Characteristics and clinical significance of spondylolisthetic and spino-pelvic sagittal parameters in kyphotic low-grade degenerative lumbar spondylolisthesis

Sagittal Parameters ◽

Abstract Background: Degenerative lumbar spondylolisthesis (DLS) has been a common disease that make increasing patients suffer from different degrees of low back pain and radicular symptoms. At present, the incidence of kyphosis in DLS and the differences in spinal sagittal morphology between kyphotic and non-kyphotic DLS still remain unclear. Our study aimed to determine the incidence of kyphosis in DLS, explore the characteristics of spondylolisthetic and spino-pelvic sagittal parameters, and evaluate the impact of kyphosis on the life quality of patients with DLS.Methods/Design: All 108 patients with L4/5 low-grade DLS were enrolled and divided into kyphotic and non-kyphotic group. 2 spine surgeons who have certain clinical experience were selected to measure the spondylolisthetic and spino-pelvic parameters, as well as visual analogue scale (VAS) and Oswestry disability index (ODI). Differences between the 2 groups and characteristics of measurements were analyzed.Results: The inter-observer agreement of all parameters between the 2 spine surgeons were excellent with each ICC > 0.75. Kyphotic group had higher SA, SD, SDM, SAM, PDH, PT and SVA, and lower ADH, SS and LL than those in non-kyphotic group (p < 0.01). There was no significant difference in PI and TK between the two groups (p > 0.05).Conclusion: The incidence of kyphotic spondylolisthesis in patients with L4/5 low-grade DLS is 16.7%. Compared with those in non-kyphotic group, patients with kyphosis show inferior results of spondylolisthetic parameters, more severe loss of LL, more obvious pelvic retroversion and trunk anteversion, which indicates worse spino-pelvic sagittal balance. In addition, their quality of life was significantly lower than that of patients in non-kyphotic group.

Characteristics and Clinical Significance of Spondylolisthetic and Spino-pelvic Sagittal Parameters in Kyphotic Low-grade Degenerative Lumbar Spondylolisthesis

10.21203/rs.3.rs-80642/v1 ◽

2020 ◽

Author(s):

Chongqing Xu ◽

Mengchen Yin ◽

Wen Mo

Keyword(s):

Life Quality ◽

Observer Agreement ◽

Common Disease ◽

Low Grade ◽

Significant Difference ◽

Sagittal Parameters ◽

Global sagittal spinal alignment in patients with degenerative low-grade lumbar spondylolisthesis

Journal of Orthopaedic Surgery ◽

10.1177/2309499019885190 ◽

2019 ◽

Vol 27 (3) ◽

pp. 230949901988519

Author(s):

Hiroto Kobayashi ◽

Kenji Endo ◽

Yasunobu Sawaji ◽

Yuji Matsuoka ◽

Hirosuke Nishimura ◽

...

Keyword(s):

Sacral Slope ◽

Low Grade ◽

Spinal Alignment ◽

Sagittal Spinal Alignment ◽

Significant Difference ◽

Type 3

Purpose: Global sagittal spinal alignment undergoes changes on the basis of sagittal malalignment (trunk inclined forward) in natural degenerative progression. We hypothesized that this change would associate with the disease state of the degenerative lumbar spondylolisthesis (DS). This study aimed to evaluate the global sagittal spinal alignment of low-grade DS by classifying in accordance with sagittal vertical axis (SVA). Methods: The DS group was classified into three types according to the adult spinal deformity classification: type 1, SVA < 40 mm; type 2, 40 mm ≤ SVA < 95 mm; and type 3, 95 mm ≤ SVA. Age and sagittal spinal parameters (thoracic kyphosis, lumbar lordosis (LL), sacral slope (SS), pelvic tilt (PT), and pelvic incidence (PI)) were compared among three types. Results: There were statistically significant differences in age, LL, PI, and PT among the three types. In comparison between two types, there was a statistically significant difference between type 1 and type 2 and between type 1 and type 3, but not between type 2 and type 3 in these parameters. PI tended to increase as the type increases. Furthermore, there was significant difference between types 1 and 3. Conclusion: We evaluated the features of the DS types classified by sagittal alignment. Large PI is one of the risk factors for SVA deterioration of DS. PI may be involved in the onset and progression of DS.

