scholarly journals Role of Intravenous Dexmedetomidine as an Adjuvant in Labour Analgesia in Pre-eclampsia: A Prospective Study

2020 ◽  
Vol 5 (1) ◽  
pp. 57-60
Author(s):  
Jyothsna C ◽  
Roopa Kotha
Keyword(s):  
Prospective Study ◽  
Pregnant Women ◽  
Test Group ◽  
Labour Analgesia ◽  
Control Group ◽  
Medical College ◽  
A Prospective Study ◽  
Age Range ◽  
And Control

Background: Dexmedetomidine is a highly selective α-2 adrenergic receptor agonist with several diverse actions like sedation, anxiolysis, sympatholysis, analgesia, and decreased intraoperative anesthetic requirements (narcotic, inhalational). Intravenous (IV) dexmedetomidine can be used as an adjuvant in labour analgesia in preeclampsia patients as onset is faster and duration of analgesia is longer. Aim of the study: The aim of the study was to determine the role of intravenous Dexmedetomidine as an adjuvant in Labour analgesia in PIH.Subjects and Methods:This was a prospective study and was done in the department of Anaesthesia at Maheshwara Medical College. Our study included 60 full term pregnant women with preeclampsia, within 25 to 45 years age range. They were divided into two groups, as Test group and Control group of 30 patients each. Test group received IV Dexmedetomidine and Control group received IV Fentanyl.Results:Maximum number of cases 15/30 (50%) were in the age group 31-35 years, Majority were primigravida ie, 60% ( 36/60). Onset of analgesia was faster, duration of analgesia was longer and uterine contraction was greater with IV Dexmedetomidine as compared to IV fentanyl.Conclusion:From the present study we conclude that IV Dexmedetomidine can be used for labour analgesia in pregnant women with preecampsia and observed that onset and duration of analgesia are better and also it gives stable maternal parameters of maternal heart rate and mean blood pressure.

Role of routine fluid replacement in children undergoing tonsillectomy

1990 ◽  
Vol 104 (10) ◽  
pp. 801-802 ◽  
Author(s):  
P. S. Wilson ◽  
D. G. Snow ◽  
J. O'Connel ◽  
D. W. Proops ◽  
M. Barrow
Keyword(s):  
Blood Loss ◽  
Prospective Study ◽  
Intravenous Infusion ◽  
Intravenous Fluid ◽  
Fluid Replacement ◽  
Control Group ◽  
A Prospective Study ◽  
To Receive

AbstractIt has been suggested that children undergoing tonsillectomy would benefit from an intravenous infusion, to counteract the period of pre-operativefasting combined with the blood loss at operation.A prospective study of 50 children undergoing tonsillectomy was undertaken. The children were randomly allocated into two groups, one to receive an infusion and a control group.There were no significant differences between the two groups, although the children with an infusion had a longer mean post-operative stay.There would seem to be no role for routine intravenous fluid replacement in children undergoing uncomplicated tonsillectomy.

scholarly journals Do Statins Affect Thyroid Volume and Nodule Size in Patients with Hyperlipidemia in a Region with Mild-to-Moderate Iodine Deficiency? A Prospective Study

2018 ◽  
Vol 27 (1) ◽  
pp. 1-7
Author(s):  
Canan Demir ◽  
Cuneyd Anil ◽  
Yusuf Bozkus ◽  
Umut Mousa ◽  
Altug Kut ◽  
...  
Keyword(s):  
Prospective Study ◽  
Thyroid Function ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Thyroid Volume ◽  
Lifestyle Changes ◽  
Control Group ◽  
Nodule Size ◽  
A Prospective Study ◽  
And Control

Objective: The objective of this study was to assess the antiproliferative pleiotropic effects of statins on thyroid function, volume, and nodularity. Subjects and Methods: One hundred and six hyperlipidemic patients were included in this prospective study. The 69 patients in the statin groups received atorvastatin (16 received 10 mg and 18 received 20 mg) or rosuvastatin (20 received 10 mg and 15 received 20 mg). The 37 patients in the control group, assessed as not requiring drugs, made only lifestyle changes. Upon admission and after 6 months, all patients were evaluated by ultrasonography as well as for lipid variables (total cholesterol, high- and low-density lipoprotein cholesterol, and triglycerides) and thyroid function and structure. Results: After 6 months, no differences in thyroid function, thyroid volume, the number of thyroid nodules, or nodule size were observed in the statin and control groups. In a subgroup analysis, total thyroid volume had decreased more in patients receiving 20 mg of rosuvastatin than that in the control group (p < 0.05). Maximum nodule size had decreased more in those receiving 10 mg of rosuvastatin (p < 0.05). Conclusions: Our results suggest an association between rosuvastatin treatment and smaller thyroid volume and maximum nodule diameter; this could be attributable to the antiproliferative effects of statin therapy on the thyroid.

