scholarly journals STUDY OF ADHERENCE TO DRUG THERAPY OF PATIENTS WITH CARDIOVASCULAR DISEASES IN DISTRICT HOSPITAL OF SMALL TOWN IN SARATOV REGION AND IN CARDIOLOGY DEPARTMENT OF UNIVERSITY CLINIC IN SARATOV

2018 ◽  
Vol 14 (3) ◽  
pp. 337-343
Author(s):  
Yu. V. Bulaeva ◽  
E. A. Naumova ◽  
O. N. Semenova
Keyword(s):  
Drug Therapy ◽  
Cardiovascular Diseases ◽  
Small Town ◽  
District Hospital ◽  
University Hospital ◽  
Saratov Region ◽  
Long Term Treatment ◽  
The University ◽  
Attending Physician

Aim. To study the relation of various factors with adherence to long-term drug therapy in patients with cardiovascular diseases in district hospital of small town in Saratov Region and patients from clinical hospital of Saratov medical university.Material and methods. The hospitalized patients with cardiovascular diseases were included into the prospective study of long-term adherence to treatment. Questioning of patients with the determination of the attitude of respondents to their health, the desire to receive information about the disease, the level of awareness of the therapy, the degree of participation in the treatment process, the nature of the relationship with the attending physician was performed. A year after discharge, control calls were made to patients to learn whether the patient was continuing treatment prescribed a year ago in the hospital. The data on patient adherence in both hospitals were analyzed.Results. 108 patients in the district hospital (58% of selected patients) and 70 in the Saratov hospital (33% of selected patients) responded to all questions in the questionnaire during hospitalization. Successful reaching by phone 12 months after discharge from the hospital took place in 74 patients of the small town and 40 patients of the regional center. The continuation of treatment was found in 28 (38%) and 24 (50%) patients, respectively. Patients who continued treatment significantly differed from those, who stopped therapy, by presence of myocardial infarction in anamnesis [14 (78%) patients in the university hospital and 6 (60%) patients in the district hospital; p<0.01] as well as acute cerebrovascular accident [6 (78%) patients in the university hospital and 4 (75%) patients in the district hospital; p<0.05] and stable angina class I-III [22 (61%) patients in Saratov and 28 (44%) patients in the small town; p<0.01]. Adherence to recommendations after 12 months was found in patients who considered that doctor or relatives were responsible for their health (6 patients in Saratov and 12 – in the small town; p<0.05) and believed that attending physician determines the portion of information provided to the patient [20 (60%) patients of the district hospital and 11 (63%) patients in the university clinic; p<0.05 for university clinic].Conclusion. The adherence to long-term treatment after discharge remained low and did not exceed 50% among patients in both groups. The paternalistic model continued to dominate in the doctor-patient interconnection system.

scholarly journals Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlation

2021 ◽  
Author(s):  
Katja Evert ◽  
Thomas Dienemann ◽  
Christoph Brochhausen ◽  
Dirk Lunz ◽  
Matthias Lubnow ◽  
...  
Keyword(s):  
Macrophage Activation Syndrome ◽  
Macrophage Activation ◽  
Fungal Infections ◽  
Diffuse Alveolar Damage ◽  
Fungal Species ◽  
Term Treatment ◽  
University Hospital ◽  
Long Term Treatment ◽  
The University

AbstractBetween April and June 2020, i.e., during the first wave of pandemic coronavirus disease 2019 (COVID-19), 55 patients underwent long-term treatment in the intensive care unit at the University Hospital of Regensburg. Most of them were transferred from smaller hospitals, often due to the need for an extracorporeal membrane oxygenation system. Autopsy was performed in 8/17 COVID-19-proven patients after long-term treatment (mean: 33.6 days). Autopsy revealed that the typical pathological changes occurring during the early stages of the disease (e.g., thrombosis, endothelitis, capillaritis) are less prevalent at this stage, while severe diffuse alveolar damage and especially coinfection with different fungal species were the most conspicuous finding. In addition, signs of macrophage activation syndrome was detected in 7 of 8 patients. Thus, fungal infections were a leading cause of death in our cohort of severely ill patients and may alter clinical management of patients, particularly in long-term periods of treatment.

