scholarly journals Assessment of sodium thiosulfate neutralizing effect on micro-hardness of dentin treated with sodium hypochlorite

2020 ◽  
Author(s):  
Safoora Sahebi ◽  
fereshteh Sobhnamayan ◽  
Fariborz Moazami ◽  
Mohammadhasan Naseri
Keyword(s):  
Adverse Effect ◽  
Sodium Hypochlorite ◽  
Normal Saline ◽  
Sodium Thiosulfate ◽  
Measured Data ◽  
Control Group ◽  
P Value ◽  
Pairwise Comparisons ◽  
Micro Hardness ◽  
Neutralizing Agent

Abstract Background: This study aims to evaluate the ability of sodium thiosulfate (STS) to neutralize the adverse effect of sodium hypochlorite (NaOCl) on dentin micro-hardness.Methods: Fifty single-rooted teeth were longitudinally sectioned. The samples divided into a control and four sample groups (n = 20). All the samples were immersed in different solutions as follows, Control: Normal saline for 15 min, G1and G2: 2.5% NaOCl for 15 min, G3: 2.5% NaOCl for 15 min, followed by 5% STS for 10 min, G4: Normal saline for 15 min followed by 5% STS for 10 min. All groups except G1 incubated for one week before the test. The micro-hardness of samples was measured. Data were analyzed using the Kruskal-Wallis test for pairwise comparisons. A p-value < 0.05 was considered significant. Results: All groups showed a significant decrease in the micro-hardness value compared with the control group. NaOCl for one week (G2) reduced the micro-hardness of dentine compared with samples, tested immediately after immersion in NaOCl (G1) (p < 0.05). NaOCl alone (G2) or treated with STS (G3) resulted in a significant decrease in micro-hardness compared with the STS group (G4) (p < 0.05).Conclusions: STS as a neutralizing agent could not prevent the dentin micro-hardness downturn caused by NaOCl.

scholarly journals Assessment of sodium thiosulfate neutralizing effect on micro-hardness of dentin treated with sodium hypochlorite

2020 ◽  
Author(s):  
Safoora Sahebi ◽  
Fereshteh Sobhnamayan ◽  
Fariborz Moazami ◽  
Mohammadhasan Naseri
Keyword(s):  
Adverse Effect ◽  
Sodium Hypochlorite ◽  
Normal Saline ◽  
Sodium Thiosulfate ◽  
Measured Data ◽  
Control Group ◽  
P Value ◽  
Pairwise Comparisons ◽  
Micro Hardness ◽  
Neutralizing Agent

Abstract Background: This study aims to evaluate the ability of sodium thiosulfate (STS) to neutralize the adverse effect of sodium hypochlorite (NaOCl) on dentin micro-hardness.Methods: Fifty single-rooted teeth were longitudinally sectioned. The samples divided into a control and four sample groups (n = 20). All the samples were immersed in different solutions as follows, Control: Normal saline for 15 min, G1and G2: 2.5% NaOCl for 15 min, G3: 2.5% NaOCl for 15 min, followed by 5% STS for 10 min, G4: Normal saline for 15 min followed by 5% STS for 10 min. All groups except G1 incubated for one week before the test. The micro-hardness of samples was measured. Data were analyzed using the Kruskal-Wallis test for pairwise comparisons. A p-value < 0.05 was considered significant.Results: All groups showed a significant decrease in the micro-hardness value compared with the control group. NaOCl for one week (G2) reduced the micro-hardness of dentine compared with samples, tested immediately after immersion in NaOCl (G1) (p < 0.05). NaOCl alone (G2) or treated with STS (G3) resulted in a significant decrease in micro-hardness compared with the STS group (G4) (p < 0.05). Conclusions: STS as a neutralizing agent could not prevent the dentin micro-hardness downturn caused by NaOCl.

scholarly journals Assessment of sodium thiosulfate neutralizing effect on micro-hardness of dentin treated with sodium hypochlorite