scholarly journals Oral Ondansetron in the Prevention of Per and Post Operative Nausea and Vomiting

1970 ◽  
Vol 18 (1) ◽  
pp. 1-4
Author(s):  
ML Rahman ◽  
MM Rahman ◽  
N Yusuf ◽  
A Ahsan ◽  
AHM Kamal
Keyword(s):  
Nausea And Vomiting ◽  
Control Group ◽  
College Hospital ◽  
Medical College ◽  
Matched Case ◽  
Post Operative Nausea ◽  
And Control ◽  
Single Blind ◽  
Oral Ondansetron

A randomized single blind study was done in the Department of Anaesthesiology, Rajshahi Medical College Hospital to demonstrate the role of ondansetron, a 5-HT3 receptor antagonist, in alleviating per and post operative nausea and vomiting in patients undergoing caeserian section (CS) under subarachnoid block (SAB). For the purpose, the incidence of per and post operative nausea and vomiting were compared between matched case (n=119) and control (n=121) groups undergoing CS under SAB. Cases received 16 mg ondansetron orally one hour prior to surgery. Anti emetic prophylaxis with single dose ondansetron resulted in significant reduction of per operative and immediate post operative (2 hours) nausea and vomiting. However, at sixth post operative hour difference in nausea and vomiting between case and control groups became less significant (<0.05). Incidence of nausea and vomiting during 1st post operative hour in ondansetron group was 4.2% and 0.84% respectively in comparison to 41.3% and 19.8% in control group. During 2nd post operative hour no incidence of nausea and/or vomiting were observed among subjects receiving ondansetron whereas in control group 29.2% and 5% subjects suffered from nausea and vomiting, respectively. Overall, ondansetron 16 mg is well tolerated and easy to use. Results of the present study revealed that ondansetron can be effectively used in preventing per operative and immediate post operative nausea and vomiting.   doi: 10.3329/taj.v18i1.3294TAJ 2005; 18(1): 1-4

scholarly journals Role of preoperative nutrition in gastro-intestinal cancer patients: a prospective study

2016 ◽  
Vol 4 (1) ◽  
pp. 131
Author(s):  
Samir Shukla ◽  
M. C. Songra ◽  
Naveen Kumar Patbamniya ◽  
M. Damor ◽  
Vijay Tyagi
Keyword(s):  
Prospective Study ◽  
Clinical Signs ◽  
Normal Diet ◽  
Control Group ◽  
Medical College ◽  
Preoperative Nutrition ◽  
Total Parentral Nutrition ◽  
One Year ◽  
Gandhi Medical College ◽  
A Prospective Study

Background:This prospective study was carried out to compare outcome and postoperative complication in patients with gastro-intestinal malignancy who received preoperative total parentral nutrition with those whom doesn’t.Methods: The study was a prospective single-centre, two-arm, conducted in department of general surgery, Gandhi Medical College and Associated Hamidia Hospital, Bhopal, Madhya Pradesh, India of one year duration, a total of 60 patients with G. I. malignancy, with or without sign of malnutrition, were included in the study. Patients were randomized and 30 patients were placed in each arm (interventional and control group) patients in the control group were asked to continue their normal feeding while interventional arm were given TPN in addition to their normal diet, for 7 to 10 days before surgery.Results:Infectious complications were more in control group, while one case each of pneumonia and sepsis was observed in patients receiving supplementation. Complications related to nutritional status of the patient like wound infection and anastomotic leak were observed only in patients without supplementation. There was no death observed in interventional group but two deaths occurred in control group.Conclusions:Preoperative nutritional support is beneficial and should be routinely used in abdominal and gastrointestinal cancer patient with or without clinical signs of malnutrition.

scholarly journals The Role of Tuan Guru on Improving Iron Intake and Minimalizing Food Restriction Behavior among Pregnant Women with Anemia

2021 ◽  
Vol 7 (1) ◽  
pp. 47
Author(s):  
Sabi'ah Khairi ◽  
Lalu Muhammad Harmain Siswanto ◽  
Heri Bahtiar ◽  
Ristrini Ristrini
Keyword(s):  
Health Promotion ◽  
Pregnant Women ◽  
Food Restriction ◽  
Intervention Group ◽  
Test Group ◽  
Control Group ◽  
Religious Leaders ◽  
Iron Intake ◽  
Post Intervention

