COGNITIVE DEFICIENCY AT ISCHEMIC OM STROKE

2020 ◽  
Vol 1 (1) ◽  
pp. 55-57
Author(s):  
Dildora Khaydarova ◽  
◽  
Hilola Davronova ◽  
Asliddin Akbarov ◽  
Keyword(s):  
Social Problems ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Number Of Patients ◽  
High Prevalence ◽  
The World ◽  
Cognitive Deficiency ◽  
Complications And Mortality

Cerebrovascular diseases remain one of the most pressing medical and social problems in many countries of the world, due to their high prevalence, severity of complications and mortality. In Uzbekistan, the number of patients with cerebral stroke is quite large -about 40-45 thousandcases of cerebral stroke are registered annually

scholarly journals Prevalence of Depression Symptoms in Diabetes Mellitus

2018 ◽  
Vol 6 (2) ◽  
pp. 340-343 ◽  
Author(s):  
Salih Eker
Keyword(s):  
Diabetes Mellitus ◽  
Depressive Disorder ◽  
Depression Symptoms ◽  
Strong Indicator ◽  
Number Of Patients ◽  
High Prevalence ◽  
Prevalence Of Depression ◽  
The World

BACKGROUND: Diabetes mellitus (DM) is one of the most prevalent diseases all over the world. Prevalence of DM in Turkey is 13.7%. Depression is another condition which has a high prevalence. All over the world, an estimated 300 million people of all ages suffer from depression. The relevance between depression and DM is a well - known condition.AIM: We aimed in this study to find out the prevalence of depression symptoms for DM in an attempt to better manage the disease.METHODS: We preferred the Beck Depression Index (BDI) to evaluate the depression symptoms.RESULTS: The number of patients introduced the study were 171 (101 (59.1%) female). As a results of BDI 67 (39.2%) patients evaluated as normal [29 (28.7%) female], 54 (31.6%) had poor symptoms [35 (34.7%) female], 46 (26.9%) had moderate symptoms [34 (33.7%) female] and lastly only 4(2.3%) had strong symptoms 3 (3.0%) female]. So 50 (29.2%) of patients had median plus strong symptoms. There were statistically significant association between HbA1c stages and depression (P = 0.018).CONCLUSION: Being a patient with DM is a strong indicator that the patient may have a depressive disorder. So the physician who takes care patients with DM should be alert about depression, and the simplest way to accomplish is BDI.

scholarly journals Clinical and Neurological Symptoms in Acute Brain Stroke from Gender Dymorphism and Age Features

2021 ◽  
Vol 04 (10) ◽  
Author(s):  
N.M. Vakhabova ◽  
Keyword(s):  
Social Problems ◽  
Neurological Symptoms ◽  
Cerebral Stroke ◽  
Stroke Outcomes ◽  
Cerebrovascular Accidents ◽  
Clear Tendency ◽  
The World ◽  
Brain Stroke ◽  
Age Features ◽  
Acute Cerebral Stroke

To date, CVD, in particular acute cerebrovascular accidents, have a clear tendency to increase. The existing domestic and especially foreign literature testifies to the established important medical and social problems of acute cerebral stroke in the society of humanity around the world. Stroke can develop at any age, but its frequency and prevalence increase with age. About 80% of strokes occur in people over 65, with age having a major impact on stroke outcomes.

COGNITIVE FUNCTIONS AFTER CEREBRAL STROKE

2021 ◽  
pp. 176-180
Author(s):  
Akhmadeeva L.R. ◽  
Bulyakova G.A. ◽  
Valiev V.S.
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Functions ◽  
Cognitive Rehabilitation ◽  
Modern Society ◽  
Rehabilitation Medicine ◽  
Cerebral Stroke ◽  
Medicine Research ◽  
Number Of Patients ◽  
The Mean ◽  
Cognitive Deficiency

Cognitive deficiency is often present and recognized in patients – stroke-survivors in different stages of strokes. This is a huge problem of the modern society because patients with cognitive decline have less rehabilitation capacities, less motivation, more risks of the second vascular event. We analyzed the results of our clinical tests in a small number of patients who were hospitalized for medical-and-psychological rehabilitation. We performed several assessments for evaluating cognitive and psychological deficiency in them. The mean age of our patients was 63 years, and more than 75% of them had strokes in carotid arteries. We diagnosed mild (60%) and moderate (33.4%) cognitive impairment in this cohort. The group was asked to give their opinion about the quality of life that they had. The mean number was 5.7 out of 10 using visual analogues scale. The lower were the cognitive functions, the less obvious were emotional problems and affective disorders in the patients of this study. Cognitive rehabilitation is one of the modern and promising directions in rehabilitation medicine. Research papers published worldwide and some results of this pilot study indicate the better prognosis for patients with less cognitive impairment.

