scholarly journals Successful Removal of Cranial Migrated Intravitreal Perfluorocarbon through A Lumbar Puncture

2020 ◽  
Author(s):  
Lin Chen ◽  
Zhongheng Zhang ◽  
Qing Wang ◽  
Hongying Ni
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Extracorporeal Membrane Oxygenation ◽  
Lumbar Puncture ◽  
Subarachnoid Space ◽  
Sudden Onset ◽  
Neurogenic Pulmonary Edema ◽  
Ocular Surgery ◽  
Case Presentation ◽  
Successful Removal

Abstract Background: Perfluorocarbon migrating into subarachnoid was very rare let alone its further removing from central nervous system. Case presentation: We report a case of migration of intravitreal perfluorocarbon into cranial space and further removed through a lumbar puncture treatment. The patient showed a sudden onset of hypoxemia and hypotension during an ocular surgery, which was highly suspected as neurogenic pulmonary edema caused by the migrated perfluorocarbon. The patient's symptoms improved after extracorporeal membrane oxygenation (ECMO). The perfluorocarbon gradually descended through subarachnoid space to lumbar cisterna and finally drained by a lumbar puncture. Conclusions: Perfluorocarbon could enter the cranial space during ocular surgery and threaten the life of patient. Further migrating through subarachnoid space provide the opportunity to remove it.

ACUTE POISONING ASSOCIATED WITH INHALATION OF MERCURY VAPOR

PEDIATRICS ◽  
1958 ◽  
Vol 22 (4) ◽  
pp. 675-688
Author(s):  
Fred T. Matthes ◽  
Rudolph Kirschner ◽  
Martha D. Yow ◽  
James C. Brennan
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Interstitial Pneumonitis ◽  
Laboratory Tests ◽  
Mercury Vapor ◽  
Acute Poisoning ◽  
Mercury Content ◽  
Sudden Onset ◽  
Pathologic Features ◽  
Early Use

Four cases of pneumonitis associated with the inhalation of mercury vapor are described in detail. Three of the four cases were fatal. The illness was characterized by the sudden onset of tachypnea, cough, fever, gastrointestinal disturbances and central nervous system manifestations. Ordinary laboratory tests were not helpful in establishing the diagnosis. Quantitative analysis of the urine for mercury was suggestive but not diagnostic. Roentgenograms of the lungs revealed interstitial pneumonitis. Analysis of tissue for mercury in the lungs, liver and spleen of two of the cases showed substantially increased mercury content. The outstanding pathologic features in the three fatal cases were erosive bronchitis and bronchiolitis, with severe interstitial pneumonitis. The presently accepted mode of therapy for acute poisoning due to ingestion of mercury is early use of BAL. Its use is probably also indicated in acute poisoning due to inhalation of mercury vapor. Supportive care in the form of oxygen, mist, and parenteral fluids is indicated.

Should All Children With a Positive Blood Culture Have a Lumbar Puncture?

PEDIATRICS ◽  
1975 ◽  
Vol 55 (2) ◽  
pp. 300-300
Author(s):  
John Vogel
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Blood Culture ◽  
Lumbar Puncture ◽  
Positive Blood Culture ◽  
Clinical Condition ◽  
Diagnostic Approach

Dr. Rapkin's article1 makes an important contribution to the diagnostic approach to children with acute infectious illnesses. The findings of meningitis on repeat lumbar puncture point out the need for continued vigilance even after an initially negative LP. However, his suggestion that "a positive blood culture mandates a repeat LP" can perhaps be modified by a review of the child's clinical condition at the time a positive blood culture is reported. Patients 1 through 4 in his report all displayed central nervous system abnormalities—convulsions, lethargy, apnea—before the blood culture was reported as positive.

scholarly journals Aggressive pituitary lesion with a remarkably high Ki-67

2014 ◽  
Vol 58 (6) ◽  
pp. 656-660 ◽  
Author(s):  
Pedro Marques ◽  
Manuela Mafra ◽  
Carlos Calado ◽  
Anabela Martins ◽  
Joaquim Monteiro ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Severe Disease ◽  
Laboratory Data ◽  
Pituitary Tumors ◽  
Sudden Onset ◽  
World Health ◽  
Treatment Modalities ◽  
Pituitary Neoplasms ◽  
Ki 67