Introduction: Anemia in pregnancy is an indirect cause maternal mortality. One of causes anemia during pregnancy is deficit of nutrient especially intake of iron. The aim of this study was to know that the role of religious leaders that called “Tuan Guru” as agent of change to improving iron intake among anemia pregnant women.Methods: This study was quasi-experimental with pre and post-test group design. 86 participants pregnant women with anemia have been recruited in this study with purposive sampling technic. They were divided in intervention group (47 participants) and control group (39 participants). This study involved Tuan Guru as main intervention to give health promotion about nutrition during pregnancy. This study used food recall as an instrument tool that it used to measure nutrient intake especially intake of iron both pre and post intervention and also used questonare to measure food restriction behaviour among anemia pregnant women. Statistical test used paired t-testResults: This study show that there were effect of religious leaders to improving the iron intake among pregnant women with anemia with p=0.01. This study also found that the habits of food restriction among pregnant women are decline between before and after intervention with p=0.00.Conclusion: Tuan Guru has a strong influence in helping to increase nutritional intake and is able to minimize the food restriction behaviour among anemia pregnant women. The result of this study can be a basis for government to make a policy related to involvement of religious leaders in health promotion.

scholarly journals Role of magnetic resonance cholangiopancreatography in diagnosing pancreatobiliary pathologies: a prospective study

2018 ◽  
Vol 5 (6) ◽  
pp. 2233
Author(s):  
Dakshayani S. Nirhale ◽  
Gaurav C. Kulkarni ◽  
Pravin Shingade ◽  
Shahaji Chavan ◽  
Tejas Sonawane ◽  
...  
Keyword(s):  
Prospective Study ◽  
Pancreatic Duct ◽  
Treatment Modality ◽  
Imaging Modality ◽  
Magnetic Resonance Cholangiopancreatography ◽  
Medical College ◽  
Non Invasive ◽  
A Prospective Study ◽  
Invasive Techniques

Background: Non-invasive techniques such as ultrasound and CT scan (abdomen and pelvis) are widely used in investigations of pancreaticobiliary disease, though easily available and cheap, have limitations in term of sensitivity. Invasive procedures like ERCP, though considered gold standard for diagnosis of pancreaticobiliary disease, requires highly skilled team of supporting doctors. MR Cholangio Pancreatography (MRCP) is evolving as an effective non-invasive imaging technique for examining patients with pancreatic or biliary diseases. The purpose is to illustrate the findings of MRCP in various abnormalities affecting the pancreaticobiliary diseases. Objective was to study the role of MRCP as non-invasive imaging modality for diagnosis of pancreatobiliary diseases, in diagnosing lower biliary tract pathologies, pancreatic duct pathologies, determining treatment modality in pancreatobiliary diseases, surgical or endoscopicMethods: This is a prospective study conducted in Dr. D. Y. Patil Medical College and Hospital, Pimpri, Pune for a period of two years from July 2015 to September 2017. 60 patients were enrolled in the study, their MRCP was performed following ultrasonography.Results: The MRCP diagnosed the following pathologies- cholelithiasis, choledocholithiasis, CBD stricture, chronic pancreatitis, choledochal cyst, cholangiocarcinoma, pseudocyst of pancreas, sclerosing cholangitis and GB perforation. Out of 60, 32 underwent surgical procedure and 20 underwent endoscopic procedure and 8 were treated medically.Conclusions: MRCP is very accurate in diagnosing CBD and pancreatic duct pathologies. Its helps in deciding the treatment modality for the same. It decides whether the patient requires ERCP and thus cuts down the rate of ‘negative’ ERCP.

Breast-feeding and asthma in children in Diwnaniya

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Nasma Naji Al-Hajjiah
Keyword(s):  
Prospective Study ◽  
Protective Effect ◽  
Breast Feeding ◽  
Control Group ◽  
Healthy Infants ◽  
Asthma In Children ◽  
A Prospective Study ◽  
And Control ◽  
The Relationship ◽  
Substantial Interest

The protective effect ofand the association between breastfeeding andasthma has raised substantial interest and is a subject of debate.to study the relationship between asthma andfeeding patterns in children up to the age of 12 years in Diwaniah, Iraq with a focus on breast feeding. This is a prospective study accomplishedin the maternity and children teaching hospital in Diwaniah, Iraq during the period from January 2015 to March 2016. The study involves 1242 patients with the diagnosis of asthma and control group of 1350 healthy infants and children were chosen for comparison. The pattern of feeding and the period of breast feeding in both groups wererecorded together with other variables. sixty six percent (688 out of 1041) of patients with asthma ≤ 5 years were artificially fed and only 13.5% of them were breast fed.the rate of asthma is significantly less in children with breast feeding especially when the age interval under five years is taken into consideration. early,exclusive andprolonged breastfeedingprotects against asthma in children particularly in those less than 5 years of age.