Impact of Poverty on Quality of Education in Haiti

Journal of Education ◽

10.53819/810181025019 ◽

2021 ◽

Vol 4 (7) ◽

pp. 1-9

Author(s):

Dube Moffatt Gedro ◽

Keyword(s):

Gender Equity ◽

Life Quality ◽

Quality Education ◽

Government Support ◽

School Age Children ◽

Quality Of Education ◽

Significant Difference ◽

The Government ◽

Education is among the critical needs besides the food, shelter and clothing in modern life. Quality education is an effective tool for minimizing poverty and joblessness, enhancing health and dietary standards, and attaining lasting growth. Hence, the study sought to determine the impact of poverty on the quality of education in Haiti. The study was a literature review based. The conclusions were based on reviewing previous studies. The study findings indicated that poverty influences the quality of education. The study noted the significance of education in developing countries could not be overstated. Quality education can be the catalyst needed to pull families and communities out of the cycle of poverty. Knowledge gives children the power to dream of a better future and the confidence required to pursue a complete education, which will help generations to come. The study further ascertained that education makes a significant difference for adults, particularly in day-to-day life, including nutrition, healthcare and gender equity. The poverty levels are potent in influencing the quality of education that the students will receive in the long run. The study recommended adequate mechanisms to ensure the government support children from a poor background. Addressing the academic difficulties children from deprived families will undoubtedly need a broader and bolder method to education policy than the current initiatives to reform schools. The government should make sure that school-age children are enrolled right into compulsory and free primary education. Given that education is a powerful device for minimizing poverty and joblessness, enhancing health and dietary requirements, and attaining sustainable advancement, the Haitian government must inject much more revenue in the education sector, mainly for the poor children to obtain a quality education. The government is required to make sure all learners within its nation have access to education both in rural and in metropolitan places. Keywords: Poverty, Quality of Education, Haiti

Laminectomy alone versus fusion for grade 1 lumbar spondylolisthesis in 426 patients from the prospective Quality Outcomes Database

Journal of Neurosurgery Spine ◽

10.3171/2018.8.spine17913 ◽

2019 ◽

Vol 30 (2) ◽

pp. 234-241 ◽

Cited By ~ 14

Author(s):

Andrew K. Chan ◽

Erica F. Bisson ◽

Mohamad Bydon ◽

Steven D. Glassman ◽

Kevin T. Foley ◽

...

Keyword(s):

Spine Surgery ◽

Leg Pain ◽

Readmission Rates ◽

Quality Outcomes ◽

Significant Difference ◽

Prospective Longitudinal

OBJECTIVEThe AANS launched the Quality Outcomes Database (QOD), a prospective longitudinal registry that includes demographic, clinical, and patient-reported outcome (PRO) data to measure the safety and quality of spine surgery. Registry data offer “real-world” insights into the utility of spinal fusion and decompression surgery for lumbar spondylolisthesis. Using the QOD, the authors compared the initial 12-month outcome data for patients undergoing fusion and those undergoing laminectomy alone for grade 1 degenerative lumbar spondylolisthesis.METHODSData from 12 top enrolling sites were analyzed and 426 patients undergoing elective single-level spine surgery for degenerative grade 1 lumbar spondylolisthesis were found. Baseline, 3-month, and 12-month follow-up data were collected and compared, including baseline clinical characteristics, readmission rates, reoperation rates, and PROs. The PROs included Oswestry Disability Index (ODI), back and leg pain numeric rating scale (NRS) scores, and EuroQol–5 Dimensions health survey (EQ-5D) results.RESULTSA total of 342 (80.3%) patients underwent fusion, with the remaining 84 (19.7%) undergoing decompression alone. The fusion cohort was younger (60.7 vs 69.9 years, p < 0.001), had a higher mean body mass index (31.0 vs 28.4, p < 0.001), and had a greater proportion of patients with back pain as a major component of their initial presentation (88.0% vs 60.7%, p < 0.001). There were no differences in 12-month reoperation rate (4.4% vs 6.0%, p = 0.93) and 3-month readmission rates (3.5% vs 1.2%, p = 0.45). At 12 months, both cohorts improved significantly with regard to ODI, NRS back and leg pain, and EQ-5D (p < 0.001, all comparisons). In adjusted analysis, fusion procedures were associated with superior 12-month ODI (β −4.79, 95% CI −9.28 to −0.31; p = 0.04).CONCLUSIONSSurgery for grade 1 lumbar spondylolisthesis—regardless of treatment strategy—was associated with significant improvements in disability, back and leg pain, and quality of life at 12 months. When adjusting for covariates, fusion surgery was associated with superior ODI at 12 months. Although fusion procedures were associated with a lower rate of reoperation, there was no statistically significant difference at 12 months. Further study must be undertaken to assess the durability of either surgical strategy in longer-term follow-up.

