scholarly journals Dietary Daidzein Supplementation Improved Growth Performance and Antioxidant Properties in Weaned and Growing Pigs

2021 ◽  
Author(s):  
Yanpin Li ◽  
Xianren Jiang ◽  
Long Cai ◽  
Yanli Zhang ◽  
Hongbiao Ding ◽  
...  
Keyword(s):  
Cell Viability ◽  
Growth Performance ◽  
Soybean Meal ◽  
Average Daily Gain ◽  
Antioxidant Properties ◽  
Dietary Supplementation ◽  
Growing Pigs ◽  
Related Factor ◽  
Mda Content

Abstract Background: In previous study, we found that soybean isoflavones in soybean meal play important roles in improving growth performance and antioxidant properties in pigs. However, it is still not known whether long-term supplementation with daidzein, an active molecule deglycosylated from daidzin, in a corn-soybean meal diet can enhance growth performance in pigs. Thus, in the present study, an animal trial was carried out to investigate the effects of dietary supplementation with daidzein on the growth performance and antioxidant capacity of pigs. Porcine intestinal epithelial cells (IPEC-J2) were also used as an in vitro model to explore the underlying antioxidant mechanisms of daidzein. Weanling pigs were fed a diet supplemented with 0, 25, 50, and 100 mg/kg daidzein, and IPEC-J2 cells were treated with 0.6 mM hydrogen peroxide (H2O2) in the presence or absence of 40 μM daidzein. Results: Adding 50 mg/kg daidzein to the diet significantly improved body weight on day 72, average daily gain during days 0-72 and plasma superoxide dismutase activity on day 42 (P < 0.05). Treatment with 0.6 mM H2O2 for 1 h significantly decreased cell viability and catalase (CAT) activities and increased intracellular reactive oxygen species (ROS) levels and malondialdehyde (MDA) content (P < 0.05), while pretreatment with 40 μM daidzein prevented the decrease in cell viability and CAT activities and the increase in intracellular ROS levels and MDA content caused by H2O2 (P < 0.05). In addition, H2O2 stimulation significantly suppressed the expression of nuclear factor erythoid-2-related factor 2 (Nrf2), CAT, occludin and zonula occludens-1 (ZO-1), while pretreatment with daidzein preserved the expression of Nrf2, CAT, occludin and ZO-1 in H2O2-stimulated IPEC-J2 cells (P < 0.05).Conclusions: Long-term dietary supplementation with 50 mg/kg daidzein improved growth performance and antioxidative properties in pigs. Daidzein exerted protective effects against H2O2-induced oxidative stress in IPEC-J2 cells, and the underlying mechanism may be related to the activation of the Kelch-like ECH-associated protein 1-Nrf2/antioxidant response element signaling pathway.

Effects of Quillaja saponin supplementation on growth performance, nutrient digestibility, fecal microbiota, and fecal gas emission in growing pigs

2021 ◽  
Author(s):  
De Xin Dang ◽  
In Ho Kim
Keyword(s):  
Growth Performance ◽  
Control Diet ◽  
Average Daily Gain ◽  
Dietary Supplementation ◽  
Fecal Microbiota ◽  
Nutrient Digestibility ◽  
Growing Pigs ◽  
Coliform Bacteria ◽  
Gas Emission ◽  
Quillaja Saponin

The purpose of this study was to evaluate the effects of dietary supplementation of Quillaja saponin (QS) on growth performance, nutrient digestibility, fecal microbiota, and fecal gas emission in growing pigs. A total of 50 crossbred growing pigs [(Yorkshire × Landrace) × Duroc] with an initial body weight of 23.83 ± 1.95 kg were randomly assigned to 1 of 2 treatments for a 56-day trial with 5 replicate pens per treatment and 5 pigs (2 barrows and 3 gilts) per pen. Dietary treatments including control diet and control diet supplemented with 200 mg/kg QS. The average daily gain was significantly increased during days 0-56, while the fecal ammonia emission on day 56 and fecal coliform bacteria counts on day 28 were significantly decreased in pigs fed with QS containing diet. However, dietary supplementation of QS had no significant effects on apparent total tract digestibility. In conclusion, dietary supplementation of 200 mg/kg QS had beneficial effects on growth performance, fecal microbiota, and fecal gas emission in growing pigs. Considering the carry-over effects, the adaption period should be at least 28 days when supplementing 200 mg/kg QS to the diet of growing pigs for improving the growth performance.