scholarly journals Investigation on Immunoglobulin Fortification in Preventing Infections in the Newborn

2018 ◽  
Vol 29 (5-6) ◽  
pp. 91-6 ◽  
Author(s):  
Hans Eldih Monintja
Keyword(s):  
Prospective Study ◽  
Neonatal Sepsis ◽  
Newborn Infants ◽  
Control Group ◽  
A Prospective Study

Observations in neonatal sepsis revealed that the lgG concentrations in septic newborns is significantly lower than in non septic infants. This condition lead the author to investigate the role of fortification of lgG in infants with intrapartum infections. For this purpose a prospective study was carried out, 35 newborn infants with intrapartum infections were treated with lgG Cutter 0,6 mg per Kg BW per week and 35 other infants with similar criteria served as control group. The result of the trial showed that /gG administration could help in prevention of minor infections.

scholarly journals Coagulation tests or Standardized questionnaire, which is better as a predictor of bleeding? A prospective study among children before tonsillectomy and/or adenoidectomy.

2020 ◽  
Author(s):  
Muhamed Masalha ◽  
Ari DeRowe ◽  
Salim Mazzawi ◽  
Tzvi chen ◽  
Rami Ghanayim ◽  
...  
Keyword(s):  
Prospective Study ◽  
Bleeding Events ◽  
Risk Of Bleeding ◽  
Coagulation Testing ◽  
Coagulation Tests ◽  
A Prospective Study ◽  
Medical Questionnaire ◽  
Age Range ◽  
Routine Coagulation

Abstract Objective: The value of pre-operative coagulation testing for adenotonsillar surgery is controversial. The purpose of this study was to evaluate the role of routine coagulation tests and a standardized questionnaire in children before tonsillectomy and/or adenoidectomy. Results: A total of 143 children were prospectively enrolled in the study between 2013 and 2017, 81 males (56.6%) and 62 females (43.4%), age range 1 to 18 years (median age 5 years). Eighteen bleeding events were documented, three of them required treatment in the operating room. Abnormal coagulation tests were not associated with higher odds of bleeding after surgery. Higher risk of bleeding (p=0.01) was associated with an abnormal standardized medical questionnaire.

scholarly journals Short-term Success of Osseointegrated Dental Implants in HIV-positive Individuals: A Prospective Study

2007 ◽  
Vol 8 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Catherine M. Flaitz ◽  
C. Mark Nichols ◽  
Gene C. Stevenson ◽  
Patricia C. Riano ◽  
Antonio J. Moretti ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Prospective Study ◽  
Success Rate ◽  
Dental Implants ◽  
Test Group ◽  
Hiv Positive ◽  
Control Group ◽  
Short Term ◽  
A Prospective Study ◽  
Hiv Negative

Abstract Purpose Except for the occasional case report, there are no studies evaluating the success rate of osseointegrated dental implants in individuals infected with the human immunodeficiency virus (HIV). This study investigated the short-term clinical outcome of implant placement in a group of HIV-positive and HIV-negative individuals who required complete dentures. Methods and Materials Edentulous subjects were recruited from an HIV-dedicated clinic and a dental school clinic. Two BioHorizons® dental implants were placed in the anterior mandible to support an overdenture opposing a maxillary denture. Outcome measurements obtained six months after activation of implants were presence of pain, mobility, soft tissue status, and radiographic bone level. Descriptive statistics were used. Results Twenty-nine edentulous adults, including 20 HIV-positive subjects (test) and nine HIV-negative subjects (control), participated. The test group had six females, 14 males; 13 Whites, four African-Americans, and three Hispanics with a mean age of 48.9 years (range: 35-59). The mean CD4 count was 467 cells/mm3 (range: 132-948). The control group had six females, three males; seven Whites, and two Hispanics with a mean age of 65.3 years (range: 50-82). Short-term success rate was 100% for both groups. No difference in clinical outcome was found between the groups. Conclusion This study demonstrated dental implants are well tolerated and have predictable outcomes for HIV-infected individuals for the duration of the study and probably over an even longer term. Citation Stevenson GC, Riano PC, Moretti AJ, Nichols CM, Engelmeier RL, Flaitz CM. Short-term Success of Osseointegrated Dental Implants in HIV-positive Individuals: A Prospective Study. J Contemp Dent Pract 2007 January;(8)1:001-010.

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