMRTP effective dose. These results show how a cMRTP can reduce overall population harm additionally to existing tobacco control efforts.

Author(s):  
Susan Igras ◽  
Marina Plesons ◽  
Venkatraman Chandra-Mouli

Abstract Over the past 25 years, there has been significant progress in increasing the recognition of, resources for, and action on adolescent health, and adolescent sexual and reproductive health (ASRH) in particular. As with numerous other health areas, however, many of the projects that aim to improve ASRH are implemented without well-thought-out plans for evaluation. As a result, the lessons that projects learn as they encounter and address policy and programmatic challenges are often not extracted and placed in the public arena. In such cases, post-project evaluation (PPE) offers the possibility to generate learnings about what works (and does not work), to complement prospective studies of new or follow-on projects. To fill the gap in the literature and guidance on PPE, the World Health Organization developed The project has ended, but we can still learn from it! Practical guidance for conducting post-project evaluations of adolescent sexual and reproductive health projects. This article provides an overview of the guidance by outlining key methodological and contextual challenges in conducting PPE, as well as illustrative solutions for responding to them.


2014 ◽  
Vol 9 (1) ◽  
pp. 38-43 ◽  
Author(s):  
Frederick M Burkle ◽  
Christopher M Burkle

AbstractLiberia, Sierra Leone, and Guinea lack the public health infrastructure, economic stability, and overall governance to stem the spread of Ebola. Even with robust outside assistance, the epidemiological data have not improved. Vital resource management is haphazard and left to the discretion of individual Ebola treatment units. Only recently has the International Health Regulations (IHR) and World Health Organization (WHO) declared Ebola a Public Health Emergency of International Concern, making this crisis their fifth ongoing level 3 emergency. In particular, the WHO has been severely compromised by post-2003 severe acute respiratory syndrome (SARS) staffing, budget cuts, a weakened IHR treaty, and no unambiguous legal mandate. Population-based triage management under a central authority is indicated to control the transmission and ensure fair and decisive resource allocation across all triage categories. The shared responsibilities critical to global health solutions must be realized and the rightful attention, sustained resources, and properly placed legal authority be assured within the WHO, the IHR, and the vulnerable nations. (Disaster Med Public Health Preparedness. 2014;0:1-6)


2018 ◽  
Vol 7 ◽  
Author(s):  
Christine Peta

In 2016, the World Health Organization, through the Global Cooperation on Assistive Technology Initiative, issued the Priority Assistive Products List which is meant to be a guide to member states of the 50 assistive products needed for a basic health care and/or social welfare system; it is also a model from which nations can develop their national priority assistive products lists. The aim of this opinion paper is to share my views about the Priority Assistive Products List on the grounds that it makes no distinct mention of sexual assistive devices, yet research has indicated that sexuality is an area of great concern for persons with disabilities. In any case, sexuality forms a core part of being human, and it impacts on both the physical and mental well-being of all human beings. I conclude in part that, in its present format, the list perpetuates the myth that persons with disabilities are asexual beings who are innocent of sexual thoughts, feelings and experiences. The list also propagates the stereotype that sexuality is a sacred, private, bedroom matter that should be kept out of the public domain, to the detriment of the health and well-being of persons with disabilities.


2021 ◽  
Author(s):  
Peter chew

Abstract Background: The World Health Organization (WHO) said the situation in India was a "devastating reminder" of what the coronavirus could do. India shifts from mass vaccine exporter to importer, worrying the world. Every country needs to vaccinate its citizens faster, vaccination can reduce viral load. This results in vaccination that can reduce transmission, preventing serious illness and death'. Therefore, Countries with higher levels of vaccination can prevent them from becoming "Second India".Preprint study, Vaccination Education App (1). [Peter Chew, 2021] shows that most people do not take the covid-19 vaccine because they question the safety and effectiveness of the vaccine. Therefore, it is important to create a simple formula for calculate the efficiency of the covid-19 vaccine. The purpose of creating this calculation formula is to allow the public to calculate the efficiency of the covid-19 vaccine by themselves, so that they can understand the effectiveness of the vaccine and decide to take the vaccine. This helps to get a high response to COVID vaccinationMethods: Use the Data publish at The New England JOURNAL of MEDICINE, Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine [Fernando P. Polack et all , 2020]. Calculate of Pfizer BioNTech’s COVID-19 vaccine efficiency by using normal formular and Peter Chew Formular , show that the same result are obtain, which is 95.0599 %. In addition, By using public news information, the public can use the Peter Chew formula to easily calculate Covid-19 vaccine efficacy. This is to ensure public can do the calculation themselves. A calculation of relative risk is also provided to provide more information to persuade the public to take the vaccine.Results: The efficiency of Pfizer BioNTech's COVID-19 vaccine for Malaysian medical worker calculated by using the Peter Chew formula is 95.0599 %. In addition, the calculation of Peter Chew's formula also shows that before the vaccination, about 12 medical staff were infected every day, but after the full vaccination, only about one medical worker was infected every two days. The calculation of relative risk can also make it easier for the public to know that people who are not vaccinated with Pfizer BioNTech's COVID-19 vaccine are 22 times more likely to be infected than people who are fully vaccinated. The above results can convince those who easily question the effectiveness of vaccination.Conclusions: Peter Chew Formular easy to calculate, and the data required for the Peter Chew Formular calculation easy to obtain from public news. This is to ensure that the public can calculate the efficacy of the vaccine by themselves. The information on the calculation can let public compare the average target group get infected every day before and after fully vaccination is also an advantage to let public know the effectiveness of vaccination. One of the advantage of Peter Chew formulator is that we can assume a high target population of vaccination with k = 100, such as the medical worker group When k = 100, the Peter Chew formular calculation becomes very simple. The Proof of Peter Chew Formular must also be shown.