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Safoora Sahebi ◽  
Fereshteh Sobhnamayan ◽  
Fariborz Moazami ◽  
Mohammadhasan Naseri
Keyword(s):  
Adverse Effect ◽  
Sodium Hypochlorite ◽  
Normal Saline ◽  
Sodium Thiosulfate ◽  
Measured Data ◽  
Control Group ◽  
Pairwise Comparisons ◽  
Micro Hardness ◽  
Neutralizing Agent

Abstract Background This study aims to evaluate the ability of sodium thiosulfate (STS) to neutralize the adverse effect of sodium hypochlorite (NaOCl) on dentin micro-hardness. Methods Fifty single-rooted teeth were longitudinally sectioned. The samples divided into a control and four sample groups (n = 20). All the samples were immersed in different solutions as follows, Control: Normal saline for 15 min, G1and G2: 2.5% NaOCl for 15 min, G3: 2.5% NaOCl for 15 min, followed by 5% STS for 10 min, G4: Normal saline for 15 min followed by 5% STS for 10 min. All groups except G1 incubated for one week before the test. The micro-hardness of samples was measured. Data were analyzed using the Kruskal–Wallis test for pairwise comparisons. A p value < 0.05 was considered significant. Results All groups showed a significant decrease in the micro-hardness value compared with the control group. NaOCl for one week (G2) reduced the micro-hardness of dentine compared with samples, tested immediately after immersion in NaOCl (G1) (p < 0.05). NaOCl alone (G2) or treated with STS (G3) resulted in a significant decrease in micro-hardness compared with the STS group (G4) (p < 0.05). Conclusions STS as a neutralizing agent could not prevent the dentin micro-hardness downturn caused by NaOCl.

scholarly journals Assessment of Sodium Thiosulfate Neutralizing Effect on Micro-hardness of Dentin Treated With Sodium Hypochlorite

2020 ◽  
Author(s):  
Safoora Sahebi ◽  
fereshteh Sobhnamayan ◽  
Mohammadhasan Naseri ◽  
Fariborz Moazami
Keyword(s):  
Sodium Hypochlorite ◽  
Normal Saline ◽  
Sodium Thiosulfate ◽  
Hardness Test ◽  
Control Group ◽  
P Value ◽  
Pairwise Comparisons ◽  
Micro Hardness ◽  
Neutralizing Agent ◽  
Vickers Micro Hardness

Abstract Background The aim of this study is to evaluate the ability of sodium thiosulfate (STS) to reverse the adverse effect of sodium hypochlorite (NaOCl) on dentin microhardness. Methods Fifty single-rooted teeth were decoronated and longitudinally sectioned. The samples were divided into a control and four sample groups (n = 20): Normal saline for 15 min as the control group, G1: 2.5% NaOCl for 15 min without an incubation period, G2: 2.5% NaOCl for 15 min, G3: 2.5% NaOCl for 15 min irrigated with normal saline followed by 5% Na2S2O3 for 10 min, G4: Normal saline for 15 min followed by 5% Na2S2O3 for 10 min. All groups except G1 were incubated for 1 week. The microhardness measurements were determined using the Vickers micro-hardness test. Data were analyzed using the Kruskal-Wallis test for pairwise comparisons. A p-value < 0.05 was considered significant. Results All groups showed a significant decrease in the micro-hardness value compared with the control group. NaOCl for 1 week (G2) reduced the micro-hardness of dentine compared with samples, tested immediately after immersion in NaOCl (G1) (p < 0.05). NaOCl alone (G2) or treated with Na2S2O3 (G3) resulted in a significant decrease in microhardness compared with the Na2S2O3 group (G4) (p < 0.05). Conclusions Sodium thiosulfate as a neutralizing agent could not prevent the microhardness downturn caused by sodium hypochlorite

scholarly journals Effect of Application Time of Two Different Disinfectants on the Surface Roughness of an Elastomeric Impression Material

2020 ◽  
Author(s):  
Tahir Karaman ◽  
Faruk Oztekin ◽  
Samet Tekin
Keyword(s):  
Surface Roughness ◽  
Sodium Hypochlorite ◽  
Quaternary Ammonium ◽  
Rank Test ◽  
Control Group ◽  
P Value ◽  
Sodium Hypochlorite Solution ◽  
Application Time ◽  
Impression Material ◽  
Significant Difference

