scholarly journals The hip radiographic magnification correlates with patient’s BMI

Author(s):  
Jana Hornová ◽  
Maroš Hrubina ◽  
Eduard Šťastný ◽  
Andrea Košková ◽  
Petr Fulín ◽  
...  

Abstract Objective. Obese patients have a higher prevalence of total hip arthroplasty (THA) and they are likely to experience a higher rate of pre-operative and post-operative complications. Pre-operative templating is a standard method of THA planning aiming to minimize the risk of complications. The accuracy of pre-operative templating depends on the knowledge of radiographic magnification factor. Whether and to what extent obesity affects radiographic magnification is not well described in literature. The purpose of this study was to determine whether obesity type affects hip radiographic magnification and quantify the relationship between the obesity measured and change in radiographic magnification. Materials and Methods. Digital radiographs of 303 patients who underwent THA were taken from clinical archives. The size of implanted femoral head was taken as an internal calibration marker to estimate hip radiographic magnification. Patients were stratified into obesity categories by body mass index (BMI). Patients’ mass, BMI, and body surface area (BSA) were studied as predictors of hip magnification. Results. There is a significant effect of obesity type on hip radiographic magnification (one-way ANOVA, p<0.001). The radiographic magnification correlates with patients’ mass (r=0.443, p<0.001), BMI (r=0.450, p<0.001) and BSA (r=0.443, p<0.001). For every 17 kg increase in patients’ mass, 5 kg/m2 increase in the BMI and for every 0.27 m2 in the BSA there is a 1 percent increase in the hip radiographic magnification. The increase in hip radiographic magnification with mass, BMI, and BSA is higher in females than in males. Conclusion. BMI could be used to estimate the increase in hip radiographic magnification due to obesity by adding 1% of magnification on average for each subsequent BMI category.

2018 ◽  
Vol 12 (01) ◽  
pp. 120-122
Author(s):  
Basma Ezzat Mustafa Al-Ahmad ◽  
Muhannad Ali Kashmoola ◽  
Nazih Shaaban Mustafa ◽  
Haszelini Hassan ◽  
Mohd Hafiz Arzmi

ABSTRACTObjective: This study aimed to investigate the relationship between tooth loss and the level of blood pressure with the hypothesis that tooth loss is associated with the increase of hypertension in postmenopausal women. Materials and Methods: Sixty postmenopausal female patients aged 51-68 years were included in the study to assess the relationship between tooth loss and the level of blood pressure. The information including sociodemographics, last menstruation period, hypertension history, and the duration of having tooth loss was recorded. Blood pressure was measured using sphygmomanometer and the number of tooth loss was determined. Results: The results showed a more significant tooth loss in hypertension (median: 23 + 4; interquartile range [IQR]: 6) compared to the normotension postmenopausal women (median: 18 + 6; IQR: 12; P < 0.05). Furthermore, obese patients had more tooth loss (median: 23 + 5; IQR: 8) than the overweight patients (median: 19 + 8; IQR: 8). Conclusion: Tooth loss is associated with the increase of hypertension in postmenopausal women which may have a role in the development of vascular diseases.


1993 ◽  
Vol 21 (3) ◽  
pp. 309-310 ◽  
Author(s):  
R. W. Watts

This study confirms that distance to the epidural space from the skin at the L3–4 interspace is only moderately correlated with body mass index in obstetric patients. A similar moderate linear correlation was found in the non-obstetric patients. However, in obese patients (BMI>25), distance to epidural space from the skin correlated poorly with body mass index.


2019 ◽  
Vol 65 (9) ◽  
pp. 1115-1124 ◽  
Author(s):  
Lynley K Lewis ◽  
Sara D Raudsepp ◽  
Timothy C R Prickett ◽  
Timothy G Yandle ◽  
Robert N Doughty ◽  
...  

Abstract BACKGROUND Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Plasma concentrations of B-type natriuretic peptide (BNP) or its amino terminal congener (NT-proBNP) are used for HF diagnosis and risk stratification. Because BNP concentrations are inexplicably lowered in obese patients, we investigated the relationship between proBNP glycosylation, plasma NT-proBNP, and body mass index (BMI) in HF patients. METHODS Three assays were developed to distinguish between total proBNP (glycosylated plus nonglycosylated proBNP), proBNP not glycosylated at threonine 71 (NG-T71), and proBNP not glycosylated in the central region (NG-C). Intraassay and interassay CVs were &lt;15%; limits of detection were &lt;21 ng/L; and samples diluted in parallel. RESULT Applying these assays and an NT-proBNP assay to plasma samples from 106 healthy volunteers and 238 HF patients determined that concentrations [median (interquartile range)] of proBNP, NG-T71, and NT-proBNP were greater in HF patients compared with controls [300 (44–664), 114 (18–254), and 179 (880–3459) ng/L vs 36 (18–229), 36 (18–175), and 40 (17–68) ng/L, respectively; all P &lt; 0.012]. NG-C was undetectable in most samples. ProBNP concentrations in HF patients with BMI more or less than 30 kg/m2 were not different (P = 0.85), whereas HF patients with BMI &gt;30 kg/m2 had lower NT-proBNP and NG-T71 concentrations (P &lt; 0.003) and higher proBNP/NT-proBNP and proBNP/NG-T71 ratios (P = 0.001 and P = 0.02, respectively) than those with BMI &lt;30 kg/m2. CONCLUSIONS Increased BMI is associated with decreased concentrations of proBNP not glycosylated at T71. Decreased proBNP substrate amenable to processing could partially explain the lower NT-proBNP and BNP concentrations observed in obese individuals, including those presenting with HF.


Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Olutoyosi Ogunkua ◽  
Abu Minhajuddin ◽  
Jason Pai ◽  
Girish Joshi ◽  
Charles Whitten ◽  
...  

Background: Higher transthoracic impedance may influence the success of defibrillation. We evaluated the relationship between body mass index (BMI) and post-defibrillation outcomes for in-hospital ventricular fibrillation or pulseless ventricular tachycardia (VF/VT). Methods: Within the Get With The Guidelines - Resuscitation multicenter observational registry, we identified adult patients who received biphasic waveform defibrillation for in-hospital VT/VF cardiac arrest between 2008 and2012. We evaluated the relationship between BMI and defibrillation outcomes using a generalized linear mixed regression to adjust for patient arrest characteristics and comorbidities while accounting for within hospital clustering. The primary outcome was successful termination of VF/VT. Secondary outcomes included termination of VF/VT to an organized rhythm with pulse, return of spontaneous circulation ≥ 20 minutes (ROSC), survival at 24 hours, and survival to discharge. Results: A total of 10,561 adult subjects with VF/VT from 268 hospitals were analyzed. BMI was not associated with termination of VT/VF following defibrillation. However, compared to normal BMI patients, underweight and morbidly obese patients were less likely to have termination of VT/VF with restoration of a pulse. Further, underweight patients were less likely to survive to 24 hours and discharge. In contrast, overweight and obese patients were more likely to survive to 24 hours and discharge (see Table). Summary: Successful termination of VF/VT was not associated with BMI. However, a non-linear relationship exists between BMI and termination of VF/VT to an organized rhythm with pulse, ROSC, survival at 24 h and survival at discharge.


2013 ◽  
Vol 18 (2) ◽  
pp. 17e1-17e7 ◽  
Author(s):  
José Rino Neto ◽  
João Batista de Paiva ◽  
Gilberto Vilanova Queiroz ◽  
Miguel Ferragut Attizzani ◽  
Hiroshi Miasiro Junior

OBJECTIVE: The purpose of this study was to evaluate the influence of the magnification factor of the radiographic image in angular, linear and proportional measurements. METHODS: From a dried human skull where metallic spheres with predetermined size were fixed (1.0 mm), 14 radiographs were obtained in devices of three different manufacturers: Panoura, Instrumentarium and Tomeceph. The Pearson correlation test was used to investigate the relationship between the rate of radiographic magnification and the cephalometric measurements assessed. RESULTS: According to the results, the linear measurements showed a high positive correlation, pointing out great influence of the magnification factor, while the angular and proportional measurements did not correlate. CONCLUSIONS: Comparisons between linear cephalometric measurements obtained with different devices from the same manufacturer showed maximum rates of expansion of 0.6%, 1.25% and 2.3%, respectively, for the devices from Instrumentarium (OP-100, Instrumentarium, Finland), Panoura (10CSU, Yoshida, Japan) and Satelec/Tomeceph (XMind, Satelec/Tomeceph Orion Corporation, Finland).


Biomedicines ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 1657
Author(s):  
Adela-Viviana Sitar-Tǎut ◽  
Angela Cozma ◽  
Adriana Fodor ◽  
Sorina-Cezara Coste ◽  
Olga Hilda Orasan ◽  
...  

Currently, adipose tissue is considered an endocrine organ, however, there are still many questions regarding the roles of adipokines—leptin and ghrelin being two adipokines. The purpose of the study was to assess the relationship between the adipokines and their ratio with obesity and diabetes. Methods: Sixty patients (mean age 61.88 ± 10.08) were evaluated. Cardiovascular risk factors, leptin, ghrelin, and insulin resistance score values were assessed. The patients were classified according to their body mass index (BMI) as normal weight, overweight, and obese. Results: 20% normal weight, 51.7% overweight, 28.3% obese, and 23.3% diabetic. Obese patients had higher leptin values (in obese 34,360 pg/mL vs. overweight 18,000 pg/mL vs. normal weight 14,350 pg/mL, p = 0.0049) and leptin/ghrelin ratio (1055 ± 641 vs. 771.36 ± 921 vs. 370.7 ± 257, p = 0.0228). Stratifying the analyses according to the presence of obesity and patients’ gender, differences were found for leptin (p = 0.0020 in women, p = 0.0055 in men) and leptin/ghrelin ratio (p = 0.048 in women, p = 0.004 in men). Mean leptin/BMI and leptin/ghrelin/BMI ratios were significantly higher, and the ghrelin/BMI ratio was significantly lower in obese and diabetic patients. In conclusion, obesity and diabetes are associated with changes not only in the total amount but also in the level of adipokines/kg/m2. Changes appear even in overweight subjects, offering a basis for early intervention in diabetic and obese patients.


