scholarly journals 034 INCORPORATION OF USEFUL TRAITS FROM NATIVE ALMOND SPECIES INTO CULTIVATED ALMOND VARIETIES

HortScience ◽  
1994 ◽  
Vol 29 (5) ◽  
pp. 432e-432
Author(s):  
Dale E. Kester ◽  
Thomas M. Gradziel
Keyword(s):  
Yield Potential ◽  
Gene Introgression ◽  
Early Maturity ◽  
Breeding Lines ◽  
The Third ◽  
Hard Shell ◽  
Commercial Breeding ◽  
Third Line ◽  
Selection Of ◽  
Prunus Webbii

Approximately twenty native almond species have been described. Representative germplasm from seven of these are present in UC collections and have been used in crossing. Three specific breeding lines utilizing these species are described. One (1980 series) involved increasing yield potential through selection of high blossom density following gene introgression from Prunus fenzliana. A second involved incorporation of self-fertility, late bloom, smaller tree size, early maturity, high blossom density, and desirable nut characters from Prunus webbii into commercial breeding lines. A self-fertile selection resembling `Nonpareil' has been obtained from this material. The third line involves transmission of a unique thin, netted-surfaced, hard-shell phenotype from Prunus argentea.

scholarly journals 523 PB 489 INCORPORATION OF USEFUL TRAITS FROM NATIVE ALMOND SPECIES INTO CULTIVATED ALMOND VARIETIES. II. GENE INTROGRESSION

HortScience ◽  
1994 ◽  
Vol 29 (5) ◽  
pp. 506d-506
Author(s):  
Thomas M. Gradziel ◽  
Dale E. Kester
Keyword(s):  
Gene Pool ◽  
Prunus Dulcis ◽  
Tree Size ◽  
Gene Introgression ◽  
Breeding Lines ◽  
Commercial Use ◽  
Selected Traits ◽  
Prunus Webbii

Breeding lines have been developed incorporating introgressed genes from three native almond species Prunus fenzliana, Prunus webbii and Prunus argentea. Selected traits include self-fertility and autogamy, late bloom, smaller tree size, early nut maturity, improved cropping potential, and a well-sealed shell (endocarp) with high kernel/shell crack-out percentages. Fertility barriers, while present were easily overcome though linkage to introgressed genes with undesirable phenotypes remains an important obstacle to commercial use. Current breeding results, however, support a general conclusion that the wide diversity present within the range of species related to the cultivated almond (Prunus dulcis) provides an valuable gene pool for variety improvement.

Integration of neuropathy-sparing multimetronomic bevacizumab and multibiochemical modulation followed by regional consolidation and maintenance therapy for refractory ovarian cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e15576-e15576
Author(s):  
Howard Bruckner ◽  
Alison Emily Brandeis ◽  
Amir Reza Radjabi ◽  
Ruslan Mull ◽  
Jeanetta Stega ◽  
...  
Keyword(s):  
Low Dose ◽  
Cost Savings ◽  
Disease Models ◽  
The Third ◽  
Windows Of Opportunity ◽  
Third Line ◽  
Multiple Drugs ◽  
Very High ◽  
Selection Of

