Deficits in Voice-Identity Processing: Acquired and Developmental Phonagnosia

The voice contains elementary social communication cues, conveying speech, as well as paralinguistic information pertaining to the emotional state and the identity of the speaker. In contrast to vocal-speech and vocal-emotion processing, voice-identity processing has been less explored. This seems surprising, given the day-to-day significance of person recognition by voice. A valuable approach to unravel how voice-identity processing is accomplished is to investigate people who have a selective deficit in recognising voices. Such a deficit has been termed phonagnosia. In the present chapter, we provide a systematic overview of studies on phonagnosia and how they relate to current neurocognitive models of person recognition. We review studies that have characterised people who suffer from phonagnosia following brain damage (i.e. acquired phonagnosia) and also studies, which have examined phonagnosia cases without apparent brain lesion (i.e. developmental phonagnosia). Based on the reviewed literature, we emphasise the need for a careful behavioural characterisation of phonagnosia cases by taking into consideration the multistage nature of voice-identity processing and the resulting behavioural phonagnosia subtypes.

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Deficits in Voice-Identity Processing: Acquired and Developmental Phonagnosia

10.20944/preprints201806.0280.v2 ◽

2018 ◽

Cited By ~ 1

Author(s):

Claudia Roswandowitz ◽

Corrina Maguinness ◽

Katharina von Kriegstein

Keyword(s):

Brain Damage ◽

Social Communication ◽

Emotional State ◽

Brain Lesion ◽

Person Recognition ◽

Paralinguistic Information ◽

The Voice ◽

Vocal Speech ◽

Identity Processing ◽

Vocal Emotion

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Deficits in Voice-Identity ProcessingAcquired and Developmental Phonagnosia

The Oxford Handbook of Voice Perception ◽

10.1093/oxfordhb/9780198743187.013.39 ◽

2018 ◽

pp. 854-892

Author(s):

Claudia Roswandowitz ◽

Corrina Maguinness ◽

Katharina von Kriegstein

Keyword(s):

Social Communication ◽

Emotional State ◽

Brain Lesion ◽

Person Recognition ◽

Paralinguistic Information ◽

The Voice ◽

Vocal Speech ◽

Identity Processing ◽

Vocal Emotion

The voice contains elementary social communication cues, conveying speech, as well as paralinguistic information pertaining to the emotional state and the identity of the speaker. In contrast to vocal-speech and vocal-emotion processing, voice-identity processing has been less explored. This seems surprising, given the day-to-day significance of person recognition by voice. A valuable approach to unravel how voice-identity processing is accomplished is to investigate people who have a selective deficit in recognizing voices. Such a deficit has been termed phonagnosia. This chapter provides a systematic overview of studies on phonagnosia and how they relate to current neurocognitive models of person recognition. It reviews studies that have characterized people who suffer from phonagnosia following brain damage (i.e. acquired phonagnosia) and also studies which have examined phonagnosia cases without apparent brain lesion (i.e. developmental phonagnosia). Based on the reviewed literature, the chapter emphasizes the need for a careful behavioural characterization of phonagnosia cases by taking into consideration the multistage nature of voice-identity processing and the resulting behavioural phonagnosia subtypes.

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Zebra finches are sensitive to prosodic features of human speech

Proceedings of The Royal Society B Biological Sciences ◽

10.1098/rspb.2014.0480 ◽

2014 ◽

Vol 281 (1787) ◽

pp. 20140480 ◽

Cited By ~ 24

Author(s):

Michelle J. Spierings ◽

Carel ten Cate

Keyword(s):

Speech Perception ◽

Emotional State ◽

The Other ◽

Zebra Finches ◽

Prosodic Features ◽

Human Speech ◽

Prosodic Cues ◽

Paralinguistic Information ◽

Final Syllable ◽

Human Specific

Variation in pitch, amplitude and rhythm adds crucial paralinguistic information to human speech. Such prosodic cues can reveal information about the meaning or emphasis of a sentence or the emotional state of the speaker. To examine the hypothesis that sensitivity to prosodic cues is language independent and not human specific, we tested prosody perception in a controlled experiment with zebra finches. Using a go/no-go procedure, subjects were trained to discriminate between speech syllables arranged in XYXY patterns with prosodic stress on the first syllable and XXYY patterns with prosodic stress on the final syllable. To systematically determine the salience of the various prosodic cues (pitch, duration and amplitude) to the zebra finches, they were subjected to five tests with different combinations of these cues. The zebra finches generalized the prosodic pattern to sequences that consisted of new syllables and used prosodic features over structural ones to discriminate between stimuli. This strong sensitivity to the prosodic pattern was maintained when only a single prosodic cue was available. The change in pitch was treated as more salient than changes in the other prosodic features. These results show that zebra finches are sensitive to the same prosodic cues known to affect human speech perception.