scholarly journals Rehabilitation of patients who suffered an ischemic stroke by methods of ozonotherapy, kinesiotherapy, physiotherapy and acupuncture

2018 ◽  
pp. 23-29
Author(s):  
I. Dovguy ◽  
N. Svyrydova
Keyword(s):  
Cerebrovascular Diseases ◽  
The Body ◽  
Oxygen Mixture ◽  
Cerebral Stroke ◽  
Glucose Levels ◽  
Economic Significance ◽  
Neuronal Membranes ◽  
Structural And Functional Properties ◽  
The World ◽  
Patients With Diabetes

Among the cerebrovascular diseases of the acute cerebrovascular accident, so-called clinical practice, cerebral stroke is characterized by a special gravity of the course and a high percentage of adverse outcome. In the world annually 16 million strokes are registered, the socio-economic significance of the problem is caused, in the considerable disability of patients, the number of which in the world is more than 60 million. Under the influence of the ozone-oxygen mixture in the blood of ozone are formed that move with the flow of blood throughout the body. Much of the ozonides penetrate the brain through the blood-brain barrier, where they provide, first of all, the membrane-stabilizing effect, by improving the structural and functional properties of the lipid layer of the neuronal membranes. Ozone therapy can lower blood glucose levels, so it is important for the prevention of stroke, especially in patients with diabetes, in addition to its effects on cellular metabolism and the stimulation of endogenous mechanisms to combat chronic oxidative stress.

scholarly journals Do spirometry for patients with cardiovascular diseases?

2013 ◽  
Vol 10 (2) ◽  
pp. 69-74 ◽  
Author(s):  
B M Nazarov ◽  
K A Zykov ◽  
L G Ratova ◽  
O Yu Agapova ◽  
Yu A Dolgusheva ◽  
...  
Keyword(s):  
Clinical Course ◽  
Epidemiological Studies ◽  
Chronic Obstructive ◽  
Geriatric Population ◽  
Obstructive Pulmonary Disease ◽  
Inappropriate Treatment ◽  
Number Of Patients ◽  
High Prevalence ◽  
The World ◽  
The Relationship

In recent decades cardiovascular (CVD) and COPD diseases are widespread around the world, leading to a high prevalence of patients with comorbidity, especially arterial hypertension (AH) and chronic obstructive pulmonary disease (COPD) and/or bronchial asthma (BA). The growing number of patients with this comorbidity is due to increased hypertension, COPD, and asthma comorbidities, with the increase of the geriatric population of patients with these pathologies. Epidemiological studies have shown that the deterioration of lung function is as strong a predictor of cardiovascular mortality, as well as major cardiovascular risk factors. However, spirometry in patients with CVD is carried out infrequently. Inadequate spirometric diagnostics of COPD and asthma, especially in patients with cardiovascular disease, affects the clinical course of both diseases, leading to inappropriate treatment and poor prognosis for the patient. The need for extensive screening spirometry in all patients with CVD is not proven. Thera are no spirometry reference values in patients with CVD, which makes it almost impossible to use these parameters in stratification of CV risk. This dictates the need for further research to clarify the relationship between the severity and characteristics of the various CVD and spirometric parameters.

Cerebral circulation disorder is the most important medical and social problem. Organization and development prospects of care for patients with cerebral stroke in the Republic of Tatarstan

2003 ◽  
Vol XXXV (1-2) ◽  
pp. 58-61
Author(s):  
M. F. Ismagilov
Keyword(s):  
Social Problem ◽  
Death Rate ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Age Group ◽  
Upward Trend ◽  
The Past ◽  
The World ◽  
The Republic ◽  
Development Prospects

At the turn of the second and third millennia, cerebrovascular diseases (CVD), especially their most severe forms - cerebral strokes (MI), acquired the significance of the most important medical and social problem, posing a great threat to the health of the nation. According to the yearbook of world sanitary statistics, over the past 30 years, the total indicators of MI morbidity and mortality from it in many countries of the world have a clear upward trend. By 1995, out of 31 European states, only in three countries in the age group from 25 to 74 years, the death rate from MI was above 200 per 100 thousand of the population: this is Portugal - 219.0, Bulgaria - 232.3 and Russia - 245, 6

