The association between serum uric acid and controlled attenuation parameter in United States adults without hepatitis B and C: a cross-sectional study

Abstract Background: Controlled attenuation parameter (CAP) is a kind of widespread popular parameter to evaluate various types of hepatic steatosis by liver ultrasound transient elastography. We investigated the relationship between serum uric acid (SUA) and CAP without hepatitis B and C virus-infected in the United States adults, data from National Health and Nutrition Examination Survey (NHANES).Methods: The present study was cross-sectional research. 4319 American men and women participants ≥18 years old, without B and C hepatitis, were included in our analysis. There are some measures to evaluate the association between SUA and CAP by multivariate logistic regression analyses, fit smoothing curves, generalized additive models, two-piecewise linear regression model and subgroup analyses.Results: There was a positive association between the value of SUA and CAP by multivariate logistic regression analyses after adjusting for various confounders. Besides, the inflection point of non-linear curve relationship was identified as 4.3 mg/dL, for SUA <4.3 mg/dL, the effect size is 10.6 (P< 0.01); Correspondingly, SUA≥ 4.3 mg/dL, the effect size is 4.3 (P< 0.01).Finally, SUA was positively associated with glycohemoglobin less than 6.5% individuals (β =7.3, P< 0.01) and Fasting glucose less than 7.0 mmol/L individuals (β = 6.8, P< 0.01) in the subgroup analysis. Conclusions: Our research found the relationship between SUA and CAP is non-linear. Subgroup analysis indicated that the positive association between SUA and CAP were showed in non-diabetic patients but not in diabetic.

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Patterns of Immigration and Public Assistance Utilization, 1970–1980

International Migration Review ◽

10.1177/019791838802200103 ◽

1988 ◽

Vol 22 (1) ◽

pp. 51-83 ◽

Cited By ~ 6

Author(s):

Leif Jensen

Keyword(s):

United States ◽

Logistic Regression ◽

Public Assistance ◽

Immigrant Families ◽

The United States ◽

Regression Analyses ◽

Multivariate Logistic Regression ◽

Cross Sectional ◽

Race Ethnicity ◽

To Receive

The recent surge in immigration to the United States has rekindled debate over the economic burden imposed by immigrants. This article explores the utilization of public assistance by immigrants and natives. The analysis goes beyond existing research by utilizing repeated cross-sectional data. Descriptive tables show that despite their higher poverty rates, immigrant families had only minimally higher public assistance recipiency rates compared to natives. Multivariate logistic regression analyses reveal that immigrant families were generally less likely than natives to receive public assistance, other things equal. There were exceptions to this generalization according to year of observation and race/ethnicity.

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Mild behavioral impairment is related to frailty in cognitively normal older adults: a cross-sectional study

10.21203/rs.3.rs-34750/v1 ◽

2020 ◽

Author(s):

Shaoyi Fan ◽

Ximin Liang ◽

Tianchan Yun ◽

Zhong Pei ◽

Bin Hu ◽

...

Keyword(s):

Older Adults ◽

Logistic Regression ◽

Neuropsychiatric Symptoms ◽

Cross Sectional Study ◽

Sectional Study ◽

Multivariate Logistic Regression ◽

Behavioral Impairment ◽

Cross Sectional ◽

Cognitively Normal ◽

The Relationship

Abstract Background: Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a neurobehavioral syndrome characterized by later-life emergence of sustained neuropsychiatric symptoms, has yet to be elucidated.We aimed to evaluate the associations between mild behavioral impairment and frailty in cognitively normal older adults.Methods: This is a cross-sectional study. A consecutive series of 137 cognitively normal older adults in the Anti-Aging study, recruited from primary care clinics, were enrolled. Frailty was estimated using the original Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist at a cut-off point of >8 (optimizing sensitivity and specificity), which was developed to assess emergent neuropsychiatric symptoms in accordance with the MBI criteria. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariate logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status.Results: At baseline, 30.6% of the older adults had frailty, 35.0% had prefrailty and 18.2% had MBI (MBI+ status). Multivariate logistic regression analysis demonstrated that compared to MBI- status (without MBI), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, p = 0.02). The frailty and MBI categories were both significantly associated with both MMSE and MoCA-BC score (p<0.05).Conclusions: Both frailty and MBI status are related to higher risk of cognitive impairment. MBI is significantly associated with an increased risk of having frailty before overt cognitive impairment. This association merits further study to identify strategies to the early detection, prevention and therapeutic intervention of frailty.

