scholarly journals Factors Associated with SARS-CoV2 Infection and Care Pathways Among the Most Vulnerable Populations Living in Marseille: A Case Control Study

2021 ◽  
Author(s):  
Ismaïl Alsaïdi ◽  
Frédéric De Sousa Santos ◽  
Bérangère Plard ◽  
Elise Janvier ◽  
Aurélie Tinland ◽  
...  
Keyword(s):  
Vulnerable Populations ◽  
Mental Health Problems ◽  
Case Group ◽  
Public Authorities ◽  
Factors Associated ◽  
Younger Age ◽  
Severe Infections ◽  
Collective Housing ◽  
Delay In Seeking Treatment ◽  
Control Study

Abstract Background: Mainland France has been seriously affected by the Covid-19 epidemic, which has brought significant and unexpected morbidity and mortality. Precarious people cared for in accommodation centers are particularly at risk of infection because of collective housing, their dependence on the support system and therefore their difficulty in applying barrier measures. These populations are also subject to a risk of more severe infections or a delay in seeking treatment. This study aims to identify the factors associated with SARS-CoV2 infection in the most vulnerable populations in Marseille.Methods: The sample on which the study was carried out consists of association users, whether or not presenting a symptomatology suggestive of Covid-19, and routinely treated between March 2020 and May 2020. Through univariate and multivariate analyzes, we studied the influence of several variables on morbidity attributable to SARS-CoV2. Results: 64 participants were enrolled in the study with 29 cases and 35 control subject. Median age was 21.16 years old with a younger age in the case group (p < 0.005). Sex ratio was 7. Risk factors of SARS-CoV2 in multivariate analysis were living in a shared apartment and a low compliance for distancing measure. Participants presented frequent mental health problems such as anxiety. Conclusions: The allocation of housing to structures involved with the most precarious people appears to be a decisive factor in the fight against the spread of SARS-CoV2 and therefore deserves more attention from public authorities.

scholarly journals Factors associated with SARS-CoV2 infection and care pathways among the most vulnerable populations living in Marseille: a case control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ismaïl Alsaïdi ◽  
Frédéric De Sousa Santos ◽  
Bérengère Plard ◽  
Elise Janvier ◽  
Aurélie Tinland ◽  
...  
Keyword(s):  
Vulnerable Populations ◽  
Mental Health Problems ◽  
Multivariate Analyses ◽  
Case Group ◽  
Healthcare Team ◽  
Public Authorities ◽  
Female Ratio ◽  
Factors Associated ◽  
Presenting Symptoms ◽  
Collective Housing

Abstract Background The Covid-19 pandemic has led to substantial and unexpected increases in morbidity and mortality in France. Vulnerable populations housed in accommodation centres have a greater risk of infection because collective housing and their dependence on social support services mean it is more difficult to apply preventive measures. They are also at greater risk of developing severe forms of Covid-19 and waiting longer before seeking healthcare (for Covid-19 or other) treatment. We aimed to identify the factors associated with SARS-CoV2 infection in the most vulnerable populations in the city of Marseille. Methods The study sample comprised users of various services provided by the association AAJT in Marseille, France, some presenting symptoms suggestive of Covid-19 and others not. All had routine health surveillance provided by AAJT’s dedicated healthcare team between March 2020 and May 2020. Using univariate and multivariate analyses, we studied the influence of several variables on morbidity associated with Covid-19. Results The study included 64 participants, 29 of whom tested positive for Covid-19 and 35 control subjects. Median age was 21.16 years old. Individuals in the ‘Covid-19 case’ group (p < 0.005) – which included persons testing positive and those suspected of being infected – were younger. The study sample’s male/female ratio was seven. In our multivariate analyses, living in a shared apartment and poor adherence to social distancing measures were factors associated with Covid-19 infection. Furthermore, mental health problems - such as anxiety disorder - were very frequent in the study sample. Conclusions Allocating more and specific housing units to structures providing accommodation services to the most vulnerable people would seem to be a decisive factor in controlling the spread of SARS-CoV2, and deserves more attention from public authorities.

scholarly journals Risk Factors for Post-Intensive Care Syndrome in Family Members (PICS-F) of Adult Patients: A Systematic Review.

2021 ◽  
Author(s):  
Zbigniew Putowski ◽  
Natalia Rachfalska ◽  
Karolina Majewska ◽  
Katarzyna Megger ◽  
Łukasz J. Krzych
Keyword(s):  
Risk Factors ◽  
Intensive Care ◽  
Search Strategy ◽  
Mental Health Problems ◽  
Cochrane Library ◽  
Patient Death ◽  
Factors Associated ◽  
Younger Age ◽  
History Of ◽  
Post Intensive Care Syndrome

