scholarly journals Training a Machine Learning Classifier to Identify ADHD Based on Real-World Clinical Data From Medical Records

2022 ◽  
Author(s):  
Pavol Mikolas ◽  
Amirali Vahid ◽  
Fabio Bernardoni ◽  
Mathilde Süß ◽  
Julia Martini ◽  
...  
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Clinical Data ◽  
Medical Records ◽  
Real Life ◽  
Diagnostic Process ◽  
Support Vector ◽  
Svm Classifier ◽  
Psychiatric Conditions ◽  
Clinical Records

Abstract The diagnostic process of attention deficit hyperactivity disorder (ADHD) is complex and relies on criteria sensitive to subjective biases. This may cause significant delays in appropriate treatment initiation. An automated analysis relying on subjective and objective measures might not only simplify the diagnostic process and reduce the time to diagnosis, but also improve reproducibility. While recent machine learning studies have succeeded at distinguishing ADHD from healthy controls, the clinical process requires differentiating among other or multiple psychiatric conditions. We trained a linear support vector machine (SVM) classifier to detect participants with ADHD in a population showing a broad spectrum of psychiatric conditions using anonymized data from clinical records (N = 299 participants). We differentiated children and adolescents with ADHD from those not having the condition with an accuracy of 66.1 %. SVM using single features showed slight differences between single features and overlapping standard deviations of the achieved accuracies. An automated feature selection achieved the best performance using a combination 19 features. Real-life clinical data from medical records can be used to automatically identify individuals with ADHD among help-seeking individuals using machine learning. The relevant diagnostic information can be reduced using an automated feature selection without loss of performance. A broad combination of symptoms across different domains, rather than specific domains, seems to indicate an ADHD diagnosis.

Classification of Crop Residue Cover in High-Resolution RGB Images Using Machine Learning

2022 ◽  
Vol 65 (1) ◽  
pp. 75-86
Author(s):  
Parth C. Upadhyay ◽  
John A. Lory ◽  
Guilherme N. DeSouza ◽  
Timotius A. P. Lagaunne ◽  
Christine M. Spinka
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Feature Selection Method ◽  
Texture Features ◽  
Ground Truth ◽  
Selection Method ◽  
Support Vector ◽  
Svm Classifier ◽  
Aerial Vehicle ◽  
Rgb Images

HighlightsA machine learning framework estimated residue cover in RGB images taken at three resolutions from 88 locations.The best results primarily used texture features, the RFE-SVM feature selection method, and the SVM classifier.Accounting for shadows and plants plus modifying and optimizing the texture features may improve performance.An automated system developed using machine learning is a viable strategy to estimate residue cover from RGB images obtained with handheld or UAV platforms.Abstract. Maintaining plant residue on the soil surface contributes to sustainable cultivation of arable land. Applying machine learning methods to RGB images of residue could overcome the subjectivity of manual methods. The objectives of this study were to use supervised machine learning while identifying the best feature selection method, the best classifier, and the most effective image feature types for classifying residue levels in RGB imagery. Imagery was collected from 88 locations in 40 row-crop fields in five Missouri counties between early May and late June in 2018 and 2019 using a tripod-mounted camera (0.014 cm pixel-1 ground sampling distance, GSD) and an unmanned aerial vehicle (UAV, 0.05 and 0.14 GSD). At each field location, 50 contiguous 0.3 × 0.2 m region of interest (ROI) images were extracted from the imagery, resulting in a dataset of 4,400 ROI images at each GSD. Residue percentages for ground truth were estimated using a bullseye grid method (n = 100 points) based on the 0.014 GSD images. Representative color, texture, and shape features were extracted and evaluated using four feature selection methods and two classifiers. Recursive feature elimination using support vector machine (RFE-SVM) was the best feature selection method, and the SVM classifier performed best for classifying the amount of residue as a three-class problem. The best features for this application were associated with texture, with local binary pattern (LBP) features being the most prevalent for all three GSDs. Shape features were irrelevant. The three residue classes were correctly identified with 88%, 84%, and 81% 10-fold cross-validation scores for the 2018 training data and 81%, 69%, and 65% accuracy for the 2019 testing data in decreasing resolution order. Converting image-wise data (0.014 GSD) to location residue estimates using a Bayesian model showed good agreement with the location-based ground truth (r2 = 0.90). This initial assessment documents the use of RGB images to match other methods of estimating residue, with potential to replace or be used as a quality control for line-transect assessments. Keywords: Feature selection, Soil erosion, Support vector machine, Texture features, Unmanned aerial vehicle.