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Mild behavioral impairment is related to frailty in non-dementia older adults: a cross-sectional study

10.21203/rs.3.rs-34750/v2 ◽

2020 ◽

Author(s):

Shaoyi Fan ◽

Ximin Liang ◽

Tianchan Yun ◽

Zhong Pei ◽

Bin Hu ◽

...

Keyword(s):

Older Adults ◽

Logistic Regression ◽

Neuropsychiatric Symptoms ◽

Cross Sectional Study ◽

Sectional Study ◽

Multivariate Logistic Regression ◽

Behavioral Impairment ◽

Cross Sectional ◽

Increased Risk ◽

The Relationship

Abstract Background: Frailty and cognitive decline are highly prevalent among older adults. However, the relationship between frailty and mild behavioral impairment (MBI), a neurobehavioral syndrome characterized by later-life emergence of sustained neuropsychiatric symptoms, has yet to be elucidated.We aimed to evaluate the associations between mild behavioral impairment and frailty in non-dementia older adults.Methods: This is a cross-sectional study. A consecutive series of 137 non-dementia older adults in the Anti-Aging Study, recruited from primary care clinics, were enrolled. Frailty was estimated using the Fried phenotype. MBI was evaluated by the Mild Behavioral Impairment Checklist at a cut-off point of >8 (optimizing sensitivity and specificity), which was developed to assess emergent neuropsychiatric symptoms in accordance with the MBI criteria. Cognition was assessed with the Chinese versions of the Montreal Cognitive Assessment (MoCA-BC) and Mini-mental State Examination (MMSE). Multivariate logistic regression was performed to estimate the relationship between MBI and objective cognition with frailty status.Results: At baseline, 30.7% of the older adults had frailty and 18.2% had MBI (MBI+ status). Multivariate logistic regression analysis demonstrated that compared to MBI- status (without MBI), MBI+ was more likely to have frailty (odds ratio [OR] = 7.44, 95% CI = 1.49-37.21, p = 0.02).Conclusions: MBI is significantly associated with an increased risk of having frailty before the presence of overt dementia. This association merits further study to identify strategies for the early detection, prevention and therapeutic intervention of frailty.

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The rate of child restraint system use among children aged under six years in China

Scandinavian Journal of Public Health ◽

10.1177/14034948211036621 ◽

2021 ◽

pp. 140349482110366

Author(s):

Xiaoguo Zheng ◽

Ruili Li ◽

Huimin Yang ◽

Delu Yin ◽

Tao Yin ◽

...

Keyword(s):

Logistic Regression ◽

Multivariate Logistic Regression Analysis ◽

Positive Association ◽

Public Health Education ◽

Restraint System ◽

Multivariate Logistic Regression ◽

Significant Positive Association ◽

Cross Sectional ◽

Child Restraint ◽

Child Restraint System

Aims: The child restraint system (CRS) for vehicles is designed to provide specialized protection for children in the event of a crash. The aim of the study was to investigate the rate of CRS use and analyze the factors associated with CRS use among children aged under six years in China, and to provide further insight into developing strategies for promoting public health education. Methods: This is a cross-sectional study. The study sites were 36 primary healthcare institutions in 12 provinces across China, and the participants were 34,503 guardians of children aged 0–6 years. Guardians who owned private cars were included and completed surveys about their experience using CRS. Odds ratios and 95% confidence intervals were calculated using multivariate logistic regression models. Results: The overall rate of CRS use among children aged under six years in China was 17.3%. Multivariate logistic regression analysis revealed that living in an urban area, low age of the child, guardians having higher education and being looked after by parents had a significant positive association with CRS use among children aged under six years. Conclusions: This study confirms that there is a low rate of CRS use among children aged under six years in China, highlighting the considerable need for CRS use education, advocacy and promotion of increasing use.

