scholarly journals Relationship of Objectively Measuring Physical Activity and Sitting Time on Plasma Lipid Metabolism During Pregnancy

2021 ◽  
Author(s):  
Hanqing Chen ◽  
Casper J. P. Zhang ◽  
Xuanbi Fang ◽  
Zijian Tan ◽  
Ni Yan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Total Cholesterol ◽  
Early Pregnancy ◽  
Plasma Lipids ◽  
Plasma Lipid ◽  
First Trimester ◽  
Sitting Time ◽  
Second Trimester ◽  
Lipid Status ◽  
Linear Association

Abstract Background: Physical activity (PA) was commonly associated with pregnancy outcomes, including plasma lipids. We hypothesized that women with more PA would improve plasma lipid status than those with less PA during pregnancy. This study aimed to investigate the association of PA and sitting time with blood lipids in the first two trimesters. Methods: A prospective study was performed among 197 cases aged 18 to 40 recruited from a regional university affiliated hospital in south China. accelerometer were used to measure maternal PA in two trimesters (first measurement within 10th to 14th week of gestation and second measurement within 20th to 24th weeks of gestation; 7 consecutive days for each measurement). Maternal fasting venous blood was collected to test plasma lipids (cholesterol, triglyceride, low- and high-density lipoprotein [LDL and HDL]) in each of two trimesters.Results: A total of 197 cases completed this study. After adjusting for age and pre-pregnancy BMI, moderate PA of the first trimester was inversely linear associated with triglycerides in early pregnancy (β=-0.231, P=0.002). And it was also inversely significant linear association with triglycerides of the second trimester (β=-0.196, P=0.006). Moderate PA in early pregnancy showed a positively non-significant linear association with HDL levels of the first trimester (β=0.134, P=0.068). However, sitting time of the second trimester were positively non-significant associated with total cholesterol (β=0.126, P=0.080）and LDL levels (β=0.124, P=0.082）of the second trimester.Conclusions: Sitting time of the second trimester would positively associated with total cholesterol and LDL levels of the mid pregnancy. Higher moderate PA of early pregnancy was associated with lower triglycerides, and this effect lasting to the mid pregnancy. Therefore, pregnant women should be encourage to increase moderate PA and decrease sitting time from early pregnancy to improve lipid status.

scholarly journals Hypothyroidism incidence in and around pregnancy: a Danish nationwide study

2016 ◽  
Vol 175 (5) ◽  
pp. 387-393 ◽  
Author(s):  
S L Andersen ◽  
A Carlé ◽  
J Olsen ◽  
P Laurberg
Keyword(s):  
Incidence Rate ◽  
Early Pregnancy ◽  
Incidence Rate Ratio ◽  
First Trimester ◽  
Population Based ◽  
Second Trimester ◽  
Third Trimester ◽  
First Child ◽  
Born Child ◽  
Pregnancy And Postpartum

Objective Immunological changes in and after a pregnancy may influence the onset of autoimmune diseases. An increased incidence of hyperthyroidism has been observed both in early pregnancy and postpartum, but it remains to be studied if the incidence of hypothyroidism varies in a similar way. Design Population-based cohort study using Danish nationwide registers. Method All women who gave birth to a singleton live-born child in Denmark from 1999 to 2008 (n = 403 958) were identified, and data on hospital diagnosis of hypothyroidism and redeemed prescriptions of thyroid hormone were extracted. The overall incidence rate (IR) of hypothyroidism during 1997–2010 and the IR in three-month intervals before, during and after the woman’s first pregnancy in the study period were calculated and compared with the IR of hyperthyroidism. Results Altogether 5220 women were identified with onset of hypothyroidism from 1997 to 2010 (overall IR 92.3/100 000/year) and 1572 women developed hypothyroidism in the period from 2 years before to 2 years after birth of the first child in the study period. The incidence of hypothyroidism decreased during the pregnancy (incidence rate ratio (IRR) vs overall IR in the rest of the study period: first trimester: 0.89 (95% CI: 0.66–1.19), second trimester: 0.71 (0.52–0.97), third trimester: 0.29 (0.19–0.45)) and increased after birth with the highest level at 4–6 months postpartum (IRR 3.62 (2.85–4.60)). Conclusion These are the first population-based data on the incidence of hypothyroidism in and around pregnancy. The incidence declined during pregnancy followed by a sharp increase postpartum. Notably, hypothyroidism as opposed to hyperthyroidism showed no early pregnancy increase.

Additional Physical Education and Plasma Lipids and Apoproteins: A 3-Year Intervention Study

1994 ◽  
Vol 6 (2) ◽  
pp. 128-139 ◽  
Author(s):  
Maria L. Zonderland ◽  
Wietze B.M. Erich ◽  
Wouter Kortlandt ◽  
D. Willem Erkelens
Keyword(s):  
Physical Activity ◽  
Body Composition ◽  
Physical Education ◽  
Intervention Study ◽  
Plasma Lipids ◽  
Pubertal Development ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Physical Activities ◽  
Intervention Effect

A 3-year controlled intervention was used to study the influence of physical activity on the plasma lipid and apoprotein profile of 10-year-old Dutch schoolchildren. Twice-a-year measurements were taken of height, weight, body composition (skinfolds), pubertal development (Tanner stages), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), triglycerides (TG), apoproteins A-I and B (immunoturbidimetry), and participation in physical activities. The effect of the intervention was analyzed with a MANOVA. The intervention did not affect the level of the lipids and apoproteins of the boys. In the girls, the intervention led to a smaller increase of TG and a larger decrease of apoprotein A-I. There may be two explanations for the limited intervention effect. First, it may be due to the healthy baseline plasma lipid and apoprotein profile, which leaves little room for improvement. Second, the exercise intensity during the physical education classes may have been too low to bring about the desired effect.

