scholarly journals Hyperuricemia as a possible risk factor for abnormal lipid metabolism in the Chinese population: a cross-sectional study

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Shaohong Zhang ◽  
Yingchai Zhang ◽  
Shuangjie Lin ◽  
Shuguang Zhang ◽  
Mingshan Qiu
Keyword(s):  
Risk Factor ◽  
Lipid Metabolism ◽  
Chinese Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Abnormal Lipid Metabolism

scholarly journals Visceral Fat is Better Related To Liver Function and Lipid Metabolism Than Body Mass Index and Waist Circumference: A Cross-Sectional Study

2021 ◽  
Author(s):  
Haiteng Zhou ◽  
Guiju Sun ◽  
Youwen Pan ◽  
Bin Wang ◽  
Wei Wang ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Risk Factor ◽  
Lipid Metabolism ◽  
Waist Circumference ◽  
Liver Function ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Lipid Metabolism Disorder ◽  
Cross Sectional ◽  
Metabolism Disorder

Abstract Objective: The role of visceral fat area (VFA) in the metabolism of lipid and liver function was not known. To compare and evaluate the correlation of VFA, waist circumference (WC) and Body mass index (BMI) measured by Bioelectrical impedance (BIA) in terms of lipid metabolism and liver function. Receiver operating characteristic curve (ROC curve), optimum cut-off points and odds ratio (OR) for liver function and lipid metabolism variables were recommended.Methods: A cross-sectional study was conducted on the subjects with the diagnose of obesity, including normal, overweight and obesity groups Direct Segmental Multi-Frequency Biolectrical Impedance technology was used to analysze body composition and biochemical indicators were tested. Participants were divided into normal and unnormal groups by lipid and liver indicators, cut off value of VFA and related variables was calculated by ROC analysis and multiple logistic regression analysis were conducted. Results: Ninety-five participants were enrolled in this study, fifty-seven (60%) were male, and the average age was thirty-four years old. Compared with normal group, high density lipoprotein (HDL) and low density lipoprotien (LDL) disorder groups have a higher VFA (normal HDL group 87.3cm2< unnormal HDL group 115.8cm2; normal LDL group 90.5cm2< unnormal LDL group 109.0cm2, p<0.05). VFA was higher in the lactate dehydrogenase (LDH) disorder group than in the normal, and the difference was significant (144.6cm2>96.2cm2, p=0.016). BMI, WC and VFA values was manifested positively correlated to glutamic oxaloacetic transaminase (AST) and alanine aminotransferase (ALT), respectively. Area under the curve (AUC) of VFA was over than 0.7 revealed great ability of related to lipid HDL metabolism (p=0.004). VFA (AUC= 0.701, 95% CI 0.577-0.826, p =0.004) provides a better diagnostic accuracy to distinguish between HDL disorder and normal groups. The optimal cut-off value for VFA was 80.2cm2 with 81.3% sensitivity and 56.8% specificity. For LDH disorder, a cut-off value of VFA 125.3 cm2 shows a sensitivity of 83.3% and specificity of 78.9% (AUC=0.792, 95% CI 0.595-0.989, p=0.019). The risk of lipid metabolism disorder and liver dysfunction were explored, and Multivariate analysis showed that VFA>80.2cm2 (OR=2.81, p=0.034) was a significantly risk factor related to HDL disorder and VFA>125.3cm2 (OR=18.75, P=0.01) was the risk factor for LDH disorder. While, WC and BMI wasn’t in the regression equation.Conclusion: VFA was more reliable and related to the lipid metabolism and liver function. VFA could be used as an independent indicator for the evaluation of the risk lipid metabolism disorder and liver dysfunction.

Eyelid Dermatitis and Contact Sensitization to Nickel: Results from an Italian Multi-Centric Observational Study

2019 ◽  
Vol 19 (1) ◽  
pp. 38-45 ◽  
Author(s):  
Alessandro Borghi ◽  
Monica Corazza ◽  
Elisa Maietti ◽  
Cataldo Patruno ◽  
Maddalena Napolitano ◽  
...  
Keyword(s):  
Risk Factor ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Contact Sensitization ◽  
Main Risk Factor ◽  
Nickel Allergy ◽  
Cross Sectional ◽  
Triggering Factor ◽  
Irritant Action ◽  
Allergic Contact

Background: Due to the sensitizing constituents of eye cosmetics, allergic contact dermatitis is considered a frequent cause of eyelid dermatitis. An association between eyelid dermatitis and nickel contained in make-ups remains controversial. Objective: The study aimed to assess the association between nickel allergy, the use of pigmented makeup products and self-reported eyelid dermatitis. Method: This multi-centric, cross-sectional study enrolled 165 women sensitized to nickel (patients) and 103 women without intolerance to metals (controls). We recorded: demographics, atopy, use of pigmented eye cosmetics (mascara, eyeshadow, eyeliner, eyebrow pencil), and previous eyelid dermatitis. Among the patients, any co-sensitization to cosmetics or metals was recorded. Results: 87.3% of the patients and 91.3% of the controls reported their use of eye make-up; 44.9% and 52.4%, respectively, reported previous episodes of eyelid dermatitis, without significant differences. The occurrence of eyelid dermatitis was significantly associated with the use of eye make-up products, both in general and considering each product separately. Age, atopy, or co-sensitization to other metals or cosmetics did not affect the occurrence of eyelid dermatitis. Conclusion: Nickel allergy should not be considered the main risk factor for eyelid dermatitis. The use of pigmented eye make-up may be a triggering factor for eyelid dermatitis, probably due to an irritant action.

