scholarly journals Berat Lahir dan Kelangsungan Hidup Neonatal di Indonesia

2012 ◽  
Vol 7 (1) ◽  
pp. 8
Author(s):  
Demsa Simbolon
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cumulative Probability ◽  
Low Birth Weight Infants ◽  
Normal Birth ◽  
Cohort Design ◽  
Low Weight ◽  
High Prevalence ◽  
Maternal Parity ◽  
Single Birth

Angka kematian neonatal Indonesia menduduki peringkat ke-10 tertinggi di dunia disebabkan kejadian bayi dengan berat badan lahir rendah (BBLR) yang tinggi. Penelitian ini bertujuan untuk mengetahui pengaruh berat lahir terhadap kelangsungan hidup neonatal. Penelitian dengan desain studi kohort retrospektif ini menggunakan sumber data sekunder Survei Demografi Kesehatan Indonesia tahun 2007. Sampel meliputi 11.748 bayi yang memenuhi kriteria anak terakhir lahir hidup, lahir tunggal, dan saat wawancara berumur minimal 28 hari. Probabilitas kumulatif kelangsungan hidupneonatal di Indonesia adalah 98,49% dan cenderung semakin rendah sesuai dengan berat lahir, pada neonatal dengan berat lahir rendah adalah 95,68% dan neonatal berat lahir sangat rendah adalah 89,83%. Berat lahir berinteraksi dengan paritas ibu. Artinya, pengaruh berat lahir terhadap kelangsungan hidup neonatal berbeda berdasarkan paritas ibu. Bayi BBLR dari ibu paritas multipara dan grande multipara berisiko 2,9 kali dan 3,9 kali untuk mengalami kematian pada periode neonatal dibandingkan bayi lahir dengan berat normal. Disarankan untuk melakukan intervensi dini mencegah bayi lahir BBLR dan penanganan intensif terhadap bayi lahir BBLR.Kata kunci: Berat lahir, kelangsungan hidup neonatal, paritas ibuAbstractNeonatal mortality rate in Indonesia was ranked as 10th highest in the world because of high prevalence of infants low birth weight. This research used Indonesia Demographic and Health Survey 2007 data with retrospective cohort design. The purposes of the research are to measure the probability ofneonatal survival according to birth weight and to identify effect of birth weight on neonatal survival. The number of sample is 11.748 infants with inclusion criteria born alive, single birth, and at least 28 days old when interviewed.The study found the cumulative probability of neonatal survival in Indonesia was 98,49% and getting lower according to birth weight, at neonatal with low birth weight is 95,68% and 89,83% at neonatal with very low weight. Birth weight modification related to maternal parity, so that the influence of birth weight on neonatal survival depent on the maternal parity. Low birth weight infants of multiparous and grandemultiparous maternal parity risk 2,9 and 3,9 times experienced death in the neonatal period compared with normal birth weight. Early interventions to prevent low birth weight and intensive care to infants with low birth weight are suggested.Keywords: Birth weight, neonatal survival, maternal parity

scholarly journals A Systematic Review and Meta-analysis on the Prevalence of Low Birth Weight Infants in Iran

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Maryam Sabbaghchi ◽  
Rostam Jalali ◽  
Masoud Mohammadi
Keyword(s):  
Systematic Review ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Meta Analysis ◽  
Knowledge Network ◽  
Low Birth Weight Infants ◽  
Policy Makers ◽  
Total Prevalence ◽  
High Prevalence ◽  
The Difference

Background. Low birth weight is a significant index for survival, intrauterine growth, and mortality in infants. Thus, this study is aimed at determining the prevalence of low birth weight in Iranian infants through a systematic review and meta-analysis. Methods. This study was performed by meta-analysis from January 2000 to December 2019. The studies relevant to the topic have been obtained through search in databases of Scopus, ScienceDirect, SID, Magiran, Barakat Knowledge Network System, Medline (PubMed), and Google Scholar. Heterogeneity of the studies has been assessed by the I 2 index, and data analysis was done using Comprehensive Meta-Analysis software. Results. By investigating 14 articles and 93924 infants, the total prevalence of low birth weight in infants in Iran was achieved at 8.5% (95% CI: 7.3-9.9%) according to the meta-analysis; the most prevalence of low birth weight was in infants in Hamedan at 19.1% (95% CI: 21.2-17.2%) in 2007, and the lowest prevalence of low birth weight was in infants in Tonekabon at 4.2% (95% CI: 3.4-5.2%) in 2005, and also, by increasing the sample size, the prevalence of low birth weight increases, by which the difference is statistically significant ( P < 0.05 ). Conclusion. Due to the high prevalence of low birth weight in infants in Iran, health policy-makers must take effective attempts in order to reduce it in infants.

