scholarly journals Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

2020 ◽  
Author(s):  
Tegenaw Tiruneh ◽  
Teklehymanot Kiros ◽  
Sisay Getu
Keyword(s):  
Blood Cells ◽  
Reference Interval ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Full Term ◽  
Medical Decision ◽  
Hematological Parameter ◽  
Sectional Study ◽  
Cross Sectional ◽  
Term Newborns

Abstract Background: Hematological reference intervals are used for medical decision tools for interpretation of numerical test results. Establishing of hematological interval among newborn babies is very important for the diagnosis of malignancy, anemia, bleeding disorders, and various infections. There is no locally established hematological reference intervals in Ethiopia. Thus, the aim of this study is to established locally determined hematological reference interval among full-term newborns.Methods: A cross sectional study was conducted from February to May 2019 among 151 apparently healthy full-term newborns at Gondar University Hospital. About 3ml of cord blood was obtained for analysis of Hematological parameters and determined by using Sysmex KX-21N (Sysmex Corporation Kobe, Japan) automated analyzer. Median, 2.5th and 97.5th percentiles were computed.Result: Males to female’s ratio was almost equal. All hematological parameter had no statistically significant difference between males and females. The delivery types were not influenced its hematological values. The reference interval of white blood cells, red blood cells, platelets, hemoglobin, hematocrit, mean cell volume, and mean cell hemoglobin were (7.64-22.16) x109/l, (3.69-5.47)x1012/l, (132.74-413.4) x109/l, (13.32-19.64) g/dl and (39.42-58.06)%, (91.6-113.22)fl, and (30.48-38.02)pg, respectively.Conclusion: All hematological reference interval was established from full-term newborns at University of Gondar hospital was different from other studies in Nigeria, Iraq, Pakistan, Nepal, Saudi Arabia and Iran. Therefore, own determined reference value is very important for the clinicians to correctly diagnosis the patients at health facility levels.

scholarly journals To Established Hematological Reference Intervals Among Full-Term Newborn Babies at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study

2020 ◽  
Author(s):  
Tegenaw Tiruneh ◽  
Teklehymanot Kiros ◽  
Sisay Getu
Keyword(s):  
Reference Interval ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Full Term ◽  
Medical Decision ◽  
Hematological Parameter ◽  
Sectional Study ◽  
Cross Sectional ◽  
Term Newborn ◽  
Significant Difference

Abstract Background: Hematological reference intervals are used for medical decision tools for interpretation of numerical test results. Establishing of hematological interval among newborn babies is very important for the diagnosis of malignancy, anemia, bleeding disorders, and various infections. There is no locally established hematological reference intervals in Ethiopia. Thus the aim of this study is to established locally determined hematological reference interval among full-term newborn babies.Methods: A cross sectional study was conducted from February to May 2019 among 151 apparently healthy full-term newborn babies at Gondar University Hospital. About 3ml of cord blood was obtained for analysis of Hematological parameters and determined by using Sysmex KX-21N (Sysmex Corporation Kobe, Japan) automated analyzer. Median, 2.5th and 97.5th percentiles were computed. Result: Males to female’s ratio was almost equal. All hematological parameter had no statistically significant difference between males and females. The delivery types were not influenced its hematological values. Conclusion: Hematological reference interval was established from full-term newborn babies at University of Gondar hospital and was different from other studies in African and Europeans. Therefore, own determined reference value is very important for the clinicians to correctly diagnosis the patients at health facility levels.

scholarly journals A prospective, cross-sectional study to establish age-specific reference intervals for neonates and children in the setting of clinical biochemistry, immunology and haematology: the HAPPI Kids study protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e025897 ◽  
Author(s):  
Monsurul Hoq ◽  
Vicky Karlaftis ◽  
Susan Mathews ◽  
Janet Burgess ◽  
Susan M Donath ◽  
...  
Keyword(s):  
Study Protocol ◽  
Clinical Care ◽  
Reference Interval ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Clinical Samples ◽  
Sectional Study ◽  
Cross Sectional ◽  
Blood Samples ◽  
Age Appropriate

