scholarly journals Local Steroid Treatment: An Effective Procedure for Idiopathic Granulomatous Mastitis, Including Complicated Cases

Author(s):  
Taha Furkan Ertürk ◽  
Özgür Çakır ◽  
Büşra Yaprak Bayrak ◽  
Abdullah Güneş ◽  
Selahattin Aydemir ◽  
...  

Abstract Purpose To evaluate the effectiveness of treatment with topical and intralesional steroids for idiopathic granulomatous mastitis (IGM) and to compare with surgical methods.Methods Data was retrospectively collected from records. Intralesional steroid injection and topical steroid administration, hereafter referred to as local steroid treatment (LST) were applied in Group 1. Surgery (local excision, wide excision and mastectomy) was performed in Group 2. In Group 1 changes in lesion sizes were recorded and factors complicating treatment were identified. The Numeric Pain Rating Scale was used to determine subjective pain. LST and surgery were compared with regard to: pain before and after the treatment; complication rate; recurrence rate; and treatment cost.Results There were 38 and 48 patients in Group 1 and Group 2, respectively. In the LST group 72 lesions were present and 70 of 72 (97%) responded completely to treatment. Pre-treatment median maximum diameter was 23.50 (15.25-35.25) mm, which regressed to 16 (12-25) mm after the first session. While the pre-treatment pain scores of Group 1 and Group 2 were similar (p=0.756), there was a significant difference in the post-treatment pain scores (p<0.001). No recurrence occurred in any patients in Group 1, while recurrence developed in 15 (31.2%) patients in Group 2 (p<0.001).Conclusion LST is a treatment for IGM that is cheap, with high efficiency, negligible recurrence, and has good esthetic outcome. Our results suggest that LST should be the first-line treatment option for all IGM patients, including complicated cases.

2021 ◽  
Author(s):  
Taha Furkan Ertürk ◽  
Özgür Çakır ◽  
Büşra Yaprak Bayrak ◽  
Abdullah Güneş ◽  
Selahattin Aydemir ◽  
...  

Abstract Background: This study aimed to evaluate the effectiveness of local steroid treatment (LST) for idiopathic granulomatous mastitis (IGM) and to compare with surgical methods.Methods: Data was retrospectively collected from hospital electronic records. The patients were divided into two groups, the LST group and the surgery group. Intralesional steroid injection and topical steroid administration were applied in LST group. Surgery and LST were compared with regard to: pain before and after the treatment; complication rate; recurrence rate; and treatment cost.Results: Seventy of 72 lesions responded completely to LST. Pre-treatment median maximum diameter was 23.50 (15.25-35.25) mm, which regressed to 16 (12-25) mm after the first LST session. LST was found to be superior to surgery in pain management. No recurrence occurred in any patients in LST group.Conclusion: LST is a treatment for IGM that is cheap, with high efficiency, negligible recurrence, and has good esthetic outcome.


2017 ◽  
Vol 22 (5) ◽  
pp. 75-82 ◽  
Author(s):  
Ezgi Atik ◽  
Tülin Taner

ABSTRACT Objective: The aim of this study was to compare the longitudinal stability of the conventional straight-wire system after the use of a quad-helix appliance with Damon self-ligating system in patients with Class I malocclusion. Methods: 27 adolescent patients were evaluated at three different periods: pre-treatment (T1), post-treatment (T2) and three years post-treatment (T3). Group 1 included 12 patients (with a mean age of 14.65 year) treated with Damon 3MX bracket system; and Group 2 included 15 patients (with a mean age of 14.8 year) who underwent orthodontic treatment with Roth prescribed brackets after expansion with Quad-Helix appliance. Relapse was evaluated with dental cast examination and cephalometric radiograph tracings. Statistical analysis was performed with IBM-SPSS for Windows software, version 21 (SPSS Inc., Chicago, IL). A p-value smaller than 0.05 was considered statistically significant. Results: There were significant increases in all transverse dental and postero-anterior measurements (except for UL6-ML mm in Group 1) with active treatment. There was some significant relapse in the long-term in inter-canine width in both groups and in the inter-first premolar width in Group 2 (p< 0.05). Significant decrease in all frontal measurements from T2 to T3 was seen for both groups. Upper and lower incisors significantly proclined in T1-T2 (p<0.05), however no relapse was found for both groups. When two systems were compared, there was no significant difference for the long-term follow-up period. Conclusion: Conventional (quad-helix appliance with conventional brackets) and Damon systems were found similar with regard to the long-term incisor positions and transverse dimension changes of maxillary arch.