Introduction: Pathogens, such as cytomegalovirus, hepatitis B virus, hepatitis C virus, herpes simplex virus types 1 and 2, and human immunodeficiency virus are transmitted, threatening the health of dental laboratory workers, especially as a result of saliva and blood contact of patients. To prevent cross-infection, impression materials should be disinfected at the end of the impression process in the mouth. Aim: To study the effect of application time of sodium hypochlorite and quaternary ammonium-based disinfectant solution on the surface roughness of an elastomeric impression material. Materials and Methods: In this in-vitro study done during March 2020, 10 disc-shaped samples were used in each group, with a total of 110 samples obtained from a light body elastomeric impression material with dimensions of 15×3 mm. The samples were kept in a sodium hypochlorite solution (Wizard; Rehber Kimya, Istanbul, Turkey) at concentrations of 1% and 5% for 1, 5, 10, and 30 minutes and in a quaternary ammonium-based disinfectant (Zeta 7 Solution, Zhermack SpA, Italy) for 10 and 30 minutes. Surface roughness measurements were taken with a profilometer device. The data obtained were statistically analysed by Kolmogorov-Smirnov test and Wilcoxon signed rank test for dependent/paired groups for the continuous data. The significance level was set to α=0.05. Results: A statistically significant difference was found between the control group and the 1% sodium hypochlorite (30 min p-value 0.037), and 5% sodium hypochlorite (30 min p-value 0.017). The statistical evaluation of the surface roughness of the samples with different concentrations of sodium hypochlorite and the same times was done and found statistically significant at 30 mins, p-value 0.021. Conclusion: The prolonged application of the sodium hypochlorite disinfectant at 1% and 5% concentrations caused a significant increase in the light body elastomeric impression material’s surface roughness

scholarly journals The effect of Curcuminvs. Curcumin combined Antibiotic Ointmentson the Healing of skin wound

2021 ◽  
Vol 14 (3) ◽  
pp. 1587-1593
Author(s):  
Emad K. Abbas ◽  
Hussein H. Echrish ◽  
Sabaa A. Mohammed
Keyword(s):  
Wound Healing ◽  
Normal Saline ◽  
Biological Effects ◽  
Skin Wound ◽  
Control Group ◽  
P Value ◽  
Average Weight ◽  
Wide Range ◽  
Significant Difference ◽  
Animal House

Background:Turmeric is typically used as a spicy food preservative and colorant. It has been proved that curcumin has a wide range of biological effects including anti-inflammatory, anti-viral, anti-fungal, and curcumin activity that can improve antibiotic activity on the wounds. Objectives: To evaluate the effects of Curcumin with and without antibiotics on skin wound treatment. Materials and Methods: The protocol was approved by the animal house in medical college / Basra university. This study used nine male rabbits aged about 6 months and an average weight of (1.083 g). Each group consists of 3 rabbits: control group (normal saline) A, topical curcumin in group B, topical curcumin, and tetracycline ointment in group C. Regular treatments were given to rabbits in therapeutic groups. Result: The lowest Mean ± SDof swelling of suturing area was noted in both groups that treated by curcumin alone (9.07 ± 0.97 vs 15±1 mm, p value = 0.002) and that treated with curcumine and antibiotic (9.1±0.9vs 15±1 mm, p value = 0.002) versus the control group ( that treated by normal saline) and the lowest Mean ± SD of elevation of suture line was noted in both group that treated by curcumin alone (2.63 ± 0.06 vs 4.07±0.21 mm, p value >0.001) and that treated with curcumin and antibiotic (2.7 ± 0.2 vs 4.07±0.21 mm, p value =0.001) versus control group. There is no significant statistical difference between the Mean ± SD neither of swelling of suture area nor of elevation of suture lines of groups that treated by curcumin alone and group that treated with curcumin and antibiotic [(9.07 ± 0.97 vs 9.1 ±0.9, p value=0.97),(2.63±0.06 vs 2.7 ± 0.2, p value=0.61) respectively]. The histopathological evaluation is consistent with morphological changes as at day 3 of wound healing in both groups that treated by curcumine with and without antibiotic, there is formation a thin layer of keratin and absence of features that indicate delay wound healing such as hemorrhage, inflammatory cell infiltrate of (Neutrophils, macrophages and lymphocytes) and debris, which are detected in control group. Furthermore, at day 7 of control group, there is decrease of inflammation, presence of gap between the two edgesof the wound but no keratin formation. No clear histopathological difference in wound healing between tested groups that treated by curcumin with and without antibiotic. Conclusion: There issignificant clinical and histological evidences that the curcumin not only prevent delay of wound healing but it is also enhanced wound healing. No significant difference in using curcumin alone or combine it with local antibiotic.

