scholarly journals Availability of laboratory diagnosis of gonorrhoea and its meaning in case reporting in Shandong province, China

2020 ◽  
Author(s):  
Xinlong Chen ◽  
Yanling Gan ◽  
dianchang liu

Abstract Background The aim of this study is to understand the availability of laboratory diagnosis of gonorrhoea in Shandong province and its meaning in case reporting. Methods Two surveys were conducted among hospitals providing clinical services for sexually transmitted infection(STI) in Shandong Province in 2012 and 2018. The availability of laboratory tests for Neisseria gonorrhoeae (NG) and distribution of reported gonorrhea cases were compared among different hospitals provided clinical services for STI in Shandong province. Descriptive analysis and Chi-square were used for statistical analysis. Results Smear, culture and PCR tests for NG were used among 301(74.69%), 123(30.52%), 43(10.67%) hospitals in 2012 and 356(74.48%), 176(36.82%) and 73(15.27%) hospitals in 2018, respectively. Significant differences were observed in the availability of smear among hospitals at different levels (X2 = 12.159, p = 0.000) and with different affiliations(X2 = 4.551, p = 0.033) in 2018. Significant differences were observed in the availability of culture and PCR tests among hospitals at different levels both in 2012 (X2 = 34.532, p = 0.000; X2 = 7.380, p = 0.007) and 2018 (X2 = 49.820, p = 0.000; X2 = 21.658, p = 0.000). The availability of culture and PCR tests for NG among hospitals in 2018 was higher than that in 2012 (X2 = 3.870, p = 0.049; X2 = 4.050, p = 0.044). More hospitals reported gonorrhea cases in 2018 than in 2012 (X2 = 6.768, p = 0.009). A significant difference was observed in distribution of case reporting among hospitals at different levels in 2018 (X2 = 6.975, p = 0.008) and among different types of hospitals both in 2012 (X2 = 52.362, p = 0.000) and 2018 (X2 = 74.478, p = 0.000). Conclusion Poor availability of NG laboratory tests affects case reporting and is a crucial reason leading to high sex ratio and underreporting of gonorrhea cases in Shandong province. Trial registration Not applicable

2020 ◽  
Author(s):  
Xinlong Chen ◽  
Xiongfei Mi ◽  
Yanling Gan ◽  
Degui Chang ◽  
Dianchang Liu

Abstract Background: Gonorrhea, which is caused by the bacterium Neisseria gonorrhea (NG), is a major public health concern worldwide. The aim of this study is to understand the availability of the laboratory diagnosis of gonorrhea in Shandong Province and its meaning in case reporting. Methods: Two surveys were conducted among hospitals providing clinical services for patients with sexually transmitted infections (STIs) in Shandong Province in 2012 and 2018. The availability of laboratory tests for NG and the distribution of reported gonorrhea cases among different hospitals providing clinical services for patients with STIs in Shandong Province were compared. Descriptive analysis and chi-square test were used for statistical analysis. Results: Smear, culture, and PCR tests for NG were used in 301 (74.69%), 123 (30.52%), and 43 (10.67%) hospitals in 2012 and in 356 (74.48%), 176 (36.82%), and 73 (15.27%) hospitals in 2018. Significant differences were observed in the availability of smear tests among hospitals with different levels (X2 = 12.159, p = 0.000) and with different affiliations (X2 = 4.551, p = 0.033) in 2018. Significant differences were observed in the availability of culture and PCR tests among hospitals at different levels in 2012 (X2 = 34.532, p = 0.000; X2 = 7.380, p = 0.007) and 2018 (X2 = 49.820, p = 0.000; X2 = 21.658, p = 0.000). The availability of culture and PCR tests for NG in hospitals in 2018 was higher than that in 2012 (X2 = 3.870, p = 0.049; X2 = 4.050, p = 0.044). More hospitals reported gonorrhea cases in 2018 than that in 2012 (X2 = 6.768, p = 0.009). A significant difference was observed in the distribution of case reporting among hospitals at different levels in 2018 (X2 = 6.975, p = 0.008) and among different types of hospital in 2012 (X2 = 52.362, p = 0.000) and 2018 (X2 = 74.478, p = 0.000). Conclusions: The poor availability of NG laboratory tests affects case reporting and is a crucial reason that leads to the high sex ratio and under-reporting of gonorrhea cases in Shandong Province.