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Prescription drug co-payments and cost-related medication underuse

Health Economics Policy and Law ◽

10.1017/s1744133107004380 ◽

2008 ◽

Vol 3 (1) ◽

pp. 51-67 ◽

Cited By ~ 30

Author(s):

TODD H. WAGNER ◽

MICHELE HEISLER ◽

JOHN D. PIETTE

Keyword(s):

Logistic Regression ◽

Chronic Conditions ◽

Chronic Condition ◽

Positive Association ◽

Nationwide Survey ◽

Multivariate Logistic Regression ◽

Pharmaceutical Spending ◽

Strong Positive Association ◽

The Relationship ◽

Effectiveness Data

AbstractCo-payments have been linked to the slowing growth in pharmaceutical spending over the last five years. However, patients with health problems frequently have difficulty affording their pharmacotherapy and fail to take their medication as prescribed. We examine the relationship between co-payment amounts and four types of cost-related underuse: taking fewer doses, postponing taking a medication, failing to fill a prescription at all, and taking medication less frequently than prescribed. We conducted a nationwide survey of US adults age 50 and over who take medication for a chronic condition. Participants provided information on 17 chronic conditions, medication they take for those conditions, and whether they underused any medication due to cost. We analyzed those who reported paying co-payments for their prescriptions (n = 2,869). Analysis involved multivariate logistic regression, with adjustments for survey weights and clustering. Our data show a strong positive association between co-payments and cost-related medication underuse. Although people differ in how they underuse medications, these behaviours are strongly associated with co-payment amount. Realigning the co-payments with cost-effectiveness data, also known as value-based insurance design, warrants further investigation.

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The Role of Pain-Related Cognitions in the Relationship Between Pain Severity, Depression, and Pain Interference in a Sample of Primary Care Patients with Both Chronic Pain and Depression

Pain Medicine ◽

10.1093/pm/pnz363 ◽

2020 ◽

Vol 21 (10) ◽

pp. 2200-2211

Author(s):

Elisabet Sánchez-Rodríguez ◽

Enric Aragonès ◽

Mark P Jensen ◽

Catarina Tomé-Pires ◽

Concepció Rambla ◽

...

Keyword(s):

Primary Care ◽

Chronic Pain ◽

Pain Catastrophizing ◽

Positive Association ◽

Pain Severity ◽

Pain Interference ◽

Regression Analyses ◽

Depression Severity ◽

Cross Sectional ◽

The Relationship

Abstract Objective The aims of this study were twofold: 1) to better understand the associations between pain-related cognitions and pain severity, and psychological and physical function, and 2) to determine the extent to which these cognitions function as mediators in the association between pain severity and depression in a sample of primary care adult patients with chronic pain and depression. Design Cross-sectional design. Methods Three hundred twenty-eight patients with both depression and chronic pain from primary care centers responded to measures of pain severity, pain interference, depression severity, and pain-related cognitions (including measures of catastrophizing and other pain-related beliefs). We performed three hierarchical regression analyses and two multiple regression analyses. Results The helplessness domain of pain catastrophizing was positively associated with pain severity, depression severity, and pain interference and mediated the relationship between depression and pain severity and vice versa. Beliefs about disability showed a positive association with pain severity, pain interference, and depression severity, and also mediated the relationship between pain severity and depression. Believing in a medical cure was positively associated with pain interference and negatively associated with depression; emotion beliefs were positively associated with pain severity. Conclusions These findings provide important new information about the associations between several pain-related cognitions and pain severity, depression, and pain interference and the potential mediating roles that these cognitions play in the associations between pain severity and depression in patients with both chronic pain and depression in the primary care setting.

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Substance Use among Spanish Adolescents: The Information Paradox

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17020627 ◽

2020 ◽

Vol 17 (2) ◽

pp. 627 ◽

Cited By ~ 3

Author(s):

Angel Belzunegui-Eraso ◽

Inma Pastor-Gosálbez ◽

Laia Raigal-Aran ◽

Francesc Valls-Fonayet ◽

Sonia Fernández-Aliseda ◽

...