A Longitudinal Genetic Study of Plasma Lipids in Adolescent Twins

2007 ◽  
Vol 10 (1) ◽  
pp. 127-135 ◽  
Author(s):  
Rita P. S. Middelberg ◽  
Nicholas G. Martin ◽  
John B. Whitfield
Keyword(s):  
Total Cholesterol ◽  
Environmental Effects ◽  
Plasma Lipids ◽  
Low Density Lipoprotein ◽  
Environmental Influences ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Lipids And Lipoproteins ◽  
Adolescent Twins ◽  
Over Time

AbstractPlasma lipids such as high-density lipoprotein (HDL), low-density lipoprotein (LDL), total cholesterol and triglyceride levels contribute to variation in the risk of cardiovascular disease. The early stages of atherosclerosis in childhood have also been associated with changes in triglycerides, LDL and HDL. Heritability estimates for lipids and lipoproteins for adolescents are in the range .71 to .82, but little is known about changes of genetic and environmental influences over time in adolescence. We have investigated the contribution of genetic and environmental influences to variation in lipids in adolescent twins and their nontwin siblings using longitudinal twin and family data. Plasma HDL and LDL cholesterol, total cholesterol and triglycerides data from 965 twin pairs at 12, 14 and 16 years of age and their siblings have been analyzed. Longitudinal genetic models that included effects of age, sex and their interaction were fitted to assess whether the same or different genes influence each trait at different ages. Results suggested that more than one genetic factor influences HDL, LDL, total cholesterol and triglycerides over time at ages 12, 14 and 16 years. There was no evidence of shared environmental effects except for HDL and little evidence of long-term nonshared environmental effects was found. Our study suggested that there are developmental changes in the genes affecting plasma lipid concentrations across adolescence.

Daily Physical Activity and Plasma Lipid Concentrations in Early Pregnancy

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S432
Author(s):  
SeonAe Yeo ◽  
Nick Rafael ◽  
Kathy Bishop ◽  
Robert Kiningham
Keyword(s):  
Physical Activity ◽  
Early Pregnancy ◽  
Plasma Lipid ◽  
Daily Physical Activity

scholarly journals Maternal nutrition in early pregnancy

1977 ◽  
Vol 38 (3) ◽  
pp. 497-506 ◽  
Author(s):  
R. W. Smithells ◽  
Carol Ankers ◽  
Margaret E. Carver ◽  
Dorothy Lennon ◽  
C. J. Schorah ◽  
...  
Keyword(s):  
Social Security ◽  
Early Pregnancy ◽  
Maternal Age ◽  
Maternal Nutrition ◽  
First Trimester ◽  
Social Classes ◽  
Second Trimester ◽  
Department Of Health ◽  
Dietary Records ◽  
First Trimester Of Pregnancy

1. Mean daily nutrient intakes of 195 women in the first trimester of pregnancy were assessed by weighed dietary records.2. In comparison with recommended intakes for non-pregnant women aged 18-55 years (Department of Health and Social Security, (1969), more than two-thirds of the subjects were having insufficient energy, iron and cholecalciferol. Unsatisfactory intakes of other nutrients were not uncommon. In relation to recom mended intakes for the second trimester Department of Health and Social Security, (1969), all mothers were having insufficient cholecalciferol and more than 80 % of mothers had unsatisfactory intakes of energy and Fe.3. Intakes appreciably lower than those recommended were associated with the following factors: social classes III, IV and V; maternal age under 20 years; smoking ten or more cigarettes daily; vomiting on more than 3 d/week.

scholarly journals Dietary intake of energy and selected nutrients and plasma lipid profile in young women and men with different levels of physical activity

2013 ◽  
Vol 5 (1) ◽  
pp. 99-107
Author(s):  
Marzena Malara ◽  
Elżbieta Hübner-Woźniak
Keyword(s):  
Physical Activity ◽  
Dietary Intake ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Young Women ◽  
Venous Blood ◽  
Plasma Lipid ◽  
Blood Collection ◽  
Plasma Lipid Profile ◽  
Different Levels

