scholarly journals The Prevalence of Adenomas, AAs, and CRCs in Colonoscopy Screening Among Average-Risk Individuals in China

2021 ◽  
Author(s):  
Yan Gong ◽  
Yansong Zheng ◽  
Rilige Wu ◽  
Miao Liu ◽  
Hong Li ◽  
...  
Keyword(s):  
Age Groups ◽  
Screening Colonoscopy ◽  
Average Risk ◽  
Number Of Patients ◽  
High Prevalence ◽  
Male Sex ◽  
Advanced Adenomas ◽  
Old Men ◽  
Number Of Individuals ◽  
Serrated Adenomas

Abstract Background: Screening colonoscopy has historically been recommended starting at the age of 50. However, the recommended age for beginning screening has recently been reduced to 45 independent of sex. However, studies on screening colonoscopies of average-risk individuals in China are sparse. This study aimed to determine and compare the prevalence of adenomas, advanced adenomas (AAs), and colorectal cancers (CRCs) and the number of individuals needing screening in an average-risk Chinese population of different ages and sexes.Methods: A total of 53,152 individuals undergoing colonoscopy were included from January 2013 to December 2019. We analysed and compared the prevalence of adenomas, AAs, and CRCs and the number of individuals needing screening in different age groups of men and women.Results: The average age of males was 48.80 years (SD, 8.47 years), that of females was 50.00 years (SD, 9.00 years), and the sex ratio was 66.28% (n=35,226) vs. 33.72% (n=17,926). The prevalence of adenomas, AAs, serrated adenomas and CRCs was 14.51% ([95% CI 14.21–14.81], n=7713), 3.04% ([95% CI 2.90–3.19], n=1617), 1.23% ([95% CI 1.01–1.32], n=653) and 0.59% ([95% CI 0.52–0.65], n=313), respectively. Male sex was significantly associated with a high prevalence of adenomas (17.14% [95% CI 16.74–17.53] vs 9.36% [95% CI 8.94–9.79], P<0.001), AAs (3.67% [95% CI 3.47–3.87] vs 1.81% [95% CI 1.61–2.00], P<0.001) and serrated adenomas (1.56% [95% CI 1.43–1.69] vs. 0.59% [95% CI 0.47–0.70], P<0.001). The prevalence of AAs in 45- to 49-year-old individuals was 3.17% (95% CI 2.80–3.55) in men and 1.49% (95% CI 1.12–1.86) in women. The number of men needing screening(NNS) was 31.55 (95% CI 28.17–35.71), while the number of women was 67.11 (95% CI 53.76–89.29). The prevalence and number of patients needing screening for AAs in men aged 45–49 years were close to those in women aged 65–69 years (31.55 [95% CI, 28.17–35.71] vs. 29.07 [95% CI, 21.05–46.73]).Conclusions: The prevalence of adenomas, AAs, and serrated adenomas increased with age. Males had a higher prevalence rate than females. The prevalence and NNS of AAs in 45- to 49-year-old men were close to those in 65- to 69-year-old women.

Findings on Colonoscopy after Diverticulitis: A Multicenter Review

2019 ◽  
Vol 85 (12) ◽  
pp. 1381-1385 ◽  
Author(s):  
Adam Studniarek ◽  
Kunal Kochar ◽  
Christina Warner ◽  
Saleh Eftaiha ◽  
Sandra Naffouj ◽  
...  
Keyword(s):  
Diverticular Disease ◽  
Acute Diverticulitis ◽  
Teaching Hospitals ◽  
Average Risk ◽  
Major Teaching ◽  
History Of ◽  
Advanced Adenomas ◽  
Current Guidelines ◽  
Villous Adenomas ◽  
Serrated Adenomas

Diverticular disease is a common problem where patients with diverticulosis have a 1–4 per cent risk of acute diverticulitis. Current guidelines recommend a colonoscopy after.the resolution of acute diverticulitis. The aim of this study was to evaluate the yield of significant findings on colonoscopy after an episode of diverticulitis. This is a retrospective analysis of patients who underwent colonoscopy after an episode of diverticulitis between November 2005 and August 2017 at three major teaching hospitals. Advanced adenomas were defined as adenomas ≥1 cm, serrated adenomas, and tubulovillous or villous adenomas. A total of 584 patients (298 males; 51%) underwent colonoscopy for a history of diverticulitis after resolution of acute symptoms. Colonoscopy was complete in 488 patients (84%). Among these 488 patients, 446 had diverticular disease, 31 had advanced adenomas, and four had adenocarcinomas. Colonoscopies were incomplete in 96 patients (16%). Forty-six of those patients underwent surgery. The overall incidence of advanced adenomas and adenocarcinomas was 32 (5.4%) and nine (1.5%), respectively. In our study, the prevalence of advanced adenomas and adenocarcinomas was relatively high compared with the average risk individuals. Our findings support that patients after an episode of diverticulitis should continue to get a colonoscopy.