scholarly journals Effectiveness of periurethral cleaning solution to bacteria colonization count at periurethral area prior to urinary catheterization.

2016 ◽  
Vol 1 (1) ◽  
pp. 66
Author(s):  
Kristina Lisum ◽  
Ni Luh Widani
Keyword(s):  
Patient Safety ◽  
Normal Saline ◽  
Povidone Iodine ◽  
Control Group ◽  
P Value ◽  
Regression Result ◽  
Post Intervention ◽  
Cleaning Solution ◽  
Quasi Experimental ◽  
Reducing Bacteria

<div align='justify> Introduction :Patient safety is an important element that must be notice when providing care to patients, including nurse. The incidence of catheterized patient increasingly 25 % from total patients that hospitalized can lead urinary tract infection.  The purpose of this study was to compare the effectiveness of cleaning periurethral with povidone iodine 10 %, povidone iodine 2 % and normal saline to bacteria colonization prior to catetherization. Methods : This study used quasi-experimental, pre and post intervention design with control group.  Result : Periurethral swabs were obtained from a total 60 patients ( povidone iodine 10 % as control group , 20;  povidone iodine 2 %, 20; normal saline, 20).  Through paired t-test ,there  was significant decreased  (p value : .00; p < .05) in bacteria colonization count  using povidone iodine 2% and normal saline ; using  povidone iodine  10 %  , there was no significant decreased (p value : .55; p >.05) in bacteria colonization count. While, a simple linear regression result that povidone iodine 2% is the most effective solution on reducing bacteria colonization in periurethral area rather than other solution. In addition, recommendation needed to test bacteria colonization in urine culture using those periuretral cleaning solutions. Keyword: periurethral cleaning, patient safety, povidone iodine 2%, povidone iodine 10%, normal saline

Deproteinizing Agents as an Effective Enamel Bond Enhancer-An in Vitro Study

2017 ◽  
Vol 41 (4) ◽  
pp. 280-283 ◽  
Author(s):  
Pallavi Hasija ◽  
Vinod Sachdev ◽  
Shivani Mathur ◽  
Rishi Rath
Keyword(s):  
Bond Strength ◽  
Sodium Hypochlorite ◽  
Shear Bond Strength ◽  
Testing Machine ◽  
Acid Etching ◽  
Control Group ◽  
P Value ◽  
Group 4 ◽  
Significant Difference ◽  
Group 1

Objective: The aim of this study was to compare the effect of different deproteinizing agents on shear bond strength of composite to primary teeth enamel. Study Design: Forty sound primary molars divided in 4 groups of 10 teeth each. In control group 1, enamel was etched for 60 seconds with 37% phosphoric acid and rinsed with water. Group 2: after acid etching deproteinizing agent 5 % sodium hypochlorite was applied for 60 seconds and rinsed. Group 3: after acid etching deproteinizing agent papain gel was applied for 60 seconds and rinsed. Group 4: after acid etching deproteinizing agent bromelain gel applied for 60 seconds and rinsed. Following this, bonding agent was applied to treated enamel surface and composite resin disc were build. Samples were then tested for shear bond strength using Universal Testing Machine. Results: Mean SBS was highest for group 4 and lowest for group 1. No statistically significant difference (p value &gt;0.05) was found between all the four groups. Conclusion: Among deproteinizing agents, deproteinization when carried out with bromelain gel and sodium hypochlorite showed effective bond strength as compared to papain.

