scholarly journals The Novel Coronavirus Pandemic and the State of the Epidemic in Kobe, Japan

2021 ◽  
Vol 16 (1) ◽  
pp. 84-87
Author(s):  
Noriko Nakanishi ◽  
◽  
Yoshio Iijima
Keyword(s):  
Developing Countries ◽  
The State ◽  
The Novel ◽  
Novel Coronavirus ◽  
The City

The outbreak of the novel coronavirus disease (COVID-19), caused by the SARS-CoV-2 virus, occurred in Wuhan, China in December 2019 and quickly spread to both the developed and developing countries. The virus will continue to infect humans and animals symptomatically or asymptomatically, and humans will be expected to coexist with SARS-CoV-2 by preventing infections and its spread. In this paper, we report on the occurrence of the COVID-19 epidemic in Japan, including the city of Kobe.

scholarly journals Mobility-Guided Modeling of the COVID-19 Pandemic in Metro Manila

2020 ◽  
Author(s):  
Bernhard Egwolf ◽  
O.P. Nicanor Austriaco
Keyword(s):  
The Philippines ◽  
The Novel ◽  
National Capital Region ◽  
Viral Spread ◽  
Mobility Data ◽  
National Capital ◽  
Metro Manila ◽  
The Government ◽  
Novel Coronavirus ◽  
The City

ABSTRACTCOVID-19 is a novel respiratory disease first identified in Wuhan, China, that is caused by the novel coronavirus, SARS-CoV-2. To better understand the dynamics of the COVID-19 pandemic in the Philippines, we have used real-time mobility data to modify the DELPHI Epidemiological Model recently developed at M.I.T., and to simulate the pandemic in Metro Manila. We have chosen to focus on the National Capital Region, not only because it is the nation’s demographic heart where over a tenth of the country’s population live, but also because it has been the epidemiological epicenter of the Philippine pandemic. Our UST CoV-2 model suggests that the government-imposed enhanced community quarantine (ECQ) has successfully limited the spread of the pandemic. It is clear that the initial wave of the pandemic is flattening, though suppression of viral spread has been delayed by the local pandemics in the City of Manila and Quezon City. Our data also reveals that replacing the ECQ with a General Community Quarantine (GCQ) will increase the forecasted number of deaths in the nation’s capital unless rigorous tracing and testing can be implemented to prevent a second wave of the pandemic.

The Novel Coronavirus: A Major Global Health Concern

2020 ◽  
Vol 8 (1) ◽  
Keyword(s):  
Care Staff ◽  
Health Concern ◽  
Health Care Staff ◽  
The Novel ◽  
Risk Of Infection ◽  
Inhibitory Effects ◽  
Runny Nose ◽  
Novel Coronavirus ◽  
Nucleoprotein N ◽  
The City

Today, Coronavirus (Cov) is one of the most dangerous diseases worldwide, and many people suffer from it. Coronavirus as a deadly virus was first recognized and spread in the City of Wuhan, Province of Hubei, China. This virion contains nucleocapsid, which is consists of phosphorylated nucleoprotein (N) and genomic RNA. The RNA of coronaviruses is enveloped, not fragmented, and is a positively sensitive single-stranded RNA that is known to be the largest viral genome in various sizes from 26 to 32 kV. Cov usually tends to provoke mild to severe respiratory disease. The symptoms of Cov may comprise headache, cough, fever, sore throat, runny nose, and a discomfort sensation. People with chronic diseases and health care staff are at greater risk of infection. Some compounds, such as mycophenolic acid and cyclosporine A, RNAi, and monoclonal antibodies have shown inhibitory effects against Cov. This article briefly discusses the nature, symptoms, transmission, treatment, prevention, and protection of this deadly virus.

scholarly journals A Review of Updates on Vaccines and Treatment Options for Covid-19

2021 ◽  
Vol VI (I) ◽  
pp. 1-9
Author(s):  
Naiha Tahir ◽  
Ayema Rehman ◽  
Muhammad Zain ◽  
Mubashir Rehman
Keyword(s):  
Focal Point ◽  
Treatment Options ◽  
The Novel ◽  
Wholesale Market ◽  
Current Management ◽  
Enveloped Virus ◽  
Global Pandemic ◽  
Novel Coronavirus ◽  
In The Beginning ◽  
The City

The novel Coronavirus knew as Covid 19 or SARS-CoV-2, is a newly discovered virus responsible for the huge global pandemic infecting the human race at a deadly pace. This is an RNA enveloped virus that targets the human respiratory system severely while damaging other major systems. Covid 19 pandemic is similar to the severe acute respiratory syndrome related coronavirus (SARS-CoV) endemic and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV), but this one is spreading at a fire-speed. The outbreak was known as pneumonia in the beginning; however, it became a threat later on, owing to its high contagion rate. The origin of this virus was sought to be from the seafood wholesale market, very popular in the city of Wuhan. This review has been put together to overview the disease, its etiology, clinical features and treatment methods. The focal point of this review is to highlight the current management of this disease.