scholarly journals High Definition Colonoscopy Combined with i-SCAN Imaging Technology Is Superior in the Detection of Adenomas and Advanced Lesions Compared to High Definition Colonoscopy Alone

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Erik A. Bowman ◽  
Patrick R. Pfau ◽  
Arnab Mitra ◽  
Mark Reichelderfer ◽  
Deepak V. Gopal ◽  
...  
Keyword(s):  
White Light ◽  
Outcome Measurement ◽  
Screening Colonoscopy ◽  
Average Risk ◽  
High Definition ◽  
Polyp Size ◽  
Endoscopic Screening ◽  
White Light Endoscopy ◽  
Adenoma Detection ◽  
Advanced Adenomas

Background. Improved detection of adenomatous polyps using i-SCAN has mixed results in small studies. Utility of i-SCAN as a primary surveillance modality for colorectal cancer screening during colonoscopy is uncertain. Aim. Comparing high definition white light endoscopy (HDWLE) to i-SCAN in their ability to detect adenomas during colonoscopy. Methods. Prospective cohort study of 1936 average risk patients who had a screening colonoscopy at an ambulatory procedure center. Patients underwent colonoscopy with high definition white light endoscopy withdrawal versus i-SCAN withdrawal during endoscopic screening exam. Primary outcome measurement was adenoma detection rate for i-SCAN versus high definition white light endoscopy. Secondary measurements included polyp size, pathology, and morphology. Results. 1007 patients underwent colonoscopy with i-SCAN and 929 with HDWLE. 618 adenomas were detected in the i-SCAN group compared to 402 in the HDWLE group p<0.01. More advanced adenomas (≥10 mm) were found by i-SCAN, 79 versus 47 p=0.021 and based upon histology alone 37 versus 18 p=0.028. Conclusions. i-SCAN detected significantly more adenomas and advanced adenomas compared to high definition white light endoscopy.

scholarly journals 1163 Proximal Advanced Adenomas are More Common Among Urban Hispanics Than African Americans Undergoing Average-Risk Screening Colonoscopy

2012 ◽  
Vol 142 (5) ◽  
pp. S-212-S-213
Author(s):  
Kristen K. Lee ◽  
Lina Jandorf ◽  
Linda D. Thelemaque ◽  
Cristina Villagra ◽  
Steven H. Itzkowitz
Keyword(s):  
African Americans ◽  
Screening Colonoscopy ◽  
Average Risk ◽  
Risk Screening ◽  
Advanced Adenomas

scholarly journals Sleep disorder trends in 1988–2018 among the 25–64 years old population in Russia/Siberia (WHO MONICA Psychosocial study)

2021 ◽  
Vol 13 (3) ◽  
pp. 42-47
Author(s):  
V. V. Gafarov ◽  
E. A. Gromova ◽  
D. O. Panov ◽  
I. V. Gagulin ◽  
A. N. Tripelgorn ◽  
...  
Keyword(s):  
Sleep Disorders ◽  
Sleep Disorder ◽  
Representative Sample ◽  
Age Groups ◽  
Fold Increase ◽  
Older Age ◽  
Age Group ◽  
Younger Women ◽  
High Prevalence ◽  
Old Men