scholarly journals Evaluation of Post-Operative Analgesia Using Clonidine as an Adjuvant with Caudal Bupivacaine in Paediatric Patients Posted for Infraumbilical Surgery

2021 ◽  
Vol 10 (35) ◽  
pp. 3005-3011
Author(s):  
Sinjini Agarwal ◽  
Neeta Chaudhari Verma ◽  
Amol P.S. ◽  
Pyarelal Pyarelal ◽  
Suzanna Elsa Varghese ◽  
...  
Keyword(s):  
Normal Saline ◽  
Ethical Review ◽  
Control Group ◽  
P Value ◽  
Paediatric Surgery ◽  
Rescue Analgesia ◽  
Significant Group ◽  
Number Of Patients ◽  
Group B ◽  
Caudal Epidural

BACKGROUND Caudal epidural block is a highly popular method of administering analgesia to children undergoing infraumbilical surgeries. Addition of clonidine, a centrally acting alpha 2 agonist as an adjuvant to caudal bupivacaine has added advantages of providing prolonged post-operative analgesia and also, thus reducing the number of doses of post-operative rescue analgesics. In this study, we wanted to compare the efficacy and safety of caudally administered clonidine as an adjuvant to bupivacaine. METHODS This was a prospective, comparative interventional study and was conducted in the Department of Anaesthesia at JNMC, Sawangi (Meghe) Wardha in accordance with the guidelines and permission of the institutional ethical review board. The study was carried out with 40 patients in each group randomly allocated using computer generated software, posted for infraumbilical surgeries between the age group 2 years to 7 years, American Society of Anaesthesiologists (ASA) grade I and II. Group B (control group) – Caudal epidural with 0.25 % bupivacaine 1 ml/kg + 1 ml normal saline. Group C (study group)- Caudal epidural with 0.25 % bupivacaine 1 ml/kg with clonidine 1 microgram/kg + 1 ml normal saline. RESULTS In our study, the mean duration of analgesia i.e. mean time for requirement of first rescue analgesia in group C was 9.9 ± 1.4 hours as compared to 4.7 ± 1.4 hours in group B (P < 0.0001). In this study, we used FLACC (face, legs, activity, cry, consolability) pain scale with its 0 - 10 score range for assessing the pain intensity. At FLACC pain score 4 or more, first dose of rescue analgesic was given. This score was reached at 8.8 hours in Group C (mean FLACC score at 3.8 ± 0.7) and 3.6 hours in Group B (mean FLACC score 3.4 ± 0.9) with P value (= 0.014) (significant). Group C required significantly lesser number of rescue analgesics in comparison to Group B. The number of doses of rescue analgesics required in the Group B were definitely more than that in Group C wherein 62.5 % required 3 doses and 25 % required 4 doses of rescue analgesics. On the other hand, in Group C the number of patients requiring more than 2 doses of rescue analgesia was 0 % thus proving the efficacy of clonidine in prolonging post-operative analgesia. CONCLUSIONS We concluded that caudally administered clonidine, in a dose of 1 microgram/kg as an adjuvant to 0.25 % bupivacaine 1 ml/kg, proved to be efficacious in providing prolonged analgesia both intraoperatively and post-operatively. Also, we observed that this addition, reduced the requirement of post-operative rescue analgesia and its associated side effects. KEY WORDS Caudal Epidural, Infraumbilical Paediatric Surgery, Clonidine, Bupivacaine, Postoperative Analgesia

scholarly journals STUDY OF EFFECT OF INTERMITTENT EPIDURAL INJECTION OF NORMAL SALINE ON DURATION OF MOTOR AND SENSORY BLOCKADE AFTER COMBINED SPINAL EPIDURAL (CSE) ANAESTHESIA. A PROSPECTIVE, RCT

2019 ◽  
pp. 1-4
Author(s):  
Deepak Bharat Kawade
Keyword(s):  
Epidural Catheter ◽  
Normal Saline ◽  
Epidural Anaesthesia ◽  
Intervention Group ◽  
Motor Recovery ◽  
Control Group ◽  
P Value ◽  
Motor Blockade ◽  
Sensory Blockade ◽  
Spinal Epidural

