scholarly journals Telemedicine application in patient with Diabetes, Hypertension and Rheumatoid arthritis: A systematic review and meta-analysis

2021 ◽  
Author(s):  
Yue Ma ◽  
Yan Zhao ◽  
Chongbo Zhao ◽  
Jiahong Lu ◽  
Hong Jiang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systematic Review ◽  
Blood Pressure ◽  
Chronic Disease ◽  
Quality Assessment ◽  
Meta Analysis ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Term Care ◽  
Significant Difference

Abstract Background: Under the global epidemic condition，the telemedicine was widely used in the world, especially in the period of long-term care and treatment. The aim of study is to verify the effectiveness of telemedicine in the management of chronic disease by using scientific methods such as hypertension, diabetes, rheumatoid arthritis by using Meta-analysis and systematic review methods. The purpose of this study was to systematic review of the effect of telemedicine in chronic disease, so as to provide inspiration for chronic disease management in the future.Methods: Article searching were performed using Web of Science, PubMed, MEDLINE, EMBASE and other library or database to retrieve articles which published from database and library establishment to October 31st, 2020. Literature quality assessment, systematic review and Meta-analysis were then performed.Results: 12 articles were included in the literature quality assessment (7 diabetes,3 hypertensions,2 rheumatoid arthritis), the article included in this study is of high quality. There are 7 articles included in the Meta-analysis, the result shows there have effect in glycosylated hemoglobin after 12 months of intervention (95%CI=-1.53, -0.16; Z=2.42; P=0.02), compare with 6 months (95%CI=-1.32, -0.01; Z=1.99; P=0.05). It also showed that there was no significant difference in fasting blood glucose after 6 months of intervention (95%CI=-1.19,0.21; Z=1.37; P=0.17). Both systolic blood pressure (95%CI=-12.79, -3.69; Z=3.55; P= 0.0004) and diastolic blood pressure (95%CI=-9.90, -0.43; Z=2.14; P= 0.03) showed statistically significant. Moreover, we also found positive influence of telemedicine about good behaviors and rehabilitation for rheumatoid arthritis patients.Conclusion: The results showed that telemedicine had a positive effect on the management of diabetes, hypertension and rheumatoid arthritis, especially on the management of glycosylated hemoglobin and blood pressure. Telemedicine technologies have great promotion to access the medical services and improve the quality of care, especially for people with chronic diseases.

scholarly journals Telemedicine application in patient with Diabetes, Hypertension and Rheumatoid arthritis：A systematic review and meta-analysis

2021 ◽  
Author(s):  
Yue Ma ◽  
Yan Zhao ◽  
Chongbo Zhao ◽  
Jiahong Lu ◽  
Hong Jiang ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systematic Review ◽  
Blood Pressure ◽  
Chronic Disease ◽  
Quality Assessment ◽  
Meta Analysis ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Term Care ◽  
Significant Difference

Abstract Background: Under the global epidemic condition，the telemedicine was widely used in the world, especially in the period of long-term care and treatment. The aim of study is to verify the effectiveness of telemedicine in the management of chronic disease by using scientific methods such as hypertension, diabetes, rheumatoid arthritis by using Meta-analysis and systematic review methods. The purpose of this study was to systematic review of the effect of telemedicine in chronic disease, so as to provide inspiration for chronic disease management in the future.Methods: Article searching were performed using Web of Science, PubMed, MEDLINE, EMBASE and other library or database to retrieve articles which published from database and library establishment to October 31st, 2020. Literature quality assessment, systematic review and Meta-analysis were then performed.Results: 12 articles were included in the literature quality assessment (7 diabetes,3 hypertensions,2 rheumatoid arthritis), the article included in this study is of high quality. There are 7 articles included in the Meta-analysis, the result shows there have effect in glycosylated hemoglobin after 12 months of intervention (95%CI=-1.53, -0.16; Z=2.42; P=0.02), compare with 6 months (95%CI=-1.32, -0.01; Z=1.99; P=0.05). It also showed that there was no significant difference in fasting blood glucose after 6 months of intervention (95%CI=-1.19,0.21; Z=1.37; P=0.17). Both systolic blood pressure (95%CI=-12.79, -3.69; Z=3.55; P= 0.0004) and diastolic blood pressure (95%CI=-9.90, -0.43; Z=2.14; P= 0.03) showed statistically significant. Moreover, we also found positive influence of telemedicine about good behaviors and rehabilitation for rheumatoid arthritis patients.Conclusion: The results showed that telemedicine had a positive effect on the management of diabetes, hypertension and rheumatoid arthritis, especially on the management of glycosylated hemoglobin and blood pressure. Telemedicine technologies have great promotion to access the medical services and improve the quality of care, especially for people with chronic diseases.