Dietary supplementation of ferulic acid improves performance and alleviates oxidative stress of lambs in a cold environment

2019 ◽  
Vol 99 (4) ◽  
pp. 705-712 ◽  
Author(s):  
Yuan Wang ◽  
Wenwen Wang ◽  
Ruifang Wang ◽  
Ziqi Meng ◽  
Yuanxiao Duan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Ferulic Acid ◽  
Growth Performance ◽  
Average Daily Gain ◽  
Dietary Supplementation ◽  
Neutral Detergent Fiber ◽  
Cold Environment ◽  
Plasma Glutathione Peroxidase ◽  
Mda Content ◽  
Dietary Treatments

Ferulic acid (FA) has been regarded as an antioxidant in domestic animals’ feed. This study was to investigate whether dietary FA supplementation could improve growth performance by decreasing oxidative stress of lambs in cold environment. Thirty-two 3-mo-old crossbred male lambs (Dorper × Small-tail Han sheep; 30.49 ± 0.46 kg) were randomly assigned into one of the following dietary treatments: CON (control, no FA), FA80 (80 mg FA kg−1of diet), FA400 (400 mg FA kg−1of diet), and FA2000 (2000 mg FA kg−1of diet). Lambs fed the FA80 had higher (P < 0.05) average daily gain and lower (P < 0.05) feed efficiency than those fed CON and FA2000. The dry matter, organic matter, and neutral detergent fiber apparent digestibility was lower (P < 0.05) for FA2000 lambs than for lambs from other treatments. Serum total protein and albumin concentrations were greater (P < 0.05) for FA80 group than other groups. Lambs fed FA80 had higher (P < 0.05) plasma glutathione peroxidase and catalase activities and lower (P < 0.05) malondialdehyde (MDA) content than lambs fed CON. However, FA2000 group showed higher (P < 0.05) plasma MDA content than CON group. In conclusion, dietary supplementation of 80 mg FA kg−1diet could improve growth performance by decreasing oxidative stress of lambs in cold environment.

scholarly journals Effects of dietary inclusion of GuarPro F-71 on the growth performance and nutrient metabolism in young growing pigs

2020 ◽  
Vol 8 (3) ◽  
pp. 143-149
Author(s):  
M.S. Hasan ◽  
R.M. Humphrey ◽  
Z. Yang ◽  
M.A. Crenshaw ◽  
J. Brett ◽  
...  
Keyword(s):  
Growth Performance ◽  
Soybean Meal ◽  
Feed Intake ◽  
Feed Efficiency ◽  
Average Daily Gain ◽  
Plasma Concentrations ◽  
Clinical Signs ◽  
Growing Pigs ◽  
Future Research ◽  
Nutrient Metabolism

Using alternative feedstuffs can be a feasible measure to reduce swine production cost. GuarPro F-71 (GP71), a newly developed guar meal product, is considered as a potential protein source for pigs. This preliminary study was conducted to evaluate the effects of GP71 inclusion in feed on growth performance and nutrient metabolism of growing pigs. Sixty crossbred barrows (31.9±1.84 kg body weight (BW)) were allotted to one of five dietary treatments in a completely randomised experiment design, with four pens/treatment and three pigs/pen. Diet 1 was a maize- and soybean-based basal control diet formulated to meet NRC recommendations. GP71 was used to replace 25, 50, 75, and 100% soybean meal in diet 1 (on an equivalent crude protein (CP) basis) to generate diets 2, 3, 4, and 5, respectively. Crystalline amino acids were used to balance the essential amino acid concentrations across the five diets. Inclusion of GP71 quadratically reduced average daily feed intake (ADFI) (P=0.01) with no observed clinical signs of unhealthiness of pigs. The blood plasma concentrations of six metabolites, including urea nitrogen, total protein, albumin, glucose, total cholesterol and total triglycerides, were not affected (P>0.30), indicating that the pigs’ metabolic utilisation of nutrients was not compromised. The cubic effect (P<0.05) of dietary GP71 inclusion on G:F ratio suggested that the level of soybean meal replacement (up to 75% soybean meal) did not negatively affect feed efficiency in pigs. In short, the feed intake reduction due to the dietary GP71 inclusion was, if not solely, responsible for the average daily gain (ADG) and final BW reduction. This study suggested that using GP71 to replace soybean meal up to 75% (on an equivalent CP basis) can negatively affect ADFI and ADG, but not feed efficiency, in growing pigs. The reasons for the ADFI and ADG reduction need to be understood in future research.

scholarly journals PSVI-2 Dietary supplementation of Bacillus licheniformis derived-protease increased the digestibility of dry matter and crude protein in post-weaned and growing pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 199-200
Author(s):  
Woo Jung Seok ◽  
Lei Cheng ◽  
Thanapal Palanisamy ◽  
Xiangting Fu ◽  
In Ho Kim
Keyword(s):  
Growth Performance ◽  
Bacillus Licheniformis ◽  
Crude Protein ◽  
Dry Matter ◽  
Average Daily Gain ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Growing Pigs ◽  
Feed Ratio ◽  
Phase 3