2019 ◽  
pp. 12-19
Author(s):  
Shreya Bukkapatnam ◽  
Ms suma ◽  
Ravi Shankar Krishna ◽  
Baba Shankar Alva

Brief Background The purpose was to compare and evaluate border moulding using two different materials on mandibular edentulous arches. Materials and Methods This clinical study was performed on 15 healthy edentulous subjects who reported to the department of Prosthodontics. All the subjects were first given complete dentures, fabricated with low fusing compound as the border moulding material, followed by complete dentures with putty as the border moulding material. Retention was measured at 3 stages: Border moulding; Complete denture insertion; 6 weeks follow up. Patient’s satisfaction was measured with a 10 point visual analogue scale for both the dentures pre treatment and at the follow up visit. Results Putty border moulding showed higher retention as compared to low fusing compound border moulding with significant difference at all stages- stage 1 (p=0.011), stage 2 (p=0.009) and stage 3 (p=0.0054). The time taken for border moulding was significantly lower in Group 2 than Group 1(P=1.6E-48). According to VAS scores, in terms of aesthetic and comfort parameters, patients were satisfied in both groups without any significant difference, however, retention in Group 2 was higher as compared to group 1(P=0.05) Summary and Conclusions There was a statistically significant difference in the retention, between the groups. Group 2( Putty) had higher retention compared to Group 1(low fusing compound).Time taken for border moulding was significantly lower for Group 2( putty). No significant difference in patient’s satisfaction was observed for aesthetic and comfort parameters. In functional parameter, retention was better in Group 2(putty) subjects. Key Words: Low fusing compound, PVS (putty), border molding, mandibular edentulous arch.


Medicina ◽  
2013 ◽  
Vol 49 (8) ◽  
pp. 55
Author(s):  
Dalia Smailienė ◽  
Aistė Kavaliauskienė ◽  
Ingrida Pacauskienė

Background and Objective. There is considerable debate on the issues of the choice of a surgical technique for the treatment of palatally impacted maxillary canines. The aim of the study was to evaluate the posttreatment status of palatally impacted canines treated applying 2 different surgical methods, i.e., an open technique with free eruption and a closed flap technique, and to compare it with the status of naturally erupted canines. Material and Methods. In total, 43 patients treated for unilateral palatally impacted maxillary canines were examined at a mean follow-up of 4.19 months (SD, 1.44; range, 3–6) after a fixed appliance had been removed. The patients were distributed into 2 groups: the open technique with free eruption (group 1, n=22) and the closed technique (group 2, n=21). The posttreatment examination consisted of an intraoral and a radiological examination. Results. The findings of tooth position, inclination, color, shape, and function did not differ between the groups. There was no significant difference in the measurements of the periodontal pocket depth and bone support between the groups: the mean periodontal pocket depth was 2.14 mm (SD, 0.38) in the group 1 and 2.28 mm (SD, 0.69) in the group 2; the mean bone support was 91.51% (SD, 5.78%) and 89.9% (SD, 5%) in the groups, respectively. However, differences were found when comparing the measurements of the quadrant of impacted canines with the quadrant of the contralateral normally erupted canines. The distal contact point of the lateral incisor and the medial contact point of the canine showed a significant bone loss in comparison with the contralateral corresponding teeth. Conclusions. The posttreatment status of palatally impacted canines and adjacent teeth after the surgical-orthodontic treatment did not differ significantly between the groups of the open and the closed surgical method.


2021 ◽  
pp. 000348942110024
Author(s):  
Nevreste Didem Sonbay Yılmaz ◽  
Cansu Afyoncu ◽  
Nuray Ensari ◽  
Muhammet Yıldız ◽  
Özer Erdem Gür

Objectives: Vocal fold nodules (VFN) are a bilateral epithelial thickening of the membranous vocal folds. In this study, children with VFN and their mothers took part in voice therapy. We then compared acoustic analyzes and subjective evaluations to those in previous literature to determine whether voice therapy is more effective for children with VFN when their mothers also take part in therapy. Methods: Children aged eight to 12 years who were diagnosed with bilateral VFN between January 2018 and January 2020 were included in this study. Participating children diagnosed with bilateral VFN were divided into two groups based on the wishes and cooperation of their families. Group 1 consisted of 16 patients; Group 2 included 17 patients. The children in Group 1 received voice therapy alone; children in Group 2 took part in therapy with their mothers. For all participants, the average fundemental frequency (F0), jitter percentages, shimmer percentages, maximum phonation time (MPT) and s/z ratios were measured. Pediatric voice handicap index (p-VHI) values were calculated as well. Results: The two groups’ measures pre-treatment and post-treatment were compared. Except for p-VHI, no significant difference was observed between the two groups. However, p-VHI post-treatment was significantly lower in Group 2 than in Group 1. Conclusions: Involving the families and even teachers of children with VFN in voice therapy can increase the effectiveness of therapy. The family’s involvement increases the child’s motivation in therapy. The mother’s presence during therapy, supporting the child or even doing the work with the child, can be a very important source of motivation for the child, who may already be tired from school and other activities. Thus, the mother’s involvement increases the child’s compliance with and interest in therapy.