2020 ◽  
Author(s):  
Xinlong Chen ◽  
Tongsheng Chu ◽  
Yanling Gan ◽  
Furong Li ◽  
Degui Chang ◽  
...  

Abstract Background Availability of laboratory testing is the prerequisite for early diagnosis of syphilis. This study aimed to understand the availability of laboratory testing for syphilis among different hospitals in Shandong province. Methods Basic information on hospitals provided clinical health service for sexually transmitted infections in Shandong province and type of laboratory tests for syphilis provided was collected and analyzed using Chi-square test. Results A total of 410 and 456 hospitals provided sexually transmitted infection (STI) clinical services were surveyed in 2012 and 2018, respectively. Significant differences in the availability of nontreponemal tests were observed among hospitals with different levels (X 2 =6.624, p=0.010) and types (X 2 =17.752, p=0.001) in 2012 but not in 2018. A significant difference in the availability of treponemal tests was observed at different levels in 2012 (X 2 =9.937, p=0.002) but not in 2018. Significant differences in the availability of nontreponemal tests, titre of nontreponemal tests, and treponemal tests were observed among hospitals with different affiliations in 2018 (p=0.000; X 2 =15.274, p=0.000; p=0.021) but not in 2012. The availability of both nontreponemal test and treponemal test for syphilis among hospitals in 2018 was higher than that in 2012 (90.13% vs. 57.56%, X 2 =121.219, p=0.000). Conclusions Further efforts are needed to reduce the disparity in availability of laboratory testing for syphilis among different hospitals in China.


2013 ◽  
Vol 3 (2) ◽  
pp. 32-35 ◽  
Author(s):  
Apeksha Mainali

Introduction: Intra-oral and extra-oral tissues are at risk of damage during orthodontic treatment, most commonly oral ulcerations. Clinicians should assess and monitor every aspect of patient’s treatment procedure to achieve an uneventful and successful final result. Objective: To evaluate occurrence of oral ulcerations in patients undergoing orthodontic treatment. To evaluate the most common type of ulceration and to assess the management of such ulcerations by the orthodontists. Materials & Method: A questionnaire-based study was used among Nepalese and international orthodontists. Data were analyzed statistically using descriptive analysis and Chi-square test, p<0.05 was considered to be significant with a confidence interval of 95%. Result: Most common oral ulceration encountered during orthodontic treatment was traumatic ulceration which was managed by symptomatic measures. There was a statistically significant difference in the method of education to the patients among national and international orthodontists. Conclusion: Careful use of instruments, careful fitting and adjustment of the appliances should be done to avoid oral ulcerations during orthodontic treatment. Topical medicines can be used for management of such ulcers. Nepalese orthodontists should focus on using audio-visual aids for patient education as it has great promise in enhancing patient understanding and in prompting behavioral change.  


2005 ◽  
Vol 16 (1) ◽  
pp. 31-34 ◽  
Author(s):  
Michelle Alfa

Chancroid is a sexually transmitted infection caused byHaemophilus ducreyi. This fastidious, Gram-negative coccobacilli dies rapidly outside the human host, making diagnostic testing using culture methods difficult. This genital ulcer infection is not common in Canada and, therefore, can often be misdiagnosed. The objective of the present paper is to provide practical approaches for the diagnosis of chancroid in Canadian patients where the prevalence of this infection is low. Issues related to sample collection, sample transport and available diagnostic tests are reviewed, and several alternative approaches are outlined. Although antigen detection, serology and genetic amplification methods have all been reported forH ducreyi, none are commercially available. Culture is still the primary method available to most laboratories. However, the special media necessary for direct bedside inoculation is often not available; therefore, communication with the diagnostic laboratory and rapid specimen transport are essential when chancroid is suspected


2017 ◽  
Vol 9 (6) ◽  
pp. 716-720 ◽  
Author(s):  
Michael S. Beeson ◽  
Stanley J. Hamstra ◽  
Melissa A. Barton ◽  
Kenji Yamazaki ◽  
Francis L. Counselman ◽  
...  