IntroductionThe clinical interpretation of laboratory tests is reliant on reference intervals. However, the accuracy of a reference interval is dependent on the selected reference population, and in paediatrics, the ability of the reference interval to reflect changes associated with growth and age, as well as sex and ethnicity. Differences in reagent formulations, methodologies and analysers can also impact on a reference interval. To date, no direct comparison of reference intervals for common analytes using different analysers in children has been published. The Harmonising Age Pathology Parameters in Kids (HAPPI Kids) study aims to establish age-appropriate reference intervals for commonly used analytes in the routine clinical care of neonates and children, and to determine the feasibility of paediatric reference interval harmonisation by comparing age-appropriate reference intervals in different analysers for multiple analytes.Methods and analysisThe HAPPI Kids study is a prospective cross-sectional study, collecting paediatric blood samples for analysis of commonly requested biochemical, immunological and haematological tests. Venous blood samples are collected from healthy premature neonates (32–36 weeks of gestation), term neonates (from birth to a maximum of 72 hours postbirth) and children aged 30 days to ≤18 years (undergoing minor day surgical procedures). Blood samples are processed according to standard laboratory procedures and, if not processed immediately, stored at –80°C. A minimum of 20 samples is analysed for every analyte for neonates and then each year of age until 18 years. Analytical testing is performed according to the standard operating procedures used for clinical samples. Where possible, sample aliquots from the same patients are analysed for an analyte across multiple commercially available analysers.Ethics and disseminationThe study protocol was approved by The Royal Children’s Hospital, Melbourne, Ethics in Human Research Committee (34183 A). The study findings will be published in peer-reviewed journals and shared with clinicians, laboratory scientists and laboratories.

scholarly journals Establishment of Hematological Reference intervals for healthy Children in Elobied City, Sudan

2021 ◽  
Vol 2 (4) ◽  
pp. 24-31
Author(s):  
Tarig Osman Khalafallah Ahmed ◽  
Malaz Elfatih Abd-elkareem Ahmed ◽  
Ream Elzain Abdelgadir ◽  
Hiba Awadelkareem Osman Fadl ◽  
Assad MA. Babker
Keyword(s):  
Blood Cells ◽  
Hematological Parameters ◽  
Venous Blood ◽  
White Blood Cells ◽  
Reference Interval ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Healthy Population ◽  
Healthy Children ◽  
Cross Sectional

Hemogram Reference intervals are established since a healthy population is critical to accurately interpret laboratory tests, which include Hemoglobin estimation, Red blood cells count and indices, White blood cells count and differential in addition to Platelets count. This study aims to establish the reference interval of the complete hemogram amongst healthy Sudanese children in Elobied city, Sudan. A descriptive cross-sectional study  included 354 healthy children, aged between 3 to 17 years, who were categorized into three groups according to age. A questionnaire was fulfilled, EDTA anti-coagulated venous blood sample was collected from each child then the complete hemogram was performed automated hematological analyzer (Sysmex Xp 300), Finally, Data was analyzed by a software program (SPSS version 21). The hematological reference intervals for healthy children [Hb g/dl, HCT%, RBCs count x106μL, MCV/fL ,MCH /pg., MCHC g/dl ,WBCs count x10³/μL, Neutrophil count%, Eosinophil count %, Basophile count %, lymphocyte count ,Monocytes count%, RDW CV and PLTs count×10³/μL] are [(12.4±1.2),(37±4),(5.0 ±0.4), (82±5.0), (26±3.0), (32±3.0) ,(7.0±2.0) (47±10), (1±0.1) ,(0±0),(45± 10),(7 ± 4), (13±1.8) &(227±91)] respectively. The hematological RI for healthy children in Elobied was established in this study to be representative of this population, there was a significant gender-based difference in all the evaluated hematological parameters, they were found to be higher in males than in females except for basophil (%). Finally, the results of this study would shed a light on the importance of establishing RI for the children population in Elobied.

scholarly journals Skin-to-skin contact between mothers and full-term newborns after birth: a cross-sectional study

2021 ◽  
Vol 74 (suppl 4) ◽  
Author(s):  
Rosely Sayuri Kuamoto ◽  
Mariana Bueno ◽  
Maria Luiza Gonzalez Riesco
Keyword(s):  
Best Practice ◽  
Participant Observation ◽  
Upper Airway ◽  
Cross Sectional Study ◽  
Full Term ◽  
Sectional Study ◽  
Cross Sectional ◽  
Skin Contact ◽  
Term Newborns ◽  
Skin To Skin