scholarly journals Sentiment Analysis for Social Media using SVM Classifier of Machine Learning

2019 ◽  
Vol 8 (9S4) ◽  
pp. 39-47
Keyword(s):  
Machine Learning ◽  
Social Media ◽  
Feature Selection ◽  
Sentiment Analysis ◽  
Language Processing ◽  
Cuckoo Search ◽  
Support Vector ◽  
Svm Classifier ◽  
Feature Selection Technique ◽  
Performance Factors

Sentiment analysis is an area of natural language processing (NLP) and machine learning where the text is to be categorized into predefined classes i.e. positive and negative. As the field of internet and social media, both are increasing day by day, the product of these two nowadays is having many more feedbacks from the customer than before. Text generated through social media, blogs, post, review on any product, etc. has become the bested suited cases for consumer sentiment, providing a best-suited idea for that particular product. Features are an important source for the classification task as more the features are optimized, the more accurate are results. Therefore, this research paper proposes a hybrid feature selection which is a combination of Particle swarm optimization (PSO) and cuckoo search. Due to the subjective nature of social media reviews, hybrid feature selection technique outperforms the traditional technique. The performance factors like f-measure, recall, precision, and accuracy tested on twitter dataset using Support Vector Machine (SVM) classifier and compared with convolution neural network. Experimental results of this paper on the basis of different parameters show that the proposed work outperforms the existing work

scholarly journals Classification of radiology reports for falls in an HIV study cohort

2015 ◽  
Vol 23 (e1) ◽  
pp. e113-e117 ◽  
Author(s):  
Jonathan Bates ◽  
Samah J Fodeh ◽  
Cynthia A Brandt ◽  
Julie A Womack
Keyword(s):  
Machine Learning ◽  
Feature Selection ◽  
Electronic Health Record ◽  
Supervised Machine Learning ◽  
Support Vector ◽  
Svm Classifier ◽  
Study Cohort ◽  
Health Record ◽  
Radiology Reports ◽  
Electronic Health

Abstract Objective To identify patients in a human immunodeficiency virus (HIV) study cohort who have fallen by applying supervised machine learning methods to radiology reports of the cohort. Methods We used the Veterans Aging Cohort Study Virtual Cohort (VACS-VC), an electronic health record-based cohort of 146 530 veterans for whom radiology reports were available ( N =2 977 739). We created a reference standard of radiology reports, represented each report by a feature set of words and Unified Medical Language System concepts, and then developed several support vector machine (SVM) classifiers for falls. We compared mutual information (MI) ranking and embedded feature selection approaches. The SVM classifier with MI feature selection was chosen to classify all radiology reports in VACS-VC. Results Our SVM classifier with MI feature selection achieved an area under the curve score of 97.04 on the test set. When applied to all the radiology reports in VACS-VC, 80 416 of these reports were classified as positive for a fall. Of these, 11 484 were associated with a fall-related external cause of injury code (E-code) and 68 932 were not, corresponding to 29 280 patients with potential fall-related injuries who could not have been found using E-codes. Discussion Feature selection was crucial to improving the classifier’s performance. Feature selection with MI allowed us to select the number of discriminative features to use for classification, in contrast to the embedded feature selection method, in which the number of features is chosen automatically. Conclusion Machine learning is an effective method of identifying patients who have suffered a fall. The development of this classifier supplements the clinical researcher’s toolkit and reduces dependence on under-coded structured electronic health record data.