scholarly journals The Effects of Curcuma longa in Insulin Resistance

2020 ◽  
pp. 86-98
Author(s):  
Laís Maria Pescinini Salzedas ◽  
Giullia Trevisan Covre Simão Batista ◽  
Sandra Maria Barbalho
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Serum Lipids ◽  
Randomized Clinical Trials ◽  
Plasma Lipids ◽  
Curcuma Longa ◽  
Meta Analysis ◽  
Glycosylated Hemoglobin ◽  
Fasting Blood Glucose ◽  
Liver Transaminases

Background: Curcumin is seen as an anti-hyperglycemic agent that acts by improving the expression of glucose transporters. It is also related to the reduction of glycosylated hemoglobin, improvement of insulin sensitivity, plasma lipids, and blood pressure. Aim: The purpose of this article is to review the effects of Curcuma longa in insulin resistance. Methodology: PUBMED and EMBASE databases were searched, and PRISMA (Preferred Reporting Items for a Systematic Review and Meta-analysis) guidelines were followed to build the review. Results: Nineteen Randomized Clinical Trials (RCTs) met the inclusion criteria and were described according to PICO (Population, Intervention, Comparison, and Outcomes). Conclusion: Curcumin could be considered in the therapeutic approach of patients with Insulin Resistance, once it is related to the reduction of oxidative stress, inflammation, serum fasting blood glucose, HOMA-IR, blood pressure, serum lipids, and liver transaminases. However, the results depend on the dose, intervention time, and formulation of the compound.Insulin resistance

scholarly journals Effect of Curcumin on Diabetic Kidney Disease: A Systematic Review and Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Clinical Trials

2021 ◽  
Vol 2021 ◽  
pp. 1-14
Author(s):  
Zhao Jie ◽  
Mo Chao ◽  
Ai Jun ◽  
Shi Wei ◽  
Meng LiFeng
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Kidney Disease ◽  
Diabetic Kidney Disease ◽  
Meta Analysis ◽  
Fasting Blood Glucose ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Cochrane Library ◽  
Diabetic Kidney

Background. Curcumin, a polyphenolic constituent from Curcuma longa, possesses antioxidant, hypolipidemic, and antidiabetic properties and has been reported to protect against diabetic kidney disease (DKD); however, the effect is inconsistent. Objective. This systematic review and meta-analysis aimed to investigate the effect of curcumin supplementation on renal function, lipid profile, blood pressure, and glycemic control in DKD. Methods. A systematic and comprehensive literature search of interrelated randomized controlled trials (RCTs) was conducted in PubMed, Embase, Cochrane Library, Web of Science, Scopus, and ClinicalTrials.gov from inception to July 30, 2021. Two investigators independently extracted data and assessed the risk of bias. Weighted mean differences (WMDs) with 95% confidence intervals (CIs) were calculated to describe the effect sizes using a fixed-effect model. Statistical analysis was performed using STATA 14.0 and RevMan 5.3. Results. Five RCTs involving 290 participants with DKD were included. Curcumin supplementation significantly improved the serum creatinine (WMD: −0.16 mg/dL, 95% CI: −0.3 to −0.02, P  = 0.029, I2 = 0%, moderate certainty), total cholesterol (WMD: −10.13 mg/dL, 95% CI: −17.84 to −2.14, P  = 0.01, I2 = 0%, moderate certainty), systolic blood pressure (WMD: 3.94 mmHg, 95% CI: 1.86 to 6.01, P  < 0.01, I2 = 33.5%, moderate certainty), and fasting blood glucose (WMD: −8.29 mg/dL, 95% CI: −15.19 to −1.39, P  = 0.019, I2 = 43.7%, moderate certainty) levels; however, it had no significant effects on blood urea nitrogen, proteinuria, triglyceride, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, and diastolic blood pressure levels. Conclusions. Curcumin may provide great potential effects against DKD. More large-scale and high-quality RCTs are required to confirm these findings.