2021 ◽  
Vol 8 (8) ◽  
pp. 480-484
Author(s):  
Muzaffer Seyhan Cikman ◽  
Ismet Gun

Objective: In this study, we evaluated the effect of depression, anxiety, and stress on pain perception during colposcopy. Material and methods: This study was performed at the gynecologic oncology department of Lutfi Kirdar Kartal Education and Research Hospital in Istanbul, Turkey between September 2017 and January 2018. After taking informed consent, Depression Anxiety and Stress Scale (DASS-42) were completed by women who were attended outpatient colposcopy unit. Patients were classified into three groups according to DASS-42 (Group 1: patients without depression, anxiety or stress; Group 2: patients with one or two of depression, anxiety and stress; Group 3: patients with all of depression, anxiety and stress). Patient characteristics were also recorded. The degree of pain perception was evaluated visual analogue scale (VAS) at the end of the procedure. The p values less than 0.05 were considered statistically significant. Results: A total of 116 women were enrolled into this study. There was no statistically significant difference between the groups in terms of age, gravidity, parity, number of gynecologic examination, waiting time, BMI, VAS, having a partner, came alone to clinic, level of education, employment, indication of procedure, number of biopsies, ECC presence (p>0.05). There was no difference between the subgroups in terms of VAS. There was negative correlation between groups and VAS (r=-0.195, p=0.036). Conclusion: According to our findings, depression, anxiety and stress have no impact on pain perception during colposcopy but there is a weak correlation between the absence of depression, anxiety, stress and the pain score.


2018 ◽  
Vol 14 (4) ◽  
pp. 5020
Author(s):  
Hayriye Baltaoğlu Alp ◽  
Sevtap Darçın

Aim: The aim of this study was to compare ketamin(0.5mg/kg)-propofol(1mg/kg) and tramadol(1mg/kg)- propofol(1mg/kg) combination in patients undergoing uterine dilatation and curretage procedure  in terms of total propofol requirement, pain scoring and recovery period of duration .Methods: 100 women under going uterine dilatation and curettage were screened retrospectively after ethical comitee approval. Patients are Dr. Faruk Sükan Doğumevi, Konya, Turkey in January-July 2014 .   Baseline anesthesia was maintained with 1 mg/kg propofol, and the patients were randomly allocated to receive  0.5 mg/kg ketamine (Group 1, n=50) or 1 mg/kg tramadol (Group 2, n=50) there after.  Pain scores, Aldrete scores, and hemodynamic parameters were recorded during and after the surgical procedure. A record was also maintained of any adverse events.Results: When the Aldrete scores at the end of operation, systolic pressures at basal, 0,5,10 minutes,end of op., oxygen saturation at basal,0,5,10 minutes,end of op., diastolic blood pressure at basal,0,5,10 minutes,end of op., heart rates, and visual analogue scores were compared, there was no significant difference between groups (p>0.05) Postoperative heart rate and systolic arterial pressure on beginning were significantly higher in Group 1 compared with Group 2Conclusion: Tramadol might be a better alternative drug rather than ketamine due to better hemodynamic stability and lower respiratory depression rate were seen in patents with it.


2021 ◽  
Vol 12 (1) ◽  
pp. 6
Author(s):  
Zafar Ali Khan ◽  
Namdeo Prabhu ◽  
Naseer Ahmed ◽  
Abhishek Lal ◽  
Rakhi Issrani ◽  
...  