Binary Spectrum Feature for Improved Classifier Performance

2020 ◽  
Author(s):  
Nalika Ulapane ◽  
Karthick Thiyagarajan ◽  
sarath kodagoda
Keyword(s):  
Machine Learning ◽  
Classification Performance ◽  
Feature Reduction ◽  
Sensor Data ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Svm Classifier ◽  
Monitoring Task ◽  
Classifier Performance ◽  
Spectrum Feature

<div>Classification has become a vital task in modern machine learning and Artificial Intelligence applications, including smart sensing. Numerous machine learning techniques are available to perform classification. Similarly, numerous practices, such as feature selection (i.e., selection of a subset of descriptor variables that optimally describe the output), are available to improve classifier performance. In this paper, we consider the case of a given supervised learning classification task that has to be performed making use of continuous-valued features. It is assumed that an optimal subset of features has already been selected. Therefore, no further feature reduction, or feature addition, is to be carried out. Then, we attempt to improve the classification performance by passing the given feature set through a transformation that produces a new feature set which we have named the “Binary Spectrum”. Via a case study example done on some Pulsed Eddy Current sensor data captured from an infrastructure monitoring task, we demonstrate how the classification accuracy of a Support Vector Machine (SVM) classifier increases through the use of this Binary Spectrum feature, indicating the feature transformation’s potential for broader usage.</div><div><br></div>

Identification of Chronic Hypersensitivity Pneumonitis Biomarkers with Machine Learning and Differential Co-expression Analysis

2020 ◽  
Vol 20 ◽  
Author(s):  
Hongwei Zhang ◽  
Steven Wang ◽  
Tao Huang
Keyword(s):  
Feature Selection ◽  
Expression Analysis ◽  
Hypersensitivity Pneumonitis ◽  
Enrichment Analysis ◽  
Functional Enrichment ◽  
Great Promise ◽  
Support Vector ◽  
Svm Classifier ◽  
Clinical Tool ◽  
Chronic Hypersensitivity Pneumonitis

Aims: We would like to identify the biomarkers for chronic hypersensitivity pneumonitis (CHP) and facilitate the precise gene therapy of CHP. Background: Chronic hypersensitivity pneumonitis (CHP) is an interstitial lung disease caused by hypersensitive reactions to inhaled antigens. Clinically, the tasks of differentiating between CHP and other interstitial lungs diseases, especially idiopathic pulmonary fibrosis (IPF), were challenging. Objective: In this study, we analyzed the public available gene expression profile of 82 CHP patients, 103 IPF patients, and 103 control samples to identify the CHP biomarkers. Method: The CHP biomarkers were selected with advanced feature selection methods: Monte Carlo Feature Selection (MCFS) and Incremental Feature Selection (IFS). A Support Vector Machine (SVM) classifier was built. Then, we analyzed these CHP biomarkers through functional enrichment analysis and differential co-expression analysis. Result: There were 674 identified CHP biomarkers. The co-expression network of these biomarkers in CHP included more negative regulations and the network structure of CHP was quite different from the network of IPF and control. Conclusion: The SVM classifier may serve as an important clinical tool to address the challenging task of differentiating between CHP and IPF. Many of the biomarker genes on the differential co-expression network showed great promise in revealing the underlying mechanisms of CHP.

A fuzzy gaussian rank aggregation ensemble feature selection method for microarray data

2021 ◽  
Vol 24 (4) ◽  
pp. 289-301
Author(s):  
B. Venkatesh ◽  
J. Anuradha
Keyword(s):  
Feature Selection ◽  
Microarray Data ◽  
Classification Accuracy ◽  
Performance Metrics ◽  
Feature Selection Method ◽  
Selection Method ◽  
Support Vector ◽  
Svm Classifier ◽  
Binary Particle Swarm Optimization ◽  
Selection Methods