scholarly journals Prevalence of Headache in Patients With Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-Analysis of 14,275 Patients

2020 ◽  
Vol 11 ◽  
Author(s):  
Md Asiful Islam ◽  
Sayeda Sadia Alam ◽  
Shoumik Kundu ◽  
Tareq Hossan ◽  
Mohammad Amjad Kamal ◽  
...  
Keyword(s):  
Systematic Review ◽  
Quality Assessment ◽  
Confidence Intervals ◽  
Random Effects ◽  
Critical Appraisal ◽  
Meta Analysis ◽  
Clinical Manifestations ◽  
Random Effects Model ◽  
Pooled Prevalence ◽  
Significant Difference

Background: Coronavirus disease 2019 (COVID-19) started to spread globally since December 2019 from Wuhan, China. Headache has been observed as one of the clinical manifestations in COVID-19 patients. We aimed to conduct a comprehensive systematic review and meta-analysis to estimate the overall pooled prevalence of headache in COVID-19 patients.Methods: PubMed, Scopus, ScienceDirect, and Google Scholar databases were searched to identify studies published between December 2019 and March 2020. Adult (≥18 years) COVID-19 patients were considered eligible. We used random-effects model to estimate the pooled prevalence with 95% confidence intervals (CIs). Quality assessment was done using the Joanna Briggs Institute critical appraisal tools. This study is registered with PROSPERO (CRD42020182529).Results: We identified 2,055 studies, of which 86 studies (n = 14,275, 49.4% female) were included in the meta-analysis. Overall, the pooled prevalence of headache in COVID-19 patients was 10.1% [95% CI: 8.76–11.49]. There was no significant difference of headache prevalence in severe or critical vs. non-severe (RR: 1.05, p = 0.78), survived (recovered or discharged) vs. non-survived (RR: 1.36, p = 0.23), and ICU vs. non-ICU (RR: 1.06, p = 0.87) COVID-19 patients. We detected 64.0, 34.9, and 1.1% of the included studies as high, moderate, and low quality, respectively.Conclusions: From the first 4-month data of the outbreak, headache was detected in 10.1% of the adult COVID-19 patients.

scholarly journals Demographic and socioeconomic inequalities in ideal cardiovascular health: A systematic review and meta-analysis

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255959
Author(s):  
Janko Janković ◽  
Stefan Mandić-Rajčević ◽  
Maša Davidović ◽  
Slavenka Janković
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Cardiovascular Health ◽  
Meta Analysis ◽  
Fasting Blood Glucose ◽  
Random Effect ◽  
Heart Association ◽  
Ideal Cardiovascular Health ◽  
Low Prevalence ◽  
The Relationship

