scholarly journals Effect of Channel Radius on the Molecular Communication Based on Fluorescent Nanoparticles

2021 ◽  
Author(s):  
Federico Calì ◽  
Luca Fichera ◽  
Nunzio Tuccitto
Keyword(s):  
Quantum Dots ◽  
Diffusion Coefficient ◽  
Flow Velocity ◽  
Communication Channel ◽  
Information Quality ◽  
Carbon Quantum Dots ◽  
Fluorescent Nanoparticles ◽  
Velocity Range ◽  
Molecular Communication ◽  
Theoretical Results

The effect of the communication channel size on the transport and subsequent detection of chemical messengers is investigated on millimetric and micrometric channels. The transport of the information carriers, being characterized by an advective and a diffusive contribution, was simulated by varying the flow velocity and the diffusion coefficient. Then, to evaluate the information quality, the Intersymbol Interference (ISI) between two consecutive signals at a specific release delay was estimated. This allowed us to verify that operating under micrometric channel conditions has a larger flow velocity range to obtain completely separated successive signals and smaller release delays can be used between signals. The theoretical results were confirmed by developing a prototype molecular communication platform operating under microfluidic conditions, which enables communication through fluorescent nanoparticles, namely Carbon Quantum Dots (CQDs).

scholarly journals Effect of Channel Radius on Fluorescent Nanoparticle Based Molecular Communication

Chemosensors ◽  
2022 ◽  
Vol 10 (1) ◽  
pp. 29
Author(s):  
Federico Calì ◽  
Luca Fichera ◽  
Nunzio Tuccitto
Keyword(s):  
Diffusion Coefficient ◽  
Flow Velocity ◽  
Communication Channel ◽  
Information Quality ◽  
Carbon Quantum Dots ◽  
Fluorescent Nanoparticles ◽  
Velocity Range ◽  
Molecular Communication ◽  
Fluorescent Nanoparticle ◽  
Theoretical Results

The effect of the communication channel size on the transport and subsequent detection of chemical messengers is investigated on millimetric and micrometric channels. The transport of the information carriers, being characterized by an advective and a diffusive contribution, was simulated by varying the flow velocity and the diffusion coefficient. Then, to evaluate the information quality, the Intersymbol Interference (ISI) between two consecutive signals at a specific release delay was estimated. This allowed us to verify that operating under micrometric channel conditions has a larger flow velocity range to obtain completely separated successive signals and smaller release delays can be used between signals. The theoretical results were confirmed by developing a prototype molecular communication platform operating under microfluidic conditions, which enables communication through fluorescent nanoparticles, namely Carbon Quantum Dots (CQDs).

scholarly journals Carbon Quantum Dots from Lemon Waste Enable Communication among Biodevices

Chemosensors ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 202
Author(s):  
Federico Calì ◽  
Valentina Cantaro ◽  
Luca Fichera ◽  
Roberta Ruffino ◽  
Giuseppe Trusso Sfrazzetto ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Electromagnetic Waves ◽  
Carbon Quantum Dots ◽  
Point Of View ◽  
Fluorescence Properties ◽  
Fluorescent Nanoparticles ◽  
Theoretical Point ◽  
Molecular Communication ◽  
Chemical Systems ◽  
And Diffusion

A bioinspired method of communication among biodevices based on fluorescent nanoparticles is herein presented. This approach does not use electromagnetic waves but rather the exchange of chemical systems—a method known as molecular communication. The example outlined was based on the fluorescence properties of carbon dots and follows a circular economy approach as the method involves preparation from the juice of lemon waste. The synthesis is herein presented, and the fluorescence properties and diffusion coefficient are evaluated. The application of carbon dots to molecular communication was studied from a theoretical point of view by numerically solving the differential equation that governs the phenomenon. The theoretical results were used to develop a prototype molecular communication platform that enables the communication of simple messages via aqueous fluids to a fluorescence-detecting biodevice receiver.

scholarly journals Quantifying Cytosolic Cytochrome c Concentration Using Carbon Quantum Dots as a Powerful Method for Apoptosis Detection

Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1556
Author(s):  
Cristian Silviu Moldovan ◽  
Anca Onaciu ◽  
Valentin Toma ◽  
Radu Marginean ◽  
Alin Moldovan ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Cytochrome C ◽  
Laser Scanning ◽  
A549 Cells ◽  
Carbon Quantum Dots ◽  
Laser Scanning Microscopy ◽  
Confocal Laser ◽  
Fluorescent Nanoparticles ◽  
Cyt C

Background: Cytochrome c (Cyt c) is a key biomarker for early apoptosis, and many methods were designed to detect its release from mitochondria. For a proper evaluation of these programed cell death mechanisms, fluorescent nanoparticles are excellent candidates due to their valuable optical properties. Among all classes of nanoparticles developed thus far, carbon-based quantum dots bring qualitative and efficient imaging strategies for biomedical applications as a consequence of their biocompatibility and low cytotoxicity. Methods: In this study, we synthesized carbon quantum dots smaller than 5 nm from sodium citrate and polyethylene imine. These nanoparticles were rigorously characterized, and their quenching capacity in apoptotic events was assessed in A549 cells treated with staurosporine and etoposide. For the evaluation of Cyt c release, a phenomenon directly correlated with apoptotic events, we ran a semiquantitative analysis using confocal laser scanning microscopy. Results: Carbon quantum dots were synthesized and were successfully employed for Cyt c detection by means of fluorescence microscopy. Significant drops in fluorescence intensity were observed in the case of cells treated with apoptosis-inducing therapeutic compounds compared to untreated cells, confirming Cyt c release from mitochondria to cytosol. Conclusion: Considering these results, we strongly believe this method can contribute to an indirect in vitro evaluation of apoptosis.

LUMINESCENT DETERMINATION OF SUGAR IN NATURAL HONEY

2020 ◽  
Vol 0 (4) ◽  
pp. 29-32
Author(s):  
B.M. GAREEV ◽  
◽  
A.M. ABDRAKHMANOV ◽  
G.L. SHARIPOV ◽  
◽  
...  
Keyword(s):  
Quantum Dots ◽  
Laboratory Test ◽  
Aqueous Solutions ◽  
Analytical Method ◽  
Sugar Content ◽  
Carbon Quantum Dots ◽  
Photoluminescence Intensity ◽  
Sucrose Content ◽  
Natural Honey

The photoluminescence of carbon quantum dots synthesized from natural honey and mixtures of honey and sugar has been studied. An increase in the sugar content leads to a decrease in the photoluminescence intensity without changing the shape of the luminescence spectrum of these quantum dots aqueous solutions, which is associated with a decrease in the yield of their synthesis in the sugar presence. The discovered effect can be used to detect sugar in honey. When examining five different market samples of flower honey using this method, two of them showed a significant decrease in the photoluminescence intensity. A laboratory test for compliance with GOST 19792-2017 Standard requirements established an excess of the sucrose content in these samples. Luminescent determination of sugar in honey does not require complicated equipment and can be used to develop a new analytical method for determining the sugar content in counterfeit natural honey.

Enhanced reduction of p-nitrophenol by zerovalent iron modified with carbon quantum dots

2021 ◽  
Vol 285 ◽  
pp. 119829
Author(s):  
Peng Fan ◽  
Xuanjun Zhang ◽  
Huanhuan Deng ◽  
Xiaohong Guan
Keyword(s):  
Quantum Dots ◽  
Carbon Quantum Dots ◽  
Zerovalent Iron
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