scholarly journals Combined effect of hypertension and hyperuricemia on ischemic stroke in a rural Chinese population

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Peng Sun ◽  
Mengqi Chen ◽  
Xiaofan Guo ◽  
Zhao Li ◽  
Ying Zhou ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Missing Data ◽  
Chinese Population ◽  
Joint Effect ◽  
Cross Sectional Study ◽  
Combined Effect ◽  
Sectional Study ◽  
Cross Sectional ◽  
Current Smoking ◽  
Positive Correlations

Abstract Background To investigate the combined effect of hypertension and hyperuricemia to the risk of ischemic stroke in a rural Chinese population. Methods The cross-sectional study was conducted from 2012 to 2013 in a rural area of China. After exclusion for missing data, we finally included 11,731 participants into analysis. Results After adjusting for age, current smoking, current drinking, BMI, TG, HDL-C and eGFR, hypertension was significantly associated with ischemic stroke in men (OR: 2.783, 95% CI: 1.793, 4.320) and in women (OR: 4.800, 95% CI: 2.945, 7.822). However, hyperuricemia was significantly associated with ischemic stroke only in women (OR: 1.888, 95% CI: 1.244, 2.864). After full adjustment, participants with both hypertension and hyperuricemia had 8.9 times higher risk than those without them. Finally, the interaction between hypertension and hyperuricemia was statistically significant only in women rather than in men after full adjustment. Conclusions This study demonstrated the positive correlations between hypertension, hyperuricemia and ischemic stroke. Our study also demonstrated the joint effect between hypertension and hyperuricemia towards ischemic stroke only in women, not in men.

scholarly journals Correction to: Psoriasis as risk factor for non-ischemic dilated cardiomyopathy: a population-based cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Abbas Alshami ◽  
Nasam Alfraji ◽  
Steven Douedi ◽  
Swapnil Patel ◽  
Mohammad Hossain ◽  
...  
Keyword(s):  
Risk Factor ◽  
Dilated Cardiomyopathy ◽  
Population Based ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Ischemic Dilated Cardiomyopathy

An amendment to this paper has been published and can be accessed via the original article.

scholarly journals BMI, waist to height ratio and waist circumference as a screening tool for hypertension in hospital out patients: a cross-sectional study

2020 ◽  
Author(s):  
Rajan Shrestha ◽  
Bijay Khatri ◽  
Madan P. Upadhyay ◽  
Janak R. Bhattarai ◽  
Manish Kayastha ◽  
...  
Keyword(s):  
Risk Factor ◽  
Waist Circumference ◽  
Low Income ◽  
Cross Sectional Study ◽  
Anthropometric Measurement ◽  
Sectional Study ◽  
Height Ratio ◽  
Cross Sectional ◽  
Obesity And Overweight ◽  
Waist To Height Ratio

Abstract BackgroundObesity has become a global epidemic and an important risk factor for non-communicable diseases. Earlier thought to be a problem of developed world, it has now become a problem of low- and middle-income countries like Nepal. In absence of a routine surveillance or a registry system, the actual burden and trend of obesity in Nepal is unknown. Obesity and overweight are recognized risk factors for hypertension and associated with cardiovascular disease. The aim of the study was to find out burden of obesity, using three commonly employed metrics in hospital outpatient setting of a low-income country as predictors of hypertension, and compare ability of different anthropometric measurements through a non-inferiority study to predict hypertension.MethodsThis cross-sectional study was conducted among 40-69 years outpatients in a tertiary Eye and ENT hospital in a semi-urban area of Nepal among randomly selected 2,256 participants from 6,769 outpatients who were evaluated in Health Promotion and risk factor screening service. We did correlation analysis to determine the relationship between anthropometric measurement and blood pressure. The area under the Receiver Operating characteristic curve of Body Mass Index (BMI), Waist to Height Ratio (WHtR) and Waist Circumference (WC) was calculated and compared. ResultsThe prevalence of obesity and overweight by BMI was 16.09% and 42.20% respectively; by Waist-to-Height-Ratio was 32.76% which is two times higher than obesity measured by BMI. High waist circumference was observed among 66.76% participants. Female participants had greater prevalence of high WC (77.46%) than male (53.73%) (p<0.001). Prevalence of hypertension and pre-hypertension was 40.67% and 36.77% respectively. The areas under the curve were significantly higher than 0.5 for BMI (0.593), WHtR (0.602) and WC (0.610).ConclusionWaist circumference correlated well with obesity and hypertension. It also had higher predicting ability than WHtR and BMI to predict hypertension. Waist circumference thus proved to be non-inferior to two other commonly used metrics. It proved superior in detecting obesity in female. This simple and inexpensive tape measurement may play an important role in future diagnosis of obesity and prediction of HTN in resource constrained settings of developing countries.

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