Background In 2010, the American Heart Association introduced a new concept of ideal cardiovascular health (CVH) defined as the simultaneous presence of 7 favorable CVH metrics (smoking, diet, physical activity, body mass index, blood pressure, total cholesterol, and fasting blood glucose). The objective of this study was to conduct a systematic literature review and meta-analysis of studies examining the prevalence of ideal CVH, and each of the ideal CVH metrics as well as the relationship between socio-demographic determinants and ideal CVH. Methods A comprehensive literature search was conducted in Medline and Scopus databases for studies published between 1 January 2010 and 30 June 2020. A total of 50 studies including 2,148,470 participants were analyzed. Associations were estimated using DerSimonian-Laird random-effect models. Heterogeneity was investigated through subgroup analyses, Q-test, and I2 statistics. Results This study showed a low prevalence of ideal CVH defining as 6 and 7 ideal metrics (3.3%). Among seven ideal CVH metrics, smoking was the best metric (71%), while the poorest CVH metric was a healthy diet (5.8%). Gender was a statistically significant moderator of ideal smoking (81% in females and 60% in males) and ideal blood pressure (42% in females and 30% in males). Females and young adults had better CVH status compared to males and older adults. Also, more educated and better-off individuals had a greater number of ideal CVH metrics. Conclusions To the best of our knowledge, this is the first systematic review on the relationship between participants’ socioeconomic status and ideal CVH. The results suggest that the prevalence of ideal CVH and most metrics was unsatisfactory. In order to achieve the improvement of the CVH metrics and the overall ideal CVH, nationwide prevention efforts at the population and individual levels are urgently needed.

A systematic review and meta-analysis of infection risk with small molecule JAK inhibitors in rheumatoid arthritis

Rheumatology ◽  
2019 ◽  
Vol 58 (10) ◽  
pp. 1755-1766 ◽  
Author(s):  
Katie Bechman ◽  
Sujith Subesinghe ◽  
Sam Norton ◽  
Fabiola Atzeni ◽  
Massimo Galli ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Systematic Review ◽  
Opportunistic Infections ◽  
Meta Analysis ◽  
Incidence Rates ◽  
Jak Inhibitors ◽  
Significant Difference ◽  
Registration Number ◽  
Rate Ratios ◽  
Phase Ii And Iii

Abstract Objectives To evaluate the risk of serious infection (SI) and herpes zoster (HZ) in rheumatoid arthritis patients receiving JAK inhibitors. Methods We conducted a systematic literature review and meta-analysis of phase II and III randomized controlled trials of tofacitinib (5 mg bid), baricitinib (4 mg od) and upadacitinib (15 mg od). Patient-exposure years were calculated. A per-protocol analysis was applied, incorporating follow-up time from patients randomized to placebo who cross into the treatment arm. Pooled incidence rates per 100 person-years of SI and HZ were calculated. Incidence rate ratios (IRRs) of drug vs placebo were compared using a meta-synthesis approach. Results Twenty-one studies were included in the meta-analysis; 11 tofacitinib (5888 patients), six baricitinib (3520 patients) and four upadacitinib studies (1736 patients). For SI, the incidence rates were 1.97 (95% CI: 1.41, 2.68), 3.16 (95% CI: 2.07, 4.63) and 3.02 (95% CI: 0.98, 7.04), respectively. The IRRs comparing treatment arm to placebo were statistically non-significant: 1.22 (95% CI: 0.60, 2.45), 0.80 (95% CI: 0.46, 1.38) and 1.14 (95% CI: 0.24, 5.43), respectively. For HZ, the incidence rates were 2.51 (95% CI: 1.87, 3.30), 3.16 (95% CI: 2.07, 4.63) and 2.41 (95% CI: 0.66, 6.18), respectively. The IRR of HZ comparing baricitinib with placebo was 2.86 (95% CI: 1.26, 6.50). Non-significant IRRs were seen with tofacitinib and upadacitinib: 1.38 (95% CI: 0.66, 2.88) and 0.78 (95% CI: 0.19, 3.22), respectively. Indicator opportunistic infections excluding HZ were too rare to provide meaningful incidence rates. Conclusion The absolute SI rates were low. However across the JAK inhibitors, the incidence of HZ is higher than expected for the population (3.23 per 100 patient-years). While the risk was numerically greatest with baricitinib, indirect comparisons between the drugs did not demonstrate any significant difference in risk. Systematic review registration number Prospero 2017 CRD4201707879.