e15576 Background: In vitro disease models predicted advantages for use of 1/2-1/4 standard cytotoxic doses and selection of drugs each of which simultaneously interact with multiple drugs. Methods: Treatment (rx) combined 10mg/kg bevacizumab (B) q 2 weeks, cyclophosphamide (Cy) 400mg/m2 modified AC (Garcia Gyn Onc 05) with low dose GFLIP (carboplatin=P) P -/+ docetaxel (D) (Bruckner, ASCO 08). Regional therapy followed: +/- intraperitoneal, target directed or D+cisplatin, +/- or empirical HIPEC. To prevent further neuropathy, present in 8 of 10 pts, D was reserved for late addition (as needed) to create less than 0.5cm or otherwise “eligible for reduction surgery” tumors. Results: Overall S is 8/10 and 4/6 @ 6 and 12 mos. Two lead pts S at 18+ mos. 10/10 tumor marker responses (R); 9/10 objective R all with benefit. Patients (pts) had failed a median of 3 prior regimens and all had large rapidly worsening tumors during prior rx; 6/10 were considered “entirely untreatable.” There were no grade 4 complicated AEs, other than anemia. Epistaxis and HTN were minor, easily controlled AEs. Three deaths due to disease: One pt, PS3, refused surgery for a preexisting bowel obstruction and one, PS3, required weekly paracentesis and had sb obstruction. She relapsed after four mos OR. The third, PS4, pt was paracentesis and thorocentesis dependent and had a 6 mos OR. Median PFS is not yet reached. The lead pt, a 33yo third line, twice operated achieved a pCR in 4 mos, now stoma reversed, unmaintained for 14+ mos, following vaccine rx. Seven had OR without D; brief addition of D; brief addition of D produced 3/3 OR, a pCR, CR and PR. IRB provided prospective oversight of consent. Conclusions: This is an active multi-drug, in theory, anti BRCA rx, for very high risk and some otherwise “untreatable” pts. Simultaneous modulation of multiple drugs, both metronomically, six ways, (Cy-GFIC-D) and biochemically, up to five ways "each," 15 ways (5+4+3+2+1), is safe. Algorithms can offer cost savings (for B) by selecting a finite, short, “best” period for rx and then definitive, B free, consolidation rx. B driven response can create new windows of opportunity for test worthy multidisciplinary rxs.

Yield of Peanut Genotypes Resistant to Root-Knot Nematodes1

1998 ◽  
Vol 25 (2) ◽  
pp. 119-123 ◽  
Author(s):  
J. L. Starr ◽  
C. E. Simpson ◽  
T. A. Lee
Keyword(s):  
Nematode Resistance ◽  
Yield Potential ◽  
High Yield ◽  
Root Knot Nematode ◽  
Population Densities ◽  
Breeding Lines ◽  
Pod Yield ◽  
The Third ◽  
Field Plots ◽  
High Yield Potential

Abstract Yields of six runner-, two spanish-, and one virginia-type breeding lines of peanut with resistance to the root-knot nematode, Meloidogyne arenaria, were compared to yields of susceptible cultivars in nematode-infested and noninfested field plots in 1996. Pod yields of resistant runner-, virginia-, and one of the spanish-type breeding lines were 1.5 to 4 times greater (P = 0.05) than pod yields of the susceptible cultivars Florunner, NC-7, and Tamspan 90 in two nematode-infested fields. Final nematode population densities on most resistant breeding lines were lower (P = 0.05) than those on the susceptible cultivars. In the noninfested field, all but one runner- and the two spanish-type resistant breeding lines had pod yields that were not different from that of the susceptible cultivars. Yields of the resistant breeding lines ranged from 3890 to 5152 kg/ha in the noninfested field. In 1997, yields of three of the runner-type breeding lines were compared to the yields of Florunner and Tamrun 96 in three fields not infested with M. arenaria. In one field, no differences were observed in pod yield among the breeding lines and cultivars; in the second field the yield of two of the breeding lines were not different from the susceptible cultivars; and in the third field, only TP259-3-5 had pod yield equivalent to that of the susceptible cultivars. These data indicate that resistant runner-type genotypes with high yield potential have been developed, but additional breeding efforts are needed to develop nematode resistance in high yielding spanish- and virginia-type peanuts.

scholarly journals CANINE SYSTEMIC LUPUS ERYTHEMATOSUS

1971 ◽  
Vol 134 (2) ◽  
pp. 417-438 ◽  
Author(s):  
Robert M. Lewis ◽  
Robert S. Schwartz
Keyword(s):  
Rheumatoid Factor ◽  
Lupus Erythematosus ◽  
Infectious Agent ◽  
Lymphoid Follicle ◽  
Normal Male ◽  
Reticulum Cell ◽  
Reticulum Cell Sarcoma ◽  
Breeding Lines ◽  
The Third ◽  
Third Line

