scholarly journals Energetic Glaucoma Segmentation and Classification Strategies using Depth Optimized Machine Learning Strategies

Author(s):  
ELIZABETH JESI V ◽  
SHABNAM MOHAMED ASLAM ◽  
RAMKUMAR G ◽  
SUJATHA M ◽  
ANUSHYA A ◽  
...  

Abstract Glaucoma is a major threatening cause, in which it affects the optical nerve to lead a permanent blindness to individuals. The major causes of Glaucoma are high pressure to eyes, family history, irregular sleeping habits and so on. These kinds of causes leads to Glaucoma easily as well as the affection to such disease leads a heavy damage to the internal optic nervous system and the affected person will get permanent blindness within few months. The eye fluid called aqueous humor is getting blocked inside due to Glaucoma, in normal cases sometimes the fluid comes out from the eye via mesh perspective channel, but this Glaucoma blocks that channel and causes the fluid to getting locked inside and provides the permanent blockage inside. So, that the eyes are getting severe affections such as infection, random blindness in initial stages and so on. The World Health Organization analyzes and reports nearly 80 million people around the globe are affected due to some form of Glaucoma. The major problem with this disease is it is incurable, however, the affection stages can be reduced and maintain the same level of affection as it is for the long period but it is possible only earlier stages of identification. This Glaucoma causes structural affection to the eye ball and it is complex to estimate the cause during regular diagnosis. In medical terms, the Cup to Disc Ratio (CDR) is minimized to the Glaucoma patients suddenly and leads a harmful damage to one's eye in severe manner. The general way to identify the Glaucoma is to take Optical Coherence Tomography (OCT) test, in which it captures the uncovered portion of eye ball (backside) and it is an efficient way to visualize diverse portions of eyes with optical nerve visibility is shown clearly. The OCT images are mainly used to identify the diseases like Glaucoma with proper and robust accuracy levels. In this paper, a new methodology is introduced to identify the Glaucoma on earlier stages called Depth Optimized Machine Learning Strategy (DOMLS), in which it adapts the new optimization logic called Modified K-Means Optimization Logic (MkMOL) to provide best accuracy in results and the proposed approach assures the accuracy level of more than 96.2% with least error rate of 0.002%. This paper focuses on the identification of early stage of Glaucoma and provides an efficient solution to people in case of affection by such disease using OCT images. The exact position point out is handled by using Region of Interest (ROI) based optical region selection, in which it is easy to point the Optical Cup (OC) and Optical Disc (OD). The proposed algorithm of DOMLS proves the accuracy levels in estimation of Glaucoma and shows the practical proofs on resulting section in clear manner.

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
V. Elizabeth Jesi ◽  
Shabnam Mohamed Aslam ◽  
G. Ramkumar ◽  
A. Sabarivani ◽  
A. K. Gnanasekar ◽  
...  

Glaucoma is a major threatening cause, in which it affects the optical nerve to lead to a permanent blindness to individuals. The major causes of Glaucoma are high pressure to eyes, family history, irregular sleeping habits, and so on. These kinds of causes lead to Glaucoma easily, and the effect of such disease leads to heavy damage to the internal optic nervous system and the affected person will get permanent blindness within few months. The major problem with this disease is that it is incurable; however, the affection stages can be reduced and the same level of effect as that for the long period can be maintained but this is possible only in the earlier stages of identification. This Glaucoma causes structural effect to the eye ball and it is complex to estimate the cause during regular diagnosis. In medical terms, the Cup to Disc Ratio (CDR) is minimized to the Glaucoma patients suddenly and leads to harmful damage to one’s eye in severe manner. The general way to identify the Glaucoma is to take Optical Coherence Tomography (OCT) test, in which it captures the uncovered portion of eye ball (backside) and it is an efficient way to visualize diverse portions of eyes with optical nerve visibility shown clearly. The OCT images are mainly used to identify the diseases like Glaucoma with proper and robust accuracy levels. In this work, a new methodology is introduced to identify the Glaucoma in earlier stages, called Depth Optimized Machine Learning Strategy (DOMLS), in which it adapts the new optimization logic called Modified K-Means Optimization Logic (MkMOL) to provide best accuracy in results, and the proposed approach assures the accuracy level of more than 96.2% with least error rate of 0.002%. This paper focuses on the identification of early stage of Glaucoma and provides an efficient solution to people in case of effect by such disease using OCT images. The exact position pointed out is handled by using Region of Interest- (ROI-) based optical region selection, in which it is easy to point the optical cup (OC) and optical disc (OD). The proposed algorithm of DOMLS proves the accuracy levels in estimation of Glaucoma and the practical proofs are shown in the Result and Discussions section in a clear manner.


