Clinical differences between eosinophilic and non-eosinophilic acute exacerbation of chronic obstructive pulmonary disease (AECOPD), a multicenter cross-sectional study

Abstract Background AECOPD is highly heterogeneous with respect to etiology and inflammation. COPD with higher blood eosinophils is associated with increased readmission rates and better corticosteroid response. However, the clinical features of eosinophilic AECOPD aren’t well explored. Then, the aim of this study was to investigate the clinical differences between eosinophilic and non-eosinophilic AECOPD. Methods A total of 643 AECOPD patients were enrolled in this multicenter cross-sectional study. Finally, 455 were included, 214 in normal eosinophils AECOPD (NEOS-AECOPD) group, 63 in mild increased eosinophils AECOPD (MEOS-AECOPD) group, and 138 in severe increased eosinophils AECOPD (SEOS-AECOPD) group. Then, demographic data, underlying diseases, symptoms, and laboratory findings were collected. Multiple logistic regression was performed to identify the independent factors associated with blood EOS. Correlations between blood EOS and its associated independent factors were evaluated. Results The significant differences in 19 factors, including underlying disease, clinical symptom, and laboratory parameters, were identified by univariate analysis. Subsequently, multiple logistic regression revealed that lymphocytes%, neutrophils% (NS%), procalcitonin (PCT), and anion gap (AG) were associated with blood EOS in AECOPD. Both blood EOS counts and EOS% significantly correlated with lymphocytes%, NS%, PCT, and AG. Conclusions The blood EOS was independently associated with lymphocytes%, NS%, PCT, and AG in AECOPD patients. Lymphocytes% was lower, and, NS%, PCT, and AG were higher in eosinophilic AECOPD. Our results indicate that viral dominant infections probably were the major etiology of eosinophilic AECOPD. Non-eosinophilic AECOPD was more likely associated with bacterial dominant infections. The systemic inflammation in non-eosinophilic AECOPD was more severe.

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Symptoms of Depression and Anxiety, and Screening for Mental Disorders in Migrainous Patients

Cephalalgia ◽

10.1046/j.1468-2982.2003.00461.x ◽

2003 ◽

Vol 23 (2) ◽

pp. 79-89 ◽

Cited By ~ 12

Author(s):

F Kowacs ◽

MP Socal ◽

SC Ziomkowski ◽

VF Borges-Neto ◽

DP Toniolo ◽

...

Keyword(s):

Logistic Regression ◽

Mental Disorders ◽

Healthy Subjects ◽

Univariate Analysis ◽

Cross Sectional Study ◽

Depression And Anxiety ◽

Sectional Study ◽

Cross Sectional ◽

Symptoms Of Depression ◽

Gender Education

The purpose of this clinic-based study was the assessment of symptoms of depression, anxiety, and non-specific psychiatric disorders amongst patients with migraine, compared with healthy subjects and with individuals with a non-neurological chronic disease. A cross-sectional study was carried out in which 178 individuals (migraine 51; psoriasis 35; healthy 92) were submitted to three scales: MADRS (depression), STAI-T (anxiety) and SRQ (screening for mental disorders). The subjects with migraine and psoriasis were from the Out-patient Clinics of Headache and of Dermatology, and the healthy volunteers were persons who were accompanying out-patients in the same hospital. Scores were analysed by MANOVA and by association analysis and logistic regression. Scores of all instruments were higher in the migrainous group, but the univariate analysis of association (using cut-offs) showed significance only for suspicion of mental disorders (SRQ). By logistic regression, variables with strongest association to migraine were gender, education, and SRQ in decreasing order.

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Midnight salivary cortisol secretion and the use of antidepressants were associated with abdominal obesity in women with type 1 diabetes: a cross sectional study

Diabetology & Metabolic Syndrome ◽

10.1186/s13098-019-0481-3 ◽

2019 ◽

Vol 11 (1) ◽

Cited By ~ 1

Author(s):

Eva Olga Melin ◽

Magnus Hillman ◽

Maria Thunander ◽

Mona Landin-Olsson

Keyword(s):

Type 1 Diabetes ◽

Logistic Regression ◽

Abdominal Obesity ◽

Salivary Cortisol ◽

Cross Sectional Study ◽

Cortisol Secretion ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Cross Sectional