Quality of life in patients with vitiligo

International Journal of Research in Dermatology ◽

10.18203/issn.2455-4529.intjresdermatol20201586 ◽

2020 ◽

Vol 6 (3) ◽

pp. 388

Author(s):

Neela V. Bhuptani ◽

Pratik J. Parmar ◽

Nilam K. Selot ◽

Bharti K. Patel

Keyword(s):

Quality Of Life ◽

Dermatology Life Quality Index ◽

Life Quality ◽

Multidimensional Index ◽

Progressive Loss ◽

Significant Difference ◽

The Mean ◽

Moderate Effect ◽

Background: Vitiligo is an acquired disorder characterized by well circumscribed depigmented macules and patches that result from a progressive loss of functional melanocytes. In India and perhaps elsewhere also patients with vitiligo have severe psychological and social problems. Quality of life is multidimensional index of different social, behavioural and cultural factors. Different tools were developed for measuring quality of life focusing on different conditions and diseases. The dermatology life quality index (DLQI) questionnaire is designed for use in patients of age more than 16. It can be used to measure the impact of vitiligo on quality of life. To assess the dermatology specific quality of life in patients with vitiligo. To study impact of vitiligo on their quality of life.Methods: In this study 150 patients diagnosed with vitiligo during a 1-year period were included. DLQI was calculated for every patient. Results: The mean DLQI score in our study was 6.14. There was a statistically significant difference in mean DLQI of unmarried as compared to married. There were no statically significant differences in other groups. Out of 150 patients of vitiligo, 3 (2%) patients had no effect, 66 (44%) patients had small effect, 69 (46%) patients have moderate effect, while 12 (8%) patient had very large effect of vitiligo on their quality of life.Conclusions: Vitiligo affects quality of life in majority of patients. So, it should be treated aggressively with various treatment modality along with proper counselling and psychological support.

Does reduction of the Meyerding grade correlate with outcomes in patients undergoing decompression and fusion for grade I degenerative lumbar spondylolisthesis?

Journal of Neurosurgery Spine ◽

10.3171/2021.3.spine202059 ◽

2021 ◽

pp. 1-8

Author(s):

Andrew K. Chan ◽

Praveen V. Mummaneni ◽

John F. Burke ◽

Rory R. Mayer ◽

Erica F. Bisson ◽

...