Objective: to study sleep disorders prevalence and trends among the population of Novosibirsk (age group 25–64 years) in 1988–2018.Patients and methods. We screened a representative sample of a 25–64-year-old population: in 1988–1989 (II screening: 725 men, mean age – 43.4±0.4 years, response – 71.3%; 710 women, mean age – 44.8±0.4 years, response – 72%); in 1994–1995 (III screening: 647 men, mean age – 44.3±0.4 years, response – 82.1%; 391 women, mean age – 45.4±0.4 years, response – 72.5%); in 2003–2005 (IV screening: 576 men, mean age – 54.23±0.2 years, response – 61%; 1074 women, mean age – 54.27±0.2 years, response – 72%); in 2013–2016 (V screening: 427 men, mean age – 34±0.4 years, response – 71%; 548 women, mean age – 35±0.4 years, response – 72%); in 2016–2018 (VI screening: 275 men, mean age – 49±0.4 years, response – 72%; 390 women, mean age – 45±0.4 years, response – 75%) according to the standard MONICA Psychosocial study (MOPSY) protocol. Sleep disorders in the studied population were assessed with Jenkins Sleep Questionnaire.Results and discussion. We found a high prevalence of sleep disorders among the 25–64 years old population with the following trends: decrease from 1988–1989 to 1994–1995 (men – 11 and 8.6%, women – 21.8 and 16.6% respectively); increase in 2003–2018 (men – 13.1%, women – 20.5%). An increase in sleep disorders prevalence in 2003–2018 occurred mainly due to older age groups – 45–64 years (χ2 =122.061; υ=16; p<0.001 – men; χ2 =230.626; υ=16; p<0.001 – women). In 1988–2018 there was a 2-fold increase in sleep disorders prevalence among women than men in all age groups. This increase in sleep disorders prevalence was associated with increasing age, reaching its maximum in the 55–64 age group (men: 1988–1989 – 20.8%, 1994–1995 – 12.1%, 2016–2018 – 19.7%; χ2 =41.093; υ=12; p<0.001; women: 35.8; 21.8; 24.9% respectively; χ2 =22.01; υ=12; p<0.001). Different trends were observed in 25–44 years old women in 1988–2018 and in 35–44 years old men in 2013–2016: sleep disorders prevalence decreased (25–44 years old women: in 1988–1989 – 13.7%, in 1994–1995 – 7.9%, in 2013–2016 – 5.7%; χ2 =24.715; υ=8; p<0.001; 35–44 years old women 35–44: in 1988–1989 – 17.9%, in 1994–1995 – 20%, in 2013–2016 – 14.2%, in 2016–2018 – 10.3%; χ2 =21.177; υ=12; p<0.001 respectively; men: in 1988–1989 – 9.5%, in 1994–1995 – 9.3%, in 2013–2016 – 4.2% and in 2016–2018 – 11%; χ2 =12.67; υ=12; p<0.05 respectively).Conclusion. We found a high prevalence of sleep disorders among the 25–64 years old population with the following trends: a decrease from 1988–1989 to 1994–1995; an increase in 2003–2018 mainly due to older age groups. Sleep disorders prevalence decreased in younger women in 1988–2018. There also was a 2-fold increase in sleep disorders prevalence in women than men in all age groups and with increasing age in 1988–2018.

COGNITIVE DEFICIENCY AT ISCHEMIC OM STROKE

2020 ◽  
Vol 1 (1) ◽  
pp. 55-57
Author(s):  
Dildora Khaydarova ◽  
◽  
Hilola Davronova ◽  
Asliddin Akbarov ◽  
Keyword(s):  
Social Problems ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Number Of Patients ◽  
High Prevalence ◽  
The World ◽  
Cognitive Deficiency ◽  
Complications And Mortality

Cerebrovascular diseases remain one of the most pressing medical and social problems in many countries of the world, due to their high prevalence, severity of complications and mortality. In Uzbekistan, the number of patients with cerebral stroke is quite large -about 40-45 thousandcases of cerebral stroke are registered annually

Features of the complex treatment of ulcerative colitis in clinical practice

2020 ◽  
pp. 6-11
Author(s):  
Svetlana Svetlana ◽  
Mikhail Klimentov ◽  
Olga Neganova ◽  
Alina Nazmieva ◽  
Anastasiya Kochurova
Keyword(s):  
Ulcerative Colitis ◽  
Clinical Practice ◽  
Statistical Study ◽  
Age Groups ◽  
Length Of Hospital Stay ◽  
Unknown Etiology ◽  
Number Of Patients ◽  
First Republic ◽  
Bowel Diseases ◽  
Inflammatory Bowel

Nowadays there are certain difficulties in the early diagnosis of ulcerative colitis, proceeding with minimal intestinal symptoms. The etiology of the disease remains unclear to this day; there is no exact information about the prevalence of the disease due to the large number of latent forms and the low number of patients seeking medical help. This article presents the results of a retrospective analysis of the incidence of ulcerative colitis in the coloproctology department of the First Republic Clinical Hospital of Izhevsk. The study was conducted to assess the frequency of occurrence and determine the internal picture of ulcerative colitis. To achieve this goal, we selected 34 patients with ulcerative colitis. A statistical study was conducted on the following criteria: gender composition, age groups, forms of the disease, localization, complications, and main complaints. The length of hospital stay often was not more than 20 days. The literature on this pathology was also studied and presented in the form of a theoretical basis, which consisted of the determination and etiology of inflammatory bowel diseases. Due to the unknown etiology, insufficiently studied pathogenesis, difficult differential diagnosis with other intestinal diseases and insufficiently perfect treatment methods, there are a large number of unresolved problems in the field of ulcerative colitis. That is why, in this article we tried to reveal the problem of the features of the course and complex therapy of that disease in clinical practice.