scholarly journals Adiposity rebound in very-low-birth-weight infants

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Koryo Nakayama ◽  
Go Ichikawa ◽  
Junko Naganuma ◽  
Satomi Koyama ◽  
Osamu Arisaka ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Repeated Measures ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Normal Birth ◽  
Adiposity Rebound ◽  
Repeated Measures Analysis ◽  
One Year ◽  
Medical University

Abstract Objectives Adiposity rebound (AR) refers to an increase in body mass index (BMI) after a nadir. Early AR, in which AR occurs earlier than five years old, is a risk factor for future obesity and metabolic syndrome, but has not been widely studied in very-low-birth-weight infants (VLBWIs). Methods The subjects were VLBWIs born in Dokkyo Medical University NICU from January 2008 to December 2010. Height and weight measured at birth and at intervals until seven years old were obtained from medical records. The lowest BMI after one year of age was used for the age of AR. The subjects were divided into those with early and normal AR (<5 and ≥5 years old). BMI percentile at age seven years was compared using the interquartile range (IQR). Changes in BMI were evaluated by repeated measures analysis of variance (ANOVA). Results There were 38 early AR cases and 62 normal AR cases, giving a prevalence of early AR similar to that in infants with normal birth weight. BMI percentile at age seven years was significantly higher in early AR cases than in normal AR cases (44.6 [IQR: 21.0–79.2] vs. 14.4 [IQR: 3.8–40.8] kg/m2). Changes in BMI were also significantly higher in early AR cases (p=0.024 by ANOVA). Conclusions Early AR in VLBWIs is a predictor of future obesity.

Characterization of the role of microRNA-517a expression in low birth weight infants

2013 ◽  
Vol 4 (6) ◽  
pp. 522-526 ◽  
Author(s):  
G. Y. Song ◽  
W. W. Song ◽  
Y. Han ◽  
D. Wang ◽  
Q. Na
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Placental Tissue ◽  
Maternal Serum ◽  
Trophoblast Invasion ◽  
Normal Birth Weight ◽  
Serum Samples ◽  
Low Birth Weight Infants ◽  
Human Trophoblast ◽  
Normal Birth

The purpose of this study was to analyze the expression of the placenta-specific microRNA miR-517a in maternal serum and in placental tissue from low birth weight newborns and try to detect the effects of miR-517a expression on invasion potential of trophoblasts. Placental tissue and maternal serum were collected from both low birth weight newborns (n = 10) and normal birth weight newborns (n = 20). Expression of miR-517a was assessed in placenta and serum samples by real-time qRT-PCR. In addition, human trophoblast HTR8/SVneo cells were transfected with a miR-517a 2′-O-methyl oligonucleotide or a negative control RNA, and invasion was measured using transwell migration assays. Expression of miR-517a was significantly increased in placentas from low birth weight newborns (61.79 ± 23.06) in comparison with those of normal birth weight newborns (5.01 ± 1.97; P < 0.05). The expression of miR-517a was also increased in maternal serum isolated from the low birth weight newborn (25.78 ± 8.69) compared with the normal birth weight newborn (3.21 ± 1.07; P < 0.05). Overexpression of miR-517a significantly inhibited invasion of HTR8/SVneo cells (P < 0.05). These data indicate that miR-517a overexpression could potentially lead to low birth weight, likely through the inhibition of trophoblast invasion.

Investigating the changes in amino acid values in premature infants: a pilot study

2018 ◽  
Vol 31 (4) ◽  
pp. 435-441 ◽  
Author(s):  
Yuqi Yang ◽  
Bin Yu ◽  
Wei Long ◽  
Huaiyan Wang ◽  
Ying Wang ◽  
...  
Keyword(s):  
Birth Weight ◽  
Amino Acid ◽  
Low Birth Weight ◽  
Premature Infants ◽  
Gestational Age ◽  
Control Group ◽  
Specific Reference ◽  
Reference Ranges ◽  
Low Birth Weight Infants ◽  
Normal Birth