In Microarray Data, it is complicated to achieve more classification accuracy due to the presence of high dimensions, irrelevant and noisy data. And also It had more gene expression data and fewer samples. To increase the classification accuracy and the processing speed of the model, an optimal number of features need to extract, this can be achieved by applying the feature selection method. In this paper, we propose a hybrid ensemble feature selection method. The proposed method has two phases, filter and wrapper phase in filter phase ensemble technique is used for aggregating the feature ranks of the Relief, minimum redundancy Maximum Relevance (mRMR), and Feature Correlation (FC) filter feature selection methods. This paper uses the Fuzzy Gaussian membership function ordering for aggregating the ranks. In wrapper phase, Improved Binary Particle Swarm Optimization (IBPSO) is used for selecting the optimal features, and the RBF Kernel-based Support Vector Machine (SVM) classifier is used as an evaluator. The performance of the proposed model are compared with state of art feature selection methods using five benchmark datasets. For evaluation various performance metrics such as Accuracy, Recall, Precision, and F1-Score are used. Furthermore, the experimental results show that the performance of the proposed method outperforms the other feature selection methods.

scholarly journals A Comparison of Feature Selection and Forecasting Machine Learning Algorithms for Predicting Glycaemia in Type 1 Diabetes Mellitus

2021 ◽  
Vol 11 (4) ◽  
pp. 1742
Author(s):  
Ignacio Rodríguez-Rodríguez ◽  
José-Víctor Rodríguez ◽  
Wai Lok Woo ◽  
Bo Wei ◽  
Domingo-Javier Pardo-Quiles
Keyword(s):  
Diabetes Mellitus ◽  
Machine Learning ◽  
Type 1 Diabetes ◽  
Feature Selection ◽  
Blood Glucose ◽  
Type 1 Diabetes Mellitus ◽  
Support Vector ◽  
Chronic Hyperglycemia ◽  
Predictive Algorithms

Type 1 diabetes mellitus (DM1) is a metabolic disease derived from falls in pancreatic insulin production resulting in chronic hyperglycemia. DM1 subjects usually have to undertake a number of assessments of blood glucose levels every day, employing capillary glucometers for the monitoring of blood glucose dynamics. In recent years, advances in technology have allowed for the creation of revolutionary biosensors and continuous glucose monitoring (CGM) techniques. This has enabled the monitoring of a subject’s blood glucose level in real time. On the other hand, few attempts have been made to apply machine learning techniques to predicting glycaemia levels, but dealing with a database containing such a high level of variables is problematic. In this sense, to the best of the authors’ knowledge, the issues of proper feature selection (FS)—the stage before applying predictive algorithms—have not been subject to in-depth discussion and comparison in past research when it comes to forecasting glycaemia. Therefore, in order to assess how a proper FS stage could improve the accuracy of the glycaemia forecasted, this work has developed six FS techniques alongside four predictive algorithms, applying them to a full dataset of biomedical features related to glycaemia. These were harvested through a wide-ranging passive monitoring process involving 25 patients with DM1 in practical real-life scenarios. From the obtained results, we affirm that Random Forest (RF) as both predictive algorithm and FS strategy offers the best average performance (Root Median Square Error, RMSE = 18.54 mg/dL) throughout the 12 considered predictive horizons (up to 60 min in steps of 5 min), showing Support Vector Machines (SVM) to have the best accuracy as a forecasting algorithm when considering, in turn, the average of the six FS techniques applied (RMSE = 20.58 mg/dL).

scholarly journals Value of radiomics in differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma

2019 ◽  
Vol 45 (10) ◽  
pp. 3193-3201 ◽  
Author(s):  
Yajuan Li ◽  
Xialing Huang ◽  
Yuwei Xia ◽  
Liling Long
Keyword(s):  
Machine Learning ◽  
Differential Diagnosis ◽  
Cell Carcinoma ◽  
Area Under The Curve ◽  
Image Features ◽  
Renal Tumors ◽  
Support Vector ◽  
Svm Classifier ◽  
Renal Oncocytoma ◽  
Lasso Regression