scholarly journals Epidemiological Features of the Incidence of COVID-19 in Moscow in the Period from March 1 to August 31, 2020

2021 ◽  
pp. 57-62
Author(s):  
AV Ivanenko ◽  
DV Soloviev ◽  
NA Volkova ◽  
VM Glinenko ◽  
OA Smirnova ◽  
...  
Keyword(s):  
Statistical Significance ◽  
High Rate ◽  
The Novel ◽  
Upper Respiratory Tract ◽  
Epidemiological Features ◽  
Student’S T ◽  
Novel Coronavirus ◽  
Tract Infections ◽  
The City ◽  
Spearman’S Correlation

Introduction: Coronavirus (SARS-CoV-2) infection is a global healthcare and social problem due to a rapid ubiquitous spread of the virus, a high rate of complications and deaths. The disease is often asymptomatic, which can contribute to its spread, while the most common complication is the development of pneumonia with or without acute respiratory failure and respiratory distress syndrome, which are often fatal. These characteristics of the disease, along with the almost complete lack of immunity in the population around the world (before the mass spread), allowed SARS-CoV-2 to spread freely among the population of all countries. Our objective was to assess the epidemiological features of the incidence of the novel coronavirus disease (COVID-19) in the population of the city of Moscow. Materials and methods: We conducted a retrospective analysis of all confirmed COVID-19 cases, the total number of diagnostic tests for COVID-19, and the incidence of upper respiratory tract infections registered in Moscow from March 1 to August 31, 2020. The correlation analysis was performed by calculating the Spearman’s correlation coefficient and subsequent statistical significance of differences in the compared relative values (p) from the Student’s t-test. Confidence intervals were determined with the calculation of average errors of the compared variables – m(σ). Conclusion: The revealed features of the COVID-19 incidence in Moscow help establish the factors influencing the development of the epidemic process in the city and give an accurate prediction of the COVID-19 situation for the future.

scholarly journals Antiviral potential of phytoligands against chymotrypsin-like protease of COVID‐19 virus using molecular docking studies: An optimistic approach

2020 ◽  
Author(s):  
Ratish Chandra Mishra ◽  
Rosy Kumari ◽  
Shivani Yadav ◽  
Jaya Parkash Yadav
Keyword(s):  
Molecular Docking ◽  
Binding Energy ◽  
Drug Repositioning ◽  
Docking Studies ◽  
The Novel ◽  
Lead Compounds ◽  
Recent Outbreak ◽  
Novel Coronavirus ◽  
The City ◽  
Ucsf Chimera

Abstract A recent outbreak of the novel coronavirus, COVID‐19, in the city of Wuhan, Hubei province, China and its ensuing worldwide spread have resulted in lakhs of infections and thousands of deaths. As of now, there are no registered therapies for treating the contagious COVID‐19 infections, henceforth drug repositioning may provide a fast way out. In the present study, a total of thirty-five compounds including commonly used anti-viral drugs were screened against chymotrypsin-like protease (3CLpro) using SwissDock. Interaction between amino acid of targeted protein and ligands was visualized by UCSF Chimera. Docking studies revealed that the phytochemicals such as cordifolin, anisofolin A, apigenin 7-glucoside, luteolin, laballenic acid, quercetin, luteolin-4-glucoside exhibited significant binding energy with the enzyme viz. - 8.77, -8.72, -8.36, -8.35, -8.13, -8.04 and -7.87 Kcal/Mol respectively. Therefore, new lead compounds can be used for drug development against SARS‐CoV‐2 infections.

scholarly journals Coping by the healthcare workers during COVID-19 pandemic in developing countries - A review.

2020 ◽  
Vol 24 (3) ◽  
Author(s):  
Alka Chandra ◽  
Hemant Vanjare
Keyword(s):  
Developing Countries ◽  
High Risk ◽  
Healthcare Workers ◽  
The Novel ◽  
Front Line ◽  
Outbreak Response ◽  
Duty Hours ◽  
Novel Coronavirus

In December 2019, an outbreak of the novel coronavirus (COVID-19) occurred in Wuhan, China. To date, this has spread across the globe, raising a number of significant challenges for healthcare workers (HCW). They are at the front line of the outbreak response and as such are exposed to hazards including the high risk of contracting the infection. Long and irregular duty hours in very constrained environment can contribute to increased levels of stress and ultimately precipitate burnout.

scholarly journals Political Ideology and the Outbreak of COVID-19 in the United States

2020 ◽  
Author(s):  
Daniel L. Rosenfeld
Keyword(s):  
United States ◽  
Political Ideology ◽  
State Level ◽  
The United States ◽  
The State ◽  
The Novel ◽  
Unique Role ◽  
Rapid Spread ◽  
Novel Coronavirus