Three breeding lines, originating from dogs with SLE, have been established. Two lines were initiated by mating a female with SLE with a normal male. The third line resulted from a mating of two affected dogs. Brother-to-sister matings have reached the third generation in each line. In addition, backcross and outcross matings were carried out. More than one-third of the autopsied dogs had thymic abnormalities. The commonest lesion was a lymphoid follicle; the thymus of one dog contained multiple granulomas, and in one animal a reticulum cell sarcoma of the thymus was found. Multiple serological abnormalities, including positive LE cell tests, anti-nuclear antibodies (ANA), and rheumatoid factor, were found in the progeny. The development of ANA appeared unrelated to the incidence of positive LE cell tests. About 10% of the animals had rheumatoid factor in their serum. Control populations of dogs; including house pets; two other, unrelated lines of inbred dogs; and normal dogs housed in the same facility as the SLE colony did not have these abnormalities. The incidence of positive LE cell tests in the inbred, backcross, and outcross matings was not consistent with any conventional genetic mechanism of inheritance. It is conceivable that the results can be explained by vertical transmission of an infectious agent in a genetically susceptible individual.

scholarly journals Pregabalin Attenuates Carboplatin-Induced Akathisia-Like Neuropathy: A Novel Case Report

2021 ◽  
pp. 1418-1421
Author(s):  
Yoshitaka Saito ◽  
Yoh Takekuma ◽  
Megumi Furuta ◽  
Mitsuru Sugawara
Keyword(s):  
Symptom Improvement ◽  
Pleural Mesothelioma ◽  
Line Treatment ◽  
Action Mechanism ◽  
The Third ◽  
Third Line ◽  
Significant Symptom ◽  
Third Line Treatment ◽  
Selection Of

Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most serious adverse effects of chemotherapy. We experienced carboplatin (CBDCA)-induced akathisia-like CIPN, which was significantly attenuated by pregabalin administration, and report its treatment. A man in his 40s was administered CBDCA + pemetrexed (PEM) as the third-line treatment for recurrent malignant pleural mesothelioma. He rarely experienced mild akathisia-like symptoms on his feet before the diagnosis. The patient claimed that he exhibited mild degradation of the symptoms in the previous cisplatin (CDDP) + PEM treatment without the need for pharmacotherapy. Symptoms notably worsened approximately 7 days after the first cycle of CBDCA + PEM and did not disappear. Furthermore, symptoms worsened during the daytime and became milder at night. Lorazepam (0.5 mg) was administered 3 times a day from day 14 but was not effective. Finally, we evaluated the symptoms to be derived from CBDCA-induced neuropathy as he experienced the same symptoms in CDDP + PEM and did not have suspicious pathology or medicines for akathisia development. We decided to administer 75 mg pregabalin twice daily, resulting in significant symptom improvement. He also complained that he felt the symptoms 10 h after the previous pregabalin dose, suggesting that pregabalin was effective, and its effect weakened or disappeared as time progressed. Akathisia-like symptoms caused by CBDCA-induced CIPN are rare, but they significantly reduce the quality of life. Pregabalin was significantly effective in this case; therefore, we suggest that a detailed symptom interview and selection of the medicine, based upon the action mechanism, are necessary.

Displace of Documentary Heritage from the Soviet Union to Poland during the Third Decade of the XXth Century

2014 ◽  
Vol 3 ◽  
pp. 127-137
Author(s):  
Tatsiana Hiarnovich
Keyword(s):  
Soviet Union ◽  
International Agreements ◽  
Peace Treaty ◽  
Actual Process ◽  
Xxth Century ◽  
The Third ◽  
The Soviet Union ◽  
History Of ◽  
Selection Of

The paper explores the displace of Polish archives from the Soviet Union that was performed in 1920s according to the Riga Peace Treaty of 1921 and other international agreements. The aim of the research is to reconstruct the process of displace, based on the archival sources and literature. The object of the research is those documents that were preserved in the archives of Belarus and together with archives from other republics were displaced to Poland. The exploration leads to clarification of the selection of document fonds to be displaced, the actual process of movement and the explanation of the role that the archivists of Belarus performed in the history of cultural relationships between Poland and the Soviet Union. The articles of the Treaty of Riga had been formulated without taking into account the indivisibility of archive fonds that is one of the most important principles of restitution, which caused the failure of the treaty by the Soviet part.