scholarly journals Psychosocial emergency care in times of COVID-19: the Essen University Hospital concept for corona-infected patients, their relatives, and medical staff

2020 ◽  
Author(s):  
Vanessa Rentrop ◽  
Johanna Sophie Schneider ◽  
Alexander Bäuerle ◽  
Florian Junne ◽  
Nora Dörrie ◽  
...  
Keyword(s):  
Medical Staff ◽  
Online Training ◽  
University Hospital ◽  
High Psychological Distress ◽  
Increased Risk ◽  
Psychosocial Emergency ◽  
Low Threshold ◽  
Long Term Consequences ◽  
The University

Abstract Due to the SARS CoV-2-virus (COVID-19), anxiety, distress, and insecurity occur more frequently. In particular, infected individuals, their relatives, and medical staff face an increased risk of high psychological distress as a result of the ongoing pandemic. Thus, structured psychosocial emergency concepts are needed. The University hospital of Essen has taken up this challenge by creating the PEC concept to reduce psychosocial long-term consequences for infected patients, relatives, and medical staff at the university hospital. The concept includes professional medical as well as psychological support to convey constructive coping strategies and the provision of adequate tools such as the low-threshold online training program (CoPE It), which is accessible via the webpage www.cope-corona.de.

Rotigotine use in long-term treatment of restless legs syndrome: Experience in General University Hospital of Castellon

2013 ◽  
Vol 14 ◽  
pp. e251-e252
Author(s):  
P. Ruiz-Elena ◽  
J. Pinzon-Martinez ◽  
A. Gomis-Devesa ◽  
I. Barreda-Altaba ◽  
J. Ortega-Albas ◽  
...  
Keyword(s):  
Restless Legs Syndrome ◽  
Term Treatment ◽  
University Hospital ◽  
Restless Legs ◽  
Long Term Treatment

scholarly journals Pulmonary and Meningeal Cryptococcosis after Corticosteroid Therapy for Autoimmune Hepatitis: Coexistence of Cryptococci within Pulmonary Cancer Nodule

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Takashi Yuri ◽  
Ayako Kimura ◽  
Katsuhiko Yoshizawa ◽  
Yuko Emoto ◽  
Yuichi Kinoshita ◽  
...  
Keyword(s):  
Autoimmune Hepatitis ◽  
Corticosteroid Therapy ◽  
Pulmonary Nodule ◽  
Cryptococcal Meningitis ◽  
Methicillin Resistance ◽  
Lower Lobe ◽  
University Hospital ◽  
Fungal Culture ◽  
Long Term Treatment

A case of autoimmune hepatitis complicated with pulmonary and meningeal cryptococcosis during long-term treatment with corticosteroid is reported. An 84-year-old woman who received long-term corticosteroid therapy (40 mg/day prednisolone for two years) for autoimmune hepatitis developed a headache, slight fever, and anorexia and was diagnosed with cryptococcal meningitis two months prior to hospital admission. Due to deterioration of her condition, the patient was transferred to our university hospital. After admission, a pulmonary nodule 1 cm in diameter was noticed in the patient’s right lower lobe. Cryptococcal meningitis was diagnosed as positive for cryptococcal antigen from both serum and cerebrospinal fluid (CSF) as well as the growth ofCryptococcus neoformans(C. neoformans) in fungal culture. A combination therapy of amphotericin B and flucytosine was started, and the corticosteroid therapy was gradually reduced and finally discontinued. In addition to continuous cryptococcal infection, complications ofPseudomonas aeruginosaand methicillin-resistanceStaphylococcus aureusinfection caused death after a 2-month hospitalization. Autopsy disclosed encapsulated yeast in the lungs and subarachnoid space characteristic ofCryptococcus. The pulmonary nodule was found to be squamous cell carcinoma coexisting withC. neoformanswithin and around the cancer cell nests.