Keyword(s):

Logistic Regression ◽

Binge Drinking ◽

Cross Sectional Study ◽

Consumption Patterns ◽

Regression Analyses ◽

Sectional Study ◽

Cross Sectional ◽

The Relationship ◽

Prevalence Ratios ◽

Smoke Tobacco

This aim of this paper is to determine the relationship between the consumption of tobacco, cannabis, and alcohol (including drunkenness and binge drinking consumption patterns) in the previous 30 days by Spanish adolescents and the information that is available to adolescents on drug consumption. This cross-sectional study employed data from the Survey on Drug Use in Secondary Education in Spain (ESTUDES 2016), which was conducted on students aged 14 to 18 (n = 35,369). Contingency tables, mean comparison tests, and logistic regression analyses were conducted and prevalence ratios (PR) were obtained. The results show that the probability that an adolescent will smoke tobacco is associated with whether their mother and/or father smoke (PR: 1.30), whether some of their friends smoke (PR: 14.23), whether the majority of their friends smoke (PR: 94.05) and how well informed they perceive themselves to be (PR: 1.30). Cannabis use is mainly associated with whether most of their friends also use cannabis (PR: 93.05) and whether they are sufficiently informed regarding this consumption (PR: 1.59). Alcohol consumption is associated with whether their mothers drink regularly (PR: 1.21), whether most of their friends drink (PR: 37.29), and whether they are well informed (PR: 1.28). Getting drunk and binge drinking are associated with whether their friends have these behaviors (PR: 44.81 and 7.36, respectively) and whether they are sufficiently informed (PR: 1.23 for both behaviors). In conclusion, the consumption of these substances is more frequent among Spanish adolescents who believe that they are better informed and whose friends have similar patterns of consumption.

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Product Brand Loyalty and Purchase Decision

International Journal of Entrepreneurial Research ◽

10.31580/ijer.v3i3.1504 ◽

2020 ◽

Vol 3 (3) ◽

pp. 76-87

Author(s):

Muhammad Naeem ◽

Abdul Sami

Keyword(s):

Brand Loyalty ◽

Quantitative Research ◽

Research Study ◽

Positive Association ◽

Perceived Quality ◽

Purchase Decision ◽

Cross Sectional ◽

Business World ◽

Multiple Variables ◽

The Relationship

The present study was an examination of the relationship between product brand loyalty and purchase decision of automotive customers. The study focused on comparative analysis of two famous brands of automobile i-e Honda City and Toyota Corolla Xli and the various effects of product brand loyalty on purchase decision of automotive customers. A cross sectional quantitative research design was employed in the research study. In today’s competitive business world, now most of the marketers and manufacturers of various brands have encountered with multiple variables through which they can not only influence the purchase decision of their customers but also secure their buying preferences. The variables that are used and relevant to this study are product brand loyalty, perceived quality, price, and purchase decision. During examination of the relationship between these variables, study investigated that there is a positive association between product brand loyalty, product perceived quality, price and purchase decision.

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785 Reported Restful Sleep Predicting Emotional Distress: Does Exercise (and its modalities) moderate?

SLEEP ◽

10.1093/sleep/zsab072.782 ◽

2021 ◽

Vol 44 (Supplement_2) ◽

pp. A305-A306

Author(s):

Jesse Moore ◽

Ellita Williams ◽

Collin Popp ◽

Anthony Briggs ◽

Judite Blanc ◽

...