COMPARATIVE DESCRIPTION OF MILK PRODUCTIVITY OF COWS UKRAINIAN RED-AND-WHITE DAIRY CATTLE AND UKRAINIAN BLACK-AND-WHITE DAIRY CATTLE AND HOLSTEIN BREEDS IN SERF «OLEKSANDRIVSKE»

2016 ◽  
Vol 52 ◽  
pp. 6-12 ◽  
Author(s):  
M. V. Gladiy ◽  
G. S. Kovalenko ◽  
S. V. Priyma ◽  
G. A. Holyosa ◽  
A. V. Tuchyk ◽  
...  
Keyword(s):  
Dairy Cattle ◽  
Dairy Cows ◽  
Milk Yield ◽  
Fat Content ◽  
Holstein Cows ◽  
Milk Productivity ◽  
Black And White ◽  
The Third ◽  
Fat Yield ◽  
Selection Of

The main goal of dairy breeds selection should be improving breeding and productive qualities of animals under modern conditions. The majority of farms, using native breeds to produce milk, has created optimal conditions for keeping and feeding, selection and matching, growing of replacements etc. Further improvement of created native dairy breeds for economically useful traits occurs at total use of purebred Holstein bulls (semen) of foreign selection. In order to realistically assess milk productivity (milk yield, fat content in milk and fat yield) of Ukrainian Black-and-White and Red-and-White Dairy cows should be conducted a comparative analysis of Holstein cows under the same conditions of feeding and keeping. It was established that Ukrainian Red-and-White Dairy cows were characterized by the highest milk yields for 305 days of all lactations, taken into account, the among three investigated breeds. Their milk yield during the first lactation was 5933 kg of milk, during the second – 6393 kg, the third – 6391 kg and during higher lactation – 6650 kg. Ukrainian Black-and-White Dairy cows were second by milk yield (except for the second lactation), during the first lactation – 5932 kg of milk, the third – 6462 kg and higher – 6541 kg, and Holstein cows were third, during the first lactation – 5794 kg of milk, the second – 6381 kg, the third – 6335 kg and higher – 6469 kg. The fat content was almost the same and varied within 3.49-3.58% in milk of Ukrainian Red-and-White Dairy cattle, 3.50-3.60% in milk of Ukrainian Black-and-White Dairy cattle and 3.50-3.56% in Holsteins’ milk. The difference between the breeds was within 0.01-0.04%. All the investigated breeds had predominance in fat yield for three lactations over standards of these breeds: Ukrainian Red-and-White Dairy cows from 75.1 to 93.4 kg, Ukrainian Black-and-White Dairy cows – 75.1-89.0 kg respectively and Holstein cows – 41.9-60.2 kg. It was found different level of positive correlation between milk yield and fat yield in all the cases and high correlation (r = 0.604-0.921, P < 0.001) in five cases (41.7%) Negative correlation coefficients indicate that selection of animals to higher milk yield in the herd will decrease the second trait – fat content in milk. Positive and highly significant correlation between milk yield and fat yield indicates that selection of cows in the herd to higher milk yields will increase fat yield. It was revealed that bulls were among the factors impacted the milk productivity (milk yield, fat content, fat yield) of three investigated breeds. So, the force (η²x) of father’s impact on milk yield was15.4-47.9%, fat content – 22.0-43.4% and fat yield – 14.9-47.7% taking into account a lactation and a breed. The force of lines impact (η²x) was second; it was on milk yield 6.1-24.5%, fat content – 4.1-17.1 and fat yield – 5.8-23.5%. The force of breeds impact (η²x) was last; it was on milk yield 0.3-2.9%, fat content – 0.2-0.3% and fat yield – 0.6-2.7%. So, the comparative studies of milk productivity of Ukrainian Red-and-White and Black-and-White Dairy cattle with Holsteins indicate that under similar conditions of feeding and keeping, these native breeds can compete with Holstein cattle. The milk yield for 305 days of higher lactation was 6650 kg of milk in Ukrainian Red-and-White Dairy cows, 6541 kg in Ukrainian Black-and-White Dairy cows and 6469 kg in Holsteins. It was found the inverse correlation r = -0.025-0.316 between milk yield and fat content in milk in most cases. Selection and matching of animals in the herd should be carried out simultaneously on these traits. It was found positive repeatability of milk yields between the first and second, the third and higher lactations (rs = 0.036-0.741), indicating the reliability of forecasting increase in milk productivity during the next lactations in all herd. Bulls have the greatest impact (η²x) on milk productivity among the factors taken into account: milk yield – 15.4-47.9%, fat content in milk – 22.0-43.4% and fat yield – 14.9-47.7%.