ABSTRACT Background  In 2013, milestone ratings became a reporting requirement for emergency medicine (EM) residency programs. Programs rate each resident in the fall and spring on 23 milestone subcompetencies. Objective  This study examined the incidence of straight line scoring (SLS) for EM Milestone ratings, defined as a resident being assessed the same score across the milestone subcompetencies. Methods  This descriptive analysis measured the frequencies of SLS for all Accreditation Council for Graduate Medical Education (ACGME)–accredited EM programs during the 2015–2016 academic year. Outcomes were the frequency of SLS in the fall and spring milestone assessments, changes in the number of SLS reports, and reporting trends. Chi-square analysis compared nominal variables. Results  There were 6257 residents in the fall and 6588 in the spring. Milestone scores were reported for 6173 EM residents in the fall (99% of 6257) and spring (94% of 6588). In the fall, 93% (5753 residents) did not receive SLS ratings and 420 (7%) did, with no significant difference compared with the spring (5776 [94%] versus 397 [6%]). Subgroup analysis showed higher SLS results for residents' first ratings (183 of 2136 versus 237 of 4220, P &lt; .0001) and for their final ratings (200 of 2019 versus 197 of 4354, P &lt; .0001). Twenty percent of programs submitted 10% or more SLS ratings, and a small percentage submitted more than 50% of ratings as SLS. Conclusions  Most programs did not submit SLS ratings. Because of the statistical improbability of SLS, any SLS ratings reduce the validity assertions of the milestone assessments.


Author(s):  
Ritanjali Majhi

This study identifies factors responsible for customers’ attitudes and perceptions towards emerging internet banking sector. It also reveals the importance of the key variables relating to customers’ demographic and social inputs. A sample of 156 customers is personally surveyed using a structured questionnaire in various cities of Andhra Pradesh. The data are analyzed using descriptive analysis like chi-square test, cross tabulations, t-test and factor analysis, and the proposed hypotheses are tested. Further the effects of psychometric factors are analyzed and the results are compared with those obtained without psychometric input. Extensive analysis of the data reveals that factors such as customer relationship management, word of mouth and the attitudes of the customers play important roles in increasing the productivity with respect to internet banking. Hypothesis tests also demonstrate that significant difference exists in usage of mobile banking and SMS banking with reference to demographic factors. The quality of the service also influences the customers to choose internet banking as a better alternative.


2017 ◽  
Vol 28 (12) ◽  
pp. 1164-1168 ◽  
Author(s):  
JeeYoon Park ◽  
Lindsay Zimmerman ◽  
Kelly Stempinski ◽  
Rebecca Bridge ◽  
Alicia Roston ◽  
...  

This study is a follow-up observational study to assess the prevalence of chlamydia (CT) and gonorrhea (GC) among women who undergo a first-trimester surgical termination in a large public, urban hospital-based termination clinic, and to compare the rates to previously published data. We conducted a retrospective chart review on 4197 patients who underwent CT and GC testing before an elective, first-trimester surgical termination between 1 June 2014 and 31 May 2015. The prevalence rates were calculated and compared by chi square tests to previously published data from 1 January 2006 to 30 June 2006 from the same publicly-funded pregnancy termination clinic. Our study population comprised mostly of African Americans (86.8%), and more than half were aged less than 25 years. The overall prevalence of CT in our population was 9.6%, which was significantly different to the prevalence of 11.4% in 2006 ( p value = 0.03). The overall prevalence of GC in our population was 1.9%, which was not significantly different to the prevalence of 2.6% in 2006. To conclude, this study demonstrates the high prevalence rate of CT-positive and GC-positive patients in our publicly-funded pregnancy termination clinic. The prevalence of infection with CT and GC in our study is higher than in other family planning clinics. Regular screening of all patients who undergo induced termination in pregnancy termination clinics can provide a valuable opportunity for physicians to counsel patients about sexually transmitted infection prevention and treatment prior to the procedure or distribution of medications.


1998 ◽  
Vol 9 (1) ◽  
pp. 21-24 ◽  
Author(s):  
Stephen P Higgins ◽  
Paul E Klapper ◽  
J Keith Struthers ◽  
Andrew S Bailey ◽  
Alison P Gough ◽  
...  