Long-term treatment results for nasopharyngeal carcinoma: The Sahlgrenska University Hospital experience

2007 ◽  
Vol 46 (6) ◽  
pp. 817-827 ◽  
Author(s):  
Zahra Taheri-Kadkhoda ◽  
Thomas Björk-Eriksson ◽  
Karl-Axel Johansson ◽  
Claes Mercke
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Term Treatment ◽  
University Hospital ◽  
Treatment Results ◽  
Hospital Experience ◽  
Long Term Treatment

scholarly journals Chinese Herbal Medicine on Dyslipidemia: Progress and Perspective

2014 ◽  
Vol 2014 ◽  
pp. 1-11 ◽  
Author(s):  
Ming Guo ◽  
Yue Liu ◽  
Zhu-Ye Gao ◽  
Da-zhuo Shi
Keyword(s):  
Cardiovascular Diseases ◽  
Chinese Herb ◽  
Term Treatment ◽  
Lipid Lowering ◽  
Favorable Effect ◽  
Beneficial Effects ◽  
Long Term Treatment ◽  
Lipid Lowering Agents ◽  
Hypolipidemic Drugs

Dyslipidemia is an independent risk factor of cardiovascular diseases. The statins are a milestone in the primary and second prevention of cardiovascular diseases and significantly improved its prognosis. Along with the long-term treatment with statins in combination with other hypolipidemic drugs or alone, its safety has attracted a particular attention in clinic, such as the elevation of transaminase and rhabdomyolysis, which have raised an idea of developing the other types of lipid-lowering agents from botanic materials. Traditional Chinese medicine (TCM) has been used in clinical practice for more than 2000 years in China and showed some beneficial effects for human health and many diseases. Recently, many studies demonstrated a favorable effect of TCM for treating dyslipidemia; however, its mechanism remains unclear or totally unknown. The progress and perspective of studies on dyslipidemia with single Chinese herb and its monomers or effective extracts during the past 10 years are discussed in the present review.

Incidence of bone fracture in Japanese patients receiving long-term hormone therapy for prostate cancer.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e16098-e16098
Author(s):  
Hiroji Uemura ◽  
Hideo Fusayasu ◽  
Shinji Ohtake ◽  
Narihiko Hayashi ◽  
Yumiko Yokomizo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Retrospective Study ◽  
Gnrh Agonist ◽  
Hormonal Therapy ◽  
Bone Fracture ◽  
Bone Fractures ◽  
Japanese Patients ◽  
University Hospital ◽  
Long Term Treatment

e16098 Background: For patients with advanced prostate cancer, long-term treatment of androgen deprivation has been conventionally performed. Among the adverse events such as hormonal therapy, bone fracture due to osteoporosis or metastatsis is one of indispensable events. We assessed the frequency of bone fractures in Japanese patients received hormonal therapy. Methods: Between 2000 and 2010, 1,108 Japanese patients were treated with hormonal therapy including GnRH agonist plus anti-androgens or GnRH agonist alone at Yokohama City University Hospital. Of those patients, 48 patients (4.3%) had bone fractures during their treatment. In this retrospective study, we examined the association of bone fracture with the long-term hormonal therapy by investigating the duration of hormonal therapy, fracture sites, and the occurrence of fracture in castration resistant prostate cancer (CRPC) patients. Results: The median age of the patients with fracture was 77 (60-85) years; the median duration from the start of hormonal therapy to fracture was 29.4 (5.4-110.4) months. Eight patients with CRPC had pathological fractures at bone metastases. With respect of fracture sites, 22 patients (46%) had spinal fractures and 10 patients (21%) had fracture of lower legs. Of 8 CRPC patients, 7 patients had spinal fracture after long-term hormonal therapy (median: 38.6 months, range: 15.7-99.1 months). Conclusions: Japanese patients with prostate cancer treated with hormonal therapy have lower risk for bone fracture compared with those in western countries and USA, and interestingly, it is recognized that vertebral body is vulnerable to fracture in Japanese, especially in CRPC patients treated for long-term hormonal therapy. Because bone fracture in patients with prostate cancer endanger their prognosis, the bone management how to prevent bone fracture is very important during hormonal therapy. For the purpose of it, more detailed analysis in this retrospective study should be required.

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