BACKGROUND: Prolonged motor and sensory block following Central Neuraxial Blockade (CNB) is associated with extended postoperative immobilization and its complications. Speedy recovery from motor blockade would improve the patients' acceptance of neuraxial anesthesia. Previous studies in patients undergoing epidural anaesthesia, demonstrated rapid motor recovery after administration of epidural crystalloids. We studied the effect of intermittent bolus injection of Normal saline (NS) on the duration of sensory and motor recovery after Combined spinal epidural anaesthesia (CSEA). METHODS:60 patients (ASA I-III) scheduled for surgeries under CSEA lasting for 1½ to 2 hrs were divided equally by systematic random sampling at the end of surgery. Control group - No bolus of NS flush was given through the epidural catheter. Intervention group -15 ml of NS flush through epidural catheter was given thrice. Sensory level, Motor blockade and vitals were noted at 5 min interval for 2 hours from end of surgery. RESULTS: 1. Sensory levels in two groups were significantly different (p-value < 0.001) at the end of two hours. In intervention group, T8 level was predominant, while in control group L1 level was predominant. 2. Difference in motor block in two groups was significant as (p-value < 0.001). In intervention group, 86.67% had Bromage score 0, while in control group 80% had score 1 at the end of 2 hrs. Conclusion: Postoperative epidural flush with 45 ml Normal saline hastened the motor recovery following CSEA without shortening of the duration of sensory blockade

scholarly journals Antibacterial Effects of a 940 nm Diode Laser With/ Without Silver Nanoparticles Against Enterococcus faecalis

2021 ◽  
Vol 12 (1) ◽  
pp. e73-e73
Author(s):  
Seyedeh Sareh Hendi ◽  
Maryam Shiri ◽  
Banafsheh Poormoradi ◽  
Mohammad Yousef Alikhani ◽  
Saeid Afshar ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Diode Laser ◽  
Sodium Hypochlorite ◽  
Negative Control Group ◽  
Negative Control ◽  
Control Group ◽  
P Value ◽  
Antibacterial Effects ◽  
Group 4 ◽  
Group 1

Introduction: The final goal of root canal therapy is to remove of the most bacteria from the root canal. This study aimed at comparing the antibacterial effects of a diode laser with a wavelength of 940nm and silver nanoparticles and the synergic effects of both techniques on Enterococcus faecalis. Methods: Ninety single-rooted human teeth were decoronated and prepared with rotary files. The samples were irrigated with sodium hypochlorite and EDTA17%. Then they were autoclaved and contaminated with E. faecalis suspension (1.5 × 108 CFU/mL) for 21 days. The samples were fixed in a microtube and were randomly divided into 4 experimental (n=20) groups and a negative control group (n=10) as follows: Group 1: hypochlorite sodium 5%, Group 2: silver nanoparticle, Group 3: diode laser, and Group 4: diode laser and silver nanoparticle. The samples were obtained from dentin chips before and after the intervention. The data were analysed using the Kruskal-Wallis nonparametric test. Furthermore, alterations in bacterial colonies were entered using the Wilcoxon signed ranks test (α=0.05). Results: There was a significant decrease in colony counts for all groups after interventions (P value<0.05). Also, all groups showed more reductions in colony counts compared with the negative control group (P value <0.004). There was a significant reduction for group 1 in comparison with other groups (P value <0.001) and this group had an extreme decrease of colony counts (RCC=100%). There was an important differential between silver nanoparticles and diode laser groups in bacterial counts (P value<0.001) and silver nanoparticles (RCC=83.15%) had more efficiency than the diode laser (RCC=41/33%). RCC of group 4 was 68/52%. Conclusion: Followed by sodium hypochlorite 5%, silver nanoparticles were the most effective antibacterial substances. The 940 nm laser diode had less antibacterial effect compared to its use with silver nanoparticles.

Sign in / Sign up

Export Citation Format

Share Document