scholarly journals Effects of Caffeinated and Decaffeinated Coffee Consumption on Metabolic Syndrome Parameters: A Systematic Review and Meta-Analysis of Data from Randomised Controlled Trials

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 957
Author(s):  
Nur Nadiah Syuhada Ramli ◽  
Areej A. Alkhaldy ◽  
Abbe Maleyki Mhd Jalil
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Randomised Controlled Trials ◽  
Meta Analysis ◽  
Fasting Blood Glucose ◽  
Coffee Consumption ◽  
Controlled Trials ◽  
Decaffeinated Coffee ◽  
Randomised Controlled

Coffee is rich in phenolic acids, such as caffeic acid and chlorogenic acid (CGA). Polyphenol-rich diets were shown to reduce the risk of metabolic syndrome (MeTS). Background and Objectives: This systematic review and meta-analysis discusses the effects of coffee consumption and its dose-response on MeTS parameters. Materials and Methods: PubMed and Scopus® were searched for relevant articles published between 2015 and 2020. This review focused on randomised controlled trials (RCTs) investigating the effect of coffee consumption on anthropometric measurements, glycaemic indices, lipid profiles, and blood pressure. Data from relevant studies were extracted and analysed using random, fixed, or pooled effects models with 95% confidence intervals (CIs). Results: Green coffee extract (GCE) supplementation (180 to 376 mg) was found to reduce waist circumference (weighted mean difference (WMD) = −0.39; 95% CI: −0.68, −0.10), triglyceride levels (WMD = −0.27; 95% CI: −0.43, −0.10), high−density lipoprotein−cholesterol levels (WMD = 0.62; 95% CI: 0.34, 0.90), systolic blood pressure (WMD = −0.44; 95% CI: −0.57, −0.32), and diastolic blood pressure (WMD = −0.83; 95% CI: −1.40, −0.26). Decaffeinated coffee (510.6 mg) reduced fasting blood glucose levels (WMD = −0.81; 95% CI: −1.65, 0.03). The meta-analysis showed that the intake of GCE containing 180 to 376 mg of CGA (administered in a capsule) and liquid decaffeinated coffee containing 510.6 mg of CGA improved the MeTS outcomes in study participants. Conclusions: The findings of the review suggested that the effect of coffee on MeTS parameters varies depending on the types and doses of coffee administered. A more detailed RCT on specific coffee doses (with adjustment for energy and polyphenol intake) and physical activity is needed to further confirm the observed outcomes.

scholarly journals The Effects of Substance Abuse on Blood Glucose Parameters in Patients with Diabetes: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 15 (12) ◽  
pp. 2691 ◽  
Author(s):  
Omorogieva Ojo ◽  
Xiao-Hua Wang ◽  
Osarhumwese Ojo ◽  
Jude Ibe
Keyword(s):  
Systematic Review ◽  
Substance Abuse ◽  
Blood Glucose ◽  
Meta Analysis ◽  
Fasting Blood Glucose ◽  
Glycated Haemoglobin ◽  
Sensitivity Test ◽  
Postprandial Blood Glucose ◽  
Significant Difference ◽  
Patients With Diabetes