Summary: We evaluated Cobas AmplicorTM, a highly automated polymerase chain reaction (PCR) system, to test first-void urine (FVU) and urethral swab specimens for Chlamydia trachomatis and Neisseria gonorrhoeae in men attending a sexually transmitted infection (STI) clinic. Results were compared against an inhouse radioimmune dot blot (DB) test for C. trachomatis and selective culture for N. gonorrhoeae . Three hundred and ninety sets of specimens were obtained from 378 consecutive new and returned-new patients. Gonorrhoea prevalence was 9.49%, with no significant difference in sensitivity or specificity between culture and PCR. Chlamydia prevalence was 15.4%, with sensitivities of: DB 55%, PCR of FVU 86.7%, urethral swab PCR 90%. The specificity of PCR on FVU and urethral swabs was 100%. We have shown that Cobas AmplicorTM PCR is highly sensitive and specific in the diagnosis of chlamydia and gonorrhoea in men attending an STI clinic. Further economic and scientific studies are needed to determine the costeffectiveness of this technique for screening in primary care settings.


2003 ◽  
Vol 14 (5) ◽  
pp. 307-308 ◽  
Author(s):  
Anna M McNulty ◽  
Richard Rohrsheim ◽  
Basil Donovan

To determine the impact of the Olympic Games the Sydney Sexual Health Centre database was accessed for demographic, health care utilization, and morbidity variables for two periods of interest: 15-29 September 2000 (the 'Olympic period'), and 1-30 September 1999 ('1999 comparison period'). Differences were tested by chi-square statistics and by calculation of odds ratios (ORs) using SPSS. During the Olympic period twice as many of the new patients had arrived in Australia that year (35% c.f. 18%: OR 2.46, 95% CI 1.49-4.05, P=0.0002). Per attendance the proportion with symptoms or a known sexually transmitted infection (STI) contact was higher during the Games (29% c.f. 16% OR 1.67, 95% CI 1.1.27-2.21, P=0.0002) and there was a marginally higher yield of bacterial STIs (6% c.f. 3%: OR 1.83, 95% CI 1.06-3.13 P=0.03). The normal clinic population was replaced by an increased proportion of symptomatic patients who were recent arrivals in Australia.


2014 ◽  
Vol 2 (3) ◽  
pp. 34-37 ◽  
Author(s):  
C Adhikari ◽  
L Sherchan ◽  
SB Thapa ◽  
LM Adhikari

INTRODUCTION: Auxiliary Health Workers (AHWs) are the undergraduate 2nd  class health workforce of Nepal. Syndromic Sexually Transmitted Infection Case Management/Reproductive Health (SSCM/RH) training for AHWs is designed to develop knowledge, attitude and skills. The purpose of this study was to examine the effectiveness of the training in knowledge and practice of AHWs. MATERIAL AND METHODS: Achham district from where all AHWs were purposively selected for cross-sectional study. Total number of trained AHWs was 35 and untrained was 19, who were interviewed to fulfill the structured pretested questionnaire that included knowledge inventory and self reported practice.The data collected from29th May to 25th July, 2005. Written consent was taken from respondents after permission taken from Achham DHO. Statistical tests used were mean, median, SD, Mann-Whitney U test, Spearman's rho and chi-square. Values with p < 0.05 was considered significant. RESULTS : All AHWs were male, with mean age of 32.1 years. Regarding knowledge, the scores in all syndromes diagnosis and treatment regimen were significantly different in two groups except in two syndromes. Two practices were found significant. The median knowledge score was 20 (IQR, 16-22) and 16 (IQR, 12-20) in trained and untrained respectively. Similarly, median practice score was found 14 (IQR, 10-16) and 7 (IQR, 6-9) in trained and untrained respectively. In aggregate, both the practice score (U=38.5, p<0.001, two-tailed) and the knowledge score (U=205, p=0.020, two-tailed) of trained group significantly differed from that of untrained. Knowledge and practice score was also found positively and moderately correlated (P=0.616, p<0.001, two-tailed).CONCLUSION: The training was effectivein bringing about changes both in knowledge and practice of AHWs. The higher the knowledge level, the higher the practice level.DOI: http://dx.doi.org/10.3126/jucms.v2i3.11826 Journal of Universal College of Medical Sciences Vol.2(3) 2014: 34-37


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