The Prevalence of Vitamin D Deficiency in Iran: A Literature Review

2020 ◽  
Vol 16 (7) ◽  
pp. 1015-1027
Author(s):  
Mohammad Bagherniya ◽  
Zahra Khorasanchi ◽  
Mina S. Bidokhti ◽  
Gordon A. Ferns ◽  
Mitra Rezaei ◽  
...  
Keyword(s):  
Vitamin D ◽  
Literature Review ◽  
Vitamin D Deficiency ◽  
Medical Condition ◽  
Scientific Information ◽  
Age Groups ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Vitamin D Levels ◽  
High Prevalence

Background: Vitamin D deficiency is a common medical condition worldwide. In Iran, it has been reported that between 30-90% of people have vitamin D deficiency. However, its distribution in different parts of the country and among different age and regional groups is unclear. Therefore, the aim of this study was to review the recent literature on vitamin D deficiency in Iran. Methods: The literature review was performed using Web of Science, PubMed-Medline, Scopus and Scientific Information Database (SID) with a cut-off date of November 2016 to identify articles on vitamin D status in Iran published in the last 10 years. Studies in English and Persian that reported vitamin D levels in male and female subjects of all age groups and in healthy populations were included. Results: From 325 studies that were initially retrieved, 82 articles met the inclusion criteria. A high prevalence of vitamin D deficiency was reported, and in some regions, this was reported as >90% and was found in all age groups and in all regions of Iran. Conclusion: This review highlights the very high prevalence of vitamin D deficiency in Iran. It will be important to recognize the importance of vitamin D deficiency as a major public health problem in Iran.

scholarly journals Characteristics of Osteoporosis & Osteoporotic Fractures in Korea Based on Health Insurance Review and Assessment (HIRA) Database: 2009–2017

Healthcare ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 324
Author(s):  
Ho-Seok Oh ◽  
Sung-Kyu Kim ◽  
Hyoung-Yeon Seo
Keyword(s):  
Health Insurance ◽  
Age Groups ◽  
Osteoporotic Fractures ◽  
Prescription Data ◽  
Diagnostic Codes ◽  
Number Of Patients ◽  
Upper And Lower Extremities ◽  
Fractures Of The Spine ◽  
And Gender ◽  
Age Range

To investigate the incidence and characteristics of osteoporosis and osteoporotic fractures in Korea, we used the Health Insurance Review and Assessment Service (HIRA) database. Patients over 50 years old, who were diagnosed or treated for osteoporosis and osteoporotic fractures in all hospitals and clinics, were analyzed between 1 January 2009 and 31 December 2017 by using the HIRA database that contains prescription data and diagnostic codes. These data were retrospectively analyzed by decade and age-specific and gender-specific incidents in each year. We also evaluated other characteristics of patients including medication state of osteoporosis, primary used medical institution, regional-specific incidence of osteoporosis, and incidence of site-specific osteoporotic fractures. The number of osteoporosis patients over 50 years old, as diagnosed by a doctor, steadily increased from 2009 to 2017. The number of osteoporosis patients was notably greatest in the 60′s and 70′s age groups in every study period. Patients undergoing treatment for osteoporosis increased significantly (96%) from 2009 to 2017. Among the patients diagnosed with osteoporosis, the proportion who experienced osteoporotic fracture increased gradually (60%) from 2009 to 2017. The number of patients with osteoporotic fractures of the spine and hip was highest in the 70 to 90 age range, and the number of patients with osteoporotic fractures in the upper and lower extremities was highest in the 50 to 70 age range. Understanding the trends of osteoporosis in Korea will contribute to manage the increased number of patients with osteoporosis and osteoporotic fractures.

scholarly journals Letter to the Editor: Microbiota in the Respiratory System—A Possible Explanation to Age and Sex Variability in Susceptibility to SARS-CoV-2

2021 ◽  
Vol 14 ◽  
pp. 117863612098860
Author(s):  
Vishal Shah
Keyword(s):  
Respiratory System ◽  
Elderly Population ◽  
Age Groups ◽  
The Elderly ◽  
Elderly Adult ◽  
Human Respiratory Tract ◽  
System A ◽  
Number Of Patients ◽  
Children And Young Adults ◽  
Age And Sex

The Human respiratory tract is colonized by a variety of microbes and the microbiota change as we age. In this perspective, literature support is presented for the hypothesis that the respiratory system microbiota could explain the differential age and sex breakdown amongst COVID-19 patients. The number of patients in the older and elderly adult group is higher than the other age groups. The perspective presents the possibility that certain genera of bacteria present in the respiratory system microbiota in children and young adults could be directly or through eliciting an immune response from the host, prevent full-fledged infection of SARS-CoV-2. The possibility also exists that the microbiota in older adults and the elderly population have bacteria that make it easier for the virus to cause infection. I call upon the scientific community to investigate the link between human microbiota and SARS-CoV-2 susceptibility to further understand the viral pathogenesis.

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