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Unraveling the Biopsychosocial Factors of Fatigue and Sleep Problems After Traumatic Brain Injury: Protocol for a Multicenter Longitudinal Cohort Study (Preprint)

10.2196/preprints.11295 ◽

2018 ◽

Author(s):

Jessica Bruijel ◽

Sven Z Stapert ◽

Annemiek Vermeeren ◽

Jennie L Ponsford ◽

Caroline M van Heugten

Keyword(s):

Social Support ◽

Traumatic Brain Injury ◽

Cohort Study ◽

Brain Injury ◽

Brain Damage ◽

Emotional State ◽

Sleep Problems ◽

Family Participation ◽

Severe Tbi ◽

Support Family

BACKGROUND Fatigue and sleep problems are common after a traumatic brain injury (TBI) and are experienced as highly distressing symptoms, playing a significant role in the recovery trajectory, and they can drastically impact the quality of life and societal participation of the patient and their family and friends. However, the etiology and development of these symptoms are still uncertain. OBJECTIVE The aim of this study is to examine the development of fatigue and sleep problems following moderate to severe TBI and to explore the changes in underlying biological (pain, brain damage), psychological (emotional state), and social (support family, participation) factors across time. METHODS This study is a longitudinal multicenter observational cohort study with 4 measurement points (3, 6, 12, and 18 months postinjury) including subjective questionnaires and cognitive tasks, preceded by 7 nights of actigraphy combined with a sleep diary. Recruitment of 137 moderate to severe TBI patients presenting at emergency and neurology departments or rehabilitation centers across the Netherlands is anticipated. The evolution of fatigue and sleep problems following TBI and their association with possible underlying biological (pain, brain damage), psychological (emotional state), and social (support family, participation) factors will be examined. RESULTS Recruitment of participants for this longitudinal cohort study started in October 2017, and the enrollment of participants is ongoing. The first results are expected at the end of 2020. CONCLUSIONS To the authors’ knowledge, this is the first study that examines the development of both post-TBI fatigue and sleep longitudinally within a biopsychosocial model in moderate to severe TBI using both subjective and objective measures. Identification of modifiable factors such as mood and psychosocial stressors may give direction to the development of interventions for fatigue and sleep problems post-TBI. CLINICALTRIAL Netherlands Trial Register NTR7162; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=7162 (Archived by WebCite at http://www.webcitation.org/6z3mvNLuy) INTERNATIONAL REGISTERED REPOR RR1-10.2196/11295

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Controversial Final Years

Franz Joseph Gall ◽

10.1093/oso/9780190464622.003.0019 ◽

2019 ◽

pp. 451-478

Author(s):

Stanley Finger

Keyword(s):

Brain Damage ◽

Strong Evidence ◽

Cerebral Hemorrhage ◽

Anterior Part ◽

Brain Lesion ◽

Georges Cuvier ◽

Cortical Localization ◽

The Brain

Gall remained a controversial figure throughout his life, which ended in Paris in 1828. In his later years, he continued to fight with Georges Cuvier, who had overseen the rejection of his and Spurzheim’s Mémoire to the Institut National in 1808, and with Cuvier’s protégé, physiologist Pierre Flourens. Flourens initially looked favorably on Gall’s doctrine, but during the 1820s his brain lesion experiments on birds and other animals were heralded by the French élite as strong evidence against cortical localization of function. Despite this formidable opposition, Gall did find a supporter of localization of function in physician Jean-Baptiste Bouillaud, who started reporting in 1825 that lesions of the anterior part of the brain are more likely to affect speech than posterior brain damage. Gall’s health began to fail a year later, when he was 68 and began to have strokes. After he succumbed to a cerebral hemorrhage in 1828, his body was buried in Paris’ Cimetiére du Pére-Lachaise, but not his skull, which was examined by his followers and added to his collection. Gall’s organologie, now regarded as phrénologie, now began an even steeper decline in France and throughout the Continent, although “popular phrenology,” with less emphasis on the underlying science, continued to be influential on British and American landscapes.