Abstract Purpose To explore the value of CT-enhanced quantitative features combined with machine learning for differential diagnosis of renal chromophobe cell carcinoma (chRCC) and renal oncocytoma (RO). Methods Sixty-one cases of renal tumors (chRCC = 44; RO = 17) that were pathologically confirmed at our hospital between 2008 and 2018 were retrospectively analyzed. All patients had undergone preoperative enhanced CT scans including the corticomedullary (CMP), nephrographic (NP), and excretory phases (EP) of contrast enhancement. Volumes of interest (VOIs), including lesions on the images, were manually delineated using the RadCloud platform. A LASSO regression algorithm was used to screen the image features extracted from all VOIs. Five machine learning classifications were trained to distinguish chRCC from RO by using a fivefold cross-validation strategy. The performance of the classifier was mainly evaluated by areas under the receiver operating characteristic (ROC) curve and accuracy. Results In total, 1029 features were extracted from CMP, NP, and EP. The LASSO regression algorithm was used to screen out the four, four, and six best features, respectively, and eight features were selected when CMP and NP were combined. All five classifiers had good diagnostic performance, with area under the curve (AUC) values greater than 0.850, and support vector machine (SVM) classifier showed a diagnostic accuracy of 0.945 (AUC 0.964 ± 0.054; sensitivity 0.999; specificity 0.800), showing the best performance. Conclusions Accurate preoperative differential diagnosis of chRCC and RO can be facilitated by a combination of CT-enhanced quantitative features and machine learning.

Feature Selection Method Based on Mutual Information and Support Vector Machine

2021 ◽  
pp. 2150021
Author(s):  
Gang Liu ◽  
Chunlei Yang ◽  
Sen Liu ◽  
Chunbao Xiao ◽  
Bin Song
Keyword(s):  
Support Vector Machine ◽  
Feature Selection ◽  
Mutual Information ◽  
Classification Accuracy ◽  
Feature Selection Method ◽  
Selection Method ◽  
Support Vector ◽  
Svm Classifier ◽  
Standard Data ◽  
Feature Dimension

A feature selection method based on mutual information and support vector machine (SVM) is proposed in order to eliminate redundant feature and improve classification accuracy. First, local correlation between features and overall correlation is calculated by mutual information. The correlation reflects the information inclusion relationship between features, so the features are evaluated and redundant features are eliminated with analyzing the correlation. Subsequently, the concept of mean impact value (MIV) is defined and the influence degree of input variables on output variables for SVM network based on MIV is calculated. The importance weights of the features described with MIV are sorted by descending order. Finally, the SVM classifier is used to implement feature selection according to the classification accuracy of feature combination which takes MIV order of feature as a reference. The simulation experiments are carried out with three standard data sets of UCI, and the results show that this method can not only effectively reduce the feature dimension and high classification accuracy, but also ensure good robustness.

Classification of Diffusion Tensor Metrics for the Diagnosis of a Myelopathic Cord Using Machine Learning

2018 ◽  
Vol 28 (02) ◽  
pp. 1750036 ◽  
Author(s):  
Shuqiang Wang ◽  
Yong Hu ◽  
Yanyan Shen ◽  
Hanxiong Li
Keyword(s):  
Machine Learning ◽  
Surgical Planning ◽  
Diffusion Tensor ◽  
Mean Value ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Svm Classifier ◽  
Control Groups ◽  
Diffusion Tensor Imaging Dti

In this study, we propose an automated framework that combines diffusion tensor imaging (DTI) metrics with machine learning algorithms to accurately classify control groups and groups with cervical spondylotic myelopathy (CSM) in the spinal cord. The comparison between selected voxel-based classification and mean value-based classification were performed. A support vector machine (SVM) classifier using a selected voxel-based dataset produced an accuracy of 95.73%, sensitivity of 93.41% and specificity of 98.64%. The efficacy of each index of diffusion for classification was also evaluated. Using the proposed approach, myelopathic areas in CSM are detected to provide an accurate reference to assist spine surgeons in surgical planning in complicated cases.

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