2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Manuel B. Huber ◽  
Christoph Kurz ◽  
Florian Kirsch ◽  
Larissa Schwarzkopf ◽  
Anja Schramm ◽  
...  

Abstract Background Body mass index (BMI) is an important parameter associated with mortality and health-related quality of life (HRQoL) in chronic obstructive pulmonary disease (COPD). However, informed guidance on stratified weight recommendations for COPD is still lacking. This study aims to determine the association between BMI and HRQoL across different severity grades of COPD to support patient management. Methods We use conjunct analysis of claims and survey data based on a German COPD disease management program from 2016 to 2017. The EQ-5D-5L visual analog scale (VAS) and COPD Assessment Test (CAT) are used to measure generic and disease-specific HRQoL. Generalized additive models with smooth functions are implemented to evaluate the relationship between BMI and HRQoL, stratified by COPD severity. Results 11,577 patients were included in this study. Mean age was 69.4 years and 59% of patients were male. In GOLD grades 1–3, patients with BMI of around 25 had the best generic and disease-specific HRQoL, whereas in GOLD grade 4, obese patients had the best HRQoL using both instruments when controlled for several variables including smoking status, income, COPD severity, comorbidities, emphysema, corticosteroid use, and days spent in hospital. Conclusion This real-world analysis shows the non-linear relationship between BMI and HRQoL in COPD. HRQoL of obese patients with mild to severe COPD might improve following weight reduction. For very severe COPD, a negative association of obesity and HRQoL could not be confirmed. The results hint at the need to stratify COPD patients by disease stage for optimal BMI management.


1994 ◽  
Vol 72 (01) ◽  
pp. 058-064 ◽  
Author(s):  
Goya Wannamethee ◽  
A Gerald Shaper

SummaryThe relationship between haematocrit and cardiovascular risk factors, particularly blood pressure and blood lipids, has been examined in detail in a large prospective study of 7735 middle-aged men drawn from general practices in 24 British towns. The analyses are restricted to the 5494 men free of any evidence of ischaemic heart disease at screening.Smoking, body mass index, physical activity, alcohol intake and lung function (FEV1) were factors strongly associated with haematocrit levels independent of each other. Age showed a significant but small independent association with haematocrit. Non-manual workers had slightly higher haematocrit levels than manual workers; this difference increased considerably and became significant after adjustment for the other risk factors. Diabetics showed significantly lower levels of haematocrit than non-diabetics. In the univariate analysis, haematocrit was significantly associated with total serum protein (r = 0*18), cholesterol (r = 0.16), triglyceride (r = 0.15), diastolic blood pressure (r = 0.17) and heart rate (r = 0.14); all at p <0.0001. A weaker but significant association was seen with systolic blood pressure (r = 0.09, p <0.001). These relationships remained significant even after adjustment for age, smoking, body mass index, physical activity, alcohol intake, lung function, presence of diabetes, social class and for each of the other biological variables; the relationship with systolic blood pressure was considerably weakened. No association was seen with blood glucose and HDL-cholesterol. This study has shown significant associations between several lifestyle characteristics and the haematocrit and supports the findings of a significant relationship between the haematocrit and blood lipids and blood pressure. It emphasises the role of the haematocrit in assessing the risk of ischaemic heart disease and stroke in individuals, and the need to take haematocrit levels into account in determining the importance of other cardiovascular risk factors.


1970 ◽  
Vol 25 (1) ◽  
pp. 9-13
Author(s):  
S Jahan ◽  
TR Das ◽  
KB Biswas

Background and Aims: Cord blood leptin may reflect the leptinemic status of a newborn at birth more accurately than the leptin values of blood collected from other sites. The present study was undertaken to determine the relationship of cord serum leptin concentration at birth with neonatal and maternal anthropometric parameters. Materials and Methods: Blood was taken from the umbilical cord of the babies at delivery. Maternal anthropometric measurements were recorded at admission for delivery. Neonatal anthropometric measurements were recorded within 48 hours after delivery. Linear regression analysis was used to explore the relationship between cord serum leptin concentration and anthropometric parameters of the baby and the mother. Both Serum leptin and serum C-peptide levels were measured by chemiluminescence-based ELISA method. Results: The leptin concentration (ng/ml, mean±SD) in cord blood was 39.13±14.44. Cord leptin levels correlated with birth weight (r=0.673, p<0.0001), ponderal index (r=0.732, p<0.0001) but it did not correlate with maternal body mass index, gestational age (r=0.135, p=0.349) at delivery or cord serum C-peptide concentration (r=-0.049, p=0.735) or placental weight (r=0.203, p=0.157). Conclusion: There are associations between cord leptin concentration at delivery and birth weight, ponderal index (PI) of the babies but not body mass index (BMI) of the mothers. High leptin levels of the baby could represent an important feedback modulator of substrate supply and subsequently for adipose tissue status during late gestation. (J Bangladesh Coll Phys Surg 2007; 25 : 9-13)


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