Keyword(s):

Patient Reported Outcomes ◽

Rating Scale ◽

Lumbar Fusion ◽

Radiographic Appearance ◽

Lumbar Decompression ◽

Significant Difference ◽

Patient Reported ◽

OBJECTIVE Reduction of Meyerding grade is often performed during fusion for spondylolisthesis. Although radiographic appearance may improve, correlation with patient-reported outcomes (PROs) is rarely reported. In this study, the authors’ aim was to assess the impact of spondylolisthesis reduction on 24-month PRO measures after decompression and fusion surgery for Meyerding grade I degenerative lumbar spondylolisthesis. METHODS The Quality Outcomes Database (QOD) was queried for patients undergoing posterior lumbar fusion for spondylolisthesis with a minimum 24-month follow-up, and quantitative correlation between Meyerding slippage reduction and PROs was performed. Baseline and 24-month PROs, including the Oswestry Disability Index (ODI), EQ-5D, Numeric Rating Scale (NRS)–back pain (NRS-BP), NRS-leg pain (NRS-LP), and satisfaction (North American Spine Society patient satisfaction questionnaire) scores were noted. Multivariable regression models were fitted for 24-month PROs and complications after adjusting for an array of preoperative and surgical variables. Data were analyzed for magnitude of slippage reduction and correlated with PROs. Patients were divided into two groups: < 3 mm reduction and ≥ 3 mm reduction. RESULTS Of 608 patients from 12 participating sites, 206 patients with complete data were identified in the QOD and included in this study. Baseline patient demographics, comorbidities, and clinical characteristics were similarly distributed between the cohorts except for depression, listhesis magnitude, and the proportion with dynamic listhesis (which were accounted for in the multivariable analysis). One hundred four (50.5%) patients underwent lumbar decompression and fusion with slippage reduction ≥ 3 mm (mean 5.19, range 3 to 11), and 102 (49.5%) patients underwent lumbar decompression and fusion with slippage reduction < 3 mm (mean 0.41, range 2 to −2). Patients in both groups (slippage reduction ≥ 3 mm, and slippage reduction < 3 mm) reported significant improvement in all primary patient reported outcomes (all p < 0.001). There was no significant difference with regard to the PROs between patients with or without intraoperative reduction of listhesis on univariate and multivariable analyses (ODI, EQ-5D, NRS-BP, NRS-LP, or satisfaction). There was no significant difference in complications between cohorts. CONCLUSIONS Significant improvement was found in terms of all PROs in patients undergoing decompression and fusion for lumbar spondylolisthesis. There was no correlation with clinical outcomes and magnitude of Meyerding slippage reduction.

Income and Life Quality of Farmer Households Suffering Social Exclusion

Journal of Economics and Development ◽

10.33301/2012.14.03.04 ◽

2012 ◽

pp. 63-87

Author(s):

Anh Mai Ngoc ◽

Ha Do Thi Hai ◽

Huyen Nguyen Thi Ngoc

Keyword(s):

Labor Market ◽

Statistical Method ◽

Social Exclusion ◽

Central Government ◽

Life Quality ◽

Economic Aspect ◽

Local Authorities ◽

This study uses descriptive statistical method to analyze the income and life qual- ity of 397 farmer households who are suffering social exclusion in an economic aspect out of a total of 725 households surveyed in five Northern provinces of Vietnam in 2010. The farmers’ opinions of the impact of the policies currently prac- ticed by the central government and local authorities to give them access to the labor market are also analyzed in this study to help management officers see how the poli- cies affect the beneficiaries so that they can later make appropriate adjustments.

Antecedents And Outcomes Of Qwl Among Employees In Banks

Restaurant Business ◽

10.26643/rb.v118i7.7241 ◽

2019 ◽

Vol 118 (7) ◽

pp. 1-19

Author(s):

Geethanjali N ◽

Parveen Roja M ◽

Lavanya D

Keyword(s):

Organizational Climate ◽

Job Stress ◽

Work Life ◽

Working Environment ◽

Quality Of Work Life ◽

Quality Of Work ◽

Significant Difference ◽

Service Productivity ◽

Quality of work life is the major factor to be considered in working environment of any organization. The performance of employees and the organization lies on the ability of the employees based on working environment. The QWL leads to better working environment which improves the performance of organization. The present study has made an attempt to find the level of factors causing QWL and the impact of outcome of QWL in banks. Since the profile of the banks may be associated with the level of outcomes of QWL, the present study has made an attempt to examine it with the help of one way analysis of variance and t-test. The included outcomes of QWL are job satisfaction, job stress, organizational climate, organizational commitment, employees retention behaviour, service quality employees and service productivity of employees. The highly associated determinants of QWL and the significant difference among the PUSBs and PRSBs have been noticed. The significantly associating important profiles of the banks regarding the existence of outcome of QWL are identified.