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Matrix Metalloproteinase-9 Levels are Associated with Brain Lesion and Persistent Venous Occlusion in Patients with Cerebral Venous Thrombosis

Thrombosis and Haemostasis ◽

10.1055/s-0041-1726094 ◽

2021 ◽

Author(s):

Diana Aguiar de Sousa ◽

Maria Conceição Pereira-Santos ◽

Ana Serra-Caetano ◽

Lia Lucas Neto ◽

Ana Luísa Sousa ◽

...

Keyword(s):

Matrix Metalloproteinase ◽

Venous Thrombosis ◽

Brain Damage ◽

Cerebral Venous Thrombosis ◽

Brain Lesion ◽

Venous Occlusion ◽

Matrix Metalloproteinase 9 ◽

Enzyme Linked Immunosorbent Assay ◽

Venous Recanalization ◽

Metalloproteinase 9

Abstract Background Elucidating mechanisms of brain damage in cerebral venous thrombosis (CVT) would be instrumental to develop targeted therapies and improve prognosis prediction. Matrix metalloproteinase-9 (MMP-9), a gelatinase that degrades major components of the basal lamina, has been associated to blood–brain barrier disruption. We aimed to assess, in patients with CVT, the temporal change in serum concentrations of MMP-9 and its association with key imaging and clinical outcomes. Methods Pathophysiology of Venous Infarction—PRediction of InfarctiOn and RecanalIzaTion in CVT (PRIORITy-CVT) was a multicenter prospective cohort study of patients with newly diagnosed CVT. Serial collection of peripheral blood samples performed on day 1, 3, and 8, and standardized magnetic resonance imaging on day 1, 8, and 90. MMP-9 was quantified using enzyme-linked immunosorbent assay in 59 patients and 22 healthy controls. Primary outcomes were parenchymal brain lesion, early evolution of brain lesion, early recanalization, and functional outcome on day 90. Results CVT patients with parenchymal brain lesion had higher baseline concentrations of MMP-9 compared with controls (adjusted p = 0.001). The area under receiver operating characteristic curve value for MMP-9 for predicting brain lesion was 0.71 (95% confidence interval [CI]: 0.57–0.85, p = 0.009). Patients with venous recanalization showed early decline of circulating MMP-9 and significantly lower levels on day 8 (p = 0.021). Higher MMP-9 on day 8 was associated with persistent venous occlusion (odds ratio: 1.20 [per 20 ng/mL], 95% CI: 1.02–1.43, p = 0.030). Conclusion We report a novel relationship among MMP-9, parenchymal brain damage, and early venous recanalization, suggesting that circulating MMP-9 is a dynamic marker of brain tissue damage in patients with CVT.

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Expression Without Recognition: Contributions of the Human Amygdala to Emotional Communication

Psychological Science ◽

10.1111/1467-9280.00224 ◽

2000 ◽

Vol 11 (2) ◽

pp. 106-111 ◽

Cited By ~ 109

Author(s):

Adam K. Anderson ◽

Elizabeth A. Phelps

Keyword(s):

Social Communication ◽

Emotional Processing ◽

Emotional State ◽

Social Signals ◽

Basic Emotions ◽

The Social ◽

Emotional Appraisal ◽

Facial Expressions Of Emotion

A growing body of evidence from humans and other animals suggests the amygdala may be a critical neural substrate for emotional processing. In particular, recent studies have shown that damage to the human amygdala impairs the normal appraisal of social signals of emotion, primarily those of fear. However, effective social communication depends on both the ability to receive (emotional appraisal) and the ability to send (emotional expression) signals of emotional state. Although the role of the amygdala in the appraisal of emotion is well established, its importance for the production of emotional expressions is unknown. We report a case study of a patient with bilateral amygdaloid damage who, despite a severe deficit in interpreting facial expressions of emotion including fear, exhibits an intact ability to express this and other basic emotions. This dissociation suggests that a single neural module does not support all aspects of the social communication of emotional state.