Correction of functional constipation in patients with limited mobility after stroke

2019 ◽  
Vol 1 (6) ◽  
pp. 53-55
Author(s):  
M. S. Turchina ◽  
M. V. Bukreeva ◽  
L. Yu. Korolyova ◽  
Zh. E. Annenkova ◽  
L. G. Polyakov
Keyword(s):  
Quality Of Life ◽  
Chronic Constipation ◽  
Functional Constipation ◽  
Cerebrovascular Diseases ◽  
Medical Rehabilitation ◽  
Stroke Patients ◽  
Limited Mobility ◽  
Complete Restoration ◽  
The World

Currently, the problem of early rehabilitation of stroke patients is important, since in terms of the prevalence of cerebrovascular diseases and disability after suffering a stroke, Russia is one of the first places in the world. The complex of medical rehabilitation of such patients should provide for the early and most complete restoration of all body functions, patient education for lost skills, re-socialization of the patient and improvement of the quality of life. One of the factors contributing to a significant reduction in the quality of life after a stroke is the development of chronic constipation. The article reflects the modern methods of correction of chronic constipation in patients with limited mobility.

Desecularization as Phenomenon at the Turn of 21st Century

2019 ◽  
Vol 29 ◽  
pp. 49-57
Author(s):  
Sergey V.  Lebedev ◽  
Galina N.  Lebedeva
Keyword(s):  
21St Century ◽  
Social Problems ◽  
European Countries ◽  
Islamic Revolution ◽  
Islamic Movement ◽  
The World ◽  
Rational Alternative ◽  
Role Of Religion

In the article the authors note that since the 1970s, with the rise of the Islamic movement and the Islamic revolution in Iran, philosophers and political scientists started to talk about religious renaissance in many regions of the world. In addition, the point at issue is the growing role of religion in society, including European countries that have long ago gone through the process of secularization. The reasons for this phenomenon, regardless of its name, are diverse, but understandable: secular ideologies of the last century failed to explain the existing social problems and give them a rational alternative.

Analysis of the involvement of single nucleotide polymorphisms of redox-homeostasis genes in the development of isolated and comorbid cardioand cerebrovascular diseases

2020 ◽  
pp. 37-49
Author(s):  
О.Ю. Бушуева
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Redox Homeostasis ◽  
Total Sample ◽  
Cerebrovascular Diseases ◽  
Cerebral Stroke ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Gender And Age ◽  
Additive Regression Model ◽  
Additive Regression