Abstract Background Abdominal obesity is a risk factor for cardiovascular disease. The aim was to explore the influence of midnight salivary cortisol (MSC), antidepressants and sex on abdominal obesity in type 1 diabetes (T1D). We controlled for physical inactivity, smoking, depression and alexithymia. Methods Cross sectional study of 190 T1D patients (86 women/104 men, 18–59 years, diabetes duration 1–55 years), consecutively recruited from one specialist diabetes outpatient clinic. Anthropometrics, blood pressure, saliva and blood samples were collected, supplemented with data from electronic medical records. Depression and alexithymia were assessed by self-report instruments. MSC (nmol/l) was categorised into 3 levels: high MSC: (≥ 6.7) (n = 64); intermediate MSC: ≥ 3.7− < 6.7) (n = 64); low MSC (< 3.7) (n = 62). Abdominal obesity was defined as waist circumference (meters) ≥ 0.88 for women and as ≥ 1.02 for men. Multiple logistic regression analyses (Backward: Wald) were performed. The Hosmer and Lemeshow test for goodness-of-fit and Nagelkerke R2 were used to evaluate each multiple logistic regression analysis model. Results The prevalence of abdominal obesity was three times higher in the women than in the men (24% versus 8%) (p = 0.002). Antidepressants were used by 10% of the women and by 4% of the men (p = 0.09). The prevalence of high MSC was 1.7 times higher in the women (43% versus 26%); the prevalence of both intermediate MSC (28% versus 38%) and low MSC (29% versus 36%) were lower in the women (p = 0.048). Significant associations with abdominal obesity were for all 190 patients: female sex (adjusted odds ratio (AOR) 3.4 (confidence interval (CI) 1.4–8.2)) and the use of antidepressants (AOR 4.3 (CI 1.2–14.8)); for the 86 women: high MSC (AOR 18.4 (CI 1.9–181)) and use of antidepressants (AOR 12.2 (CI 2.0–73.6)); and for the 104 men: alexithymia (AOR 5.2 (CI 1.1–24.9)). Conclusions Clear sex differences were demonstrated with a distinct higher prevalence of abdominal obesity, as well as a distinct higher prevalence of high midnight salivary cortisol in the women with type 1 diabetes. High midnight salivary cortisol secretion and the use of antidepressants were independent risk factors for abdominal obesity in the women.

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Relationship between obesity indices and hypertension among middle-aged and elderly populations in Taiwan: a community-based, cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2019-031660 ◽

2019 ◽

Vol 9 (10) ◽

pp. e031660 ◽

Cited By ~ 1

Author(s):

Yen-An Lin ◽

Ying-Jen Chen ◽

Yu-Chung Tsao ◽

Wei-Chung Yeh ◽

Wen-Cheng Li ◽

...

Keyword(s):

Blood Pressure ◽

Logistic Regression ◽

Cross Sectional Study ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Community Based ◽

Cross Sectional ◽

Elderly Populations ◽

Obesity Indices ◽

Northern Taiwan

ObjectiveObesity and hypertension (HTN) have become increasingly prevalent in Taiwan. People with obesity are more likely to have HTN. In this study, we evaluated several anthropometric measurements for the prediction of HTN in middle-aged and elderly populations in Taiwan.DesignCross-sectional observational study.SettingCommunity-based investigation in Guishan Township of northern Taiwan.ParticipantsA total of 396 people were recruited from a northern Taiwan community for a cross-sectional study. Anthropometrics and blood pressure were measured at the annual health exam. The obesity indices included body mass index (BMI), body fat (BF) percentage and waist circumference (WC).Outcome measuresStatistical analyses, including Pearson’s correlation, multiple logistic regression and the area under ROC curves (AUCs) between HTN and anthropometric measurements, were used in this study.ResultsOf the 396 people recruited, 200 had HTN. The age-adjusted Pearson’s coefficients of BMI, BF percentage and WC were 0.23 (p<0.001), 0.14 (p=0.01) and 0.26 (p<0.001), respectively. Multiple logistic regression of the HTN-related obesity indices showed that the ORs of BMI, BF percentage and WC were 1.15 (95% CI 1.08 to 1.23, p<0.001), 1.07 (95% CI 1.03 to 1.11, p<0.001) and 1.06 (95% CI 1.03 to 1.08, p<0.001), respectively. The AUCs of BMI, BF percentage and WC were 0.626 (95% CI 0.572 to 0.681, p<0.001), 0.556 (95% CI 0.500 to 0.613, p=0.052) and 0.640 (95% CI 0.586 to 0.694, p<0.001), respectively.ConclusionsWC is a more reliable predictor of HTN than BMI or BF percentage. The effect of abdominal fat distribution on blood pressure is greater than that of total BF amount.