Abstract Background: Relatives of critically ill patients who either die or survive the intensive care unit (ICU) may develop substantial mental health problems that are collectively defined as Post-Intensive Care Syndrome in Family (PICS-F). It is important to document in a systematic manner all of the possible risk factors associated with the development of the latter.Methods: By using a systematized search strategy we included studies that focused on PICS-F in relatives of adult ICU patients and reported the risk factors associated with its development. The search was conducted within PubMed, Embase, SCOPUS, clinicaltrials.gov and Cochrane Library on the 2nd of May, 2021. PRISMA guidelines were implemented for appropriate reporting. Results: We included 52 papers covering 8293 relatives. The prevalence of PICS-F varied between 2.5-69%. We identified over 70 different risk factors of PICS-F, among which we distinguished patient-related (n=28), relative-related (n=33) and medical staff-related (n=9) risk factors. Among 17 studies with the highest quality we identified the 7 following factors associated with the development of PICS-F: younger age of a patient, death of a patient, depression in relatives during the ICU stay, history of mental disorders in relatives, being a spouse and low satisfaction with communication & care in the ICU.Conclusions: PICS-F is a highly prevalent phenomenon that may be exacerbated by a number of risk factors. Special attention should be paid to proper identification of susceptible relatives in order to prevent PICS.

scholarly journals Risk factors for cefotaxime resistance in children with pneumonia

2012 ◽  
Vol 52 (5) ◽  
pp. 255
Author(s):  
Anak Agung Made Sucipta ◽  
Ida Bagus Subanada ◽  
Samik Wahab
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Univariate Analysis ◽  
Control Group ◽  
Case Group ◽  
Antimicrobial Use ◽  
Factors Associated ◽  
History Of ◽  
Culture Positive ◽  
Control Study

Background Pneumonia is a health problem in developingcountries, often caused by bacterial agents. The 'Widespreaduse of cefotaxime, a third􀁒generation of cephalosporin, may leadto increased incidence of resistance to this antibiotic. Severalstudies have reported on risk factors associated v.ith resistanceto cefotaxime.Objective To identify risk factors for cefotaxime resistance inchildren 'With pneumonia.Methods We performed a case􀁒control study at Sanglah Hospitalbetween January 2006􀁒December 2010. The case group includedchildren with blood culture􀁒positive pneumonia and resistanceto cefotaxime by sensitivity test. The control group was selectedfrom the same population as the case group, but the bacteriaisolated from these subjects were sensitive to cefotaxime. Wetested the folloMng risk factors for resistance to cefotaxime:age :53 years, microorganism species, history of antimicrobialuse, and history of hospitalization within the prior 3 months.Chi square test and logistic regression analysis were performedto determine any associations between the four potential riskfactors and resistance to cefotaxime. A P<0.05 was consideredto be statistically significant.Results Univariate analysis showed that the risk factors forresistance to cefotaxime were history of antimicrobial use in theprior 3 months (OR 2.79; 95%CI 1.40 to 5.55; P􀁓O.OOI) andhistory of hospitalization Mthin the prior 3 months (OR 5.57;95%CI 1.95 to 15.87; P=<O.OOOl). By multivariate analysis,risk factors associated Mth resistance to cefotaxime were historyof antimicrobial use in the prior 3 months (OR 2.4; 95%CI 1.18to 4.86; P=0.015), history of hospitalization within the prior 3months (OR 4.7; 95%CI 1.62 to 13.85; P􀁓0.004), and historyof breast feeding for less than 2 months (OR 2.3; 95%CI 1.0 to5.4; P􀁓0.042).Conclusion History of antimicrobial use and history ofhospitalization within the prior 3 monthsweresignificantrisk factors for resistance to cefotaxime in children Mth pneumonia.[Paediatr Indanes. 2012;52:255-9].

scholarly journals Predictive indicators of severe COVID-19 independent of comorbidities and advanced age: a nested case−control study

2020 ◽  
Vol 148 ◽  
Author(s):  
Xinjie Li ◽  
Tuohutaerbieke Marmar ◽  
Qiang Xu ◽  
Jing Tu ◽  
Yue Yin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Kidney Injury ◽  
Case Control ◽  
Advanced Age ◽  
Control Group ◽  
Case Group ◽  
Factors Associated ◽  
Nested Case Control ◽  
Control Study

Abstract To determine what exacerbate severity of the COVID-19 among patients without comorbidities and advanced age and investigate potential clinical indicators for early surveillance, we adopted a nested case−control study, design in which severe cases (case group, n = 67) and moderate cases (control group, n = 67) of patients diagnosed with COVID-19 without comorbidities, with ages ranging from 18 to 50 years who admitted to Wuhan Tongji Hospital were matched based on age, sex and BMI. Demographic and clinical characteristics, and risk factors associated with severe symptoms were analysed. Percutaneous oxygen saturation (SpO2), lymphocyte counts, C-reactive protein (CRP) and IL-10 were found closely associated with severe COVID-19. The adjusted multivariable logistic regression analyses revealed that the independent risk factors associated with severe COVID-19 were CRP (OR 2.037, 95% CI 1.078–3.847, P = 0.028), SpO2 (OR 1.639, 95% CI 0.943–2.850, P = 0.080) and lymphocyte (OR 1.530, 95% CI 0.850–2.723, P = 0.148), whereas the changes exhibited by indicators influenced incidence of disease severity. Males exhibited higher levels of indicators associated with inflammation, myocardial injury and kidney injury than the females. This study reveals that increased CRP levels and decreased SpO2 and lymphocyte counts could serve as potential indicators of severe COVID-19, independent of comorbidities, advanced age and sex. Males could at higher risk of developing severe symptoms of COVID-19 than females.

