scholarly journals An Investigation of Selected Socio-Demographic Factors with Aplastic Anemia in Pakistan: A Case-Control Study

2021 ◽  
Vol Volume 14 ◽  
pp. 8929-8934
Author(s):  
Muhammad Asif Syed ◽  
Aneela Atta Ur Rahman ◽  
Abdul Ghani ◽  
Muhammad Nadeem Shah Syed ◽  
Muhammad Ilyas Siddiqui ◽  
...  
Keyword(s):  
Aplastic Anemia ◽  
Case Control Study ◽  
Demographic Factors ◽  
Case Control ◽  
Socio Demographic Factors ◽  
Control Study

CDC Kerala 12: Socio-demographic Factors Among Children (2–6 y) with Autism – A Case Control Study

2014 ◽  
Vol 81 (S2) ◽  
pp. 129-132 ◽  
Author(s):  
Babu George ◽  
M. S. Razeena Padmam ◽  
M. K. C. Nair ◽  
M. L. Leena ◽  
Paul Swamidhas Sudhakar Russell
Keyword(s):  
Case Control Study ◽  
Demographic Factors ◽  
Case Control ◽  
Socio Demographic Factors ◽  
Control Study

The Relationship of Drug Therapy to Aplastic Anemia in Pakistan: A Hospital-Based Case Control Study

2021 ◽  
Vol Volume 17 ◽  
pp. 903-908
Author(s):  
Muhammad Asif Syed ◽  
Aneela Atta Ur Rahman ◽  
Muhammad Nadeem Shah Syed ◽  
Naveed Masood Memon
Keyword(s):  
Drug Therapy ◽  
Aplastic Anemia ◽  
Case Control Study ◽  
Case Control ◽  
Relationship Of ◽  
The Relationship ◽  
Control Study

scholarly journals Epidemiology of aplastic anemia in France: a case-control study. I. Medical history and medication use. The French Cooperative Group for Epidemiological Study of Aplastic Anemia

Blood ◽  
1993 ◽  
Vol 81 (6) ◽  
pp. 1471-1478
Author(s):  
E Baumelou ◽  
M Guiguet ◽  
JY Mary
Keyword(s):  
High Risk ◽  
Drug Use ◽  
Aplastic Anemia ◽  
Medical History ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Gold Salts ◽  
Matched Design ◽  
Control Study

Aplastic anemia (AA) is a rare, severe disease of mainly unknown origin. Numerous case history reports have incriminated drugs in the etiology of this disease. Because those reports were questionable, a case-control study was conducted in France between 1985 and 1988. Cases selected from the national register were eligible for inclusion when at least two blood lineages were depressed (hemoglobin < or = 10 g/100 mL and reticulocytes < or = 50 x 10(9)/L, granulocytes < or = 1.5 x 10(9)/L, platelets < or = 100 x 10(9)/L) and when the bone marrow biopsy was compatible with the disease. Using a standardized questionnaire, trained investigators interviewed one AA patient and two groups of controls (two hospitalized patients and one neighbor of the AA patient) matched for age, sex, and interviewer. One hundred forty- seven AA patients, 287 hospitalized controls, and 108 neighbors were interviewed. The occurrence of AA was analyzed by matched design with relation to medical history and drug use during the last 5 years, and specifically during the last year. Three times as many AA patients reported having suffered from clinical hepatitis during the last 6 months than either type of control. Similarly, a higher proportion of AA patients reported a history of chronic immune disorder, mainly rheumatoid arthritis (odds ratio of 6.8), and a previous use of gold salts and D-penicillamine in the 5 previous years (odds ratio of 4.9 for each drug). An excess of colchicine and allo/thiopurinol intake in the 5 previous years was observed among the AA patients (odds ratio equal to 4.1 and 3.6, respectively). These results for gold salts, D- penicillamine, and colchicine were confirmed when looking for drug use within the last year. A moderate risk was associated with acetaminophen or salicylate intake during the 5 previous years or during the last year (odds ratio between 1.8 and 2.0). The frequent use of salicylates within the last year was associated with a high risk of AA (odds ratio of 5.0). A high risk was also associated with indolic derivative intake but only when comparing AA patients to neighbor controls. No association could be evidenced with diclofenac intake, whatever the control group. Differences observed with recently published studies suggest that targeted studies on each category of drugs according to the treated pathologies should be initiated.

scholarly journals Effects of baby-friendly practices on breastfeeding duration in China: a case-control study

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Yue Zhang ◽  
Jinliuxing Yang ◽  
Wenhao Li ◽  
Nianrong Wang ◽  
Ya Ye ◽  
...  
Keyword(s):  
Case Control Study ◽  
Positive Impact ◽  
Case Control ◽  
Central China ◽  
Breastfeeding Duration ◽  
On Demand ◽  
One Step ◽  
Global Goal ◽  
Socio Demographic Factors ◽  
Control Study