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Determinants of the intensity of uremic pruritus in patients receiving maintenance hemodialysis: A cross-sectional study

PLoS ONE ◽

10.1371/journal.pone.0245370 ◽

2021 ◽

Vol 16 (1) ◽

pp. e0245370

Author(s):

Jian-Hui Zhao ◽

Qiu-Shuang Zhu ◽

Yi-Wen Li ◽

Li-Li Wang

Keyword(s):

Logistic Regression ◽

Multiple Logistic Regression Analysis ◽

Cross Sectional Study ◽

Maintenance Hemodialysis ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Cross Sectional ◽

Urea Nitrogen ◽

Uremic Pruritus ◽

Hs Crp

Background Uremic pruritus (UP) is a common and frustrating symptom in patients receiving hemodialysis (HD). The majority of patients have mild to moderate itching of the skin, and a small percentage have severe itching, which seriously affects their quality of life and survival rate. However, little is known about factors that influence the intensity of itching in patients. Methods A cross-sectional study on uremic pruritus in male and female patients receiving HD was conducted in September 2019. This study included 148 eligible patients who received HD at the Blood Purification Center of Xinchang County People’s Hospital, Zhejiang Province, China from March 2019 to June 2019. We collected general data consisted of age, sex, body mass index (BMI), place of residence, educational level, diabetes mellitus status and duration of HD; as well as clinical, biochemical indicators, including serum calcium (Ca), serum phosphorus (P), serum albumin (ALB), haemoglobin (Hb), serum intact parathyroid hormone (iPTH), pre-dialysis serum urea nitrogen (BUN), normalized protein catabolic rate (nPCR), urea nitrogen clearance index (KT/V), ferritin (FER) and pre-dialysis serum creatinine (sCR). We also assayed the inflammatory cytokine serum high sensitivity C-reactive protein (hs-CRP). The Five-Dimensional Itching Scale (5DIS) was used to evaluate the degree of skin itching (none, mild, moderate, or severe). We used multiple logistic regression to analyze influencing factors on the degree of skin itching in patients with UP. Results Of the 148 patients, 60 had uremic pruritus (incidence rate, 40.54%). These included 22 cases of mild skin itching (14.86%), 30 of moderate skin itching (20.27%), and 8 of severe skin itching (5.41%). Compared with uremia patients without skin pruritus, patients with UP had higher levels of iPTH, Hb, BUN, nPCR, and hs-CRP. The composition ratio showed significant differences between urban and rural patients with different degrees of skin itching (P = 0.017); moreover, the difference of iPTH and hs-CRP levels were statistically significant (P = 0.009 and < 0.001, respectively). Using no itching as a reference, multiple logistic regression analysis showed that as hs-CRP level increased, the patient’s risks of mild skin itching (odds ratio [OR] = 1.740; 95% confidence interval [CI], 1.061–2.854; P = 0.028), moderate skin itching (OR = 2.8838 95% CI, 1.744–4.718; P < 0.001), and severe skin itching (OR = 9.440; 95% CI, 3.547–25.124; P < 0.001) all increased as well. Compared with urban residents, rural residents have a higher risk of moderate itching (OR = 3.869; 95% CI, 1.099–13.622; P = 0.035). Conclusion Levels of hs-CRP were associated with the intensity of skin itching in patients with UP. Higher hs-CRP levels were closely related to severe skin itching. The relationship between the intensity of skin itching and the environment in maintenance hemodialysis patients needs further clarification.

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Clinical Differences between Eosinophilic and Noneosinophilic Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Multicenter Cross-Sectional Study

Mediators of Inflammation ◽

10.1155/2020/1059079 ◽

2020 ◽

Vol 2020 ◽

pp. 1-9

Author(s):

Guangming Dai ◽

Yajuan Ran ◽

Jiajia Wang ◽

Xingru Chen ◽

Junnan Peng ◽

...