The uncommon aggressive pituitary tumors are named carcinomas when metastases are detected, either in the central nervous system and/or systemically. Some cases are associated with hormonal overproduction, but most are diagnosed because of local symptoms. These neoplasias are generally refractory to current treatments. A 51 year-old woman presented sudden onset of headache, left arm paresis and left facial hypoesthesia. Computed tomography scan and magnetic resonance imaging revealed a pituitary tumor invading the left sphenoidal and cavernous sinuses. Laboratory data excluded hormonal hypersecretion. The patient underwent transsphenoidal surgery and histological findings showed a neoplasia with Ki-67 estimated at 75%. Medical imaging excluded both a primary occult tumor and central nervous system or systemic dissemination. Three weeks postoperatively, neurological condition worsened, with new onset of ataxia, bilateral ptosis, ophthalmoplegia and an increase in the size of the lesion, leading to surgical intervention by craniotomy, followed by only a few sessions of radiotherapy, because of severe disease progression. Patient died nearly 2 months after the initial manifestations. This case illustrates the aggressiveness of some pituitary lesions, the limited efficacy of current treatment modalities such as surgery or radiotherapy and the pitfalls of the current pituitary tumors classification. To our knowledge, this case corresponds to one of the most aggressive pituitary neoplasms reported so far, with a very high Ki-67 index (75%) and short survival (2 months). Ki-67 index could be of prognostic value in pituitary tumors. Pituitary tumors World Health Organization (WHO) classification could be revisited.

Extramedullary Spinal Cord Tumors

2018 ◽  
Author(s):  
J. Bradley Elder ◽  
Ahmed Mohyeldin
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Specific Area ◽  
Spinal Cord Tumors ◽  
Central Nervous System Neoplasms ◽  
Case Presentation ◽  
Presenting Symptoms ◽  
Spine Tumors ◽  
Nervous System Neoplasms

Tumors of the spine that occur within the dura but outside of the spinal cord are characterized as intradural but extramedullary spine tumors. The vast majority of these tumors are benign. This chapter uses a case presentation to present diagnostic and management pearls for this anatomic category of central nervous system neoplasms. These tumors are typically diagnosed due to presenting symptoms including pain or neurologic symptoms that localize the tumor to a specific area of the spine. Management is typically surgical. Some types of tumors are associated with syndromes such as neurofibromatosis. This chapter also discusses potential pitfalls and complications and their management.

scholarly journals A Rare Case of Cysticercosis Involving the Whole Spinal Canal

2021 ◽  
Author(s):  
Xiaoyan Zheng ◽  
Fei Wang ◽  
Lei Wang ◽  
Xiaoli Li ◽  
Jingjing Li ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Central Nervous System ◽  
Nervous System ◽  
Spinal Canal ◽  
Rare Case ◽  
Parasitic Disease ◽  
Epidemiological Investigation ◽  
Case Presentation ◽  
Life Threatening ◽  
The Central Nervous System

Abstract Background Cysticercosis is the commonest parasitic disease to affect the central nervous system (CNS). However, cysticercosis affecting the spine is extremely rare. We reported a rare case of cysticercosis involving the whole spinal canal in China. Case Presentation A rare case of cysticercosis involving the entire spinal cord, in a 52-year-old Chinese man, was detected in 2021. Epidemiological investigation, clinical and etiological examination was performed. Conclusion Since spinal cysticercosis is a rare but potentially life-threatening disease, clinicians should always consider the differential diagnosis of space-occupying lesions.

scholarly journals A case report: venous sinus thrombosis in pregnancy

2017 ◽  
Vol 6 (10) ◽  
pp. 4721
Author(s):  
Abhilasha Singh ◽  
Smiti Nanda
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Presentation ◽  
Sinus Thrombosis ◽  
Sudden Onset ◽  
Venous Sinus ◽  
Radiological Investigation ◽  
Venous Sinus Thrombosis ◽  
Central Nervous System Disorders ◽  
In Pregnancy

Venous sinus thrombosis (VST) should be considered in the differential diagnosis of all unexplained central nervous system disorders of sudden onset. Etiological factors are subclinical forms of several common thrombophilic states occurring together, rather than the typical inherited and rare causes. Diagnosis is often missed because of the heterogeneity in clinical presentation and radiological investigation is essential for the diagnosis. Prognosis depends on the early detection. By correcting the cause, the complications can be prevented.

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