Abstract This study aimed to evaluate the effects of supplemental Bacillus licheniformis derived-protease in diets on growth performance, apparent total tract digestibility (ATTD), and fecal microbial shedding in post-weaned growing pigs. In total, 90 crossbred (Landrace × Yorkshire × Duroc) weaner pigs with an initial average BW of 6.61 ± 1.73 kg were randomly allotted into 2 treatments with 9 replicate pens of 5 pigs for a 4-phase feeding trial (0 to 1, 1 to 3, 3 to 6, and 6 to 11 weeks). The treatments were: CON, corn-soybean meal based basal diet; PROT, basal diet + 0.05% protease. The basal diet contained 16.32, 15.91, 15.49, and 14.91 MJ/kg digestibility energy respectively and 1.50, 1.40, 1.30, and 1.00% lysine respectively for phase 1, 2, 3, and 4. All data were statistically analyzed by Student’s t-test of SAS 9.4 (SAS Institute Inc., Cary, NC, USA). Variability in the data was expressed as mean ± standard deviation, differences with P &lt; 0.05 were considered to be statistically significant. During phase 3, average daily gain, and gain: feed ratio was increased (P &lt; 0.05) in pigs fed PROT diet compared with those fed CON diet. Pigs fed PROT diet had higher (P &lt; 0.05) ATTD of dry matter and crude protein than pigs fed CON diet. No differences were observed in fecal microflora counts between CON and PROT groups. Dietary supplementation of Bacillus licheniformis derived-protease increased growth performance at phase 3 and increased the digestibility) of dry matter and crude protein (insert mean values for both Con vs Treat) in growing pigs.

64 Total Replacement of Inorganic Phosphorus by a Novel Consensus Bacterial 6-phytase Variant in Grower Pigs Fed Corn-soybean Meal-based Diets

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 43-44
Author(s):  
Deepak E Velayudhan ◽  
Marta Gracia ◽  
Leon Marchal ◽  
Yueming Dersjant-Li
Keyword(s):  
Growth Performance ◽  
Soybean Meal ◽  
Control Diet ◽  
Average Daily Gain ◽  
Inorganic Phosphorus ◽  
Positive Control ◽  
Growing Pigs ◽  
Net Energy ◽  
Feed Conversion ◽  
Percentage Points

Abstract The efficacy of a novel consensus bacterial 6-phytase variant (PhyG) to totally replace dietary inorganic phosphorus (Pi) was evaluated in grower pigs fed diets with reduced net energy (NE) and digestible amino acids (AA), using growth performance and total tract digestibility (ATTD) of nutrients as outcome measures. A total of 352 growing pigs (23.4 ± 1.3 kg) were randomized to 4 dietary treatments with 8 pigs/pen and 11 pens/treatment. Diets were corn, soybean meal, distiller’s dried grains with solubles and wheat middlings based, formulated by phase (Grower 1, 25 to 50 kg and Grower 2, 50 to 75 kg). The positive control (PC) diet provided adequate energy and nutrients. A negative control diet was formulated without Pi (0.12% STTD P) and reduced Ca (-0.12 to -0.13 percentage points), NE (-32 kcal/kg) and essential AA (-0.15 to 0.3 percentage points) vs. PC. The NC was supplemented with 500 or 1,000 FTU/kg of PhyG. Data were analyzed by analysis of variance and orthogonal polynomial were used for linear response to increasing PhyG. Nutrient reductions in the NC reduced (P &lt; 0.05) average daily gain (ADG) during both phases and overall, increased (P &lt; 0.05) feed conversion ratio (FCR) and tended to reduce (P &lt; 0.1) feed intake during Grower 1 and overall, vs. PC. Supplementation of PhyG showed linear improvement (P &lt; 0.05) in FCR during Grower 1 and ADG during Grower 2 and PhyG at 1,000 FTU/kg maintained a similar growth performance compared to PC. Addition of PhyG improved (P &lt; 0.001) ATTD P and tended to improve ATTD of DE (P &lt; 0.1) in linear manner. In conclusion, the novel consensus phytase can replace Pi and compensate for the reduction of Ca, NE and digestible AA in grower pig diets with equal performance compared to the nutrients adequate positive control.

scholarly journals Dietary replacement of fish meal by defatted and fermented soybean meals with taurine supplementation for pompano fish: effects on growth performance, nutrient digestibility, and biological parameters in a long-term feeding period

2020 ◽  
Vol 98 (12) ◽  
Author(s):  
Hung Phuc Nguyen ◽  
Thinh Van Do ◽  
Hau Duc Tran
Keyword(s):  
Growth Performance ◽  
Soybean Meal ◽  
Fish Meal ◽  
Basal Diet ◽  
Nutrient Digestibility ◽  
Biological Parameters ◽  
Feeding Period ◽  
Taurine Supplementation ◽  
Fermented Soybean