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Regression Analysis ◽

Multiple Logistic Regression Analysis ◽

Cross Sectional Study ◽

Chronic Obstructive ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Cross Sectional ◽

Obstructive Pulmonary Disease ◽

Underlying Diseases

Rationale. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is highly heterogeneous with a plethora of different etiologic factors and inflammatory presentations. COPD with higher blood eosinophil count is associated with increased readmission rates and better corticosteroid responses. However, the clinical features of eosinophilic AECOPD are not well explored. Thus, this study was aimed at exploring the clinical differences between eosinophilic and noneosinophilic AECOPD. Methods. A total of 643 AECOPD patients were enrolled in this multicenter cross-sectional study. Finally, 455 were included, 214 in the normal-eosinophil AECOPD (NEOS-AECOPD) group, 63 in the mild increased-eosinophil AECOPD (MEOS-AECOPD) group, and 138 in the severe increased-eosinophil AECOPD (SEOS-AECOPD) group. Demographic data, underlying diseases, symptoms, and laboratory findings were collected. Multiple logistic regression analysis was performed to identify the independent factors associated with blood eosinophils (EOS). Correlations between blood EOS and its associated independent factors were evaluated. Results. The significant differences in 19 factors, including underlying diseases, clinical symptoms, and laboratory parameters, were identified by univariate analysis. Subsequently, multiple logistic regression analysis revealed that lymphocyte%, neutrophil% (NS%), procalcitonin (PCT), and anion gap (AG) were independently associated with blood EOS in AECOPD. Both blood EOS counts and EOS% were significantly correlated with lymphocyte%, NS%, PCT, and AG. Conclusions. Collectively, blood EOS was independently associated with lymphocyte%, NS%, PCT, and AG in AECOPD patients. Lymphocyte% was lower, and NS%, PCT, and AG were higher in eosinophilic AECOPD. Our results indicate that viral-dominant infections are the probable major etiologies of eosinophilic AECOPD. Noneosinophilic AECOPD is more likely associated with bacterial-dominant infections. The systemic inflammation in noneosinophilic AECOPD was more severe.

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Hyperuricemia and Associated Factors in Children with Chronic Kidney Disease: A Cross-Sectional Study

Children ◽

10.3390/children9010006 ◽

2021 ◽

Vol 9 (1) ◽

pp. 6

Author(s):

Jie Xu ◽

Lingxiao Tong ◽

Jianhua Mao

Keyword(s):

Chronic Kidney Disease ◽

Logistic Regression ◽

Regression Analysis ◽

Kidney Disease ◽

Associated Factors ◽

Multiple Logistic Regression Analysis ◽

Cross Sectional Study ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Cross Sectional

Background: Hyperuricemia is increasingly recognized as a risk factor for chronic kidney disease (CKD) just in adults. The purpose of this study was to investigate the clinical characteristics of hyperuricemia and its associated factors in Chinese children with CKD at a single center. Methods: A cross-sectional study of 170 CKD children collected from the Department of Nephrology, The Zhejiang University Children’s Hospital was conducted. The clinical data, including anthropometric data, blood pressure measurements, and biochemical parameters, were recorded and analyzed retrospectively. The factors associated with hyperuricemia in CKD children were evaluated by Pearson and Spearman correlation analysis and multiple logistic regression analysis. Results: The mean age was 9.79 ± 4.10 years, and 72 (42.35%) were girls. Higher blood urea nitrogen (BUN), serum creatinine, cystatin C, D-dimer, lower hemoglobin, albumin, and estimated glomerular filtration rate (eGFR) were significantly associated with higher serum uric acid (SUA). In multiple logistic regression analysis, anemia and higher BUN were both positively associated factors, whereas eGFR ≥ 90 mL/min/1.73 m2 was a negatively associated factor for subjects with SUA ≥ 390 µmol/L (6.5 mg/dL). Conclusions: SUA was significantly associated with kidney risk factors in CKD children. Monitoring and controlling SUA, Hb, BUN, and Scr levels in CKD children may help to prevent the progression of CKD.