At the state level within the United States, did political ideology predict the outbreak of the novel coronavirus (COVID-19)? Throughout March 2020, the United States became the epicenter of the COVID-19 pandemic, recording the most cases of any country worldwide. The current research found that, at the state level within the United States, more conservative political ideology predicted delayed implementation of stay-at-home orders and more rapid spread of COVID-19. Effects were significant across two distinct operationalizations of political ideology and held over and above relevant covariates, suggesting a potentially unique role of political ideology in the United States’ COVID-19 outbreak. Considering political ideological factors may offer valuable insights into epidemiological processes surrounding COVID-19.

scholarly journals “We Need such a Space”: Residents’ Motives for Visiting Urban Green Spaces during the COVID-19 Pandemic

2021 ◽  
Vol 13 (12) ◽  
pp. 6806
Author(s):  
Shixian Luo ◽  
Jing Xie ◽  
Katsunori Furuya
Keyword(s):  
Green Space ◽  
Well Being ◽  
Green Spaces ◽  
The Novel ◽  
Important Place ◽  
Space Planning ◽  
Urban Green ◽  
Urban Green Spaces ◽  
Novel Coronavirus ◽  
The City

Since the outbreak of the Novel Coronavirus Pneumonia in 2019, several cities have been blocked to prevent the expansion of the infection. This qualitative study aimed to determine the motives of urban residents for visiting urban green spaces during the epidemic (especially within the context of the city blockade), and what might weaken these motives. In total, 47 residents (17 men and 30 women) were recruited from Chengdu, in China, to participate in interviews. A thematic analysis was used to analyze the interview data. According to the results, the motives of the respondents were divided into strong motives and weak motives. These strong motives for visiting UGS can be divided into four themes: “A place for health”, “Escape”, “Social support”, and “A safe and important place for outdoor activities”. Residents classified as the weak motive primarily considered the reasons of “Keep distance with others”, “Potential infection risk” and “Seek compensation”. The results of this study are significant for current and future urban management, green space planning, and social well-being.

scholarly journals The spatio-temporal epidemic dynamics of COVID-19 outbreak in Africa

2020 ◽  
Author(s):  
Ezra Gayawan ◽  
Olawale Awe ◽  
Bamidele M Oseni ◽  
Ikemefuna C. Uzochukwu ◽  
Adeshina Adekunle ◽  
...  
Keyword(s):  
Temporal Dynamics ◽  
Poisson Model ◽  
The Novel ◽  
African Continent ◽  
Scarce Resources ◽  
Epidemic Dynamics ◽  
Disease Patterns ◽  
Spatio Temporal ◽  
Novel Coronavirus ◽  
The City

AbstractThe novel coronavirus (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in the city of Wuhan, China in December 2019. Although, the disease appears on the African continent late, it has spread to virtually all the countries. We provide early spatio-temporal dynamics of COVID-19 within the first 62 days of the disease’s appearance on the African continent. We used a two-parameter hurdle Poisson model to simultaneously analyze the zero counts and the frequency of occurrence. We investigate the effects of important healthcare capacities including hospital beds and number of medical doctors in the different countries. The results show that cases of the pandemic vary geographically across Africa with notable high incidence in neighboring countries particularly in West and North Africa. The burden of the disease (per 100,000) was most felt in Djibouti Tunisia, Morocco and Algeria. Temporally, during the first 4 weeks, the burden was highest in Senegal, Egypt and Mauritania, but by mid-April it shifted to Somalia, Chad, Guinea, Tanzania, Gabon, Sudan, and Zimbabwe. Currently, Namibia, Angola, South Sudan, Burundi and Uganda have the least burden. The findings could be useful in implementing epidemiological intervention and allocation of scarce resources based on heterogeneity of the disease patterns.

scholarly journals Senna Makki and the COVID-19 pandemic: a reflection from Pakistan

2020 ◽  
Vol 7 (12) ◽  
pp. 5194
Author(s):  
Sahil Kumar ◽  
Ramsha Naeem ◽  
Anum Syed Tauqir Radhawi ◽  
Syed Uzair Mahmood ◽  
Zehra Batool ◽  
...  
Keyword(s):  
Social Media ◽  
Developing Countries ◽  
Treatment Options ◽  
The Novel ◽  
Misleading Information ◽  
The Public ◽  
New Variant ◽  
Herbal Medications ◽  
High Doses ◽  
Novel Coronavirus

The outbreak of the novel coronavirus (SARS-CoV-2) since December 2019 has created an unprecedented state. As it is a new variant of a virus treatment options are not only limited but require painstaking trials to confirm their effectiveness. Due to the lack of awareness in many developing countries people have started using herbal medications, used for various other diseases, to combat COVID-19. Misleading information on social media regarding “Senna Makki” has gone viral in Pakistan. However, consumption of Senna Makki is not advised as a treatment option for COVID-19 due to its many harmful associated side-effects. Although its use in other diseases is evident, trials to confirm its effectiveness against COVID-19 need to be prioritized as the public has started consuming Senna Makki in high doses and without monitored prescription.  

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