Background: People who abuse substances are at increased risk of metabolic syndrome and diabetes resulting partly from increased cell damage and due to the effects of opioids on glucose homeostasis. Therefore, people with diabetes who abuse substances may carry greater health risks than the general population resulting from their effect on glucose metabolism. These substances may be in the form of cannabis, hallucinogens, opioids, and stimulants. Therefore, the aim of this review was to evaluate the effects of substance abuse on blood glucose parameters in patients with diabetes. Method: Databases including Embase, Psycho-Info, Google Scholar and PubMed were searched systematically for relevant articles from database inception to May 2018. Search terms including medical subject headings (MeSH) based on the Population, Intervention, Comparator and Outcomes (PICO) framework was used to access the databases. Eligible articles were selected based on set inclusion and exclusion criteria. The articles reviewed were evaluated for quality and meta-analysis and sensitivity analysis were carried out using the Review Manager (RevMan 5.3, The Cochrane Collaboration, Copenhagen, Denmark). The Random effects model was used for the data analysis. Results: Twelve studies which met the inclusion criteria were included in the systematic review, while nine articles were selected for the meta-analysis. The results of the meta-analysis showed that substance abuse does not have significant effects (p > 0.05) on postprandial blood glucose and glycated haemoglobin in patients with diabetes. With respect to the effect of substance abuse on fasting blood glucose, while this was significant (p < 0.05) following meta-analysis, the results of the sensitivity test did not demonstrate any significant difference (p > 0.05) between patients who abused substances compared with control. This would suggest that the effect of substance abuse on fasting blood glucose in these patients was not very reliable or not consistent. Conclusions: The effect of substance abuse on glycated haemoglobin and postprandial blood glucose in patients with diabetes was not significant. In the meta-analysis, while the value was slightly lower with respect to postprandial blood glucose, this was slightly higher in relation to HbA1c in the substance abuse group compared with control. On the other hand, the effect of substance abuse on fasting blood glucose was significant (p = 0.03) compared with control, but this was attenuated following a sensitivity test. A range of factors including eating habits, characteristics of drugs, erratic lifestyle of patients may explain the outcome of this review. There is the need for randomised controlled trials that will include diet and medication history in order to fully understand the effect of substance abuse on blood glucose parameters in patients with diabetes.

scholarly journals Effects of Caffeinated and Decaffeinated Coffee Consumption on Metabolic Syndrome Parameters: A Systematic Review and Meta-Analysis of Data from Randomised Controlled Trials

2021 ◽  
Author(s):  
Nur Nadiah Syuhada Ramli ◽  
Areej A Alkhaldy ◽  
Abbe Maleyki Mhd Jalil
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Randomised Controlled Trials ◽  
Meta Analysis ◽  
Fasting Blood Glucose ◽  
Coffee Consumption ◽  
Controlled Trials ◽  
Decaffeinated Coffee ◽  
Randomised Controlled

Coffee is rich in phenolic acids, such as caffeic acid and chlorogenic acid (CGA). Polyphenol-rich diets have been shown to reduce the risk of metabolic syndrome (MeTS). Background and Objectives: This systematic review and meta-analysis discusses the effects of coffee consumption and its dose-response on MeTS parameters. Materials and Methods: PubMed and Scopus® were searched for relevant articles published between 2015 and 2020. This review focused on randomised controlled trials (RCTs) investigating the effect of coffee consumption on anthropometric measurements, glycaemic indices, lipid profiles, and blood pressure. Data from relevant studies were extracted and analysed using random, fixed, or pooled effects models with 95% confidence intervals (CIs). Results: Green coffee extract (GCE) supplementation (180 to 376 mg) was found to reduce waist circumference (weighted mean difference (WMD) = -0.39; 95% CI: -0.68, -0.10), triglyceride levels (WMD = -0.27; 95% CI: -0.43, -0.10), high-density lipoprotein-cholesterol levels (WMD = 0.62; 95% CI: 0.34, 0.90), systolic blood pressure (WMD = -0.44; 95% CI: -0.57, -0.32), and diastolic blood pressure (WMD = -0.83; 95% CI: -1.40, -0.26). Decaffeinated coffee (510.6 mg) reduced the fasting blood glucose levels (WMD = -0.81; 95% CI: -1.65, 0.03). The meta-analysis showed that the intake of GCE containing 180 to 376 mg of CGA (administered in a capsule) and liquid decaffeinated coffee containing 510.6 mg of CGA improved the MeTS outcomes in study participants. Conclusions: The findings of the review suggested that the effect of coffee on MeTS parameters varies depending on the types and doses of coffee administered. A more detailed RCT on specific coffee doses (with adjustment for energy and polyphenol intake) and physical activity is needed to further confirm the observed outcomes.

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