Dry socket is a common postoperative complication secondary to any tooth extraction but is more commonly associated with mandibular third molars. Dry socket has been treated with various treatment modalities with different success rates. This study aimed to evaluate the effect of using honey and zinc oxide eugenol as an intra-socket medicament for the treatment of dry sockets. Ninety patients were divided into three groups as follows: Group 1 “honey”: 30 patients; Group 2 “zinc oxide eugenol”: 30 patients; and Group 3 “control”: 30 patients. Pre-medication and post-medication pain scores at different time intervals were measured on a verbal rating scale. The mean ages of the patients in each of the groups were as follows: Group 1: 44.26 ± 14.14; Group 2: 45.30 ± 18.08; and Group 3: 51.93 ± 9.75. As regards verbal rating scale pain scores, a significant difference was noted in patients that belonged to Groups 1 and 2, with an immediate reduction in post-medication pain scores. However, patients belonging to Group 3 reported pain and discomfort for over a week. The use of honey and zinc oxide eugenol resulted in significant immediate post-medication pain scores in patients as compared to the control group. Therefore, both honey and zinc oxide eugenol can be used as treatment options for dry socket patients.


1993 ◽  
Vol 21 (2) ◽  
pp. 201-203 ◽  
Author(s):  
M. M. McSwiney ◽  
G. P. Joshi ◽  
P. Kenny ◽  
S. M. McCarroll

In a double-blind, randomised controlled trial, we studied 40 patients who received one of four intra-articular injections at the end of arthroscopic surgery. Each group contained ten patients. The patients in Group 1 received normal saline 25 ml; those in Group 2 received bupivacaine 0.25% 25 ml; those in Group 3 received morphine 5 mg in normal saline 25 ml; and those in Group 4 received a combination of bupivacaine 0.5% 12.5 ml and 5 mg of morphine made up to 25 ml with normal saline to produce the same bupivacaine concentration as Group 2. At the time the patient awoke, and 30min, Ihr, Ihr 30min, 2hr, 4hr, 8hr, 12hr, and 24hr postoperatively, pain was assessed using a visual analogue scale. The need for supplementary analgesic agents in the first 24 hours was recorded. All pain scores were significantly lower (P< 0.05) in Groups 2, 3 and 4 compared with the control group with the exception of Group 2 at 24 hours. Pain scores were significantly lower (P<0.05) for Group 2 compared with Group 3 for the first 90 minutes postoperatively. At 4, 8, 12 and 24 hours postoperatively the pain scores were significantly lower (P<0.05%) for Group 3 compared with Group 2. Group 4 had the lowest pain scores over the recorded period compared with the other groups. The need for supplemental analgesia was significantly lower (P<0.05) in the treatment Groups 2, 3 and 4 compared to the control Group 1. There was no significant difference in supplemental analgesic requirements between Groups 2, 3 and 4. A combination of bupivacaine and morphine injected intra-articularly following arthroscopy provided superior analgesia compared with that achieved by either drug alone.


VASA ◽  
2020 ◽  
Vol 49 (4) ◽  
pp. 281-284
Author(s):  
Atıf Yolgosteren ◽  
Gencehan Kumtepe ◽  
Melda Payaslioglu ◽  
Cuneyt Ozakin

Summary. Background: Prosthetic vascular graft infection (PVGI) is a complication with high mortality. Cyanoacrylate (CA) is an adhesive which has been used in a number of surgical procedures. In this in-vivo study, we aimed to evaluate the relationship between PVGI and CA. Materials and methods: Thirty-two rats were equally divided into four groups. Pouch was formed on back of rats until deep fascia. In group 1, vascular graft with polyethyleneterephthalate (PET) was placed into pouch. In group 2, MRSA strain with a density of 1 ml 0.5 MacFarland was injected into pouch. In group 3, 1 cm 2 vascular graft with PET piece was placed into pouch and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. In group 4, 1 cm 2 vascular graft with PET piece impregnated with N-butyl cyanoacrylate-based adhesive was placed and MRSA strain with a density of 1 ml 0.5 MacFarland was injected. All rats were scarified in 96th hour, culture samples were taken where intervention was performed and were evaluated microbiologically. Bacteria reproducing in each group were numerically evaluated based on colony-forming unit (CFU/ml) and compared by taking their average. Results: MRSA reproduction of 0 CFU/ml in group 1, of 1410 CFU/ml in group 2, of 180 200 CFU/ml in group 3 and of 625 300 CFU/ml in group 4 was present. A statistically significant difference was present between group 1 and group 4 (p < 0.01), between group 2 and group 4 (p < 0.01), between group 3 and group 4 (p < 0.05). In terms of reproduction, no statistically significant difference was found in group 1, group 2, group 3 in themselves. Conclusions: We observed that the rate of infection increased in the cyanoacyrylate group where cyanoacrylate was used. We think that surgeon should be more careful in using CA in vascular surgery.


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