Abstract A 16-wk growth trial was conducted to examine the effects of dietary replacement of fish meal by defatted soybean meal (SBM) and fermented soybean meal (FSBM) with taurine supplementation on growth performance, nutrient apparent digestibility coefficient (ADC) and biological parameters of pompano fish. The FSBM was produced by fermenting SBM with Lactobacillus spp. Seven isonitrogenous and isoenergetic diets were formulated to replace 35% or 50% of fish meal by SBM or FSBM with taurine supplementation. The diets are denoted as follows: FM, SBM35, SBM35T, FSBM35T, SBM50, SBM50T, and FSBM50T. The FM (the basal diet) contained fish meal as a main source of dietary protein. Taurine was supplemented to SBM35T, FSBM35T, SBM50T, and FSBM50T at the level of 15 g/kg diet. Pompano juveniles with an initial body weight (BW) of 80 g reared in floating net cages were fed the experimental diets twice daily for 16 wk. Results showed that the final BW, weight gain, and feed conversion ratio of fish fed SBM35 and SBM50 were significantly lower than those of fish fed FM (P &lt; 0.05), indicating that the replacement of fish meal by SBM at the rate of 35% in the diet is excessive for pompano. Supplementation of taurine to the SBM-included diets significantly increased growth performance and feed utilization (P &lt; 0.05); however, these diets did not restore the performance back to a level equivalent to that of fish offered the basal diet. Meanwhile, fish fed FSBM35T had comparable growth and feed performances to those fed FM. Hematocrit values, total biliary bile acid levels, whole body lipid contents, and tissue taurine concentrations of fish fed SBM35 and SBM50 were the lowest among the treatments, but these parameters were improved by taurine supplementation and FSBM inclusion in the diet. Taurine supplementation increased lipid ADC, and SBM fermentation slightly enhanced both lipid and protein ADCs of the fish. These findings suggest that the combination of FSBM and taurine supplementation is an effective way to improve growth performance, nutrient digestibility, and biological parameters, and that FSBM with taurine supplementation can replace 35% of fish meal in pompano diets without any negative effects on growth and feed performances in a long-term feeding period.

scholarly journals 138 Effects of Increasing Soybean Meal in Corn-based Diets on Growth Performance of Late-finishing Pigs

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 70-71
Author(s):  
Julia P Holen ◽  
Robert D Goodband ◽  
Mike D Tokach ◽  
Jason C Woodworth ◽  
Joel M DeRouchey
Keyword(s):  
Amino Acids ◽  
Growth Performance ◽  
Soybean Meal ◽  
Fixed Effects ◽  
Average Length ◽  
Average Daily Gain ◽  
Random Effect ◽  
Finishing Pigs ◽  
Distillers Grains With Solubles ◽  
Dietary Treatments

Abstract Two experiments were conducted to determine the effects of increasing levels of soybean meal (SBM) replacing feed grade amino acids in corn or corn-dried distillers grains with solubles (DDGS)-based diets on growth performance of late finishing pigs. In both experiments, there were 22 to 27 pigs per pen and 14 pens per treatment. Average length of the experiments was 35 (Exp. 1) and 29 days (Exp. 2). Diets were balanced to contain 0.70% SID Lys and 2,667 or 2,610 kcal NE/kg for Exp. 1 and 2, respectively. Minimum amino acid ratios relative to Lys were: Ile, 55; Met&Cys, 60; Thr, 65; Trp, 19.5, and Val, 70. Dietary crude protein ranged from 10.1 to 15.2 for Exp. 1 and 13.6 to 19.4 for Exp. 2. The statistical model considered fixed effects of treatment, linear and quadratic contrasts, and random effect of block. In Exp.1, 1,793 pigs (L337×1050, PIC; initially 104.9 ± 1.4 kg) were fed corn-based diets and pens of pigs were assigned to 1 of 5 dietary treatments with increasing SBM from 5 to 20%. Overall, average daily gain (ADG) and gain-to-feed (G:F) increased (linear; P &lt; 0.05) as SBM increased with the greatest improvement observed as SBM increased from 5 to 8.75%, with little improvement thereafter. In Exp. 2, 1,827 pigs (L337×1050, PIC; initially 97.9 ± 1.1 kg) were used in a similar study as Exp. 1, but all diets contained 25% DDGS and SBM levels increased from 0 to 16%. Overall, G:F and final bodyweight of pigs marginally improved (linear and quadratic, respectively; P &lt; 0.10) as SBM increased, with the greatest performance observed when diets contained 8% SBM. These results suggest that increasing SBM up to 8% at the expense of feed grade amino acids in corn or corn-DDGS-based diets improved ADG or G:F in late-finishing pigs.

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