MODEL OF SOCIAL POTENTIAL OF CHILDHOOD IN THE RUSSIAN REGIONS: THE RESULTS OF EXPERIMENTS

2019 ◽  
pp. 152-162
Author(s):  
A.G. Filipova ◽  
A.V. Vysotskaya
Keyword(s):  
Third Wave ◽  
Russian Regions ◽  
The Third ◽  
Control Factors ◽  
Social Potential ◽  
System Input ◽  
Optimal Values ◽  
Fixed Ideal ◽  
And Control ◽  
Selection Of

The article presents the results of mathematical experiments with the system «Social potential of childhood in the Russian regions». In the structure of system divided into three subsystems – the «Reproduction of children in the region», «Children’s health» and «Education of children», for each defined its target factor (output parameter). The groups of infrastructure factors (education, health, culture and sport, transport), socio-economic, territorial-settlement, demographic and en-vironmental factors are designated as the factors that control the system (input parameters). The aim of the study is to build a model îf «Social potential of childhood in the Russian regions», as well as to conduct experiments to find the optimal ratio of the values of target and control factors. Three waves of experiments were conducted. The first wave is related to the analysis of the dynam-ics of indicators for 6 years. The second – with the selection of optimal values of control factors at fixed ideal values of target factors. The third wave allowed us to calculate the values of the target factors based on the selected optimal values of the control factors of the previous wave.

Iron Deficiency Chlorosis and Seed Yield in Dry Edible Beans Grown on High-pH Calcareous Soils

HortScience ◽  
1998 ◽  
Vol 33 (3) ◽  
pp. 444f-445
Author(s):  
J.W. Gonzales ◽  
D.P. Coyne ◽  
W.W. Stroup
Keyword(s):  
Iron Deficiency ◽  
Chlorophyll Content ◽  
Seed Yield ◽  
Calcareous Soils ◽  
Yield Reduction ◽  
Iron Deficiency Chlorosis ◽  
Breeding Lines ◽  
High Ph ◽  
The Third ◽  
Content Index

Iron deficiency chlorosis (FeDC) can cause significant seed yield reduction in dry beans (Phaseolus vulgaris L.) grown on high-pH calcareous soils. To determine the effects of FeDC on seed yield, and the effect of Fe-spray as a correction factor for FeDC, 22 breeding lines/cultivars were planted on high-pH (8.0), calcareous (3.2–3.5 calcium carbonate equivalent), and low-Fe (1.8–4.2 ppm DTPA) sandy clay loam Tripp soils at Mitchell and Scottsbluff in western Nebraska. A split-plot design was used with Fe treatments as main plots and breeding lines/cultivars as subplots. Three foliar sprays of Fe-EDDHA (2.4 kg·ha–1) were applied at V4, R5, and R7 dry bean growth stages, during 1996 and 1997. Leaf chlorosis was measured simultaneously by using a Minolta Chroma-meter (CIE L* a* b* color space system), a Minolta Chlorophyll-meter (chlorophyll content index), and by visual ratings (1 = normal green to 5 = severe chlorosis). In 1996 no significant Fe-spray × line interaction (P = 0.776) and Fe-spray effect (P = 0.884) on seed yield was observed. Breeding lines showed significant differences in seed yield (P = 0.0001) with WM2-96-5 being the highest-yielding line (4047 kg·ha–1). In 1997 a significant Fe spray × line interaction (P = 0.029) was observed. The cultivar Chase without Fe spray (3375 kg·ha–1), and lines WM2-96-5 (3281 kg·ha–1), WM2-96-8 (3171 kg·ha–1) with Fe spray were the highest yielding entries under those treatments. Differences in visual ratings after the third Fe spray in 1997 were significant (P = 0.004) for Fe spray × line interaction. In 1996 visual ratings were different only for breeding lines. Chlorophyll content index showed a significant Fe spray × line interaction after the second Fe spray (P = 0.022) and after the third Fe spray (P = 0.0003) in 1997.

Sign in / Sign up

Export Citation Format

Share Document