Summary Study aim: The purpose was to assess dietary intake of energy and selected nutrients and plasma lipid profile in young women and men with different levels of physical activity. Material and methods: The research included a total of 116 female and male students at the University of Physical Education who differed in their levels of physical activity. Analysis of the diets was based on 24-hour dietary interviews collected over 4 days prior to blood collection. Concentrations of total cholesterol (TC), HDL cholesterol (HDL-C), and triacylglycerol (TG) were measured in venous blood. In addition, the concentration of LDL cholesterol (LDL-C) and the ratios of TC / HDL-C and LDL-C/HDL-C were calculated. Results: Women, regardless of their physical activity levels, were characterized by a significantly higher concentration of total cholesterol in plasma (4.8 and 4.5 mmol/L, respectively - in training participants; 4.7 and 4.3 mmol/L, respectively - in non-training participants), although their dietary intake of cholesterol was significantly lower in comparison with the corresponding groups of men (282.0 and 484.7 mg, respectively - in training participants; 252.6 and 400.2 mg, respectively - in non-training participants). A trend toward a worse lipid profile of training women and men compared with the corresponding groups of non-training participants was also observed. Conclusions: Increased physical activity in the groups of training women and men was not a sufficient stimulus to induce positive changes in their lipid profiles. Nor can it be excluded that the observed differences were the result of diet, as dietary intake of cholesterol in the groups of training women and men was higher compared with the corresponding groups of non-training participants.

Chorionic bump: Progression to a subamniotic hematoma

Ultrasound ◽  
2021 ◽  
pp. 1742271X2110085
Author(s):  
Claudia Galleguillos ◽  
Waldo Sepulveda
Keyword(s):  
Early Pregnancy ◽  
Deleterious Effect ◽  
Pregnancy Loss ◽  
Alternative Explanation ◽  
First Trimester ◽  
Early Embryo ◽  
Ultrasound Finding ◽  
Second Trimester ◽  
First Trimester Scan

Introduction A chorionic bump is an increasingly recognized ultrasound finding in first-trimester scans, which has been associated with early pregnancy loss. In ongoing second-trimester pregnancies, however, chorionic bumps usually resolve over time with no deleterious effect on the fetus. In this report, we describe the incidental ultrasound detection of a chorionic bump in early pregnancy and its progression to a subamniotic hematoma in the second trimester of pregnancy that persisted as such until delivery. Case Report A round, echogenic mass protruding from the choriodecidual surface measuring 13 × 11 × 8 mm was first identified during a transvaginal scan at 6.3 weeks’ gestation. Subsequent follow-up scan at 8.3 weeks revealed an increase in the size of the chorionic bump to 25 × 20 × 19 mm, which remained stable as determined by the routine late first-trimester scan. At the second-trimester scan, a subamniotic hematoma was identified in the surface of the placenta, close to the insertion of the umbilical cord. Subsequently, the pregnancy proceeded uneventfully. Discussion The etiopathology and clinical significance of a chorionic bump remain unclear. The case herein reported demonstrates that a chorionic bump can grow considerably without having a deleterious effect on the early embryo and, occasionally, can persist throughout pregnancy as a subamniotic hematoma. Conclusion A chorionic bump can occasionally progress to a subamniotic hematoma from the second trimester onwards. This observation further supports the hypothesis that a chorionic bump is the result of choriodecidual bleeding. An alternative explanation for the development of subamniotic hematomas is proposed.

Cardioprotective Effects of Diet with Different Grains on Lipid Profiles and Antioxidative System in Obesity-Induced Rats

2012 ◽  
Vol 82 (2) ◽  
pp. 85-93 ◽  
Author(s):  
Y. Kim ◽  
H. Shin ◽  
S. Lee
Keyword(s):  
Aortic Wall ◽  
Plasma Lipids ◽  
Antioxidant Activities ◽  
Plasma Lipid ◽  
Density Lipoprotein ◽  
Thiobarbituric Acid ◽  
Lipid Profiles ◽  
Dietary Lipids ◽  
Male Rats

In the present study, the nutritional quality of four grains including adlay (AD), buckwheat (BW), glutinous barley (GB), and white rice (WR) were evaluated in terms of plasma lipid parameters, gut transit time, and thickness of the aortic wall in rats. The rats were then raised for 4 weeks on the high-fat diet based on the American Institute of Nutrition-93 (AIN-93 G) diets containing 1 % cholesterol and 20 % dietary lipids. Forty male rats were divided into 4 groups and raised for 4 weeks with a diet containing one of the following grains: WR, AD, BW, or WB. The level of thiobarbituric acid-reactive substances (TBARS) in liver was shown to be higher in rats by the order of those fed WR, AD, GB, and BW. This indicates that other grains decreased oxidative stress in vivo more than WR. The superoxide dismutase, glutathione, glutathione peroxidase, and glutathione reductase levels in the AD, BW, and GB groups were significantly higher than those in the WR group (p < 0.05). Plasma lipid profiles differed significantly according to grain combination, and decreased aortic wall thickness was consistent with the finding of decreased plasma low-density lipoprotein cholesterol (LDL-C) (p < 0.05) and increased high-density lipoprotein (HDL-C) in rats fed AD, BW, and GB (p < 0.001). The antioxidant and hypolipidemic capacities of grains are quite high, especially those of adlay, buckwheat, and glutinous barley. In conclusion, this study has demonstrated that the whole grains had a cardioprotective effect. This effect was related to several mechanisms that corresponded to lowering plasma lipids, decreasing TBARS, and increasing antioxidant activities.

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