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The Electrophysiology and Time Course of Processing Vocal Emotion Expressions

The Oxford Handbook of Voice Perception ◽

10.1093/oxfordhb/9780198743187.013.20 ◽

2018 ◽

pp. 458-472

Author(s):

Silke Paulmann ◽

Sonja A. Kotz

Keyword(s):

Time Course ◽

Emotion Processing ◽

Task Demands ◽

Emotional Communication ◽

Social Psychological ◽

Eeg Recordings ◽

The Voice ◽

Expression Processing ◽

Processing Steps ◽

Vocal Emotion

Emotional communication is a key component of human social interactions. Listeners need to rapidly decode emotionally relevant signals and adapt their behaviour accordingly. This chapter summarizes recent findings on the time course underlying vocal emotion processing, with a particular focus on suprasegmental information as expressed by the voice and intonation in speech. Evidence from both behavioural investigations and electrophysiological (EEG) recordings confirms that vocal emotion processing includes early rapid—most likely involuntary—appraisal, as well as enhanced cognitive emotional meaning evaluation. Reviewed findings also suggest that influences such as task demands, individual differences, as well as social-psychological factors can alter the identified processing steps. In short, findings suggest that emotional vocal expression processing is a multi-layered process which follows a distinct time course.

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Reflections on the Human Face

Journal of the International Neuropsychological Society ◽

10.1017/s1355617700256130 ◽

2000 ◽

Vol 6 (6) ◽

pp. 738-739

Author(s):

Steven Z. Rapcsak

Keyword(s):

Social Communication ◽

Emotional State ◽

Personality Characteristics ◽

Neural Systems ◽

Human Face ◽

Age And Gender ◽

Facial Cues ◽

The Face ◽

And Gender ◽

Genetically Determined

The significance of the human face in social interaction can hardly be overestimated. We rely primarily on facial appearance in discriminating between members of our species, but we also use the face to judge the age and gender of a person and to interpret his or her emotional state. We find certain faces pleasant or attractive, attribute personality characteristics to people such as intelligence or honesty based on physiognomy, and use facial cues to guess people's intentions and predict their behavior toward us. Similarly, we can gauge the effect of our words or actions on others by the feedback we receive from their faces. The face assumes a privileged role in social communication almost immediately after birth, suggesting that the neural systems underlying various facial behaviors are to a large extent innately specified and genetically determined.

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Analysis of aspects of quality of life in teachers' voice after discharged: longitudinal study

CoDAS ◽

10.1590/s2317-17822013000500014 ◽

2013 ◽

Vol 25 (5) ◽

pp. 486-491 ◽

Cited By ~ 5

Author(s):

Josiane Mendes Ferreira ◽

Nathalia Ferreira Campos ◽

Iara Barreto Bassi ◽

Marco Aurelio Rocha Santos ◽

Leticia Caldas Teixeira ◽

...

Keyword(s):

Longitudinal Study ◽

Social Communication ◽

Life Quality ◽

Voice Therapy ◽

Present Moment ◽

Language Therapy ◽

Positive Effects ◽

The Voice

PURPOSE: To evaluate the long-term effects of voice therapy on the life quality of teachers who were discharged or abandoned the voice therapy for dysphonia. METHODS: This was a longitudinal study based on analysis of assessments with teachers of municipal schools in Belo Horizonte, who were referred to voice therapy and were discharged or abandoned the speech-language therapy for more than six months. A total of 33 teachers in the discharged group and 20 teachers in the abandoned group were contacted by phone and invited to participate in the study by answering the Voice activity and participation profile, which was forwarded to the researchers and sent via letter. RESULTS: At the moment of the pre speech therapy, the discharged and abandoned groups were homogeneous, except in relation to daily communication parameter. Comparing the discharged group in the pre and post speech-language therapy, it was showed improvements in social communication parameter as well as in the total score. The discharged group presented worsening in self-perception parameter when comparing the average values in the post therapy and current moments, and the group abandoned presented worsening in work, social communication and total score when comparing to the average values in the pre therapy and current moments. The discharged and abandoned groups differ in the present moment in all investigated parameters. CONCLUSION: Speech-language therapy for dysphonia have long term positive effects on life quality and voice of teachers who were soon discharged from the therapy and in a period of two years on average. Teachers who have abandoned treatment and did not obtain improvement in the voice showed negative impact in life quality and voice in a time of 2 years and 2 months on average.

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