2020 ◽  
Vol 16 ◽  
Author(s):  
Nitigya Sambyal ◽  
Poonam Saini ◽  
Rupali Syal

Background and Introduction: Diabetes mellitus is a metabolic disorder that has emerged as a serious public health issue worldwide. According to the World Health Organization (WHO), without interventions, the number of diabetic incidences is expected to be at least 629 million by 2045. Uncontrolled diabetes gradually leads to progressive damage to eyes, heart, kidneys, blood vessels and nerves. Method: The paper presents a critical review of existing statistical and Artificial Intelligence (AI) based machine learning techniques with respect to DM complications namely retinopathy, neuropathy and nephropathy. The statistical and machine learning analytic techniques are used to structure the subsequent content review. Result: It has been inferred that statistical analysis can help only in inferential and descriptive analysis whereas, AI based machine learning models can even provide actionable prediction models for faster and accurate diagnose of complications associated with DM. Conclusion: The integration of AI based analytics techniques like machine learning and deep learning in clinical medicine will result in improved disease management through faster disease detection and cost reduction for disease treatment.


2021 ◽  
pp. 197140092198932
Author(s):  
Timo Alexander Auer ◽  
Maike Kern ◽  
Uli Fehrenbach ◽  
Yasemin Tanyldizi ◽  
Martin Misch ◽  
...  

Purpose To characterise peritumoral zones in glioblastoma and anaplastic astrocytoma evaluating T2 values using T2 mapping sequences. Materials and methods In this study, 41 patients with histopathologically confirmed World Health Organization high grade gliomas and preoperative magnetic resonance imaging examinations were retrospectively identified and enrolled. High grade gliomas were differentiated: (a) by grade, glioblastoma versus anaplastic astrocytoma; and (b) by isocitrate dehydrogenase mutational state, mutated versus wildtype. T2 map relaxation times were assessed from the tumour centre to peritumoral zones by means of a region of interest and calculated pixelwise by using a fit model. Results Significant differences between T2 values evaluated from the tumour centre to the peritumoral zone were found between glioblastoma and anaplastic astrocytoma, showing a higher decrease in signal intensity (T2 value) from tumour centre to periphery for glioblastoma ( P = 0.0049 – fit-model: glioblastoma –25.02± 19.89 (–54–10); anaplastic astrocytoma –5.57±22.94 (–51–47)). Similar results were found when the cohort was subdivided by their isocitrate dehydrogenase profile, showing an increased drawdown from tumour centre to periphery for wildtype in comparison to mutated isocitrate dehydrogenase ( P = 0.0430 – fit model: isocitrate dehydrogenase wildtype –10.35±16.20 (–51) – 0; isocitrate dehydrogenase mutated 12.14±21.24 (–15–47)). A strong statistical proof for both subgroup analyses ( P = 0.9987 – glioblastoma R2 0.93±0.08; anaplastic astrocytoma R2 0.94±0.15) was found. Conclusion Peritumoral T2 mapping relaxation time tissue behaviour of glioblastoma differs from anaplastic astrocytoma. Significant differences in T2 values, using T2 mapping relaxation time, were found between glioblastoma and anaplastic astrocytoma, capturing the tumour centre to the peritumoral zone. A similar curve progression from tumour centre to peritumoral zone was found for isocitrate dehydrogenase wildtype high grade gliomas in comparison to isocitrate dehydrogenase mutated high grade gliomas. This finding is in accordance with the biologically more aggressive behaviour of isocitrate dehydrogenase wildtype in comparison to isocitrate dehydrogenase mutated high grade gliomas. These results emphasize the potential of mapping techniques to reflect the tissue composition of high grade gliomas.


2021 ◽  
Author(s):  
Mohamed Mahmoud ◽  
Anna TOKAR ◽  
Melissa ARRIAS ◽  
Christos MYLONAS ◽  
Heini UTUNEN ◽  
...  

UNSTRUCTURED As part of its transformation process to meet the health challenges of the 21st century by creating a motivated and fit-for-purpose global workforce, the World Health Organization (WHO) is developing the first-ever global Learning Strategy for health personnel around the world. Focus group discussions (FGDs) were organized as part of in-depth qualitative research on staff views, visions, and suggestions. Due to the pandemic, a flexible, multi-linguistic, participatory, iterative methodology for digitization of face-to-face FDGs to engage a globally dispersed workforce was implemented.


Proceedings ◽  
2020 ◽  
Vol 54 (1) ◽  
pp. 31
Author(s):  
Joaquim de Moura ◽  
Lucía Ramos ◽  
Plácido L. Vidal ◽  
Jorge Novo ◽  
Marcos Ortega

The new coronavirus (COVID-19) is a disease that is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On 11 March 2020, the coronavirus outbreak has been labelled a global pandemic by the World Health Organization. In this context, chest X-ray imaging has become a remarkably powerful tool for the identification of patients with COVID-19 infections at an early stage when clinical symptoms may be unspecific or sparse. In this work, we propose a complete analysis of separability of COVID-19 and pneumonia in chest X-ray images by means of Convolutional Neural Networks. Satisfactory results were obtained that demonstrated the suitability of the proposed system, improving the efficiency of the medical screening process in the healthcare systems.