scholarly journals Factors Associated with Chemotherapy Induced Nausea in Cancer Patients: A Case-Control Study

2021 ◽  
Vol 13 (3) ◽  
Author(s):  
Mahnaz Khatiban ◽  
Zahra Khalili ◽  
Mahdi Akbarzadeh ◽  
Mahnaz Moghadarikoosha ◽  
Maryam Seyedtabib
Keyword(s):  
Cancer Patients ◽  
Carbohydrate Intake ◽  
Control Group ◽  
Case Group ◽  
Logistic Regression Models ◽  
Factors Associated ◽  
Convenience Sampling ◽  
Potential Factors ◽  
Specific Odor ◽  
Control Study

Background: Chemotherapy-induced nausea (CIN) is one of the most common and uncomfortable symptoms in cancer patients, and different factors can be associated with it. Objectives: This study aimed to determine different factors associated with CIN in cancer patients. Methods: A total of 144 cancer patients were selected by convenience sampling. The patients at acute phase of chemotherapy were assigned to case group (n = 58) if they had nausea or to control group (n = 86) if they did not have nausea. The patients' data were collected using a researcher-made questionnaire including items on potential factors for CIN through interviews with the patients and according to their medical records. Logistic regression models were used to conduct data analysis, and the correlations in question were expressed as odds ratio (OR) at 95% confidence interval (CI). Results: The results showed that the chance of nausea increased by 6.4, 2.4, 1.2, and 1.5 times in case of expected nausea, pain, carbohydrate intake, and smelling a specific odor, respectively. The increasing nausea-inducing effect of drugs led to increased chance of post-chemotherapy nausea (OR = 2.366). Conclusions: Having pain, expecting nausea, carbohydrate intake, smelling a certain odor, and high emetogenic potential of chemotherapy are effective in the development of CIN.

Evaluation of factors associated with recurrent and/or severe infections in patients with Down's syndrome

2003 ◽  
Vol 79 (2) ◽  
pp. 141-8 ◽  
Author(s):  
Luciana M.A. Ribeiro ◽  
Cristina M. A. Jacob ◽  
Antonio C. Pastorino ◽  
Chong A. E. Kim ◽  
Ângela B. F. Fomin ◽  
...  
Keyword(s):  
Down's Syndrome ◽  
Down’S Syndrome ◽  
Factors Associated ◽  
Severe Infections

scholarly journals Factors associated with preterm birth at Wachemo University Nigist Eleni Mohammed memorial hospital, southern Ethiopia: case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Negeso Gebeyehu Gejo ◽  
Melaku Tesfaye W/mariam ◽  
Biruk Assefa Kebede ◽  
Ritbano Ahmed Abdo ◽  
Abebe Alemu Anshebo ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Antenatal Care ◽  
Medical Records ◽  
Case Control Study ◽  
Southern Ethiopia ◽  
Preterm Neonates ◽  
Factors Associated ◽  
Induced Hypertension ◽  
Control Study

Abstract Background Preterm birth is defined as the birth of a baby before 37 completed weeks of gestation. Worldwide, prematurity is the second foremost cause of death in children under the age of 5 years. Preterm birth also gives rise to short and long term complications. Therefore, the primary aim of this study was to identify the factors associated with preterm birth in Wachemo University Nigist Eleni Mohammed Memorial referral hospital, Hadiya Zone, Southern Ethiopia. Methods An institution-based unmatched case-control study was conducted from July 01, 2018 to June 30, 2019 among mothers who gave birth in Wachemo University Nigest Eleni Mohammed Memorial referral hospital. A retrospective one-year data was retrieved from medical records of mothers with their index neonates. Simple random sampling technique was employed to recruit study participants. SPSS version 20 software was used for data entry and computing statistical analysis. Both bivariable and multivariable logistic regression analyses were used to determine the association of each independent variable with the dependent variable. Odds ratio with their 95% confidence intervals was computed to identify the presence and strength of association, and statistical significance was affirmed if p < 0.05. Result The current study evaluated 213 medical records of mothers with index neonates (71 cases and 142 controls). Urban residency [AOR = 0.48; 95% Cl; 0.239, 0.962], antenatal care follow up [AOR = 0.08; 95 Cl; 0.008, 0.694], premature rupture of membranes [AOR = 3.78; 95% Cl; 1.467, 9.749], pregnancy induced hypertension [AOR = 3.77; 95% Cl; 1.408, 10.147] and multiple pregnancies [AOR = 5.53; 95% Cl; 2.467, 12.412] were the factors associated with preterm birth. More than one-third (36.6%) preterm neonates died in the present study. Conclusions The present study found that urban residency, antenatal care follow up, premature rupture of membranes, pregnancy induced hypertension and multiple pregnancies were factors associated with preterm birth. The mortality among preterm neonates is high. Enhancing antenatal care follow up and early detection and treatment of disorders among pregnant women during antenatal care and undertaking every effort to improve outcomes of preterm birth and reduce neonatal mortality associated with prematurity is decisive.

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