Оrganic Meat Production of Broiler Chickens Hubbard Redbro Cross

International Journal of Veterinary Science ◽

10.37422/ijvs/20.072 ◽

2020 ◽

Keyword(s):

Broiler Chickens ◽

Raw Materials ◽

Animal Health ◽

Meat Products ◽

Poultry Meat ◽

Meat Production ◽

Significant Difference ◽

Environmentally Safe ◽

This article presents the results of studying the impact of housing and feeding conditions on broiler chickens of Hubbard RedBro cross, as well as the quality of products obtained when using floor and cage content, in a farm. It established that when receiving a mixed feed of own production using feed raw materials grown on a farm without the use of pesticides, a statistically significant decrease in potentially dangerous substances for animal health is recorded. Compared with factory feed, it has reduced the content of pesticides by 14 times, and mercury and arsenic by 24 times, cadmium by five times, and lead by ten times. The results of the study of economic indicators of growing Hubbard RedBro cross broiler chickens, as well as the chemical composition and quality of carcasses, indicated that there was no significant difference between the floor and cell conditions of keeping. Still, the use of a diet based on eco-feeds contributed to a statistically significant decrease in the concentration of toxic metals in the muscles of the poultry of the experimental groups. As a result, it found that the use of the studied compound feed in the diets of broiler chickens increased the indicators of Biosafety and ensured the production of environmentally safe ("organic") poultry meat products.

QOL-36. USE OF CANNABINOIDS IN THE PEDIATRIC CENTRAL NERVOUS SYSTEM TUMOR POPULATION

Neuro-Oncology ◽

10.1093/neuonc/noaa222.695 ◽

2020 ◽

Vol 22 (Supplement_3) ◽

pp. iii438-iii438

Author(s):

Kathleen Dorris ◽

Jessica Channell ◽

Ashley Mettetal ◽

Molly Hemenway ◽

Natalie Briones ◽

...

Keyword(s):

Quality Of Life ◽

Central Nervous System ◽

Nervous System ◽

Cell Activity ◽

Cns Tumors ◽

Low Grade ◽

Tumor Type ◽

Central Nervous System Tumor ◽

Abstract BACKGROUND Cannabinoids, including cannabidiol (CBD) and tetrahydrocannabinol (THC), are a class of compounds found in marijuana. Numerous studies in adults have examined cannabinoid use in management of cancer-related symptoms such as nausea, anorexia, and pain. Less is known about the use in the pediatric oncology population. METHODS A prospective observational study has been ongoing since 2016 at Children’s Hospital Colorado to evaluate cannabinoids’ impact using PedsQL™ modules on quality of life of pediatric patients with central nervous system (CNS) tumors who are 2–18 years old. Laboratory assessments of T-cell activity and pharmacokinetics of CBD, THC and associated metabolites are in process. Diaries with exploratory information on cannabinoid use patterns are being collected. RESULTS Thirty-three patients (14:19; male:female) have been enrolled with a median age of 6.4 years (range, 2.9–17.7 years). The most common tumor type in enrolled patients is embryonal tumors (13/33; 39%). Nine (27%) patients have low-grade glial/glioneuronal tumors, and eight (24%) had high-grade/diffuse midline gliomas. The remaining patients had ependymoma or craniopharyngioma. The median time on cannabinoids is 9 months. Most (n=20) patients have used oral products with CBD and THC. One patient continues on cannabinoid therapy in follow up. Preliminary immune function analyses identified impaired neutrophil superoxide anion production and chemotaxis in patients taking cannabinoids at early time points on therapy. CONCLUSIONS Families of children with various CNS tumors are pursuing cannabinoid therapy for both antitumor and supportive care purposes. Analysis of the impact of cannabinoids on patients’ quality of life is ongoing.