Распространенные и зачастую сочетающиеся кардио- и цереброваскулярные заболевания (КЦВЗ), включающие артериальную гипертензию (АГ), ишемическую болезнь сердца (ИБС) и мозговой инсульт (МИ), представляют собой основную причину смертности во всем мире. Окислительный стресс имеет множество патологических эффектов на сосудистый гомеостаз и в настоящее время рассматривается как один из общих механизмов развития КЦВЗ. Целью исследования было изучение ассоциации однонуклеотидных полиморфизмов генов редокс-гомеостаза rs2070424 SOD1, rs4880 SOD2, rs769214 CAT, rs713041 GPX4, rs41303970 GCLM, rs17883901 GCLC, rs854560 PON1, rs7493 PON2, rs1695 GSTP1, rs2266782 FMO3 с развитием изолированных и сочетанных форм КЦВЗ. Материалом для исследования послужила выборка неродственных индивидов славянского происхождения, общей численностью 2702 человека. В исследование вошли 1815 пациентов с различными кардио- и цереброваскулярными заболеваниями и их сочетаниями: с изолированной АГ (иАГ), с изолированной ишемической болезнью сердца (иИБС), с сочетанием АГ и ИБС (АГ+ИБС), с мозговым инсультом (МИ) на фоне АГ (АГ+МИ); с коморбидной кардио- и цереброваскулярной патологией (АГ+ИБС+МИ). Из общей выборки здоровых лиц (N=887) были сформированы 5 контрольных групп, соответствующих по полу и возрасту каждой из групп нозологических форм заболеваний. Генотипирование SNP проводили методом ПЦР в режиме реального времени путем дискриминации аллелей с помощью TaqMan-зондов. Для анализа ассоциаций генотипов с развитием заболеваний пользовались лог-аддитивной регрессионной моделью. Все расчеты выполнены относительно минорного аллеля; введены поправки на пол и возраст. SNP rs1695 GSTP1 был связан исключительно с развитием иАГ (OR=1,19, 95%CI=1,01-1,39, р=0,034). SNP rs7493 PON2 был связан с развитием всех исследованных коморбидных кардио- и цереброваскулярных заболеваний: АГ+ИБС (adjOR=1,32, adj95%CI=1,07-1,63, adjp=0,01); АГ+МИ (adjOR=1,79, adj95%CI=1,45-2,21, adjp<0,0001); АГ+ИБС+МИ (adjOR=1,51, adj95%CI=1,09-2,09, adjp=0,01), а также с укорочением протромбинового времени (adjDifference=-0,35; adjp=0,01). SNP rs2266782 FMO3 был связан с фенотипом АГ+МИ (adjOR=1,24, adj95%CI=1,02-1,51, adjp=0,03), а также снижал возраст манифестации МИ (adjDifference=-2,31; adjp=0,03). Таким образом, установлено, что однонуклеотидные полиморфизмы генов редокс-гомеостаза могут представлять важную генетическую компоненту формирования дифференцированности кардио- и цереброваскулярных фенотипов. Common and often comorbid cardio- and cerebrovascular diseases (CCVD), including arterial hypertension (AH), coronary heart disease (CHD), and cerebral stroke (CS), are the leading cause of death worldwide. Oxidative stress has many pathological effects on vascular homeostasis and is currently regarded as one of the common mechanisms for the development of CCVD. The aim of our study was to investigate the association of single nucleotide polymorphisms of the redox-homeostasis genes rs2070424 SOD1, rs4880 SOD2, rs769214 CAT, rs713041 GPX4, rs41303970 GCLM, rs17883901 GCLC, rs854560 PON1, rs7493 PON2, rs1695 GSTP1, rs2266782 FMO3 with the development of isolated and comorbid CCVD. A total 2702 individuals of Slavic origin were included for this study. The patients group included 1815 subjects with various CCVD and their combinations: isolated AH (IAH); isolated IHD (IIHD), combination of AH and IHD (AH+IHD); combination of AH and CS (AH+CS); comorbid cardio- and cerebrovascular pathology (AH+IHD+CS). From the total sample of healthy individuals (N=887), 5 sex- and age-matched control groups were formed. Genotyping was performed using TaqMan-based PCR. To analyze the associations of genotypes with the risk of diseases, a log-additive regression model was used. All calculations were performed relative to the minor allele; corrections for gender and age have been introduced. SNP rs1695 GSTP1 was associated with IAH exclusively (OR=1.19, 95%CI=1.01-1.39, P=0.034). SNP rs7493 PON2 was associated with the development of all studied comorbid CCVD: AH+IHD (adjOR=1.32, adj95%CI=1.07-1.63, adjP=0.01); AH+CS (adjOR=1.79, adj95%CI=1.45-2.21, adjP<0.0001); AH+IHD+CS (adjOR=1.51, adj95%CI=1.09-2.09, adjP=0.01), as well as shortening of prothrombin time (adjDifference=-0.35; adjP=0.01). SNP rs2266782 FMO3 was associated with the development of AH+CS (adjOR=1.24, adj95%CI=1.02-1.51, adjP=0.03), as well as decreased age of manifestation of CS (adjDifference=-2.31; adjP=0.03). Thus, it was found that genes involved in regulation of redox-homeostasis, can represent an important genetic component in the formation of differentiation of cardio- and cerebrovascular phenotypes.

Mechanisms Involved in Glycemic Control Promoted by Exercise in Diabetics

2019 ◽  
Vol 15 (2) ◽  
pp. 105-110 ◽  
Author(s):  
Eric Francelino Andrade ◽  
Víviam de Oliveira Silva ◽  
Débora Ribeiro Orlando ◽  
Luciano José Pereira
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Disease ◽  
Skeletal Muscle ◽  
Glycemic Control ◽  
Sedentary Lifestyle ◽  
World Population ◽  
Pharmacological Interventions ◽  
High Prevalence ◽  
The World ◽  
Main Factors

Introduction: Diabetes mellitus is a metabolic disease characterized by high glycemic levels for long periods. This disease has a high prevalence in the world population, being currently observed an increase in its incidence. This fact is mainly due to the sedentary lifestyle and hypercaloric diets. Non-pharmacological interventions for glycemic control include exercise, which promotes changes in skeletal muscle and adipocytes. Thus, increased glucose uptake by skeletal muscle and decreased insulin resistance through modulating adipocytes are the main factors that improve glycemic control against diabetes. Conclusion: It was sought to elucidate mechanisms involved in the improvement of glycemic control in diabetics in front of the exercise.

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