Abstract Background The Baby-Friendly Hospital Initiative is generally considered an effective way to promote breastfeeding. Although China has the largest number of baby-friendly hospitals in the world, research on baby-friendly practices in China is limited, and the rate of exclusive breastfeeding (EBF) at 6 months, 20.7%, compared to the 2025 global goal of 50% is low. It is, therefore, important to determine the factors that remain significant barriers to EBF in China. To explore how the key baby-friendly practices affect EBF duration in China, we used a case-control study to compare the effects of baby-friendly-related practices on both EBF and non-breastfeeding (NBF) mothers at 3 months and to investigate the effects of both single and comprehensive baby-friendly practices in promoting EBF duration at 3 months, which is one step toward EBF at 6 months. Methods Participants were recruited from four maternal and child health hospitals in western (Chongqing), eastern (Qingdao), southern (Liuzhou), and central China (Maanshan). A total of 421 mothers (245 in the EBF group, 176 in the NBF group) of infants aged 3 months were surveyed through a self-reported questionnaire from April 2018 to March 2019. The experience of baby-friendly practices and breastfeeding during hospitalization were assessed with yes/no questions. Socio-demographic factors that influenced breastfeeding at 3 months were analyzed using bivariate and multivariate logistic regression analyses. Results Of mothers in the EBF group, 65.57% reported engaging in at least seven baby-friendly practices compared to 47.72% of mothers in the NBF group. Significantly more mothers in the EBF group engaged in baby-friendly practices than in the NBF group. These practices included “breastfeeding within one hour after birth” (74.29% vs. 59.09%), “breastfeeding on demand” (86.48% vs. 75.00%), and “never use a pacifier” (46.53% vs. 31.25%). After adjusting for confounding variables, we found that the mothers who engaged in fewer than seven baby-friendly practices were about 1.7 times less likely to breastfeed than were those who engaged in seven or more baby-friendly practices (odds ratio [OR] 1.720, 95% confidence interval [CI] 1.106, 2.667). Further, the mothers who did not breastfeed on demand were as likely to not breastfeed up to 3 months (OR 2.263, 95% CI 1.265, 4.049), as were mothers who did not breastfeed during hospitalization (OR 4.379, 95% CI 1.815, 10.563). Conclusions These data from hospitals in China suggest that higher compliance with baby-friendly practices may have a positive impact on EBF at 3 months, particularly in terms of promoting the implementation of breastfeeding on demand and breastfeeding during hospitalization in China.

scholarly journals Epidemiology of aplastic anemia in France: a case-control study. I. Medical history and medication use. The French Cooperative Group for Epidemiological Study of Aplastic Anemia

Blood ◽  
1993 ◽  
Vol 81 (6) ◽  
pp. 1471-1478 ◽  
Author(s):  
E Baumelou ◽  
M Guiguet ◽  
JY Mary
Keyword(s):  
High Risk ◽  
Drug Use ◽  
Aplastic Anemia ◽  
Medical History ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Gold Salts ◽  
Matched Design ◽  
Control Study

Abstract Aplastic anemia (AA) is a rare, severe disease of mainly unknown origin. Numerous case history reports have incriminated drugs in the etiology of this disease. Because those reports were questionable, a case-control study was conducted in France between 1985 and 1988. Cases selected from the national register were eligible for inclusion when at least two blood lineages were depressed (hemoglobin < or = 10 g/100 mL and reticulocytes < or = 50 x 10(9)/L, granulocytes < or = 1.5 x 10(9)/L, platelets < or = 100 x 10(9)/L) and when the bone marrow biopsy was compatible with the disease. Using a standardized questionnaire, trained investigators interviewed one AA patient and two groups of controls (two hospitalized patients and one neighbor of the AA patient) matched for age, sex, and interviewer. One hundred forty- seven AA patients, 287 hospitalized controls, and 108 neighbors were interviewed. The occurrence of AA was analyzed by matched design with relation to medical history and drug use during the last 5 years, and specifically during the last year. Three times as many AA patients reported having suffered from clinical hepatitis during the last 6 months than either type of control. Similarly, a higher proportion of AA patients reported a history of chronic immune disorder, mainly rheumatoid arthritis (odds ratio of 6.8), and a previous use of gold salts and D-penicillamine in the 5 previous years (odds ratio of 4.9 for each drug). An excess of colchicine and allo/thiopurinol intake in the 5 previous years was observed among the AA patients (odds ratio equal to 4.1 and 3.6, respectively). These results for gold salts, D- penicillamine, and colchicine were confirmed when looking for drug use within the last year. A moderate risk was associated with acetaminophen or salicylate intake during the 5 previous years or during the last year (odds ratio between 1.8 and 2.0). The frequent use of salicylates within the last year was associated with a high risk of AA (odds ratio of 5.0). A high risk was also associated with indolic derivative intake but only when comparing AA patients to neighbor controls. No association could be evidenced with diclofenac intake, whatever the control group. Differences observed with recently published studies suggest that targeted studies on each category of drugs according to the treated pathologies should be initiated.

scholarly journals Dietary zinc intake and brain cancer in adults: a case–control study

2008 ◽  
Vol 99 (3) ◽  
pp. 667-673 ◽  
Author(s):  
P. Dimitropoulou ◽  
S. Nayee ◽  
J. F. Liu ◽  
L. Demetriou ◽  
M. van Tongeren ◽  
...  
Keyword(s):  
Protective Effect ◽  
Brain Tumour ◽  
Case Control Study ◽  
Multivariate Logistic Regression Analysis ◽  
Population Based ◽  
Case Control ◽  
Multivitamin Supplementation ◽  
Socio Demographic Factors ◽  
The Uk ◽  
Control Study

Little is known about the aetiology of brain tumours. One putative factor suggested from animal models is a protective effect of dietary Zn. We tested the hypothesis that increased compared with low dietary Zn intake is protective against brain tumour development. We conducted a population-based case–control study in the UK, of adults aged 18–69 years, between 2001 and 2004 aiming to identify possible risk factors. Dietary information was collected from 637 cases diagnosed with a glioma or meningioma, and 876 controls. Data were obtained from a self-completed FFQ. Multivariate logistic regression analysis was conducted, adjusting for socio-demographic factors, season of questionnaire return, multivitamin supplementation and energy intake. Although a weak protective effect was observed for the third quartile of intake (normal compared with low intake) in the meningioma group, this was limited to the specific brain tumour subtype and quartile, and was not significant after also adjusting for intake of other elements. Overall there was no significant effect of Zn intake. No association or dose–response relationship was observed between increased compared with low Zn intake and risk of glioma or meningioma.

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