Keyword(s):

Logistic Regression ◽

Aerobic Exercise ◽

Regression Models ◽

Regression Analyses ◽

Logistic Regression Models ◽

The Past ◽

Strengthening Exercise ◽

Waking Up ◽

The Relationship ◽

Age And Sex

Abstract Introduction Literature shows that exercise moderates the relationship between sleep and emotional distress (ED.) However, it is unclear whether different types of exercise, such as aerobic and strengthening, affect this relationship differently. We investigated the moderating role of two types of exercise (aerobic and strengthening) regarding the relationship between ED and sleep. Methods Our analysis was based on data from 2018 National Health Interview Survey (NHIS), a nationally representative study in which 2,814 participants provided all data. Participants were asked 1) “how many days they woke up feeling rested over the past week”, 2) the Kessler 6 scale to determine ED (a score >13 indicates ED), and 3) the average frequency of strengthening or aerobic exercise per week. Logistic regression analyses were performed to determine if the reported days of waking up rested predicted level of ED. We then investigated whether strengthening or aerobic exercise differentially moderated this relationship. Covariates such as age and sex were adjusted in the logistic regression models. Logistic regression analyses were performed to determine if subjective reporting of restful sleep predicted level of ED. We investigated whether strengthening exercise or aerobic exercise differentially moderated this relationship. Covariates such as age and sex were adjusted in the logistic regression models. Results On average, participants reported 4.41 restful nights of sleep (SD =2.41), 3.43 strengthening activities (SD = 3.19,) and 8.47 aerobic activities a week (SD=5.91.) We found a significant association between days over the past week reporting waking up feeling rested and ED outcome according to K6, Χ2(1) = -741, p= <.001. The odds ratio signified a decrease of 52% in ED scores for each unit of restful sleep (OR = .48, (95% CI = .33, .65) p=<.001.) In the logistic regression model with moderation, aerobic exercise had a significant moderation effect, Χ2(1) = .03, p=.04, but strengthening exercise did not. Conclusion We found that restful sleep predicted reduction in ED scores. Aerobic exercise moderated this relationship, while strengthening exercise did not. Further research should investigate the longitudinal effects of exercise type on the relationship between restful sleep and ED. Support (if any) NIH (K07AG052685, R01MD007716, K01HL135452, R01HL152453)

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Low Serum Uric Acid Predicts Risk of a Composite Disease Endpoint

Medicina ◽

10.3390/medicina57040361 ◽

2021 ◽

Vol 57 (4) ◽

pp. 361

Author(s):

Fatma Özpamuk-Karadeniz ◽

Yusuf Karadeniz ◽

Adnan Kaya ◽

Servet Altay ◽

Günay Can ◽

...

Keyword(s):

Logistic Regression ◽

Uric Acid ◽

Serum Uric Acid ◽

Density Lipoprotein ◽

Positive Association ◽

Composite Endpoint ◽

Adverse Outcomes ◽

Inverse Association ◽

Adjusted Logistic Regression ◽

Low Serum

Background and objectives: Mortality may increase in hypouricemia as well as inhyperuricemia. We assessed the predictive value of low serum uric acid (SUA) levels on the risk of overall mortality or a composite endpoint of death and nonfatal events. Materials and Methods: In 1013 community-based middle-aged adults, free of uncontrolled diabetes and coronary heart disease at baseline, the association of sex-specific SUA tertiles with defined outcomes was evaluated prospectively by logistic regression, stratified to gender and presence of type-2 diabetes, using recent criteria. Results: Totally, 43 deaths and additional incident nonfatal events in 157 cases were recorded at a median 3.4 years’ follow-up. Multivariable linear regression disclosed SUA to be significantly associated among non-diabetic individuals positively with creatinine, triglycerides, and body mass index in women further with fasted glucose. In multivariable-adjusted logistic regression analysis, sex-specifically dichotomized baseline uric acid (<5.1 and <4.1 mg/dL vs. higher values) significantly predicted the non-fatal events in the whole sample (relative risk (RR) 1.51 [95% confidence interval (CI) 1.02; 2.26]), as well as in men, while composite endpoint in the whole sample tended to rise (RR 1.38). Compared with the intermediate one, the top and bottom SUA tertiles combined tended to confer mortality risk (RR 2.40 [95% CI 0.89; 6.51]). Adverse outcomes in diabetic women were predicted by tertiles 2 and 3. Conclusions: Inverse association of SUA with adverse outcomes, especially in men, is consistent with the involvement of uric acid mass in autoimmune activation. The positive association of uric acid with adverse outcomes in diabetic women is likely mediated by concomitant high-density lipoprotein dysfunction.

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