2008 ◽  
Vol 13 (16) ◽  
Author(s):  
Collective WHO

The World Health Organization (WHO) Regional Office for Europe established the European Immunization Week (EIW, http://www.euro.who.int/vaccine) in 2005 for three reasons: 1) to raise public awareness of the benefits of immunisation, 2) to support national immunisation systems, and 3) to provide a framework for mobilising public and political support for governmental efforts to protect the public through universal childhood immunisation.


2018 ◽  
Vol 27 (Suppl 1) ◽  
pp. s82-s86 ◽  
Author(s):  
Wendy B Max ◽  
Hai-Yen Sung ◽  
James Lightwood ◽  
Yingning Wang ◽  
Tingting Yao

ObjectivesWe review the Population Health Impact Model (PHIM) developed by Philip Morris International and used in its application to the US Food and Drug Administration (FDA) to market its heated tobacco product (HTP), IQOS, as a modified-risk tobacco product (MRTP). We assess the model against FDA guidelines for MRTP applications and consider more general criteria for evaluating reduced-risk tobacco products.MethodsIn assessing the PHIM against FDA guidelines, we consider two key components of the model: the assumptions implicit in the model (outcomes included, relative harm of the new product vs cigarettes, tobacco-related diseases considered, whether dual or polyuse of the new product is modelled, and what other tobacco products are included) and data used to estimate and validate model parameters (transition rates between non-smoking, cigarette-only smoking, dual use of cigarettes and MRTP, and MRTP-only use; and starting tobacco use prevalence).ResultsThe PHIM is a dynamic state transition model which models the impact of cigarette and MRTP use on mortality from four tobacco-attributable diseases. The PHIM excludes morbidity, underestimates mortality, excludes tobacco products other than cigarettes, does not include FDA-recommended impacts on non-users and underestimates the impact on other population groups.ConclusionThe PHIM underestimates the health impact of HTP products and cannot be used to justify an MRTP claim. An assessment of the impact of a potential MRTP on population health should include a comprehensive measure of health impacts, consideration of all groups impacted, and documented and justifiable assumptions regarding model parameters.


2021 ◽  
Vol 01 ◽  
Author(s):  
Yung Chin Shih

Background: In 2019, when the World Health Organization (WHO) declared COVID-19 (Coronavirus 2019) a pandemic, many of the public managers faced tough situations in their cities due to the simultaneous loss of lives and jobs. In this regard, this study aims to propose a concise model that considers variables like the number of deaths, lethality of the virus, number of jobs and taxes collected by city halls, among others. Our study considers these issues in providing a relevant response and consistent answer to deliberations on the way forward. Method: Mathematical modeling was used to analyze the interaction between the agents involved and computer simulation was chosen to collect results. Results: - Changing the lockdown level (fixed and variable), the results of number of death per week, total number of unemployed, cost of companies and so on are shown. - The results show that for the input data considered, the 0% lockdown (LD) policy is more effective for the economy and tax collection and also succeeds in repressing the effects on the number of deaths. Because of it, the comparison between with pandemic and without pandemic is provided (in percentage). Conclusion: This study shows that implementing the lockdown did not bring expected benefits, because instead of reducing the number of deaths due to the COVID-19, individuals tend to die more from other causes.


Author(s):  
Martina Barchitta ◽  
Annalisa Quattrocchi ◽  
Andrea Maugeri ◽  
Maria Clara La Rosa ◽  
Claudia La Mastra ◽  
...  

The issue of antimicrobial resistance (AMR) is a focus of the World Health Organization, which proposes educational interventions targeting the public and healthcare professionals. Here, we present the first attempt at a regionwide multicomponent campaign in Sicily (Italy), called “Obiettivo Antibiotico”, which aims to raise the awareness of prudent use of antibiotics in the public and in healthcare professionals. The campaign was designed by an interdisciplinary academic team, and an interactive website was populated with different materials, including key messages, letters, slogans, posters, factsheets, leaflets, and videos. The campaign was launched in November 2018 and, as of 21 December 2018, the website had a total of 1159 unique visitors, of which 190 became champions by pledging to take simple actions to support the fight against AMR. Data from social media showed that the audience was between 18 and 54 years of age, with a high proportion of female participants (64%). Interestingly, the LinkedIn page received more than 1200 followers, and Facebook 685 followers. The number of actions taken (pledges) by the audience was 458, evenly divided between experts (53%) and the general public (47%). Additional efforts are needed to reach more people, thus future efforts should focus on further promotion within the Sicilian region to sustain the engagement with the campaign.


2020 ◽  
Vol 11 (2) ◽  
pp. 52-55
Author(s):  
Husnul Khotimah ◽  
Tijaniyah

Self-medication, known as self-medication, has now been widely used by people to treat their own diseases without a doctor's prescription. This is because the cost of examining and just consulting a doctor is very expensive for the community. According to the World Health Organization (WHO) self-medication is defined as the selection and use of drugs, including herbal and traditional medicine, by individuals to treat themselves from disease or symptoms of disease. As well as the world of digital information is currently mushrooming in various information systems to provide information to the public in real time. Therefore, the author will make a research on how web-based information systems can provide information to the public about self-medication for coughs and colds, which people often suffer from. The Multi Attribute Decision Making (MADM) method is one of the superior methods for calculating the parameters for drug decisions that can be consumed by the public, making it easier for people to choose the type of medicine according to the disease they are suffering


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