AbstractBackground:The objective of the study was to investigate the changes in amino acid (AAs) values in premature infants.Methods:A total of 2159 premature and/or low birth weight infants were recruited for this study. They were divided into three groups: premature infants with normal birth weight (G1), simple low birth weight infants (G2) and premature combined with low birth weight infants (G3). The tandem mass spectrometry technique was used to detect the levels of 11 AAs in neonatal blood.Results:Compared with normal babies, there were eight and five AAs that significantly changed in G1 and G2, respectively. It was worth noting that the changes greatly exacerbated when the babies were both premature and of low birth weight. All the levels of AAs demonstrated significant changes in G3 compared with the normal control group (G4). With the increase in gestational age, the AAs in premature infants tended to the levels in normal newborns. Meanwhile, there was a correlation between AAs and birth weight. Four AAs significantly changed with the increase in body weight. Among normal newborns, the levels of AAs in girls were significantly higher than in boys. However, if the newborns were premature or had low birth weight, the differences between AA values and sexual distinction would decrease. In the end, we established the specific reference ranges of AAs for premature and/or low birth weight infants.Conclusions:There were significant differences in AAs in the premature and/or low birth weight infants. Gestational age and birth weight were two important factors inflecting the AAs metabolism.

The High Prevalence of Plasmid-Mediated Quinolone Resistance Among Very Low Birth-Weight Infants in Poland

2015 ◽  
Vol 21 (4) ◽  
pp. 391-397 ◽  
Author(s):  
Agnieszka Chmielarczyk ◽  
Monika Pobiega ◽  
Christophe de Champs ◽  
Jadwiga Wojkowska-Mach ◽  
Anna Rozanska ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Quinolone Resistance ◽  
Low Birth Weight Infants ◽  
High Prevalence

scholarly journals Factors Associated with The Incidence of Low Birth Weight

2021 ◽  
Vol 5 (2) ◽  
pp. 81-87
Author(s):  
Eka Rati Astuti
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Maternal Age ◽  
Secondary Data ◽  
Chi Square ◽  
Control Approach ◽  
Factors Associated ◽  
Normal Birth ◽  
Maternal Parity ◽  
Internal And External Factors

Low birth weight (LBW) is one of the causes of infant mortality. LBW babies can be caused by internal and external factors. This research aims to determine the factors associated with the incidence of low birth weight. This research is a retrospective study with a case control approach. The population is all mothers who gave birth in Puskemas Kayu Kunyit in South Bengkulu Regency throughout 2019, as many as 129 people, consisting of 14 babies with LBW and 115 babies with normal birth weight. The sample of this study was 28 people consisting of 14 babies who experienced LBW and 14 babies who were not LBW. Secondary data were obtained from maternal cohort and infant cohort and cases of data the incidence of low birth weight and the risk of pregnant women. Analysis of data using statistical test Chi-Square with a 95% confidence level. The analysis shows that the factors of low birth weight are maternal age (?=0.002), maternal parity (?=0.006), and pregnancy distance (?=0.02). In conclusion, factors associated with the incidence of low birth weight are maternal age, maternal parity, and pregnancy distance in the Puskesmas Kayu Kunyit.

Free triiodothyronine measured in dried blood spots from normal, low-birth-weight, and hypothyroid neonates.

1988 ◽  
Vol 34 (12) ◽  
pp. 2448-2451 ◽  
Author(s):  
D Laroche ◽  
F Lemonnier ◽  
J F Viel ◽  
G Travert ◽  
Y Fernandez
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Dried Blood Spots ◽  
Serum Samples ◽  
Free Triiodothyronine ◽  
Low Birth Weight Infants ◽  
Neonatal Hypothyroidism ◽  
Blood Samples ◽  
Low Weight ◽  
The Mean

Abstract Free triiodothyronine (FT3) has rarely been studied in neonates, primarily because of obvious problems in obtaining serum samples from neonates for research purposes. We adapted an analog radioimmunoassay for measuring FT3 in dried blood samples and used it to assay 361 samples selected from those collected for the screening for neonatal hypothyroidism. The mean FT3 concentration in healthy neonates on the fourth postpartum day is 2.55 pmol per liter of whole blood (SD 0.78 pmol/L, n = 145), the same as in healthy adults. Low-birth-weight infants have a decreased concentration of FT3, and this decrease is much greater in premature neonates than in infants at low weight for gestational age. In six hypothyroid newborns, the FT3 concentration was normal or increased, clearly indicating that FT3 assay is not a diagnostic tool for hypothyroidism. FT3 was barely detectable in one case of congenital galactosemia.

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