ABSTRACT Objective: to analyze skin-to-skin contact practice in full-term newborns after birth. Method: a cross-sectional study carried out in São Paulo-SP with 78 mother-child binomials. Data were obtained from medical records and by non-participant observation. Maternal, neonatal and care conditions, length of skin-to-skin contact and breastfeeding attachment were analyzed. Results: skin-to-skin contact was performed in 94.9% of births, with a mean length of 29 minutes. Births with intact perineum took longer, neonates with Apgar 10, without upper airway aspiration, assisted by a nurse-midwife and with neonatal assistance by a resident in pediatrics. The variables that favor breastfeeding attachment were perineal integrity, newborn with good vitality, without upper airway aspiration and who received professional assistance for breastfeeding attachment. Conclusion: skin-to-skin contact was performed in almost all births, but with less time than recommended as best practice.

Pediatric reference intervals in China (PRINCE): design and rationale for a large, multicenter collaborative cross-sectional study

2018 ◽  
Vol 63 (24) ◽  
pp. 1626-1634 ◽  
Author(s):  
Xin Ni ◽  
Wenqi Song ◽  
Xiaoxia Peng ◽  
Ying Shen ◽  
Yaguang Peng ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Reference Intervals ◽  
Collaborative Cross ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Reference intervals for hemoglobin A1c (HbA1c) in healthy Mexican pregnant women: a cross-sectional study

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Cristina M. Sánchez-González ◽  
Alfredo Castillo-Mora ◽  
Itzel N. Alvarado-Maldonado ◽  
Carlos Ortega-González ◽  
Nayeli Martínez-Cruz ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Hemoglobin A1c ◽  
Cross Sectional Study ◽  
Reference Intervals ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Community based hematological reference intervals among apparently healthy adolescents aged 12-17 years in Mekelle city, Tigrai, northern Ethiopia: A cross sectional study

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0234106
Author(s):  
Hagos Haileslasie ◽  
Aster Tsegaye ◽  
Gebreyohanes Teklehaymanot ◽  
Getachew Belay ◽  
Gebreslassie Gebremariam ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Reference Intervals ◽  
Northern Ethiopia ◽  
Sectional Study ◽  
Community Based ◽  
Cross Sectional ◽  
Mekelle City ◽  
Apparently Healthy

Associations between white blood cells count and obesity in apparently healthy young adults

2020 ◽  
Vol 50 (6) ◽  
pp. 1013-1019
Author(s):  
Fatemeh Ghannadiasl
Keyword(s):  
Young Adults ◽  
Cardiovascular Diseases ◽  
Blood Cells ◽  
White Blood Cells ◽  
Cross Sectional Study ◽  
The Body ◽  
Sectional Study ◽  
Cross Sectional ◽  
Content Type ◽  
Apparently Healthy

Purpose The elevated white blood cells (WBCs) count has been reported to be a predictor of cardiovascular diseases, diabetes, hypertension and metabolic syndrome. This study aims to determine the associations between WBCs count and obesity in apparently healthy young adults. Design/methodology/approach In this cross-sectional study, the authors evaluated the body mass index (BMI) in 392 apparently healthy young adults of both sexes. The WBCs count was measured using standard counter techniques. The inclusion criteria were the agreement to participate in the study, between 18 and 25 years of age, lack of self-reported diseases such as cardiovascular diseases, hypertension, kidney and infectious diseases. Findings According to the BMI classification, underweight and overweight or obesity were observed in 14.58 and 11.48 per cent of young adults, respectively. The mean WBC was 6.5 ± 1.5 (×10³ cells/µL). Higher values of WBCs were found in women than in men (p = 0.02). The young adults with higher BMI had a higher WBCs count. There was a positive correlation between WBCs count and weight and BMI (r = 0.19 and r = 0.22, p < 0.001, respectively). Research limitations/implications This research was a cross-sectional study. Future studies are suggested using longitudinal studies to examine more relationships between obesity and WBCs count in apparently healthy young adults. Practical implications The results of this study provide evidence for weight management in this age group to reduce diseases associated with increased WBCs count. Originality/value The WBCs count was related to increasing levels of BMI per cent 2 C even in the normal range.

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