Association Between Blood Pressure Indicators and Stroke in Aged Population: A Community-Based Nested Case-Control Study

SummaryThe elevated risk of suicide in prison and after release is a well-recognised and serious problem. Despite this, evidence concerning community-based offenders' suicide risk is sparse. We conducted a population-based nested case–control study of all people in a community justice pathway in England and Wales. Our data show 13% of general population suicides were in community justice pathways before death. Suicide risks were highest among individuals receiving police cautions, and those having recent, or impending prosecution for sexual offences. Findings have implications for the training and practice of clinicians identifying and assessing suicidality, and offering support to those at elevated risk.

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Determinants of perinatal mortality among cohorts of pregnant women in three districts of North Showa zone, Oromia Region, Ethiopia: Community based nested case control study

BMC Public Health ◽

10.1186/s12889-018-5757-2 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 8

Author(s):

Elias Merdassa Roro ◽

Mitike Molla Sisay ◽

Lynn M. Sibley

Keyword(s):

Pregnant Women ◽

Perinatal Mortality ◽

Case Control Study ◽

Case Control ◽

Community Based ◽

Nested Case Control ◽

Control Study

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Determinants of skilled attendance for delivery in Northwest Ethiopia: a community based nested case control study

BMC Public Health ◽

10.1186/1471-2458-13-130 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 36

Author(s):

Zelalem Birhanu Mengesha ◽

Gashaw Andargie Biks ◽

Tadesse Awoke Ayele ◽

Gizachew Assefa Tessema ◽

Digsu Negesse Koye

Keyword(s):

Case Control Study ◽

Case Control ◽

Northwest Ethiopia ◽

Community Based ◽

Skilled Attendance ◽

Nested Case Control ◽

Control Study

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Relationship between serum lipid levels and ischemic stroke in patients with atrial fibrillation: a nested case–control study based on the China Atrial Fibrillation Registry

BMC Cardiovascular Disorders ◽

10.1186/s12872-021-02237-6 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Fei Li ◽

Xin Du ◽

Liu He ◽

Chao Jiang ◽

Shijun Xia ◽

...

Keyword(s):

Atrial Fibrillation ◽

Blood Pressure ◽

Ischemic Stroke ◽

Case Control Study ◽

Density Lipoprotein ◽

Case Control ◽

Control Group ◽

Stroke Group ◽

Nested Case Control ◽

Control Study

Abstract Background Atrial fibrillation (AF) is an important risk factor for acute ischemic stroke. Methods A nested case–control study was conducted among patients diagnosed with AF, whose information was acquired from the prospective China Atrial Fibrillation Registry (China-AF), from August 2011 to December 2018. Results This study compared patients with stroke group (n = 145) with a matched control group (n = 577). Demographic data were similar except for body mass index (BMI), diastolic blood pressure (DBP) which were higher, and new oral anticoagulant (NOAC) treatment rate which was lower in the stroke group (all P < 0.05). Baseline median [IQR] levels of including triglyceride (TG) were higher in the stroke group (21.96 [16.74, 21.52], mg/dL) than the control group (19.62 [14.76, 27.36], mg/dL) (P = 0.012), while the total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C) were similar between the two groups. Elevated TG and HDL-C were positively associated with ischemic stroke (OR 1.01, 95% CI 1.00–1.02, P = 0.032; OR 1.03, 95% CI 1.00–1.05, P = 0.025), after adjustment for BMI, systolic blood pressure, DBP, CHA2DS2-VASc score, HAS-BLED score, NOAC, LDL-C and HDL-C. However, NOAC (OR 0.20, 95% CI 0.05–0.84, P = 0.029) could decrease the likelihood of ischemic stroke in patients with AF. In subgroup analysis, higher TG level remained significantly associated with ischemic stroke for AF patients without a history of smoking (OR 1.26, 95% CI 1.02–1.55, P = 0.028). Conclusion Higher level of TG and HDL-C were positively associated with ischemic stroke in patients with AF.

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Dyslipidemia Modified the Association Between Serum Uric Acid and First Hemorrhagic Stroke Among Chinese Population : A Community Based Nested Case-control Study

10.21203/rs.3.rs-124307/v1 ◽

2020 ◽

Author(s):

Hui Liu ◽

Chonglei Bi ◽

Tengfei Lin ◽

Lishun Liu ◽

Chengzhang Liu ◽

...

Keyword(s):

Uric Acid ◽

Serum Uric Acid ◽

Hemorrhagic Stroke ◽

Case Control Study ◽

Case Control ◽

Community Based ◽

Increased Risk ◽

Nested Case Control ◽

And Control ◽

Control Study

Abstract Background: Previous studies have shown that serum uric acid (SUA) and dyslipidemia are risk factors for stroke. However, it is not clear that whether dyslipidemia could modify the association between SUA and hemorrhagic stroke.Methods: We conducted a nested case-control study from “H-type Hypertension and Stroke Prevention and Control Project (HSPCP)” in China. A total of 355 first hemorrhagic stroke cases and 355 controls matched for age (± 1 years), sex and study site were included in the final data analysis. Logistic regression analysis were performed to assess the association between SUA and first hemorrhagic stroke.Results: In matched analysis, the risk of hemorrhagic stroke was associated with the increased SUA levels (OR:1.13, 95% CI:0.98 to 1.30). However, multiple regression analyses showed that per 1 mg/dL in SUA was associated with a 16% decreased risk of hemorrhagic stroke among participants without dyslipidemia and associated with a 28% increased risk of hemorrhagic stroke among dyslipidemia participants [without dyslipidemia: odds ratio (OR) = 0.84, 95% CI 0.65 to 1.09, with dyslipidemia: OR = 1.28, 95% CI 1.10 to 1.48; P Interaction ＜0.001]. The results of the subgroup analysis were consistent with the main results.Conclusions: Elevated SUA was associated with increased risk of hemorrhagic stroke especially among participants with dyslipidemia. These findings suggest that we need to focus on SUA levels especially among participants with dyslipidemia.

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