In agriculture the major problem is leaf disease identifying these disease in early stage increases the yield. To reduce the loss identifying the various disease is very important. In this work , an efficient technique for identifying unhealthy tomato leaves using a machine learning algorithm is proposed. Support Vector Machines (SVM) is the methodology of machine learning , and have been successfully applied to a number of applications to identify region of interest, classify the region. The proposed algorithm has three main staggers, namely preprocessing, feature extraction and classification. In preprocessing, the images are converted to RGB and the average filter is used to eliminate the noise in the input image. After the pre-processing stage, features such as texture, color and shape are extracted from each image. Then, the extracted features are presented to the classifier to classify an input tomato leaf as a healthy or unhealthy image. For classification, in this paper, a multi-kernel support vector machine (MKSVM) is used. The performance of the proposed method is analysed on the basis of different metrics, such as accuracy, sensitivity and specificity. The images used in the test are collected from the plant village. The proposed method implemented in MATLAB.


Author(s):  
Lokesh Kola

Abstract: Diabetes is the deadliest chronic diseases in the world. According to World Health Organization (WHO) around 422 million people are currently suffering from diabetes, particularly in low and middle-income countries. Also, the number of deaths due to diabetes is close to 1.6 million. Recent research has proven that the occurrence of diabetes is likely to be seen in people aged between 18 and this has risen from 4.7 to 8.5% from 1980 to 2014. Early diagnosis is necessary so that the disease does not go into advanced stages which is quite difficult to cure. Significant research has been performed in diabetes predictions. As time passes, challenges keep increasing to build a system to detect diabetes systematically. The hype for Machine Learning is increasing day to day to analyse medical data to diagnose a disease. Previous research has focused on just identifying the diabetes without specifying its type. In this paper, we have we have predicted gestational diabetes (Type-3) by comparing various supervised and semi-supervised machine learning algorithms on two datasets i.e., binned and non-binned datasets and compared the performance based on evaluation metrics. Keywords: Gestational diabetes, Machine Learning, Supervised Learning, Semi-Supervised Learning, Diabetes Prediction


Author(s):  
Nishanth P

Falls have become one of the reasons for death. It is common among the elderly. According to World Health Organization (WHO), 3 out of 10 living alone elderly people of age 65 and more tend to fall. This rate may get higher in the upcoming years. In recent years, the safety of elderly residents alone has received increased attention in a number of countries. The fall detection system based on the wearable sensors has made its debut in response to the early indicator of detecting the fall and the usage of the IoT technology, but it has some drawbacks, including high infiltration, low accuracy, poor reliability. This work describes a fall detection that does not reliant on wearable sensors and is related on machine learning and image analysing in Python. The camera's high-frequency pictures are sent to the network, which uses the Convolutional Neural Network technique to identify the main points of the human. The Support Vector Machine technique uses the data output from the feature extraction to classify the fall. Relatives will be notified via mobile message. Rather than modelling individual activities, we use both motion and context information to recognize activities in a scene. This is based on the notion that actions that are spatially and temporally connected rarely occur alone and might serve as background for one another. We propose a hierarchical representation of action segments and activities using a two-layer random field model. The model allows for the simultaneous integration of motion and a variety of context features at multiple levels, as well as the automatic learning of statistics that represent the patterns of the features.


2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Harshima Disvini Wijesinghe ◽  
Ajith Malalasekera

Giant cell urothelial carcinoma is a rare variant of bladder cancer recognized by the current World Health Organization classification of urologic tumours. It is an aggressive tumour with a poor prognosis that usually presents at an advanced stage. It is characterized histologically by pleomorphic giant cells. We discuss a case of giant cell urothelial carcinoma presenting at an early stage in a previously well 62-year-old woman. Histology showed a tumour comprising pancytokeratin positive bizarre mononuclear and multi-nuclear giant cells admixed with areas of conventional urothelial carcinoma and carcinoma in situ. Three-month follow-up cystoscopy and magnetic resonance imaging showed no evidence of recurrence or pelvic lymphadenopathy.


2022 ◽  
pp. 383-393
Author(s):  
Lokesh M. Giripunje ◽  
Tejas Prashant Sonar ◽  
Rohit Shivaji Mali ◽  
Jayant C. Modhave ◽  
Mahesh B. Gaikwad

Risk because of heart disease is increasing throughout the world. According to the World Health Organization report, the number of deaths because of heart disease is drastically increasing as compared to other diseases. Multiple factors are responsible for causing heart-related issues. Many approaches were suggested for prediction of heart disease, but none of them were satisfactory in clinical terms. Heart disease therapies and operations available are so costly, and following treatment, heart disease is also costly. This chapter provides a comprehensive survey of existing machine learning algorithms and presents comparison in terms of accuracy, and the authors have found that the random forest classifier is the most accurate model; hence, they are using random forest for further processes. Deployment of machine learning model using web application was done with the help of flask, HTML, GitHub, and Heroku servers. Webpages take input attributes from the users and gives the output regarding the patient heart condition with accuracy of having coronary heart disease in the next 10 years.


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