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Faktor-Faktor Yang Mempengaruhi Perilaku Pemeriksaan Payudara Sendiri (SADARI) Pada Mahasiswi Non Kesehatan UIN Antasari Banjarmasin

Jurnal Kesehatan Indonesia ◽

10.33657/jurkessia.v9i2.158 ◽

2019 ◽

Vol 9 (2) ◽

pp. 76

Author(s):

Septi Anggraeni ◽

Eka Handayani

Keyword(s):

Logistic Regression ◽

Family Support ◽

Peer Support ◽

Information Sources ◽

Statistical Tests ◽

Univariate Analysis ◽

Cross Sectional Study ◽

Bivariate Analysis ◽

Multiple Logistic Regression ◽

Cross Sectional

Cancer is one of the leading causes of death worldwide. In Indonesia, more than 80% of breast cancer cases are found at an advanced stage, where treatment is difficult. Therefore, it is necessary to take preventative measures with early diagnosis through regular routine checks, one of which is by Self Breast Examination (BSE). This study was conducted to determine the factors that influence the behavior of BSE in non-medical students UIN Antasari Banjarmasin with a cross sectional study design with a sample of 50 female students. Data processing analysis includes univariate analysis, bivariate analysis and multivariate analysis with multiple logistic regression statistical tests. Descriptively obtained results that only 13 people (26%) did BSE, respondents' knowledge 38% in good category, attitude towards BSE 84% positive, source of information about BSE 22% in many categories, perceptions of family support 28% supporting and perception about peer support 24% supports. To determine the factors that influence BSE, multiple logistic regression statistical tests were performed which showed the results that there was a joint influence between knowledge, exposure to information sources, perceptions of family and peer support on BSE behavior with a large influence of 35.6 %. To improve the behavior of BSE, it is necessary to increase knowledge, information sources, family and peer support together. Keywords : Knowledge, attitude, Family support, Information Exposure, BSE

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The association between FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a among chronic granulocytic leukemia patients treated with imatinib mesylate

F1000Research ◽

10.12688/f1000research.73054.1 ◽

2021 ◽

Vol 10 ◽

pp. 1003

Author(s):

Shinta Oktya Wardhani ◽

Hani Susianti ◽

Puji Rahayu ◽

Yuyun Prabowowati Yueniwati ◽

Jonny Karunia Fajar

Keyword(s):

Logistic Regression ◽

Gene Polymorphism ◽

Imatinib Mesylate ◽

Cross Sectional Study ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Cross Sectional ◽

Chronic Granulocytic Leukemia ◽

Pcr Rflp ◽

Granulocytic Leukemia

Background: The gene FOXO3a has been elucidated to govern the development of chronic granulocytic leukemia (CGL). Moreover, it has been suggested that the levels of FOXO3a in circulation are affected by the FOXO3a rs4946936 gene polymorphism. However, no study has assessed the correlation between the FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a. The objective of this study was to assess the association between the FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a in CGL patients treated with imatinib mesylate. Methods: A cross-sectional study was conducted from February 2019 to February 2020. The genotyping of FOXO3a rs4946936 gene polymorphism was conducted using PCR-RFLP, and the levels of FOXO3a were assessed using ELISA. The association between the FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a were assessed using multiple logistic regression. Results: A total of 60 CGL patients were assessed in our study. Among them, the CC, CT, and TT genotypes of the FOXO3a rs4946936 gene polymorphism were 35.0%, 48.3%, and 16.7% respectively. Our calculation revealed that elevated levels of FOXO3a were found in CGL patients with the CC genotype of the FOXO3a rs4946936 gene polymorphism. While we failed to clarify the association between either the CT or the TT genotype of FOXO3a rs4946936 gene polymorphism and the levels of FOXO3a. Conclusion: Our study identifies that the CC genotype of the FOXO3a rs4946936 gene polymorphism affects the elevated levels of FOXO3a in CGL patients treated with imatinib mesylate.

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DETERMINAN GANGGUAN KAPASITAS FUNGSI PARU-PARU PADA PERAJIN BATU BATA MERAH DI KABUPATEN BADUNG

ARCHIVE OF COMMUNITY HEALTH ◽

10.24843/ach.2021.v08.i01.p02 ◽

2021 ◽

Vol 8 (1) ◽

pp. 16

Author(s):

I Gusti Agung Ayu Vintan Pramesti ◽

Ni Ketut Sutiari

Keyword(s):

Logistic Regression ◽

Cross Sectional Study ◽

Multiple Logistic Regression ◽

Sectional Study ◽

Chi Square ◽

Cross Sectional ◽

Consecutive Sampling

ABSTRAK Perajin batu bata merah merupakan pekerja sektor informal yaitu pekerja harian lepas dan borongan yang berisiko terkena gangguan kapasitas fungsi paru-paru akibat dari paparan debu saat bekerja. Tujuan penelitian ini untuk mengetahui hubungan karakteristik individu dan paparan debu dengan gangguan kapasitas fungsi paru-paru pada perajin batu bata merah di Kabupaten Badung. Desain penelitian ini yaitu analitik kuantitatif dengan metode cross-sectional study. Penentuan sampel dengan metode consecutive sampling yaitu perajin batu bata merah di Kabupaten Badung berjumlah 42 orang. Data umur, durasi kerja, masa kerja, kebiasaan merokok, dan penggunaan alat pelindung diri dikumpulkan menggunakan kuesioner, tinggi badan diukur dengan microtoise, berat badan dengan timbangan berat badan, paparan debu dengan Personal Dust Sampler (PDS), dan gangguan kapasitas fungsi paru-paru dengan spirometer. Data dianalisis secara univariabel, bivariabel dengan uji Chi-square, dan multivariabel dengan multiple logistic regression. Hasil penelitian menujukkan 92,86% perajin mengalami gangguan kapasitas fungsi paru-paru. Analisis multivariabel menunjukkan bahwa paparan debu merupakan variabel yang paling berpengaruh terhadap gangguan kapasitas fungsi paru-paru namun signifikansi rendah (AOR=18,18; CI=1,02-324,8; p=0,004). Sebagai upaya pencegahan gangguan kapasitas fungsi paru-paru, perajin diharapkan lebih peduli terhadap risiko yang dihadapi di tempat kerja dan melakukan upaya pencegahan. Kata kunci: Perajin, Fungsi Paru, Debu

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Several Components of the Lebanese Mediterranean Diet and Particular Sociodemographic, Medical and Lifestyle Factors may be Associated with Gastroesophageal Reflux Disease in Adults: A Cross-sectional Study in a Middle Eastern Setting

Current Nutrition & Food Science ◽

10.2174/1573401316999200518095448 ◽

2020 ◽

Vol 17 (1) ◽

pp. 82-93

Author(s):

Mary-Joe Youssef ◽

Antoine Aoun ◽

Aline Issa ◽

Lana El-Osta ◽

Nada El-Osta ◽

...

Keyword(s):

Logistic Regression ◽

Gastroesophageal Reflux Disease ◽

Perceived Stress ◽

Dietary Habits ◽

Cross Sectional Study ◽

Lifestyle Factors ◽

P Value ◽

Sectional Study ◽

Cross Sectional ◽

Gerd Symptoms

Background: The prevalence of gastroesophageal reflux disease (GERD) is increasing worldwide and the related chronic symptoms can be associated with morbidity and poor quality of life. Objective: The objective of this study was to identify foods and beverages consumed by the Lebanese population, dietary habits, socio-demographic and lifestyle factors, health parameters and perceived stress, implicated in increasing GERD symptoms. Methods: This observational cross-sectional study was carried among Lebanese adults in 2016. A convenient sample of 264 participants was equally divided into a GERD group and a control group. Data on socio-demographic characteristics, lifestyle, health status and dietary habits including Lebanese traditional dishes were collected. The perceived stress scale (PSS) was also used to assess the participants’ perception of stress. Logistic regression analyses were conducted with GERD symptoms (presence or absence) being the dependent variable. Results: The GERD symptoms were significantly associated with age (-p-value=0.017), family history of GERD symptoms (-p-value<0.001), smoking (-p-value=0.003) and chronic medical conditions (-p-value<.001). Regarding the dietary factors, participants who ate three meals or less/day, between meals and outside homes were 2.5, 2.9 and 2.4 times at a higher risk of experiencing GERD symptoms than others, respectively. Moreover, the logistic regression model showed that the GERD symptoms were significantly associated with the consumption of coffee (-p-value=0.037), Lebanese sweets (-p-value=0.027), fried foods (-p-value=0.031), ‘Labneh’ with garlic (-p-value<0.001), pomegranate molasses (-p-value=0.011), and tomatoes (-p-value=0.007). Conclusion: Some specific lifestyle factors and components of the Lebanese Mediterranean diet could be associated with GERD symptoms.

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